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Search Results: 1 - 10 of 417919 matches for " Alexander M. Rubinov "
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G-coupling functions
Daniel Morales-Silva,Alexander M. Rubinov,Wilfredo Sosa
Mathematics , 2012, DOI: 10.1080/02331930701761557
Abstract: GAP functions are useful for solving optimization problems, but the literature contains a variety of different concepts of GAP functions. It is interesting to point out that these concepts have many similarities. Here we introduce G-coupling functions, thus presenting a way to take advantage of these common properties.
On Convex Polytopes in the d-dimensional Space Containing and Avoiding Zero
Alexander Kelmans,Anatoliy Rubinov
Computer Science , 2012,
Abstract: The goal of this paper is to establish certain inequalities between the numbers of convex polytopes in the d-dimensional space "containing" and "avoiding" zero provided that their vertex sets are subsets of a given finite set of points in the space.
-porosity in monotonic analysis with applications to optimization
A. M. Rubinov
Abstract and Applied Analysis , 2005, DOI: 10.1155/aaa.2005.287
Abstract: We introduce and study some metric spaces of increasing positivelyhomogeneous (IPH) functions, decreasing functions, and conormal(upward) sets. We prove that the complements of the subset ofstrictly increasing IPH functions, of the subset of strictlydecreasing functions, and of the subset of strictly conormal setsare σ-porous in corresponding spaces. Some applications tooptimization are given.
Weight-conserving characterization of complex functional brain networks
Mikail Rubinov,Olaf Sporns
Quantitative Biology , 2011, DOI: 10.1016/j.neuroimage.2011.03.069
Abstract: Complex functional brain networks are large networks of brain regions and functional brain connections. Statistical characterizations of these networks aim to quantify global and local properties of brain activity with a small number of network measures. Important functional network measures include measures of modularity (measures of the goodness with which a network is optimally partitioned into functional subgroups) and measures of centrality (measures of the functional influence of individual brain regions). Characterizations of functional networks are increasing in popularity, but are associated with several important methodological problems. These problems include the inability to characterize densely connected and weighted functional networks, the neglect of degenerate topologically distinct high-modularity partitions of these networks, and the absence of a network null model for testing hypotheses of association between observed nontrivial network properties and simple weighted connectivity properties. In this study we describe a set of methods to overcome these problems. Specifically, we generalize measures of modularity and centrality to fully connected and weighted complex networks, describe the detection of degenerate high-modularity partitions of these networks, and introduce a weighted-connectivity null model of these networks. We illustrate our methods by demonstrating degenerate high-modularity partitions and strong correlations between two complementary measures of centrality in resting-state functional magnetic resonance imaging (MRI) networks from the 1000 Functional Connectomes Project, an open-access repository of resting-state functional MRI datasets. Our methods may allow more sound and reliable characterizations and comparisons of functional brain networks across conditions and subjects.
The Infection Hypothesis of Schizophrenia: A Systematic Review  [PDF]
Alexander M. Scharko
Journal of Behavioral and Brain Science (JBBS) , 2011, DOI: 10.4236/jbbs.2011.12007
Abstract: Objectives: The objective of this paper is to accomplish a systematic review of the infection hypothesis of schizophrenia. Methods: All English language publications from January 1989 to March 2010 as related to infection and schizophrenia were obtained. Each study selected for analysis must either deal with the direct infection of an individual and schizophrenia or maternal infection during pregnancy and the subsequent development of schizophrenia in the offspring. The primary outcome measure was the calculated odds ratio and 95% confidence interval (CI). Results: Over 300 titles and abstracts were reviewed. Eight retrospective studies regarding in utero exposure were analyzed. Five nested case-controlled studies yielded an overall odds ratio of 3.58 (95% CI: 2.71 - 4.71) with a percent attributable risk of 6.3%. Three Scandinavian populational studies yielded an overall odds ratio of 0.62 (95% CI: 0.49 - 0.79). Twenty-six papers were identified as retrospective studies focused on linking evidence of past infection in individuals with history of schizophrenia. A total of 77 microorganisms were assessed with 18 (23.4%) showing a positive association with schizophrenia. But positive associations in a given trial were negative in other trials. Conclusions: Direct infection of an individual as a cause of schizophrenia is unlikely. Results were mixed regarding maternal infection, in utero exposure, and the later development of schizophrenia in the offspring and likely accounts for a modest proportion of those with schizophrenia, possibly 6%.
Functionalization of Silica Surface with UV-Active Molecules by Multivalent Organosilicon Spacer  [PDF]
Olga Iliashevsky, Elina Rubinov, Yafa Yagen, Moshe Gottlieb
Open Journal of Inorganic Chemistry (OJIC) , 2016, DOI: 10.4236/ojic.2016.63012
Abstract: Immobilization of active molecules by attachment onto solid surfaces is a well-established practice in many processes and applications. Silica micro- and nano-particles are attractive candidates as support for active molecules as a result of a combination of desirable properties. The present study deals with grafting of a functional UV active molecule onto silica surfaces via hydrosilylation reactions using multivalent organosilicon spacers. Different types of organosilicon precursors based on dimethylsiloxysilanes containing multiple SiH groups were used as spacers between vinyl-modified silica surface and the benzotriazole UV-absorber (UVA). Firstly, the surface of silica was modified with vinyltrimetoxsisilane coupling agent. The UVA molecules were attached to the silica-vinyl by a two-step procedure involving hydrosilylation reaction. The successful grafting was confirmed by FTIR, TGA and UV-Vis characterization. More than fivefold increase in UVA loading was found for the MH30 multifunctional spacer, which contains approximately 75 SiH groups per molecule, when compared to a four-functional spacer. Furthermore a branched, bulky six-functional spacer is preferred over a linear spacer of the same functionality. UV activity of functionalized silica was studied by UV-Vis spectroscopy, indicating that the immobilization of UVA onto silica surface has not altered its UV absorbance properties.
Impacts of Modern Glacier Changes on Surface Water Resources in Western and Northern Mongolia  [PDF]
Alexander Orkhonselenge, Jonathan M. Harbor
Journal of Water Resource and Protection (JWARP) , 2018, DOI: 10.4236/jwarp.2018.106031
Abstract: Water trapped in glaciers and in lakes impounded by landforms created by glaciers (glacial lakes) are an important component of the hydrology and water resources in high mountain areas of Central Asia. Changes in modern glaciers and glacial lakes are an important component of the hydrology of watersheds in the Mongolian Altai and Khuvsgul Mountain Ranges, western and northern Mongolia, respectively. Here we focus on Mt. Ikh Turgen and Mt. Munkh Saridag, isolated mountains of the Mongolian Altai and Khuvsgul Mountain Ranges, respectively. We use remote sensing to track changes in modern glaciers over time with mapping at scales of 1:200,000 for Mt. Ikh Turgen and 1:90,000 for Mt. Munkh Saridag based on imagery from Google Earth, 30 m resolution Aster Digital Elevation Model (DEM) and 30 m resolution Landsat 5 TM. Mt. Ikh Turgen lost 45.6% of its total glacier area between 1970 (41.4 km2) and 2011 (18.9 km2) and the Equilibrium Line Altitude (ELA) of the glaciers increased in elevation by 98 m and 144 m on north and south aspects, respectively. Mt. Munkh Saridag lost 57.3% of its total glacier area between 1970 (901 m2) and 2007 (381 m2) and the local ELA rose by 47 m and 80 m on north and south aspects, respectively. These mountains are located at similar latitudes, and so the greater percentage loss of glacier area in Mt. Munkh Saridag and faster changes in ELAs in Mt. Ikh Turgen may reflect variations in elevation and aspect, duration of solar radiation, and vulnerability to solar radiation, as well as variations in glacier scale. This study demonstrates the importance of spatial analyses of modern glaciers in understanding the context of hydrological changes within which any sustainable water resource management plan must be situated.
Dynamic Change of Global and Local Information Processing in Propofol-Induced Loss and Recovery of Consciousness
Martin M. Monti ,Evan S. Lutkenhoff,Mikail Rubinov,Pierre Boveroux,Audrey Vanhaudenhuyse,Olivia Gosseries,Marie-Aurélie Bruno,Quentin Noirhomme,Mélanie Boly,Steven Laureys
PLOS Computational Biology , 2013, DOI: 10.1371/journal.pcbi.1003271
Abstract: Whether unique to humans or not, consciousness is a central aspect of our experience of the world. The neural fingerprint of this experience, however, remains one of the least understood aspects of the human brain. In this paper we employ graph-theoretic measures and support vector machine classification to assess, in 12 healthy volunteers, the dynamic reconfiguration of functional connectivity during wakefulness, propofol-induced sedation and loss of consciousness, and the recovery of wakefulness. Our main findings, based on resting-state fMRI, are three-fold. First, we find that propofol-induced anesthesia does not bear differently on long-range versus short-range connections. Second, our multi-stage design dissociated an initial phase of thalamo-cortical and cortico-cortical hyperconnectivity, present during sedation, from a phase of cortico-cortical hypoconnectivity, apparent during loss of consciousness. Finally, we show that while clustering is increased during loss of consciousness, as recently suggested, it also remains significantly elevated during wakefulness recovery. Conversely, the characteristic path length of brain networks (i.e., the average functional distance between any two regions of the brain) appears significantly increased only during loss of consciousness, marking a decrease of global information-processing efficiency uniquely associated with unconsciousness. These findings suggest that propofol-induced loss of consciousness is mainly tied to cortico-cortical and not thalamo-cortical mechanisms, and that decreased efficiency of information flow is the main feature differentiating the conscious from the unconscious brain.
South African Airborne Operations
M Alexander
Scientia Militaria: South African Journal of Military Studies , 2003,
Abstract:
The Militarisation of South African White Society, 1948-1990
M Alexander
Scientia Militaria: South African Journal of Military Studies , 2000,
Abstract:
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