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Search Results: 1 - 10 of 5534 matches for " Albert RK "
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Mannose-binding lectin deficiency and acute exacerbations of chronic obstructive pulmonary disease
Albert RK,Connett J,Curtis JL,Martinez FJ
International Journal of COPD , 2012,
Abstract: Richard K Albert,1 John Connett,2 Jeffrey L Curtis,3,4 Fernando J Martinez,3 MeiLan K Han,3 Stephen C Lazarus,5 Prescott G Woodruff51Medicine Service, Denver Health and Department of Medicine, University of Colorado Denver, Denver, CO, 2Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, 3Pulmonary and Critical Care Medicine, Department of Medicine, University of Michigan, Ann Arbor, MI, 4Pulmonary and Critical Care Medicine, VA Medical Center, Ann Arbor, MI, 5Pulmonary and Critical Care Medicine, Department of Medicine, and Cardiovascular Research Institute, University of California, San Francisco, CA, USABackground: Mannose-binding lectin is a collectin involved in host defense against infection. Whether mannose-binding lectin deficiency is associated with acute exacerbations of chronic obstructive pulmonary disease is debated.Methods: Participants in a study designed to determine if azithromycin taken daily for one year decreased acute exacerbations had serum mannose-binding lectin concentrations measured at the time of enrollment.Results: Samples were obtained from 1037 subjects (91%) in the trial. The prevalence of mannose-binding lectin deficiency ranged from 0.5% to 52.2%, depending on how deficiency was defined. No differences in the prevalence of deficiency were observed with respect to any demographic variable assessed, and no differences were observed in time to first exacerbation, rate of exacerbations, or percentage of subjects requiring hospitalization for exacerbations in those with deficiency versus those without, regardless of how deficiency was defined.Conclusion: In a large sample of subjects with chronic obstructive pulmonary disease selected for having an increased risk of experiencing an acute exacerbation of chronic obstructive pulmonary disease, only 1.9% had mannose-binding lectin concentrations below the normal range and we found no association between mannose-binding lectin concentrations and time to first acute exacerbation or frequency of acute exacerbations during one year of prospective follow-up.Keywords: COPD, acute exacerbations, mannose-binding lectin
Mannose-binding lectin deficiency and acute exacerbations of chronic obstructive pulmonary disease
Albert RK, Connett J, Curtis JL, Martinez FJ, Han MK, Lazarus SC, Woodruff PG
International Journal of Chronic Obstructive Pulmonary Disease , 2012, DOI: http://dx.doi.org/10.2147/COPD.S33714
Abstract: nnose-binding lectin deficiency and acute exacerbations of chronic obstructive pulmonary disease Original Research (852) Total Article Views Authors: Albert RK, Connett J, Curtis JL, Martinez FJ, Han MK, Lazarus SC, Woodruff PG Published Date November 2012 Volume 2012:7 Pages 767 - 777 DOI: http://dx.doi.org/10.2147/COPD.S33714 Received: 09 May 2012 Accepted: 09 July 2012 Published: 23 November 2012 Richard K Albert,1 John Connett,2 Jeffrey L Curtis,3,4 Fernando J Martinez,3 MeiLan K Han,3 Stephen C Lazarus,5 Prescott G Woodruff5 1Medicine Service, Denver Health and Department of Medicine, University of Colorado Denver, Denver, CO, 2Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, 3Pulmonary and Critical Care Medicine, Department of Medicine, University of Michigan, Ann Arbor, MI, 4Pulmonary and Critical Care Medicine, VA Medical Center, Ann Arbor, MI, 5Pulmonary and Critical Care Medicine, Department of Medicine, and Cardiovascular Research Institute, University of California, San Francisco, CA, USA Background: Mannose-binding lectin is a collectin involved in host defense against infection. Whether mannose-binding lectin deficiency is associated with acute exacerbations of chronic obstructive pulmonary disease is debated. Methods: Participants in a study designed to determine if azithromycin taken daily for one year decreased acute exacerbations had serum mannose-binding lectin concentrations measured at the time of enrollment. Results: Samples were obtained from 1037 subjects (91%) in the trial. The prevalence of mannose-binding lectin deficiency ranged from 0.5% to 52.2%, depending on how deficiency was defined. No differences in the prevalence of deficiency were observed with respect to any demographic variable assessed, and no differences were observed in time to first exacerbation, rate of exacerbations, or percentage of subjects requiring hospitalization for exacerbations in those with deficiency versus those without, regardless of how deficiency was defined. Conclusion: In a large sample of subjects with chronic obstructive pulmonary disease selected for having an increased risk of experiencing an acute exacerbation of chronic obstructive pulmonary disease, only 1.9% had mannose-binding lectin concentrations below the normal range and we found no association between mannose-binding lectin concentrations and time to first acute exacerbation or frequency of acute exacerbations during one year of prospective follow-up.
Wireless Capsule Cystoscopy: How Near? How Far?  [PDF]
Hakan ?ztürk
Open Journal of Urology (OJU) , 2014, DOI: 10.4236/oju.2014.44007
Abstract:

It is a fact that performing endoscopy using conventional methods requires substantial time and development of alternative diagnostic modalities. Replacement of rigid endoscopes with flexible and digital devices in time, faster performance of the procedures and reduced time for them to turn back to work brought about the expectancy. It was possible that easier and more reliable methods could exist. Idea of capsule endoscopy was born following examination of the gastrointestinal tract with an endoscope with shape of a capsule. Although idea of capsule endoscopy was suggested long years ago, it fell behind the advances in conventional step of the endoscopy, especially developmental speed of the flexible devices. Furthermore, three-dimensional (3D) organ views can be processed digitally by means of sophisticated software in the fields of computerized tomography and magnetic resonance imaging. Thus, virtual cystoscopy of high resolution and specificity is possible by means of both methods. Wireless capsule endoscopy is still in the experimental stage. “Steerable independent intracorporeal endoscope” with feature of consecutive instillation in addition to its diagnostic utility is not a dream.

Determinants of Expected Wages of Unemployed Workers in Turkey  [PDF]
?smail ?entürk
Modern Economy (ME) , 2015, DOI: 10.4236/me.2015.67076
Abstract: In this study, determinants of expected wages of unemployed individuals in Turkey have been analyzed. In addition to duration of unemployment, reservation wage, and previous wage, the effect of demographic and economic factors has also been studied. The data which were obtained from 1607 individuals who were included in a nationwide survey has been analyzed by the two stage least squares method. Our findings show that previous wage, age, the level of education, the number of foreign languages spoken, the number of job offers the individual receives, and whether the individual receives state assistance determine the expected wage. Obtained results are important because they show how individuals price the variables that determine their own productivities. In addition, our study sheds light on relationships between reservation wage, duration of unemployment, previous wage, and expected wage within the context of Turkey.
Inverse Problem on Heat Conduction in Heterogeneous Medium  [PDF]
Albert Schwab
American Journal of Computational Mathematics (AJCM) , 2014, DOI: 10.4236/ajcm.2014.41003
Abstract:

Under consideration is a nonclassical stationary problem on heat conduction in a body with the pre-set surface temperature and heat flow. The body contains inclusions at unknown locations and with unknown boundaries. The body and inclusions have different constant thermal conductivities. The author explores the possibility of locating inclusions. The article presents an integral criterion based on which a few statements on identification of inclusions in a body are proved.

Post Mid-Staffordshire Inquiries Reaction, in and about the National Health Service (NHS), England. The Missing Pieces: Organizational, Care and Virtue Ethics Perspectives  [PDF]
Albert Coleman
International Journal of Clinical Medicine (IJCM) , 2014, DOI: 10.4236/ijcm.2014.516131
Abstract:

The release of the Mid Staffordshire hospital report otherwise called the Francis report once again ignited the debate about the issue of abuse of especially vulnerable patients, while navigating the care pathway as inpatients in hospitals; within the National health service (NHS), England. Once more the official reaction from the NHS directorate is more “standards” to monitor failed standards in patient care. Of interest in the official responses so far, are the unheard voices addressing the issue of healthcare and organizational ethics concerns that need revisiting. This article seeks to revisit practice, systems and care issues leading to incidents of the type of the Staffordshire abuses, and the important but yet unheralded place of organizational and care ethics in helping to curb such abuses from re-occurring.

Road Traffic Accidents in Ghana: A Public Health Concern, and a Call for Action in Ghana, (and the Sub-Region)  [PDF]
Albert Coleman
Open Journal of Preventive Medicine (OJPM) , 2014, DOI: 10.4236/ojpm.2014.411092
Abstract: This paper highlights the increasing problem of road traffic accident (RTA) related morbidity and mortality in Ghana, and the public health measures needed to control the problem. Descriptive data in the public domain from statutory bodies and media houses reports on country RTA information, as well as academic papers on the problem, were used as source of information about the problem. The observed trend in Ghana indicates that RTA related fatalities and injuries continue to be increasing, as morbidity and mortality factors since the year 2000. Most of the remedial measures suggested in academic papers, and state agencies measures to curb the RTA trend in Ghana to date, have discussed the problem in terms of injury and safety issues/measures. This paper suggests that the increasing RTAs with associated morbidity and mortality in Ghana need to be looked at more as a public health problem and priority that requires prompt tackling using a public health problem orientated approach and measures, than just as a safety problem due to RTAs’, as is currently done.
New Wideband Notch Antennas for Communication Systems  [PDF]
Albert Sabban
Wireless Engineering and Technology (WET) , 2016, DOI: 10.4236/wet.2016.72008
Abstract: Wireless communication industry is in rapid growth in the last years. Due to the huge progress in development of communication systems in the last decade development of wideband communication systems is continuous growth. However, development of wideband efficient antennas is one of the major challenges in development of wideband wireless communication systems. Low cost compact antennas are crucial in the development of communication systems. Printed notch antennas and miniaturization techniques are employed to develop efficient compact notch antennas. Fractal technology is used to improve the electrical performance and efficiency of notch antennas. Design tradeoffs, computed and measured results of wideband notch antennas with high efficiency are presented in this paper. All antennas are analyzed by using 3D full-wave software. The paper presents new compact Ultra-Wideband notch antenna 1 GHz to 6 GHz, a wideband notch antenna 2.1 GHz to 7.8 GHz and a 5.8 GHz to 18 GHz fractal notch antenna.
Wearable Antenna Measurements in Vicinity of Human Body  [PDF]
Albert Sabban
Wireless Engineering and Technology (WET) , 2016, DOI: 10.4236/wet.2016.73010
Abstract: This paper presents measurements techniques of wearable antennas and RF medical systems in vicinity of human body. The antennas radiation characteristics on human body have been measured by using a phantom. The phantom electrical characteristics represent the human body electrical characteristics. The phantom has a cylindrical shape with a 40 cm diameter and a length of 1.5 m. The phantom electrical characteristics are similar to the human body electrical characteristics. The antenna under test was placed on the phantom during the measurements of the antennas radiation characteristics. The phantom was employed to compare the electrical performance of several new wearable antennas. The phantom was also employed to measure the electrical performance of several antenna belts in vicinity of human body. The results of antenna with thinner belt are better than the results of the same antenna array with thicker belt.
New Wideband Passive and Active Wearable Energy Harvesting Systems for Wearable Sensors  [PDF]
Albert Sabban
Journal of Sensor Technology (JST) , 2017, DOI: 10.4236/jst.2017.74004
Abstract: Abstract: Demand for green energy is in continuous growth. Wide band efficient wearable systems and antennas are crucial for energy harvesting wearable systems for medical and sport wearable sensors. Small harvesting antennas suffer from low efficiency. The efficiency of energy harvesting wearable systems may be improved by using active wearable harvesting systems with low power consumption. Amplifiers may be connected to the wearable antenna feed line to increase the system dynamic range. Novel active wearable harvesting systems are presented in this paper. Notch and Slot antennas are low profile and low cost and may be employed in energy harvesting wearable systems. The wearable harvesting system components are assembled on the same PCB. The notch and slot antennas bandwidth is up to 100% for VSWR better than 3:1. The slot antenna gain is around 3 dBi with efficiency higher than 90%. The antennas electrical parameters were computed in vicinity of the human body. The active antenna gain is 24 ± 2.5 dB for frequencies from 200 MHz to 900 MHz. The active antenna gain is 12.5 ± 2.5 dB for frequencies from 1 GHz to 3 GHz. The active slot antenna Noise Figure is 0.5 ± 0.3 dB for frequencies from 200 MHz to 3.3 GHz.
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