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Search Results: 1 - 10 of 205151 matches for " Alicia Martínez de Sandelices "
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Bases genéticas del síndrome de ovarios poliquísticos
Ovies Carballo,Gisel; Martínez de Sandelices,Alicia; Monteagudo Pe?a,Gilda; Sardi?as Díaz,Irelys;
Revista Cubana de Endocrinolog?-a , 2011,
Abstract: the syndrome of polycystic ovaries is the endocrine disorder involving more the reproductive sphere of the woman in fertile age, its causes are unknown with accuracy, but most of experts coincide in propose that it is a multifactor entity where the genetic factor more and more have a great significance. in past years, it has been possible to identify some genes involved in the pathogenic processes of this syndrome and among the more important are included those codifying for enzymes of the steroidogenesis, for the insulin receptor and other hormones related to the insulin action, as well as the gonadotropins and its receptors, features that are the aim of present review.
Bases genéticas del síndrome de ovarios poliquísticos Genetic bases of polycystic ovary syndrome
Gisel Ovies Carballo,Alicia Martínez de Sandelices,Gilda Monteagudo Pe?a,Irelys Sardi?as Díaz
Revista Cubana de Endocrinología , 2011,
Abstract: El síndrome de ovarios poliquísticos es el trastorno endocrino que más afecta la esfera reproductiva de la mujer en la edad fértil, sus causas se desconocen con exactitud, pero la mayoría de los expertos coinciden en plantear que es una entidad multifactorial, en la que los factores genéticos cada vez cobran mayor importancia. En los últimos a os se han identificado varios genes involucrados en los procesos patogénicos de este síndrome, y dentro de estos, los más importantes son aquellos que codifican para enzimas de la esteroidogénesis, para el receptor de insulina y otras hormonas relacionadas con la acción de la insulina, así como las gonadotropinas y sus receptores, aspectos sobre los cuales trata la siguiente revisión. The syndrome of polycystic ovaries is the endocrine disorder involving more the reproductive sphere of the woman in fertile age, its causes are unknown with accuracy, but most of experts coincide in propose that it is a multifactor entity where the genetic factor more and more have a great significance. In past years, it has been possible to identify some genes involved in the pathogenic processes of this syndrome and among the more important are included those codifying for enzymes of the steroidogenesis, for the insulin receptor and other hormones related to the insulin action, as well as the gonadotropins and its receptors, features that are the aim of present review.
ética y Biotecnología: más preguntas que respuestas
Cardozo de Martínez Carmen Alicia
Revista Colombiana de Biotecnología , 2008,
Abstract: La innovación y la tecnología son reconocidas actualmente como motores de desarrollo social, por ello la discusión no está en si son pertinentes o no pues esto es claro para la comunidad académica, la ciencia y la tecnología. Un país sin innovación, creatividad y transferencia tecnológica no puede articularse con el resto del planeta. Sin embargo, y a pesar de ser algo tan propio y obvio del desarrollo, la tecnología, la innovación y la transferencia tecnológica generan grandes conflictos morales que deben ser abordados y resueltos por la misma comunidad a través de un puente dialógico que articule el lenguaje científico con el lenguaje social.
Etica en investigación con animales: Una actitud responsable y respetuosa del investigador con rigor y calidad científica
Cardozo de Martínez,Carmen Alicia; de Osorio,Afife Mrad;
Revista Latinoamericana de Bioética , 2008,
Abstract: this article tries to promote a reflection conscientious on the use and taken care of the animal in investigation articulating so much the technical concepts as the ethical ones, involving daily languages for the present scientist like the quality, validity and scientific competitiveness and approaching some questions that surely many already will have been made on the matter.
Why is Mexico a country of overweight or obese children? Por qué México es un país de ni os con sobrepeso u obesidad?
Alicia de la Macorra,Castulina Ni?o Martínez
MediSur , 2011,
Abstract: Background:According to parameters released by the World Health Organization, children in Mexico show an alarming increase in overweight, obesity and related health problems. Objective: To identify the relationship between fruits, vegetables and water consumption; the amount of physical activity and body mass index. Methods: A descriptive study was conducted with primary school children in six cities in Mexico from 2006 to 2010. Each child’s weight and height were collected and a questionnaire was applied in order to measure the following variables: types of foods they eat and physical activity they perform. Results: There was low correlation between feeding and physical activity. Body mass index was highly dependant on physical activity and feeding style as to the performance of other activities while eating, and less dependant on food quality. Conclusions: A critical summary of findings suggesting ways of establishing good eating habits and physical activities inside and outside school hours as a way to influence the growth of normal body mass index was elaborated. Fundamento: de acuerdo con los índices de la Organización Mundial de la Salud, la ni ez de México muestra un alarmante incremento del sobrepeso y la obesidad, con problemas de salud asociados. Objetivo: identificar la relación entre el consumo de fruta, verdura, agua, el grado de actividad física y el índice de masa corporal. Métodos: estudio descriptivo realizado en aulas de ni os de primaria de seis ciudades de México, desde 2006 a 2010. Se midió peso y talla; se aplicó un cuestionario con las siguientes variables a medir: tipos de alimentos que ingieren, actividad física que realizan. Resultados: existió baja correlación entre las variables alimentación y actividad física; alta dependencia del índice de masa corporal de las variables actividad corporal y modo de alimentarse (realizar otra actividad mientras se come), más que de la calidad de los alimentos. Conclusiones: se elaboró un resumen crítico de hallazgos y formas que se sugieren para establecer buenos hábitos de alimentación y ejercicio físico dentro y fuera del horario escolar, como manera de incidir en el crecimiento del índice de masa corporal normal.
One cell test para el estudio in vitro de citotoxicidad del extracto de una planta de la flora colombiana Cytotoxicity in vitro study of the extract of a Colombian flora
Saúl Daniel,Mrad de Osorio Afife,Martínez Constanza,Cardozo de Martínez Carmen Alicia
Revista Colombiana de Biotecnología , 2004,
Abstract: Este estudio se realizó con el fin de evaluar la toxicidad del extracto de Abuta grandifolia mediante la técnica de One cell test. El extracto etanólico se preparó mediante secado y pulverización del tallo de la A. grandifolia; la extracción se realizó con etanol al 96% y posterior-mente se hizo una extracción ácido-base hasta obtener la fracción alcaloidal purificada. Los resultados revelaron que el extracto inhibió el crecimiento celular de modo dosis-dependiente en concentraciones de 0.01, 0.02, 0.1 y 0.4% en medio HTF. Palabras clave: One cell test, citotoxicidad, alternativas, embrión. This study was aimed at evaluating Abuta grandifolia plant extract toxicity using the One cell test. The ethanol extract was prepared by drying and grinding up A. grandifoliastems. Extraction was done with 96% ethanol, followed by further acid-base extraction to obtain a purif ied alcaloidal f raction. The results showed extract dose-dependent cell growth inhibition at concentrations ranging f rom 0.01 %, 0.02%, 0.1 % to 0.4% in HTF medium. Key words: One cell test, cytotoxicity, alternatives, embryo.
Aproximación al cultivo de condrocitos en la Universidad Nacional de Colombia.: Reporte técnico
Landínez Parra,Nancy Stella; Garzón Alvarado,Diego Alexander; Cardozo de Martínez,Carmen Alicia;
Revista Cubana de Investigaciones Biom??dicas , 2010,
Abstract: the loss of a tissue or its function due to congenital defects, disease or trauma, is one of the major, frequent and expensive problems challenging the human medicine. the articular cartilage degeneration is known as osteoarthritis (oa), which is characterized by enzyme and mechanical damage of extracellular matrix, generating pain and lead to the loss of movement and articular instability. the articular cartilage has low repair ability due to its avascularization. the aim of present paper is to make an approach to cartilage tissue engineering to establish the theoretical basis on this subject to understand the tissue in vitro behavior allowing in the future, to construct a cartilage equivalent by means of current procedures of tissue engineering, offering a response to social problems and of the public health. conclusions from present paper make easy futures researches in the field of articular cartilage regeneration and its clinical application and also, providing the bases to planning in vivo and in vitro researches to deepen in this subject.
Aproximación al cultivo de condrocitos en la Universidad Nacional de Colombia.: Reporte técnico Approach to chondrocytes culture in National University of Colombia.: A technical report
Nancy Stella Landínez Parra,Diego Alexander Garzón Alvarado,Carmen Alicia Cardozo de Martínez
Revista Cubana de Investigaciones Biom??dicas , 2010,
Abstract: La pérdida de un tejido o de su función, debido a defectos congénitos, enfermedad o trauma, es uno de los problemas más difíciles, frecuentes y costosos que enfrenta la medicina humana. La degeneración del cartílago articular se conoce como osteoartrosis (OA), la cual se manifiesta mediante da o enzimático y mecánico de la matriz extracelular, que genera dolor y conduce a pérdida del movimiento e inestabilidad articular. El cartílago articular tiene una baja capacidad de reparación, por su avascularidad. El presente trabajo pretende realizar una aproximación a la ingeniería tisular del cartílago con el propósito de establecer la fundamentación teórica en el tema para comprender el comportamiento in vitro del tejido que permita a futuro construir un equivalente de cartílago mediante los procedimientos actuales de ingeniería tisular, que ofrezca respuesta a la problemática social y de salud pública. Las conclusiones del presente trabajo posibilitan futuras investigaciones en el campo de la regeneración de cartílago articular y su aplicación clínica e igualmente brindan las bases para plantear investigaciones in vivo o in vitro que profundicen en el tema. The loss of a tissue or its function due to congenital defects, disease or trauma, is one of the major, frequent and expensive problems challenging the human medicine. The articular cartilage degeneration is known as osteoarthritis (OA), which is characterized by enzyme and mechanical damage of extracellular matrix, generating pain and lead to the loss of movement and articular instability. The articular cartilage has low repair ability due to its avascularization. The aim of present paper is to make an approach to cartilage tissue engineering to establish the theoretical basis on this subject to understand the tissue in vitro behavior allowing in the future, to construct a cartilage equivalent by means of current procedures of tissue engineering, offering a response to social problems and of the public health. Conclusions from present paper make easy futures researches in the field of articular cartilage regeneration and its clinical application and also, providing the bases to planning in vivo and in vitro researches to deepen in this subject.
The future of environmental health in Andalusian Region: suitability of improvement El futuro de la sanidad ambiental en Andalucía: oportunidades de mejora
José Antonio Ferreras Iglesias,Joaquín Jesús Gámez de la Hoz,Alicia Martínez Martínez
Revista de Salud Ambiental , 2008,
Abstract: In the present article is presented a portrait of the situation of the environmental health in the administration of Andalusian Goverment; are analyzed implanted management formulations and we believe a reflection space on the professional exercise and the course begun with the organizational process in the Andalusian public health. The public health system has not undergone reconstruction from the process of transferences from the State towards the autonomous Communities. We identified the extrapolation of the model clinical-assistance management to the public health structures without delving what is sufficient in their organization and objectives. Setting of business process management (BMP) has got worse the administrative bureaucracy and the teamwork has not been preceded of alliances and agreements that generate feeling of ownership the same organization to avoid professional conflicts. We bet on strengthening the paper of the environmental health technicians as referring in the identification of this performances within public health system. For this propose we need the implication of all the professionals in the reform of the organization and management of the health public, to evolve in the professional exercise creating a regulated academic specialty and to define the competences maps in their different capabilites areas. En el presente artículo se muestra un retrato de la situación de la sanidad ambiental en la Administración de la Junta de Andalucía; se analizan las fórmulas de gestión implantadas y creamos un espacio de reflexión sobre el ejercicio profesional y el rumbo iniciado con el proceso organizativo en la salud pública andaluza. La Salud Pública no ha sufrido reestructuración desde el proceso de transferencias desde el Estado hacia las comunidades autónomas. Identificamos la extrapolación del modelo de gestión clínico-asistencial a las estructuras de salud pública sin ahondar lo suficiente en su organización y objetivos. La puesta en práctica de la gestión por procesos ha agudizado la burocracia administrativa y el trabajo en equipo no ha estado precedido de alianzas y pactos que generen un sentimiento de pertenencia a la misma organización evitando conflictos profesionales. Apostamos por fortalecer el papel de los técnicos de sanidad ambiental como referentes en la identificación de las prestaciones de salud ambiental dentro del sistema sanitario público. Para ello proponemos la implicación de todos los profesionales en la reforma de la organización y gestión de la salud pública, evolucionar en el ejercicio profesional creando una
Sodio urinario como marcador bioquímico de la ingesta estimada de sal en ni?os y adolescentes
Maskin de Jensen,Alicia Noemí; López,Miryan Susana; Mir,Claudia Nora; Martínez,Pedro;
Acta bioqu?-mica cl?-nica latinoamericana , 2011,
Abstract: the aim of this study was to evaluate the estimated salt intake in "clinically healthy" children and adolescents, using the 24 h sodium urinary excretion as biochemical marker or indicator. a hundred and twelve male and female children aged 5 to 15, without a dietary restriction who visited the province pediatric hospital - posadas were evaluated. urinary sodium in 24 hours was measured using the electrode selective ion method. the salt intake (g/day) was calculated as: urinary sodium (mmol/day) x 58.5. there were no significant differences in estimated salt intake by gender. children aged from 9 to 15 have a significantly higher (p< 0.05) consumption (2.5 to 17 g salt /day) than those between the ages of 5 to 8 (1.3 a 11.7 g salt/day). a 24% of the children aged 5 to 8 and only a 15% at the age range 9 to 15 consume according international recommendations. the daily estimated salt intake indicates that a great percentage of the population studied presents a usual high consumption of salt, greater than their physiological needs and the recommended aims for prevention hypertension.
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