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Search Results: 1 - 10 of 223616 matches for " Alexandra C. Cook "
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Who Voted for Trump in 2016?  [PDF]
Alexandra C. Cook, Nathan J. Hill, Mary I. Trichka, Grace J. Hwang, Paul M. Sommers
Open Journal of Social Sciences (JSS) , 2017, DOI: 10.4236/jss.2017.57013
Abstract: The authors use simple bilinear regression on statewide exit poll data to gauge the popularity of President Donald Trump in the 2016 election among voters in four levels of educational attainment (high school, some college, college, and postgraduate); three income groups (less than $50,000, $50,000 - $100,000, and more than $100,000); four age groups (18 - 29, 30 - 44, 45 - 64, and 65+); and two racial groups (white and non-white). Trump was found to be most popular among voters with a high school education, voters with annual incomes greater than $100,000, voters 65 years of age or older and white voters. Trump was found to be least popular among voters with a postgraduate degree, voters with annual incomes less than $50,000, voters under 30 years of age and non-white voters.
The Many Faces of Diversity: Overview and Summary
Cook, C
Online Journal of Issues in Nursing , 2003,
Abstract:
Initial and Continuing Competence in Education and Practice: Overview and Summary
Cook, C
Online Journal of Issues in Nursing , 1999,
Abstract:
Electronic Journals: Are They A Paradigm Shift?
Jones, S., Cook, C
Online Journal of Issues in Nursing , 2000,
Abstract: Ejournals are becoming an accepted and necessary means of meeting the demands for the dissemination of knowledge. This introductory article discusses the recent "explosion" of ejournals and provides an explanation of what is meant by an "ejournal." Ejournals are explored within the traditional context of scholarship and a discussion of the "serials crisis" that promoted the inception of ejournals is presented. After laying the groundwork for discussing scholarship in this new age of dissemination of scholarly information, the article discusses whether this digital form of publication can be called a "paradigm shift" in Kuhn's (1970) traditional sense of the word.
Review: Mao Zedong and China in the Twentieth- Century World, by Rebecca E. Karl,
Cook, Alexander C.
Journal of Historical Biography , 2011,
Abstract:
Nucleolar localization of an isoform of the IGF-I precursor
Daniel SW Tan, Alexandra Cook, Shern L Chew
BMC Cell Biology , 2002, DOI: 10.1186/1471-2121-3-17
Abstract: Chimeras containing exons 1 or 2 were located in the cytoplasm, consistent with a secretory pathway, and suggesting that both exons encoded functional signal peptides. Exon 5-containing chimeras localized to the nucleus and strongly to the nucleolus, while chimeras containing exon 6 or the upstream portion of exon 5 did not. Nuclear and nucleolar localization also occurred when the mature IGF-I domain was deleted from the chimeras, or when signal peptides were deleted.We have identified a nucleolar localization for an isoform of the human IGF-I precursor. The findings are consistent with the presence of a nuclear and nucleolar localization signal situated in the C-terminal part of the exon 5-encoded domain with similarities to signals in several other growth factors.Most human genes contain introns, which must be excised for correct gene expression. A substantial number of genes are alternatively spliced, generating a great number of protein isoforms [1]. In some cases, experimental evidence has been accrued for distinct function, but most variant isoforms have not been fully characterized. Human IGF-I is a 70 amino acid residue peptide with growth promoting and metabolic actions. Four of the six exons of the human IGF-I gene are alternatively spliced (Fig. 1A). The alternative splices encode different precursor peptides. Exons 1 and 2 are alternative leader exons derived from different transcription start sites, and encode part of the signal peptide [2,3]. The variant N-terminal domains encoded by IGF-I exons 1 or 2 are processed by canine microsomes, suggesting both are functional signal peptides [4]. Parts of exons 3 and 4 encode the mature IGF-I peptide and are constant. Alternative exons 5 and 6 encode different E domains. Part of the E domain encoded by exon 5 contains an amidated growth-promoting peptide [5], but there are little other functional data [6]. Despite the lack of experimental data on functional significance of the isoforms, there is conservation
Shoulda’ Put a Ring on It: Investigating Adult Attachment, Relationship Status, Anxiety, Mindfulness, and Resilience in Romantic Relationships  [PDF]
Aileen M. Pidgeon, Alexandra C. Giufre
Open Journal of Social Sciences (JSS) , 2014, DOI: 10.4236/jss.2014.211005
Abstract:

This study aimed to investigate the predictive ability of relationship status, anxiety, mindfulness, and resilience in relation to the two orthogonal dimensions of adult attachment: attachment anxiety and attachment avoidance. 156 participants completed measures assessing relationship status, adult attachment, anxiety, mindfulness and resilience. The results showed that resilience and the relationship status of single significantly predicted attachment anxiety, whereas anxiety and being either single or divorced significantly predicted attachment avoidance. A significant mediating role of resilience in the prediction of attachment anxiety from being single was also observed. The main implications of this study provided preliminary support for the significant predictive value of resilience in attachment anxiety.

Investor Na?veté and Asset Prices  [PDF]
Jonathan Cook
Journal of Mathematical Finance (JMF) , 2013, DOI: 10.4236/jmf.2013.34047
Abstract:

This paper describes strategic behavior in a nonequilibrium model of asset pricing with heterogeneous sophistication. Both risk and return are increasing in the na?veté of investors in the market. Optimal investment involves in considering the effect that na?e investors have on the market. Further, we derive a simple characterization of the asset price dynamics that results from an arbitrary combination of a countably infinite set of investor types.

A molecular, phylogenetic and functional study of the dADAR mRNA truncated isoform during Drosophila embryonic development reveals an editing-independent function  [PDF]
Sushmita Ghosh, Yaqi Wang, John A. Cook, Lea Chhiba, Jack C. Vaughn
Open Journal of Animal Sciences (OJAS) , 2013, DOI: 10.4236/ojas.2013.34A2003
Abstract: Adenosine Deaminases Acting on RNA (ADARs) have been studied in many animal phyla, where they have been shown to deaminate specific adenosines into inosines in duplex mRNA regions. In Drosophila, two isoform classes are encoded, designated full-length (contains the editase domain) and truncated (lacks this domain). Much is known about the full-length isoform, which plays a major role in regulating functions of voltage-gated ion channel proteins in the adult brain. In contrast, almost nothing is known about the functional significance of the truncated isoform. In situ hybridization shows that both isoform mRNA classes are maternally derived and transcripts for both localize primarily to the developing central nervous system. Quantitative RT-PCR shows that about 35% of all dADAR mRNA transcripts belong to the truncated class in embryos. 3’-RACE results show that abundance of the truncated isoform class is developmentally regulated, with a longer transcript appearing after the mid-blastula transition.3’-UTR sequences for the truncated isoform have been determined from diverse Drosophila species and important regulatory regions including stop codons have been mapped. Western analysis shows that both mRNA isoform classes are translated into protein during embryonic development, as full-length variant levels gradually diminish. The truncated protein isoform is present in every Drosophila species studied, extending over a period spanning about 40 x 106 years, implying a conserved function.
Parietal Cortex Signals Come Unstuck in Time
Erik P. Cook,Christopher C. Pack
PLOS Biology , 2012, DOI: 10.1371/journal.pbio.1001414
Abstract: Humans and other animals are surprisingly adept at estimating the duration of temporal intervals, even without the use of watches and clocks. This ability is typically studied in the lab by asking observers to indicate their estimate of the time between two external sensory events. The results of such studies confirm that humans can accurately estimate durations on a variety of time scales. Although many brain areas are thought to contribute to the representation of elapsed time, recent neurophysiological studies have linked the parietal cortex in particular to the perception of sub-second time intervals. In this Primer, we describe previous work on parietal cortex and time perception, and we highlight the findings of a study published in this issue of PLOS Biology, in which Schneider and Ghose [1] characterize single-neuron responses during performance of a novel “Temporal Production” task. During temporal production, the observer must track the passage of time without anticipating any external sensory event, and it appears that the parietal cortex may use a unique strategy to support this type of measurement.
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