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Search Results: 1 - 10 of 18490 matches for " Ali Thwaini "
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Vesico-vaginal fistula post cold cup bladder biopsy: mini review
Abigail Mawhinney, Ammar Hameed, Ali Thwaini, et al
Research and Reports in Urology , 2010, DOI: http://dx.doi.org/10.2147/RRU.S12181
Abstract: ico-vaginal fistula post cold cup bladder biopsy: mini review Case report (4072) Total Article Views Authors: Abigail Mawhinney, Ammar Hameed, Ali Thwaini, et al Published Date September 2010 Volume 2010:2 Pages 171 - 175 DOI: http://dx.doi.org/10.2147/RRU.S12181 Abigail Mawhinney1,*, Ammar Hameed2,*, Ali Thwaini1, Colin Mulholland1 1Belfast City Hospital, Urology Department, Belfast, Northern Ireland, UK; 2Addenbrookes University Hospital, Urology Department, Cambridge, UK *These authors contributed equally to this paper Introduction: We report a case of a vesico-vaginal fistula (VVF) post cold cup biopsy; to our knowledge this is the only reported case. We present the clinical history/presentation, investigation and the outcome of the treatment. VVFs are among the most distressing complications of gynecologic and obstetric procedures. The risk of developing a VVF is more than 1% after radical surgery and radiotherapy for malignancies. Management of these fistulas has been better defined and standardized over the last decade. Methods and results: A case of low grade superficial bladder cancer was treated with multiple resections of bladder tumor and a single installation of mitomycin post initial resection which successfully cleared her bladder cancer, but nevertheless led to a small size and scarred bladder. In addition there was a long history of smoking with its effects on tissue integrity and healing. VVFs are very rare and are an unpleasant outcome post a cold cup biopsy, adding to the psychological and social effects of the surgical treatment. Conclusion: Although cold cup biopsy is a normal day procedure performed by both residents and consultants, consensus should exist on how to treat a patient who has a bladder with defective integrity and small capacity. The rate of successful fistula repair reported in the literature varies between 70% and 100% in nonradiated patients, with similar results when a vaginal or abdominal approach is performed, the mean success rates being 91% and 97%, respectively.
Vesico-vaginal fistula post cold cup bladder biopsy: mini review
Abigail Mawhinney,Ammar Hameed,Ali Thwaini,et al
Open Access Journal of Urology , 2010,
Abstract: Abigail Mawhinney1,*, Ammar Hameed2,*, Ali Thwaini1, Colin Mulholland11Belfast City Hospital, Urology Department, Belfast, Northern Ireland, UK; 2Addenbrookes University Hospital, Urology Department, Cambridge, UK*These authors contributed equally to this paperIntroduction: We report a case of a vesico-vaginal fistula (VVF) post cold cup biopsy; to our knowledge this is the only reported case. We present the clinical history/presentation, investigation and the outcome of the treatment. VVFs are among the most distressing complications of gynecologic and obstetric procedures. The risk of developing a VVF is more than 1% after radical surgery and radiotherapy for malignancies. Management of these fistulas has been better defined and standardized over the last decade.Methods and results: A case of low grade superficial bladder cancer was treated with multiple resections of bladder tumor and a single installation of mitomycin post initial resection which successfully cleared her bladder cancer, but nevertheless led to a small size and scarred bladder. In addition there was a long history of smoking with its effects on tissue integrity and healing. VVFs are very rare and are an unpleasant outcome post a cold cup biopsy, adding to the psychological and social effects of the surgical treatment.Conclusion: Although cold cup biopsy is a normal day procedure performed by both residents and consultants, consensus should exist on how to treat a patient who has a bladder with defective integrity and small capacity. The rate of successful fistula repair reported in the literature varies between 70% and 100% in nonradiated patients, with similar results when a vaginal or abdominal approach is performed, the mean success rates being 91% and 97%, respectively.Keywords: vesico-vaginal fistula, vaginal fistula, surgical repair of vaginal fistula, management of vaginal fistula
Outcome of Glansectomy and Skin Grafting in the Management of Penile Cancer
Hugh F. O'Kane,Ajay Pahuja,K. J. Ho,Ali Thwaini,Thaigarajan Nambirajan,Patrick Keane
Advances in Urology , 2011, DOI: 10.1155/2011/240824
Abstract: Purpose. To report outcome data for patients with penile cancer treated surgically with glansectomy and skin grafting. Materials and Methods. We retrospectively reviewed data on all patients undergoing surgical management of penile cancer by a single surgeon between 1998 and 2008. Outcomes in patients who underwent glansectomy and skin grafting were analysed. Results. Between 1998 and 2008 a total of 25 patients with a mean age 60 (39–83) underwent glansectomy and skin grafting. Six patients had carcinoma in situ (CIS); the stage in the remaining patients ranged from T1G1 to T3G3. Mean followup for patients was 28 months (range 6–66). Disease specific survival was 92% with 2 patients who had positive nodes at lymph node dissection developing groin recurrence. One patient developed a local recurrence requiring a partial penectomy. Conclusions. Penile preserving surgery with glansectomy and skin grafting is a successful technique with minimal complications for local control of penile carcinoma arising on the glans. Careful followup to exclude local recurrence is required. 1. Introduction Penile cancer is an uncommon malignancy in the industrialized world, particularly in Europe and in the USA with an incidence of less than 1 per 100?000 of the male adult population. In contrast to this, the incidence in some parts of the developing world is as high as 19 per 100?000 per year [1]. More than 95% of penile cancers are primary squamous cell carcinomas with other uncommon histological types including melanoma, sarcoma, and basal cell carcinomas. Historically, the surgical management of the primary lesion in penile carcinoma has meant either partial or radical penectomy. Oncologically, radical surgical excision has stood the test of time, with excellent local control. These operations are however often mutilating and associated with urinary and sexual dysfunction as well as significant psychological morbidity [2]. In an attempt to reduce the negative impact of radical surgery and retain functional penile length, a variety of therapeutic strategies have been developed particularly for the management of more distal lower-grade cancers. The obvious risk is always that there will be compromise of local oncological control. Oncological outcomes of “penile preserving” surgical techniques should always, if possible, be measured against the gold standard of radical excision. Randomised trials are next to impossible in such an uncommon disease and although widely practiced and results are encouraging, only a small number of centres have published their outcome data on
Severe Intraperitoneal Haemorrhage following Suprapubic Catheter Insertion in a Patient Treated with Iloprost
R. A. J. Spence,A. Thwaini,Aidan O’Brien
Case Reports in Urology , 2013, DOI: 10.1155/2013/724685
Abstract: Suprapubic catheter (SPC) insertion is a common urological procedure, performed both in the elective and emergency settings. The authors present an unusual case of severe intraperitoneal bleeding following the insertion of an SPC under direct vision, where the use of prostacyclin analogue may have been a contributing factor. 1. Introduction Prostacyclin analogue (Iloprost) is used in a variety of clinical conditions, for example, pulmonary hypertension and Raynaud’s phenomenon. We report a case of a 42-year-old female who had an elective insertion of SPC. She had an intravenous infusion of Iloprost earlier that day. Following catheter insertion, she developed severe postoperative bleeding requiring laparotomy. To our knowledge this is the first case reported in the literature with a complication related to prostacyclin infusion. 2. Case Report A 42-year-old female patient with advanced multiple sclerosis (MS) for the last 13 years was admitted electively under the medical team with a new diagnosis of Reynaud’s phenomenon. During her admission she expressed an interest in having an SPC inserted instead of her long term urethral catheter. She had been recently commenced on daily intravenous infusion of prostacyclin analogue (Iloprost) to treat her Reynaud’s phenomenon. After counselling, the patient was booked for cystoscopy (under general anaesthesia) and SPC insertion. She had finished her fifth day of iloprost at 12?pm. She had her procedure performed at 4?pm with no intraoperative issues. Three hours later, whilst back on the ward, the patient developed severe generalised abdominal pain and became unstable with hypotension and tachycardia. Her haemoglobin dropped from 12?gm/L to 8?gm/L. She was stabilised with intravenous plasma expanders and packed red blood cells. An emergency computed tomography (CT) scan confirmed intraabdominal bleeding (Figure 1). Figure 1: CT scan demonstrating significant intraperitoneal bleeding. She was immediately taken to the theatre for an emergency laparotomy. There was approximately 3 litres of blood within her abdomen, with intra-peritoneal blood clots visible. The catheter was found to be in the urinary bladde, but had followed an intraperitoneal path, with a small haematoma on the peritoneal surface of the bladder. No active bleeding was found, and it was assumed that the bleeding was from the dome of the bladder. She recovered well from the operation and was discharged in a good health. 3. Discussion Insertion of SPC is a common procedure in urology. Despite the fact that this procedure is relatively safe, it is not
Primary Plasmacytoma of the Kidney
R. A. J. Spence,A. Thwaini,D. M. O'Rourke
Case Reports in Urology , 2013, DOI: 10.1155/2013/239580
Abstract: Primary renal plasmacytomas are an extremely rare clinical condition. Their management is particularly challenging due to the paucity of evidence, with only just over a dozen previously reported cases. We report a case of a primary extramedullary plasmacytoma of the kidney and performed a review of the literature. The case is presented as a learning point that it is imperative to keep plasmacytic tumours in mind and to include them in the differential diagnosis of anaplastic tumours, even in unusual locations, such as the kidney. 1. Introduction Plasmacytomas are malignant plasma cell tumours which are characterised by the proliferation of a single clone of plasma cells, producing monoclonal immunoglobulins. They may arise in soft tissue (extramedullary), or within the skeleton [1]. Skeletal plasmacytomas are the most common primary, with extramedullary plasmacytomas typically arising from fat, muscle, or mucosal surfaces; common sites include respiratory and digestives tracts, head and neck regions, with more than 80% situated above the diaphragm [2, 3]. Extramedullary plasmacytomas typically affect patients during middle age (median 55–60 years) and are more common in males (Male?:?Female 3?:?1) [4]. Confirmed risk factors for plasmacytomas remain unknown; however, prior radiation exposure has been suggested [5]. 2. Case Report A 49-year-old male presented with a two-day history of sudden, severe, right sided loin pain which was associated with vomiting. There was no history of any prior lower urinary tract symptoms. Past medical history included squamous cell carcinoma of the tongue for which the patient underwent partial excision and adjuvant radiotherapy and had no evidence of recurrence. Haematological investigations revealed deranged renal function with significantly raised serum creatinine. C-reactive protein was also elevated. (Computed tomography) CT and (magnetic resonance) MR imaging demonstrated a solid lesion involving the lower two thirds of the right kidney (Figures 1 and 2). The left kidney was atrophic. The patient was initially managed with right JJ stenting, which resulted in normalisation of his creatinine. However, renal function began further deterioration, thus underwent right percutaneous nephrostomy tube insertion. Renal function normalised following this procedure. Figure 1: Axial CT image demonstrating primary plasmacytoma of the kidney. Figure 2: Coronal CT image demonstrating primary plasmacytoma of the kidney. As imaging demonstrated that this lesion was atypical, a renal biopsy was performed. Results were highly
Microbiological Study on Male Urethritis
N.G. Khalil,A.M. Ghazal,A.J. Thwaini
Pakistan Journal of Biological Sciences , 2003,
Abstract: C. trachomatis is found in 37% of patients with urethritis. It is found either concurrently with N. gonorrhoeae or alone in case of NGU. Other organisms were also isolated from the urethral discharge of patients. History of trachoma does not affect the rate of infection with chlamydia.
Ultrastructural Identification of the Basal-Granulated Cells in the Duodenum of Albino Rat  [PDF]
Ali Hassan A. Ali
Open Journal of Gastroenterology (OJGas) , 2014, DOI: 10.4236/ojgas.2014.47041
Abstract: The fine structure of the crypt epithelium of the duodenal mucosa in albino rats was studied to represent the types and distribution of the basal-granulated or endocrine cells. Twenty male animals were used. Perfusion-fixation was made and samples of duodenal mucosa were taken and processed to prepare epon-embedded specimens for examination by a transmission electron microscope. Cells containing membrane-bound granules were seen in the crypt epithelium. They were identified to be basal-granulated cells. Six different types of such cells were demonstrated. All of the cells were of the closed type. The possible functional significance of these closed cell types was discussed. Correlation among the distributions of such cells in the intestine of albino rat might enable the physiologists, internists and other research workers to study several biologically active peptides with well-established functions other than those which have long been investigated.
Hepatoprotective Effect of Green Tea Extract against Cyclophosphamide Induced Liver Injury in Albino Rats  [PDF]
Ali Hassan A. Ali
Forensic Medicine and Anatomy Research (FMAR) , 2018, DOI: 10.4236/fmar.2018.62002
Abstract: Background: Green tea intake is accompanied with a lower incidence of cardiovascular disease, cancer and neurodegenerative disorders; hence green tea extract has been included as dietary supplement along with other supplements and multivitamins. Aim of the Work: Studying the effect of cyclophosphamide administration on the liver of adult male albino rats and the possible protective role of green tea extract. Material and Methods: The current study was carried out on 45 adult male albino rats. They were divided into three equal groups (each included 15 rats). Group I (control group) was injected intraperitoneally with normal saline at a dosage of 0.5 mg/kg body weight twice weekly for 9 weeks. Group II was injected intraperitoneally with cyclophosphamide (CP) (150 mg/kg/day) for two weeks. Group III: rats received green tea extracts orally (50 mg/kg/day) for three weeks, and then continued for further two weeks concomitantly with intraperitoneally cyclophosphamide (CP) injected (150 mg/kg/day). Results: Rats exposed to cyclophosphamide (CP) showed several histological and histochemical changes in their liver. These changes were improved by using green tea. Conclusion: The present work showed that green tea had preventive and therapeutic effect upon livers of albino rats after they were exposed to CP.
A Primal-Dual Simplex Algorithm for Solving Linear Programming Problems with Symmetric Trapezoidal Fuzzy Numbers  [PDF]
Ali Ebrahimnejad
Applied Mathematics (AM) , 2011, DOI: 10.4236/am.2011.26089
Abstract: Two existing methods for solving a class of fuzzy linear programming (FLP) problems involving symmetric trapezoidal fuzzy numbers without converting them to crisp linear programming problems are the fuzzy primal simplex method proposed by Ganesan and Veeramani [1] and the fuzzy dual simplex method proposed by Ebrahimnejad and Nasseri [2]. The former method is not applicable when a primal basic feasible solution is not easily at hand and the later method needs to an initial dual basic feasible solution. In this paper, we develop a novel approach namely the primal-dual simplex algorithm to overcome mentioned shortcomings. A numerical example is given to illustrate the proposed approach.
Application of Linear Model Predictive Control and Input-Output Linearization to Constrained Control of 3D Cable Robots  [PDF]
Ali Ghasemi
Modern Mechanical Engineering (MME) , 2011, DOI: 10.4236/mme.2011.12009
Abstract: Cable robots are structurally the same as parallel robots but with the basic difference that cables can only pull the platform and cannot push it. This feature makes control of cable robots a lot more challenging compared to parallel robots. This paper introduces a controller for cable robots under force constraint. The controller is based on input-output linearization and linear model predictive control. Performance of input-output linearizing (IOL) controllers suffers due to constraints on input and output variables. This problem is successfully tackled by augmenting IOL controllers with linear model predictive controller (LMPC). The effecttiveness of the proposed method is illustrated by numerical simulation.
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