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Search Results: 1 - 10 of 72167 matches for " Alfredo José Lucendo "
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Importance of nutrition in inflammatory bowel disease
Alfredo José Lucendo, Livia Cristina De Rezende
World Journal of Gastroenterology , 2009,
Abstract: Inflammatory bowel disease (IBD) results from the interaction between an individual’s immune response and precipitant environmental factors, which generate an anomalous chronic inflammatory response in those who are genetically predisposed. Various feeding practices have been implicated in the origin of IBD based on epidemiological observations in developed countries, but we do not have solid evidence for the etiological role played by specific food types. IBD is associated with frequent nutritional deficiencies, the pattern and severity of which depends on the extent, duration and activity of the inflammation. Nutritional support allows these deficiencies in calories, macro- and micro-nutrients to be rectified. Enteral nutrition is also a primary therapy for IBD, especially for Crohn’s disease, as it allows the inflammatory activity to be controlled, kept in remission, and prevents or delays the need for surgery. Nutritional support is especially important in childhood IBD as an alternative to pharmacological treatment. This report discusses the complex relationship between diet and IBD.
Hepatic osteodystrophy: An important matter for consideration in chronic liver disease
Germán López-Larramona,Alfredo J Lucendo,Sonia González-Castillo,José M Tenias
World Journal of Hepatology , 2011, DOI: 10.4254/wjh.v3.i12.300
Abstract: Hepatic osteodystrophy (HO) is the generic term defining the group of alterations in bone mineral metabolism found in patients with chronic liver disease. This paper is a global review of HO and its main pathophysiological, epidemiological and therapeutic aspects. Studies examining the most relevant information concerning the prevalence, etiological factors, diagnostic and therapeutic aspects involved in HO were identified by a systematic literature search of the PubMed database. HO generically defines overall alterations in bone mineral density (BMD) (osteoporosis or osteopenia) which appear as a possible complication of chronic liver disease. The origin of HO is multifactorial and its etiology and severity vary in accordance with the underlying liver disease. Its exact prevalence is unknown, but different studies estimate that it could affect from 20% to 50% of patients. The reported mean prevalence of osteoporosis ranges from 13%-60% in chronic cholestasis to 20% in chronic viral hepatitis and 55% in viral cirrhosis. Alcoholic liver disease is not always related to osteopenia. HO has been commonly studied in chronic cholestatic disease (primary biliary cirrhosis and primary sclerosing cholangitis). Several risk factors and pathogenic mechanisms have been associated with the loss of BMD in patients with chronic liver disease. However, little information has been discovered in relationship to most of these mechanisms. Screening for osteopenia and osteoporosis is recommended in advanced chronic liver disease. There is a lack of randomized studies assessing specific management for HO.
Colorectal cancer surveillance in patients with inflammatory bowel disease: What s new?
Danila Guagnozzi,Alfredo J Lucendo
World Journal of Gastrointestinal Endoscopy , 2012, DOI: 10.4253/wjge.v4.i4.108
Abstract: Several studies assessing the incidence of colorectal cancer (CRC) in inflammatory bowel disease (IBD) patients have found an increased risk globally estimated to be 2 to 5 times higher than for the general population of the same age group. The real magnitude of this risk, however, is still open to debate. Research is currently being carried out on several risk and protective factors for CRC that have recently been identified in IBD patients. A deeper understanding of these factors could help stratify patient risk and aid specialists in choosing which surveillance program is most efficient. There are several guidelines for choosing the correct surveillance program for IBD patients; many present common characteristics with various distinctions. Current recommendations are far from perfect and have important limitations such as the fact that their efficiency has not been demonstrated through randomized controlled trials, the limited number of biopsies performed in daily endoscopic practice, and the difficulty in establishing the correct time to begin a given surveillance program and maintain a schedule of surveillance. That being said, new endoscopic technologies should help by replacing random biopsy protocols with targeted biopsies in IBD patients, thereby improving the efficiency of surveillance programs. However, further studies are needed to evaluate the cost-effectiveness of introducing these techniques into daily endoscopic practice.
Small bowel video capsule endoscopy in Crohn’s disease: What have we learned in the last ten years?
Alfredo J Lucendo,Danila Guagnozzi
World Journal of Gastrointestinal Endoscopy , 2011,
Abstract: Since its introduction in 2001, capsule endoscopy (CE) has become the most important advance in the study of small bowel disease, including Crohn’s disease (CD). This technique has been demonstrated to be superior to all other current forms of radiological investigation in detecting mucosal abnormalities of small bowel nonstricturing CD. CE has proven to be extremely useful in diagnosing CD in patients with inconclusive findings from ileocolonoscopy and x-ray-based studies. Almost half of all patients with CD involving the ileum also present lesions in proximal intestinal segments, with the small bowel being exclusively involved in up to 30% of all CD cases. Despite the widespread use of CE, several questions concerning the utility of this technique remain unanswered. The lack of commonly agreed diagnostic criteria for defining CD lesions with the aid of CE may have had an influence on the variation in diagnostic results for CE reported in the literature. The utility of CE in monitoring CD and in guiding therapy has also been proposed. Furthermore, CE could be a useful second-line technique for patients with an established diagnosis of CD and unexplained symptoms. Finally, as no threshold for CD diagnosis has been agreed upon, a severity scale of mucosal disease activity has not been universally followed. None of the available activity indexes based on CE findings has been independently validated. This article discusses several cutting-edge aspects of the usefulness of CE in CD 10 years after its introduction as a sensible method to study the small intestine.
Nutritional treatment in inflammatory bowel disease: An update Tratamiento nutricional de la enfermedad instestinal inflamatoria: Una actualización
Danila Guagnozzi,Sonia González-Castillo,Antonio Olveira,Alfredo J. Lucendo
Revista Espa?ola de Enfermedades Digestivas , 2012,
Abstract: Background and aims: enteral (EN) and parenteral (TPN) nutrition exert variable therapeutic effects on the induction and maintenance of remission in inflammatory bowel disease (IBD). This review aims to provide an updated discussion on the complex relationship between diet and IBD. Methods: medline, Cochrane and Scopus database searches were conducted. Sources cited in the articles obtained were also searched to identify other potential sources of information. Results: nutritional status is significantly compromised in IBD patients, especially those with Crohn's disease (CD). Apart from restoring malnourishment, dietary components contribute to modulate intestinal immune responses. Nutritional treatment is divided into support therapy and primary therapy to induce and maintain remission through TPN and EN. EN is considered a first-line therapy in children with active CD whereas it is usually used in adult CD patients when corticosteroid therapy is not possible. TPN has limited effects on IBD. En formula composition, in terms of carbohydrates, nitrogen source and bioactive molecules supplementation, differentially influence on IBD treatment outcomes. Other dietary components, such as poorly absorbed short-chain carbohydrate, polyols, and exogenous microparticles, also participate in the etiopathogenesis of IBD. Finally, new approaches to understanding the complex relationship between IBD and diet are provided by nutrigenenomic. Conclusion: further long-term, well-powered studies are required to accurately assess the usefulness of nutrition in treating IBD. In future research, the potential role of nutrient-gene interaction in drug trials and specific dietary formula compositions should be investigated in order to incorporate new knowledge about the etiopathology of IBD into nutritional intervention.
Resolution of metabolic syndrome after following a gluten free diet in an adult woman diagnosed with celiac disease
álvaro García-Manzanares,Alfredo J Lucendo,Sonia González-Castillo,Jesús Moreno-Fernández
World Journal of Gastrointestinal Pathophysiology , 2011, DOI: 10.4291/wjgp.v2.i3.49
Abstract: Adult celiac disease (CD) presents with very diverse symptoms that are clearly different from those typically seen in pediatric patients, including ferropenic anemia, dyspepsia, endocrine alterations and elevated transaminase concentration. We present the case of a 51-year-old overweight woman with altered basal blood glucose, hypercholesterolemia, hypertriglyceridemia and persisting elevated transaminase levels, who showed all the symptoms for a diagnosis of metabolic syndrome. Because she presented iron deficiency anemia, she was referred to the gastroenterology department and subsequently diagnosed with celiac disease after duodenal biopsies and detection of a compatible HLA haplotype. Gluten-free diet (GFD) was prescribed and after 6 mo the patient showed resolution of laboratory abnormalities (including recovering anemia and iron reserves, normalization of altered lipid and liver function parameters and decrease of glucose blood levels). No changes in weight or waist circumference were observed and no significant changes in diet were documented apart from the GFD. The present case study is the first reported description of an association between CD and metabolic syndrome, and invites investigation of the metabolic changes induced by gluten in celiac patients.
Germinación y sobrevivencia de esclerocios de (Phymatotrichopsis omnivora) en respuesta a NaOCl y suelo con glucosa
Samaniego Gaxiola, José Alfredo;
Agricultura técnica en México , 2008,
Abstract: sclerotia of phymatotrichopsis omnivora can survive for 20 years in the soil; however, if sclerotia are exposed to chemical agents or microbial competition in soil, survival is reduced to few weeks. the objective of this research was to study the germination and survival of p. omnivore sclerotia, treated first with a solution of naocl and then exposed to microbiota competition in soil supplemented with dextrose. the experiments were carried out at 'la laguna' research station of the national research institute for forestry, agriculture and livestock under a completely random factorial design. sclerotia were immersed in 200, 500 and 3 000 ppm naocl solutions during 0.3, 1, 8, and 72 h. at two temperatures, 15-20 and 28 °c, afterwards were placed in soil added with 0.0, 0.125, 0.25 and 0.5 mg g-1 of dextrose during 14 days under saturated conditions at 28 °c. sclerotia immersed into a 3 000 ppm solution of naocl during 20 min showed 90% germination in sterile sand and pda and only 15% in non-sterile sand and pda. when sclerotia were germinated before being immersed in naocl, viability was 100% in all substrates utilized. survival of sclerotia decreased with the increase in the time of immersion, concentration of naocl, and concentration of dextrose added to the soil. sclerotia immersed during one hour or more in 1 000 ppm or higher of naocl solution and placed in soil with 0.25 or 0.5 mg g-1 of added dextrose showed a maximum survival of 20%. sclerotia survival was high in some treatments at 15-20 °c than in similar treatments at 28 °c, possible due to a protective effect of naocl on sclerotia exposed to soil microbiota enhanced by added dextrose.
Acceso oportuno y permanencia escolar de alumnos de 6 a 14 a?os en Sonora, 2003-2005
Flores Valdez, José Alfredo;
Región y sociedad , 2009,
Abstract: the concept of quality in education is better interpreted by analyzing its different dimensions, in particular by making judgments about the efficiency, pertinence, and equity of the system as a whole. this approach has been used in various studies of the educational system based on the analysis of academic results, understood as synonymous of educational efficiency, ignoring the important and basic issue of access to education. there is much to be done; a detailed analysis of education coverage by age and grade not only shows meaningful progress in sonora between 2003 and 2005, but also highlights the main problems. in this sense, the biggest weaknesses are timely access and permanence, the key to academic success in children aged 10-12 and 14, who are in the final stages of elementary and middle school. the challenge is to avoid the repetition of school grades in elementary school as a preventive measure to avoid desertion, another big problem in middle school.
La vuelta de Jesús a los discípulos. Los rostros de la parusía en el Cuarto Evangelio
NORATTO G,JOSé ALFREDO;
Theologica Xaveriana , 2008,
Abstract: this paper explores the richness of the theological and eschatological conceptions subtending the language of the parousia in the texts of the literary and theological tradition of the fourth gospel. its originality and novelty are represented by the way in which the different traditions referring to the second advent of the lord are articulated, with the intention of expliciting the different eschatological horizons and of grasping the enormous hermeneutical potential of ?ρχομαι in its epiphanic dimension, and its extension in implicit language represented mainly by the verbs of vision, knowledge and revelation, and the paradigmatic figure of the paraclete.
La vuelta de Jesús a los discípulos. Los rostros de la parusía en el Cuarto Evangelio A volta de Jesus aos discípulos. Os rostos da Parusia no Quarto Evangelho The return of Jesus to the disciples. The faces of the Parousia in the Fourth Gospel
JOSé ALFREDO NORATTO G
Theologica Xaveriana , 2008,
Abstract: Explora la riqueza de concepciones cristológicas y escatológicas subyacentes al lenguaje de la Parusía, en los textos de la tradición literaria y teológica del Cuarto Evangelio. Su originalidad y novedad están representadas por la forma como se han articulado las distintas referencias a la segunda venida del Se or, con la intención de explicitar los distintos horizontes escatológicos y captar el enorme potencial hermenéutico de ρχομαι en su dimensión epifánica, y su extensión en el lenguaje implícito, representado especialmente por los verbos de visión, conocimiento y revelación, y la paradigmática figura del Paráclito. Neste artigo explora-se a variedade de concep es cristológicas e escatológicas, que saem ao linguagem da Parusia nos textos, da tradi o literária e teológica do quarto evangelho. Sua originalidade e novidade est o representadas pela maneira como se tem unido as diversas referências, á segunda volta do senhor com a inten o de expor os diferentes horizontes escatológicos e entender o grande potencial hermenêutico de ρχομαι na sua dimens o epifánica e sua inten o na linguagem explicita e representada especialmente pelos verbos de vis o, conhecimento e revela o, junto á paradigmática figura do Paráclito. This paper explores the richness of the theological and eschatological conceptions subtending the language of the Parousia in the texts of the literary and theological tradition of the Fourth Gospel. Its originality and novelty are represented by the way in which the different traditions referring to the second advent of the Lord are articulated, with the intention of expliciting the different eschatological horizons and of grasping the enormous hermeneutical potential of ρχομαι in its epiphanic dimension, and its extension in implicit language represented mainly by the verbs of vision, knowledge and revelation, and the paradigmatic figure of the Paraclete.
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