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Search Results: 1 - 10 of 2311 matches for " Alexis; Coronado "
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Eficacia de un ácido kaurénico extraído de la planta venezolana Wedelia trilobata (Asterácea) contra Leishmania (Viannia) braziliensis
Brito,Solanny; Crescente,Oscar; Fernández,Alexis; Coronado,Aura; Rodriguez,Noris;
Biomédica , 2006,
Abstract: introduction. leishmaniasis is a global public health problem without adequate treatment options, hence requiring research on new drug development. objective. our main objective was the evaluation of a kaurenic acid (ent-kaur-16-in-19-oico), isolated from the venezuelan plant wedelia trilobata (asteracea), on leishmania (v) braziliensis both in vivo and in vitro. materials and methods. the in vitro assay was performed using axenic amastigotes and promastigotes as well as infected and uninfected macrophages. parasites and macrophages were treated with concentrations of the compound varying between 10 and 250 μg/ml. the effect of the compound on cellular viability was evaluated by counting dead and living cells in a hemocytometer and by the colorimetric method using mtt (methylthiazoletetrazolium). for the in vivo assay, balb/c mice were infected subcutaneously with 1x106 promastigotes of l.(v.) braziliensis and afterwards treated with a daily dose of 30 mg/kg in 100 μl of kaurenic acid administered by intraperitoneal injection for one week. results. the compound had a lethal effect on axenic amastigotes and promastigotes with dl50 of 0.25 and 0.78 μg/ml, respectively, in 24 hours. low toxicity was observed for j774-g8 macrophages with a dl50 of 25 μg/ml and high viability (70-92%), while a moderate viability was observed for infected macrophages (37-81%), with concentrations of 25 μg/ml or less. additionally, a 70% reduction was observed in the size of the skin lesions in balb/c mice with no evident toxic effect. conclusion. the results indicate that this compound has a potent leishmanicidal effect on l.(v.) braziliensis.
Insurgencia y turismo: reflexiones sobre el impacto del turista politizado en Chiapas
Coronado, Gabriela
PASOS : Revista de Turismo y Patrimonio Cultural , 2008,
Abstract: The paper analyses the interrelations between politics and tourism considering the impact of political instability generated by the Zapatista indigenous rebellion on tourism in Chiapas, Mexico. By analysing tourist products and fieldwork observations the transformation of the tourist industry is explained as an effect of pressures from a new kind of visitor, “political tourists”. Attracted by the indigenous movement and its relevance as a global social movement, their political and ideological position created demands that affected interethnic organisational networks and the social value of tourism activity. As a response indigenous and non indigenous tourist agents generated new strategies for economic recovery, including changes in the organisational networks and marketing symbols and ideologies as “commodities”.
Among Absences
Gabriela Coronado
PORTAL : Journal of Multidisciplinary International Studies , 2011,
Abstract: Utilizando el género epistolar, una carta a mi madre, reflexiono sobre mi nueva vida e identidad como emigrante en Australia explorando mis percepciones sobre la diferencia cultural y lingüística. Lejos de mis hijas y nietos en México, en esta carta, tardíamente escrita, relato mis recuerdos, nostalgias y vivencias en el nuevo ambiente, y sobre todo, hablo de mis dificultades para manejar emocionalmente mi miedo a la ausencia en los momentos importantes del ciclo de vida, la enfermedad y la muerte. Using the epistolary genre, a letter to my mother, I reflect on my life and identity as an emigrant in Australia by exploring my perceptions of cultural and linguistic difference. Far from my children and grandchildren in Mexico, in this belatedly written letter I recall my memories, nostalgic feelings and expereinces in the new environment, and above all, I speak of my difficulties in mangaing emotionally my fears of being absent in the important moments of the cycle of life, sickness and death.
Discourses of Anti-corruption in Mexico. Culture of Corruption or Corruption of Culture?
Gabriela Coronado
PORTAL : Journal of Multidisciplinary International Studies , 2008,
Abstract: In the context of global capitalism the so-called developing countries are considered ‘commodities’ in offer in the global economy as emerging markets or for foreign investment. Countries need to show they are potentially highly competitive with low risk. The value of country characteristics is set by globalised managerial discourses, based on postcolonial ideologies that rate cultures and societies in terms of linear notions of progress and civilisation. Cultures and behaviours are judged positively or negatively according to the position countries supposedly have in the evolution of world society. In this framework one element that countries need to eradicate or reduce in order to be seen as ‘attractive’ is corruption. Towards this aim international and national government and non-government organisations have put in place anti-corruption campaigns. In communications with the general public, these schemes represent actors and acts of corruption through discursive strategies that characterize world cultures and their links with corruption in terms of postcolonial ideologies. In this paper I focus on the implications of the metaphor ‘culture of corruption’ for rating countries, questioning its effectiveness in anti-corruption campaigns. I argue that anti-corruption instruments based on postcolonial ideologies corrupt representations of national cultures and peoples behaviours, instead of targeting local and global sectors that gain from institutionalised corruption. Through the analysis of anti-corruption cultural texts publicly available in Mexico I illustrate how the ideological misrepresentation of corruption fails its stated aim, to transform a ‘culture of corruption’ into a ‘culture of legality’.
Entre ausencias
Gabriela Coronado
PORTAL : Journal of Multidisciplinary International Studies , 2009,
Abstract: Utilizando el género epistolar, una carta a mi madre, reflexiono sobre mi nueva vida e identidad como emigrante en Australia explorando mis percepciones sobre la diferencia cultural y lingüística. Lejos de mis hijas y nietos en México, en esta carta, tardíamente escrita, relato mis recuerdos, nostalgias y vivencias en el nuevo ambiente, y sobre todo, hablo de mis dificultades para manejar emocionalmente mi miedo a la ausencia en los momentos importantes del ciclo de vida, la enfermedad y la muerte.
The Smell of Memories. A Mexican Migrant’s Search for Emotional Sustainability through Mexican Films.
Gabriela Coronado
PORTAL : Journal of Multidisciplinary International Studies , 2011,
Abstract: For more than 10 years living as a Mexican migrant, between two countries (Mexico and Australia), two cities (Mexico City and Sydney), and two social worlds (Mexican and multicultural Australian ‘families-friends’), I have been immersed in a systematic process of self observation and self reflection on my life in my country of destination. During this time I have explored my memories of place and their relationship with my emotional experiences, looking for strategies to continue to be connected with my country of origin and my people. In this process I discovered films were especially significant in sustaining me emotionally. I benefited from the memory associations triggered by representations of Mexico in films produced by Mexicans or by filmmakers from other nationalities. By reflecting on my responses to those films, in this paper I explore how representations of their country of origin can impact on migrants’ emotional life. Using autoethnography, examining my own subjectivity as a way to arrive at a deeper grasp of these processes, I analyse the roles played by different senses in the process of recollection and in the emotional effects produced, which come to embody the experience. My particular focus in this article is the sense of smell triggered by complex interactions within the sensorium while watching films, producing associations and feelings through which I re-live my memories and maintain my emotional sustainability.
La violencia en la sociedad contemporánea
David Coronado
Espacio Abierto , 2007,
Abstract: Este artículo parte de que sociedad contemporánea se encuentra inmersa en una seria crisis institucional, en tanto que los espacios soporte están sujetos a las presiones de la globalización económica y las mutaciones sociales y culturales. Aquí aparecen las nuevas formas de socialización, los nuevos procesos de personalización, pero también algunas acciones ciudadanas que presentan comportamientos paralelos a las normas establecidas; estos procesos están en la base de la aparición de un nuevo tipo de violencia, la violencia destructiva, cuya única finalidad es servir de medio ad-hoc para manifestar la existencia de los sujetos.
Coordination Incentives in Cross-Border Macroprudential Regulation  [PDF]
Alexis Derviz, Jakub Seidler
Modern Economy (ME) , 2014, DOI: 10.4236/me.2014.511098

When national financial sector regulators need to mutually harmonize macroprudential policy decisions, imperfections of cross-border information exchange may undermine fair cooperation. Attempts to overcome the effects of informational distortions by delegating macroprudential policy to a supranational body are also likely to entail welfare losses. We study the tradeoff between macroprudential policy autonomy and centralization by means of a signaling game of imperfect information played by two national regulators. The model concentrates on informational frictions in an environment with otherwise fully aligned preferences. We show that even in the absence of evident conflicting goals, the non-transferable nature of some regulatory information creates misreporting incentives. Reporting accuracy is a part of a broader problem of strategic advantage-seeking by the national regulators. Therefore, cross-border coordination mechanisms, centralized or not, that limit strategic behavior are preferable to those allowing its full deployment. The results are applicable to systemic risk management by international organizations, including the relevant EU institutions.

The Impact of Residential and Non-Residential Demand on Location-Allocation Decision-Making: A Case Study of Modelling Suitable Locations for EMS in Leicester and Leicestershire, England UK  [PDF]
Emeka Chukwusa, Alexis Comber
Journal of Geographic Information System (JGIS) , 2018, DOI: 10.4236/jgis.2018.104020
Abstract: The research examines the impact of residential and non-residential demand on facility location planning by comparing results from two location models: travel-to-work (TTW) and Residential model. The TTW model considers short-term changes in the state of the population due to travel-to-work (non-residential demand). By contrast, the Residential model uses a static snap-shot of the population based on official census estimates (residential demand). Comparison of both models was based on a case study of Emergency Medical Services (EMS) location-allocation planning problem in Leicester and Leicestershire, England, UK. Results showed that the using a static residential demand surface to plan EMS locations overestimates actual demand coverage, compared to a non-residential demand surface. Differences in location-allocation results between the models underscore the importance of accounting for temporal changes in the state of the population when planning locations for health service facilities. The findings of the study have implications for siting of EMS, designing, and planning of EMS service catchments and allocation of prospective demand to EMS sites. The study concludes that consideration of temporal changes in the state of the population is important for reliable and efficient location-allocation planning.
“Sois vosotros valientes héroes. Somos nosotros simples humanos”.: La experiencia de la guerra del pacífico en los testimonios de los actores
Coronado Canales,David Angelo;
Diálogos Revista Electrónica de Historia , 2012,
Abstract: the chilean victory obtained at the war of the pacific is not only an object of study from a military point of view, with emphasis on the strategies and battles as meta stories worthy of belonging to the history of a nation; but it also is a discourse that allows the unification of a national community around it. in addition, however, it is important to listen to the participants’ testimonies and to recover their voices to know what they are telling us. the hypothesis in this article deals with how the official discourse about the chilean historiography and the memory of the same war have neglected fundamental historicity elements to understand the life experiences of these men, whose testimonies have remained so that we can decipher their subjectivities about their lives in campaign. the following article is a compilation of testimonies about the war of the pacific by chilean soldiers, who tell us their subjectivities and clarify what they felt, allowing us to separate the “man from the myth” and see them as the men they really were, historical subjects that for different reasons found themselves involved in a war in which they suffered, fought and which they memories survive to be studied.
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