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Search Results: 1 - 10 of 465255 matches for " Alicia; Monteagudo Pe?a "
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Bases genéticas del síndrome de ovarios poliquísticos
Ovies Carballo,Gisel; Martínez de Sandelices,Alicia; Monteagudo Pea,Gilda; Sardi?as Díaz,Irelys;
Revista Cubana de Endocrinolog?-a , 2011,
Abstract: the syndrome of polycystic ovaries is the endocrine disorder involving more the reproductive sphere of the woman in fertile age, its causes are unknown with accuracy, but most of experts coincide in propose that it is a multifactor entity where the genetic factor more and more have a great significance. in past years, it has been possible to identify some genes involved in the pathogenic processes of this syndrome and among the more important are included those codifying for enzymes of the steroidogenesis, for the insulin receptor and other hormones related to the insulin action, as well as the gonadotropins and its receptors, features that are the aim of present review.
Bases genéticas del síndrome de ovarios poliquísticos Genetic bases of polycystic ovary syndrome
Gisel Ovies Carballo,Alicia Martínez de Sandelices,Gilda Monteagudo Pea,Irelys Sardi?as Díaz
Revista Cubana de Endocrinología , 2011,
Abstract: El síndrome de ovarios poliquísticos es el trastorno endocrino que más afecta la esfera reproductiva de la mujer en la edad fértil, sus causas se desconocen con exactitud, pero la mayoría de los expertos coinciden en plantear que es una entidad multifactorial, en la que los factores genéticos cada vez cobran mayor importancia. En los últimos a os se han identificado varios genes involucrados en los procesos patogénicos de este síndrome, y dentro de estos, los más importantes son aquellos que codifican para enzimas de la esteroidogénesis, para el receptor de insulina y otras hormonas relacionadas con la acción de la insulina, así como las gonadotropinas y sus receptores, aspectos sobre los cuales trata la siguiente revisión. The syndrome of polycystic ovaries is the endocrine disorder involving more the reproductive sphere of the woman in fertile age, its causes are unknown with accuracy, but most of experts coincide in propose that it is a multifactor entity where the genetic factor more and more have a great significance. In past years, it has been possible to identify some genes involved in the pathogenic processes of this syndrome and among the more important are included those codifying for enzymes of the steroidogenesis, for the insulin receptor and other hormones related to the insulin action, as well as the gonadotropins and its receptors, features that are the aim of present review.
Tecnologías de la Información y Comunicaciones
Monteagudo Pea,José Luis;
Educación Médica , 2004, DOI: 10.4321/S1575-18132004000200004
Abstract: information and communication technologies are essential to support professional research activities in biomedicine and health. their adoption and use is linked to efficiency and competitivity. after need analysis, tics applications whose knowledge is recommended, are identified. needs are referred to activities linked to the execution of research projects but also to teaching, continuous training and professional development. based on that, it is proposed a formative programme structure with different competence levels and with a combination of horizontal common general skills and vertical specialization areas. finally, it is outlighted that new technologies facilitate new instruments but also they represent new working cultures and present new ethic and legal dilemmas to the researchers that would need to be educated in new working environments.
Tecnologías de la Información y Comunicaciones Information and Communication Technologies
José Luis Monteagudo Pea
Educación Médica , 2004,
Abstract: Las Tecnologías de la Información y las Comunicaciones constituyen una herramienta fundamental para soportar las actividades profesionales de investigación en biomedicina y salud. Su adopción y uso está ligado a la eficiencia y competitividad. Tras el análisis de las necesidades se han identificado las aplicaciones TICs cuyo dominio es recomendable. Las necesidades se refieren al desarrollo de las actividades propias de los proyectos de investigación pero también de formación continuada, docencia y desarrollo profesional. Sobre la base anterior, se propone una estructura de programa formativo basado en niveles y con una mezcla de bases generales comunes de tipo horizontal y áreas de especialización vertical. Finalmente, se pone de manifiesto que las nuevas tecnologías además de facilitar nuevos instrumentos significan nuevas culturas de trabajo y presentan nuevos dilemas de carácter ético y legal para los investigadores que necesitarán formarse en nuevos entornos de trabajo. Information and Communication Technologies are essential to support professional research activities in biomedicine and health. Their adoption and use is linked to efficiency and competitivity. After need analysis, TICs applications whose knowledge is recommended, are identified. Needs are referred to activities linked to the execution of research projects but also to teaching, continuous training and professional development. Based on that, it is proposed a formative programme structure with different competence levels and with a combination of horizontal common general skills and vertical specialization areas. Finally, it is outlighted that new technologies facilitate new instruments but also they represent new working cultures and present new ethic and legal dilemmas to the researchers that would need to be educated in new working environments.
La organización y funcionamiento de la Universidad de los Andes en el siglo XIX: Estatutos y Reglamentos desde la Legislación Nacional (1832-1897)
Alicia Morales Pea
Revista Historia de la Educación Latinoamericana , 2006,
Abstract: En el siglo XIX y principios del XX la reglamentación de la Universidad venezolana sufrió sucesivos cambios que incidieron sobre el funcionamiento de la misma en lo académico y administrativo. En 1827, Simón Bolívar reforma los Estatutos de la Universidad de Caracas. Posteriormente, José María Vargas planteará la necesidad de una ley de instrucción pública que derogase la legislación educacional colombiana; pues, aunque asimilable a muchos aspectos en materia de organización, la situación venezolana reclamaba un cuerpo legal propio. Al aplicarse los primeros Estatutos Republicanos de Caracas quedaron derogados los que regían a la Universidad Colonial; dichos estatutos serían en 1832 utilizados al reiniciar sus actividades la Universidad de Mérida y adaptados a su propia realidad. Es sólo en 1840, cuando la Dirección Nacional de Instrucci ón redactó un Código de Instrucción Pública para la educación en las universidades y academias que sustituyeron los decretos de Bolívar en 1827, 1828 y 1829, en Caracas, Bogotá y Quito respectivamente, que coexistían aun después de la ruptura colombiana en 1830. En este orden de ideas, se pretende realizar una primera aproximación a la legislación de la Universidad de Mérida desde las disposiciones universitarias nacionales.
Metodología de introducción de servicios e-salud para el seguimiento y control de pacientes crónicos
Monteagudo Pea,Jose Luis; Hernández Salvador,Carlos; García-López,Fernando;
Revista Espa?ola de Salud Pública , 2004, DOI: 10.1590/S1135-57272004000500002
Abstract: a methodology is presented for a smooth, orderly implementation of specific e-health services for monitoring chronic patients outside of the hospital setting. identified as a stage-gate model for the management of the overall implementation process, this methodology is presented formally structured into three steps: a) exploratory examination (pilot project stage); 2) in-depth evaluation (clinical trial stage); and 3) deployment (guided use stage). in the first stage, controlled by the r+d team, the predominant criteria are the functionality and usability of the technologies involved. in the second stage, controlled by an associated health technology evaluation agency, the predominant criterion is the scientific aspect related to the results obtained in the clinical testing. the third stage is controlled through decisions made by the health administrations as to the implementation of new technologies and the financing thereof. a description is provided as to the requirements of the technological platform designed to serve as the medium for the projects and tests from stage 1 and 2. as an example of what is done in stage 2, a description is given of a trial related to hypertension.
Patrón hormonal de mujeres con diagnóstico clínico y ecográfico del síndrome de ovarios poliquísticos
Acosta Cede?o,Alina; Monteagudo Pea,Gilda; Menocal Alayón,Ahmed;
Revista Cubana de Endocrinolog?-a , 2004,
Abstract: the polycystic ovary syndrome (pos) is a disorder of non well defined etiology with an aberrant hormonal pattern. the results of a descriptive cross-sectional study in which 30 women with clinical hyperandrogenism and at least 2 echographic elements suggestive of pos that were determined testosterone (t), androstenedione (ad), dihydroepiandrosterone (dhea) and its sulfate (dheas), follicle stimulating hormone (fsh) and luteinizing hormone (lh), were shown. descriptive statiscians and person's correlation test were used to analyze the results. the behavior of gonadotropins was very variable. the fsh was diminished in 3 cases, normal in 24 and increased in 3, with normal mean values (5.45 ui/l). the lh had values under the range of normality in 1 case, normal in 10 and high in 19, and an elevated mean value (12.49 ui/l). the ratio lh/fsh was over 3 in 14 patients (46.6 %). the mean values of all the androgens, excepting dheas were high; in 46.6 % of the cases it was found a rise of more than one androgen, and biochemical hyperandrogenism was not proved in 4 cases. the ad and the dhea were the most frequently rised androgens (50 % each one), followed by the t (30.0) and the dhea (10.0). no correlation was observed among the studied variables. it was concluded that the association of clinical hyperandrogenism and echographic signs of pos did not guarantee uniformity in the hormonal behavior, so it is necessary to continue working to determine the diagnostic element that identifies the syndrome really.
Hipertiroidismo subclínico Subclinical hyperthyroidism
Lisbet Rodríguez Fernández,Marelys Yanes Quesada,Alina Acosta Cede?o,Gilda Monteagudo Pea
Revista Cubana de Endocrinología , 2009,
Abstract: El hipertiroidismo subclínico se define por la presencia de niveles disminuidos o no detectables de tirotropina, asociados a concentración de tetrayodotironina y triyodotironina libres dentro de parámetros normales. Su prevalencia en la población varía entre un 0,5 y un 16 % aproximadamente, y es el tratamiento con levotiroxina sódica la causa más frecuente. No siempre resulta tan asintomático, y las afectaciones principales ocurren sobre el sistema cardiovascular y óseo. Esta condición médica puede ser reversible espontáneamente. Por lo controversial del tema, el presente trabajo trata los aspectos clínicos más relevantes y la conducta a seguir. Subclinical hyperthyroidism is defined by presence of decreased o non-detected levels of thyrotropin, associated with free concentrations of tetraiodothyronine and triiodothyromime within normal parameters. Its prevalence in population differs between 0,5 % and 16 % approximately, and the sodium Levothyroxine treatment is the more frequent cause. Not always it is so asymptomatic, and main affections occur on cardiovascular and osseous system. This medical condition may be spontaneously reversible. Due to controversial of this topic, present paper approaching the more significant clinical features and the strategy to go on.
Cirugía genital: impacto psicológico y sexual. Presentación de una paciente Genital surgery: psychological and sexual impact. A case report
Adriana Agramonte Machado,Loraine Ledón Llanes,Gilda Monteagudo Pea,Madelín Mendoza Trujillo
Revista Cubana de Endocrinología , 2007,
Abstract:
Deficiencia androgénica en hombres de 60 a os y más del área de salud Vedado Androgen deficiency in men aged 60 or more from Vedado health area
Eduardo álvarez Seijas,Gilda Monteagudo Pea,Manuel Gómez Alzugaray,Celeste Arranz Calzado
Revista Cubana de Endocrinología , 2009,
Abstract: El declinar de la función testicular propia del envejecimiento ha adquirido relevancia en los últimos a os, sin embargo aún no se conoce su prevalencia, ni existe uniformidad para el diagnóstico. Se realizó un estudio descriptivo transversal con el objetivo de determinar la prevalencia y características clínico-hormonales del déficit androgénico en varones de 60 a os y más. Se incluyeron 70 sujetos de un área de salud, seleccionados mediante muestreo aleatorio estratificado polietápico, a los cuales se interrogó sobre la presencia de síntomas de deficiencia androgénica, se les realizó examen físico general y genital y determinaciones de testosterona total, hormona luteinizante y hormona folículo estimulante en sangre periférica. De acuerdo con las concentraciones de la testosterona se dividieron en 2 grupos: a) sujetos con deficiencia androgénica y b) sujetos sin deficiencia androgénica. Los que presentaron déficit androgénico tenían un peso significativamente superior, una proporción mayor de obesidad y una talla significativamente inferior. Los síntomas de déficit androgénico fueron frecuentes, los refirieron indistintamente los integrantes de ambos grupos y se presentaron independientemente de las concentraciones de las hormonas sexuales. En general, las gonadotropinas estaban aumentadas fundamentalmente a expensas de hormona folículo estimulante y su comportamiento fue independiente de las concentraciones de testosterona. Decline of testicular function typical of aging has acquired relevance in past years, however yet it is unknown its prevalence and there is not evenness for its diagnosis. A cross-sectional and descriptive study was made to determine the prevalence and clinical-hormonal features of androgen deficit in males aged 60 or more. Included are 70 subjects from a health area selected by multistage stratified randomized sampling that were interrogated about presence of androgen deficiency syndrome and underwent a physical and genital examination and total testosterone determinations, luteinizing hormone and follicle-stimulating hormone in peripheral blood. According the testosterone concentrations they were divided into two groups: a) subjects presenting with androgen deficiency and b) subjects without this type of deficiency. Those with androgen deficit had a higher weight, a higher obesity ratio, and a significantly lower height. The symptoms of androgen deficit were frequent, recounted indiscriminately by both groups and independently of sexual hormone concentrations. Generally, gonadotropins were increased mainly at the expense of folli
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