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Search Results: 1 - 10 of 18599 matches for " Ali Shahriari "
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Complete separation of the tube from the mask of a reusable classic laryngeal mask airway: a case report
Ali Shahriari
Journal of Research in Medical Sciences , 2007,
Abstract: The laryngeal mask airway (LMA) is an important addition to the anesthetist's equipments. However, its usage may involve some complications. We have encountered an unusual and potentially serious complication using this equipment. A 45-year old man underwent cataract surgery under general anesthesia. After the induction of anesthesia, a size 4 of the reusable classic LMA was inserted without any difficulties and the cuff was inflated. After a little manipulation, the proximal tube of the LMA was separated from the distal part, leaving the distal mask inside the pharynx. The exit of the remaining portion of the LMA was very difficult and made the ventilation of the patient impossible. The patient’s oxygen saturation decreased to 40%. The remaining portion of the LMA was removed by a great clamp and with an extreme effort. Then, an endotracheal tube was inserted and the patient was ventilated with 100% oxygen. After 6 hours, the patient was discharged with no apparent complications. The autoclave was used several times for the sterilization of the LMA. KEY WORDS: Laryngeal mask airway, autoclave.
Comparison of Midazolam with Lidocaine and Fentanyl for Caudal Analgesia in Children
Shahriari Ali,Khooshideh Maryam
Journal of Medical Sciences , 2007,
Abstract: To compare postoperative analgesia provided by caudal administration of midazolam and mixture of lidocaine and fentanyl in children, in a randomized, double-blind study, forty children, undergoing hypospadia repair were allocated randomly into two groups (n = 20 in each) to receive a caudal injection of either lidoacaine 4 mg kg-1 added with fentanyl 1 μg kg-1 and epinephrine 1/200000 or midazolam 50 μg kg-1, each solution diluted with normal saline for reaching a volume of 1 mL kg-1. There were no differences in quality of pain relief, postoperative behaviour or analgesic requirements between the midazolam group and the lidoacaine group. Times to first analgesic administration (paracetamol suppositories) were similar in two groups. Caudal midazolam in a dose of 50 μg kg-1 and in a volume of 1 mL kg-1 provides equivalent analgesia to 4 mg kg-1 lidoacaine added to fentanyl and epinephrine, when administered postoperatively for children following hypospadia repair.
Comparison of successful intubation with two different blades of laryngoscope: single-use and reusable.
Ali Shahriari,Maryam Khooshideh,Hassan Enayaty
Journal of Research in Medical Sciences , 2007,
Abstract: BACKGROUND: Many types of single-use blades are manufactured with different designs and materials. There have been several reports of difficulties in obtaining a view of the glottis with single-use laryngoscopes. The purpose of this prospective study was to compare the quickness and the success rate of endotracheal intubations with two different laryngoscope blades: disposable laryngoscope blades and reusable laryngoscope blades. METHODS: The study included 200 patients aged 18 to 70 who were admitted to the operating room of the Ali Ebne Abitaleb Hospital in Zahedan. The patients were randomly divided in two groups. Disposable laryngoscope blades were used for the first group and reusable laryngoscope blades were used for the second group. The endotracheal intubation duration and the failure rate of the intubation were assessed in the two groups. RESULTS: No failures and prolongations of intubations were found in the reusable laryngoscope blades group compared with 21% incidence of prolonged intubations and 14% incidence of failed intubations in the prolonged intubations group which led to change of the laryngoscope by the anesthetists (P<0.05). CONCLUSIONS: The single-use laryngoscope blades appear to be efficient devices because they do not modify the ease of endotracheal intubation in most cases. Nonetheless, for difficult intubations it is advised to maintain conventional laryngoscopes in reserve.
Triple-Negative Breast Cancer: Clinical Characteristics, Prognostic Features, and Long-Term Outcome: A Comparative Study
Leila Rahmani,Ali Shahriari Ahmadi,Ali Basi,Tahere Zarouk Ahimahalle
International Journal of Hematology-Oncology and Stem Cell Research , 2012,
Abstract: Background: Because of the reported poor prognosis and absence of effective and specific therapeutic approaches, triple-negative breast cancer (TNBC) tumors have remained as an important area of investigations for clinicians and researchers. The aim of this study was to determine the clinical, pathological, histological, prognostic features, and outcome associated with this type of breast cancer in Iran. We also tried to identify main determinants of long-term survival in women suffered from TNBC tumor type. Methods: This is a historical cohort study of 546 consecutive female breast cancer patients with known status of hormonal receptors and diagnosed at the Rasoul-e-Akram University Hospital of Iran between January 2009 and June 2011. Baseline data were collected from patient records and hospital charts. Long-term outcome was determined from clinic records when available or by means of written correspondence with patients' physicians and telephone interviews directly with the patients or with family members. Follow-up data were collected by our research personnel for a mean follow-up duration 5.7 years. Results: A total of 86 of 546 final included participants with breast cancer were identified as having TNBC (15.8%).The patients with TNBC diagnosis were significantly younger than non-TNBC group and family history of breast cancer was more prevalent in former group. Regarding histopathological feature, medullary feature was more prevalent in TNBC group, while other features were similarly revealed in both groups. With respect to tumor grading, TNBC group was graded higher than non-TNBC group that grade III of tumor was reported in 51.1% of the TNBC patients, but in 15.9% of another group. Also, the stage of tumor was significantly higher in the TNBC group. Tumor size > 50 mm was observed in 18.6% of the TNBC and 14.8% of non-TNBC groups. Metastasis to liver as well as concurrent metastasis to brain and pulmonary was more prevalent in TNBC compared with another group. The Kaplan-Meier curves based showed the survival probability at 1-year, 3-year, and 5-year of follow-up in TNBC group was 92.7%, 86.2%, and 44.9%, respectively. This survival rates in non-TNBC group was 98.7%, 87/2%, and 72.5%, respectively. Multivariable logistic regression analysis showed that TNBC diagnosis could strongly predict long-term mortality in breast cancer patients. Besides, tumor size, number of involved lymph nodes and higher tumor grade were other determinants of cancer-related long-term mortality. Conclusion: The present study on Iranian TNBCs population shows that TNBCs
The Association between Prevalence of JAK2V617F Mutation and Blood Indicies in Groups of Patients with Myeloproliferative Neoplasms in Rasul Akram Hospital
Akram Asghari,Ali Shahriari Ahmadi,Ali Basi,Masood Vkili
International Journal of Hematology-Oncology and Stem Cell Research , 2011,
Abstract: Introduction: Myeloproliferative neoplasms (MPNs) are a group of clonal malignant hematologic disease, where the main and common members are; polycythemia vera (PV), primary myelofibrosis (PMF), and essential thrombocytosis (ET). These group of diseases are able to be transformed into each other. Methods: This cross sectional study conducted the evaluation of JAK2V161F mutation in DNA in peripheral blood of 91 patients with known or suspected diagnosis of MPNs by Real time PCR method and survey of peripheral blood smear. Result:. Prevalence of JAK2V617F mutation between patients was %58.2 and PV had most common prevalence ratio between other groups. While mean age of patients was 50/9 yr (for 39.6% male and 60.4% female), three patients (equal of %3.3) were atypical presentation and 2 patients die due to malignant transformation. There were significant differences in age, WBC and PLT (in PV) with prevalence of JAK2V617F mutation. These differences were not significant in other group. Discussion: Current study showed a high rate of association between JAK2V617F mutation in patients with PV, ET, PMF in Iranian patients. Therefore, Peripheral blood mutation screening for JAK2 V617F can be incorporated into the initial evaluation of patients suspected to have chronic myeloproliferative neoplasm and used of this test for determining of association between JAK2V617F mutation, treatment of patients with blood indexes and patients of prognosis.
Iranian Cancer Network: Introduction, Mission and Its Role in Cancer Management
Kamran Alimoghaddam,Forough Foroughi,Ali Shahriari Ahmadi,Vahid Farnia
International Journal of Hematology-Oncology and Stem Cell Research , 2005,
Abstract: Objectives: The Iranian Cancer Network was established in May 2003. Our aim was to coordinate re search and treatment programs in all cancer centers in Iran in order to save time and money and enable patients, wherever they live, to receive a uniformly high-standard treatment and care. Methods: After signing a mutual contract with fellow (collaborator) university and holding some shared sessions, the project was planned on the basis of the network missions. Network structure guide lines and the responsibility of the sections and staff in the network were being defined. Cancer teams include physicians, epidemiologists, pathologists, basic scientists, and executive authorities related to cancer management."nResults: The Iranian Cancer Network has started its work as a preliminary study between two centers. Then some other cancer centers in the country joined it and it is developing gradually. Several common research projects and clinical trials have been started in this network. Genomic DNA bank for patients with hematopoetic malignancies is being constructed. Data bank for all cancers referring to these cen ters is being constructed and its result will be published later."nConclusion: Cancer networks make a systematic connection between all cancer centers around a coun try (or abroad) to ensure delivery of new information, interventions, and best practices and help others to share their research and laboratory facilities.
Left Ventricular Diastolic and Systolic Performance: A Study Using Tei Index in Adulthood Patients with Thalassemia Major
Mitra Kazemi Jahromi,Ali Shahriari Ahmadi,Kaveh Mousavi Kani
International Journal of Hematology-Oncology and Stem Cell Research , 2011,
Abstract: Introduction: Cardiac complications, including heart failure, are the most important secondary ones of the thalassemia major disease, which manifests itself in adolescence and early adulthood. Appropriate, low cost diagnostic tools available as well as knowing its related factors are the most important components of therapy in these patients, given the importance of these complications, or by examining and revealing early symptoms. Thus, in this study, we intend to examine the systolic and diastolic ventricular effects in adult patients with the help of Tei index. Methods: 70 adult patients with thalassemia major were examined in this study. Frequency of Tei index and its association with factors such as age, sex, level of packed cell injection, as well as hemosiderosis were measured in two blood levels of more than 1000 ferretins. Results: In this study, 70 youth adult patients with thalassemia major with an average age of 21.3± 2.8 years were studied, 31 were male (44.4%). Tei index were abnormal in 16 patients (24%). There is no statistically significant correlation between the Tei index and one of the variables of age, gender, number and duration of blood transfusion and deferoxamine, the hemoglobin level and the number of ferretins (P>0.05). Discussion: Study on Tei index shows that many patients are subclinically involved in the disease before the onset of clinical symptoms of heart failure, the subject which raises the need for early diagnosis of the disease; and it seems that none of the demographic factors or factors related to disease cannot be considered as a main cause or warning of the disease; and the above results can be confirmed only on the basis of paraclinical tests.
Clinical Comparison of the Effects of Gabapentin and Megestrol Aacetate on Hot Flashes in Patients with Breast Cancer
Tahere Zarouk Ahimahalle,Ali Shahriari Ahmadi,Mohsen Arabi,Leila Rahmani
International Journal of Hematology-Oncology and Stem Cell Research , 2012,
Abstract: Introduction: Hot flash affects approximately 75% of women with breast cancer. Those who experience hot flashes have higher rates of sleep disorders, temper and lower quality of life than women with no hot flashes. The persent study was aimed to compare the effect of megestrol acetate with gabapentin on the severity of hot flashes in patients with breast cancer Materials and Methods: In a randomized controlled clinical-trial study 120 patient with breast cancer who had moderate and severe hot flashes were randomly assiged into two groups; 40 mg megestrol acetate twice daily and 300mg gabapentin oncedaily for a period of 8 weeks. Demographic data and the severity of hot flashes were recorded before treatment and 8 weeks after therapy. The obtained data was analysed using SPSS V15 withstatistical tests chi-square, Student T- Test and Paired T-Tes. Results: After 8 weeks of treatment with megestrol acetat a reduction of 64.3% in hot flash frequency and 37.1% reduction in hot flash severity from base line were observed. In the gabapentin group the decrease was 44.8% and 24.6% compared before treatment respectively.(P=0.005 , P=0.04 ) After eight weeks of treatment the number of hot flashes was 3.9±4.0 and 5.8±3.7 in the megestrol acetat and gabapentin groups respectively; the difference was statistically significant(P=0.04).In the megestrol acetat group number of hot flashes was obviously lower than their level in the gabapentin group. After eight weeks of treatment,the serverity of hot flashes was 50.4% and 62.9% in the megestrol and gabapentin groups respectively; the difference was statistically significant (P=0.005 ).In the megestrol group severity of hot flash was obviously lower than their levels in the gabapentin group.In the megestrol group frequency and severity of hot flashes were obviously significantly lower than their levels in the gabapentin group. Conclusion: Megestrol acetat is significantly more effective than the Gabapentin in treating hot flash and can be considered as an effective therapy to reduce the disorder.
Major Beta-thalassemia: Protective or predisposing Factor for Cardiovascular Diseases
Mitra Kazemi Jahromi,Ali Shahriari Ahmadi,Kaveh Mousavi kani
International Journal of Hematology-Oncology and Stem Cell Research , 2011,
Abstract: Introduction: Cardiac dysfunctions have been well known in patients with Major thalassemia. Some studies have focused on differences in blood pressure and heart rate between these patients and normal population, while this view has not been proven in other studies. Given the importance of hemodynamic factors in the health of these individuals, we intend to test the hypothesis as to whether or not hemodynamic factors of these patients differ from normal subjects.Methods: Patients were selected from among the thalassemic patients referred to a blood clinic of one of the third-level hospitals in Tehran. Finally, 50 patients and 50 normal subjects were studied in two groups. All subjects have been assessed using Holter monitoring. Mean average systolic blood pressure and heart rate of subjects were recorded for a period of 24 hours.In addition, demographic data on the subjects, and some laboratory tests (such as serum lipid profile and glucose levels of the patients) were also determined and compared between the two groups.Results: 100 people were evaluated in two groups, including 50 patients with thalassemia major and 50 normal subjects, matched by age and gender. The mean age of the subjects was 16.3 ± 6.7 years; and there is no significant difference in mean age of both groups.23 female patients (46%) were in the case group, and 21 female patients (42%) were in the healthy group, the ratio for which there is no statistically significant difference between the two groups (P> 0. 05). The average level of serum glucose, lipid profiles, as well as none of the hemodynamic factors had no statistically significant difference in the two groups.Only the mean systolic blood pressure was significantly lower in male patients than among men without the disease. Discussion: Despite the lack of difference in blood pressure between the case group and others, it seems that gender could plays a protective role against cardiovascular diseases in men with thalassemia major.
ITP, Early Presentation of Thymoma
Kamran Alimoghaddam,Forough Foroughi,Ali Shahriari Ahmadi,Vahid Farnia
International Journal of Hematology-Oncology and Stem Cell Research , 2005,
Abstract: Mediastinal neoplasms are uncommon tumors that can occur at any age but are most common through the fifth decades of life."nA wide variety of systemic disorders are associated with 71% of thymomas. The symptoms of these as sociated disorders often lead to the original discovery of the mediastinal tumor. A 35-year-old female with petechia and purpura was admitted to Sina hospital of the city of Hamadan in 5/6/2000. the serum platelet count was 4000/microliter. After the primary evaluations Idiopathic Thrombocytopenic Purpura (ITP) was diagnosed and after corticosteroid therapy serum platelet count increased. After 2 month she was admitted to the neurology ward of our hospital with diagnosis of cerebro vascular accident (CVA). In brain computed tomography (CT) scan a hyperdense lesion was reported that reveald hemorrhage in the temporoparietal region. The platelet count was 154000/microliter at this time which suggests the idea that some suppressive antibodies in the serum might lead to platelet disfunction. Two years later she was admitted to Shariati hospital with fatigue, left lid ptosis, speech disorder, bifacial weakness, diplopia and muscle force = 4/5. Myasthenia gravis was diagnosed and in the chest CT scan a density associated with thymus was reported. Thymectomy was performed for the patient and report of the pathologist was thymoma. After adjuvant radiotherapy serum platelet count increased and myasthenia gravis was improved and all of the patient's signs and symptoms resolved. ITP must be considered as one of the paraneoplastic symptoms of thymoma.
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