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Search Results: 1 - 10 of 402916 matches for " Alban Silvana M "
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Identification of mimotopes of Mycobacterium leprae as potential diagnostic reagents
Alban Silvana M,de Moura Juliana Ferreira,Minozzo Jo?o Carlos,Mira Marcelo Távora
BMC Infectious Diseases , 2013, DOI: 10.1186/1471-2334-13-42
Abstract: Background An early diagnostic test for detecting infection in leprosy is fundamental for reducing patients’ sequelae. The currently used lepromin is not adequate for disease diagnosis and, so far, no antigen to be used in intradermoreaction has proved to be sensitive and specific for that purpose. Aiming at identifying new reagents to be used in skin tests, candidate antigens were investigated. Methods Random peptide phage display libraries were screened by using antibodies from leprosy patients in order to identify peptides as diagnostic reagents. Results Seven different phage clones were identified using purified antibodies pooled from sera of leprosy patients. When the clones were tested with serum samples by ELISA, three of them, 5A, 6A and 1B, allowed detecting a larger number of leprosy patients when compared to controls. The corresponding peptides expressed by selected phage clones were chemically synthesized. A pilot study was undertaken to assess the use of peptides in skin tests. The intradermal challenge with peptides in animals previously sensitized with Mycobacterium leprae induced a delayed-type hypersensitivity with peptide 5A (2/5) and peptide 1B (1/5). In positive controls, there was a 3/5 reactivity for lepromin and a 4/5 reactivity of the sensitized animals with soluble extract of M. leprae. Conclusions The preliminary data suggest that may be possible to develop reagents with diagnostic potential based on peptide mimotopes selected by phage display using polyclonal human antibodies.
Factors Influencing the Weight Gain of Piglets During the Nursing Period: Preliminary Results
Johansen M,Alban L,Kj?rsgaard HD,B?kbo P
Acta Veterinaria Scandinavica , 2003, DOI: 10.1186/1751-0147-44-s1-p72
Surgical Clipping of a Basilar Tip Aneurysm: Case Report and Literature Review  [PDF]
Médard Kakou, Alban Slim Mbende, Fulbert Kouakou, Phanré Doua
Open Journal of Modern Neurosurgery (OJMN) , 2017, DOI: 10.4236/ojmn.2017.73007
Abstract: Basilar tip aneurysms account for 5% - 8% of all intracranial aneurysms. They are known to rupture more frequently than aneurysms in other locations. Surgical clipping of basilar apex aneurysms however challenging; remains the treatment of choice in Ivory Coast due in part, to multiple technical barriers. A 60-year-old right-handed patient presented to our Neurosurgical Unit in February 2nd 2013 after a sudden onset of altered consciousness. Neurological examination revealed both an upper motor neuron and meningeal syndromes with a Glasgow Coma Scale of 12. Brain NECT scan and a subsequent brain CT angiography showed a subarachnoid haemorrhage and a 3.8 mm (height) × 5.2 mm (width) basilar tip aneurysm respectively. Surgical clipping of the aneurysm was indicated but due to multiple technical barriers, surgery was delayed and the patient underwent surgery after the critical vasospasm period. The patient developed a hospital acquired pneumonia after surgery and was successfully treated with antibiotics. Since her discharge, she has been asymptomatic. We sought to report this case of a basilar apex aneurysm successfully occluded with non-ferromagnetic SUGITA clips and to share our experience of clipping these lesions through the frontotemporal approach. The patient was informed that non identifying information from the case would be submitted for publication, and she provided consent.
Pericallosal Artery Aneurysms: Twenty-Six Years of Microneurosurgical Endeavor in Three Major Neurosurgical Centers in Abidjan  [PDF]
Médard Kakou, Alban Slim Mbende, Daouda Sissoko, Fulbert Kouakou
Open Journal of Modern Neurosurgery (OJMN) , 2017, DOI: 10.4236/ojmn.2017.74014
Abstract: We present our experience of microsurgical treatment of pericallosal artery aneurysms (PCAA) in three neurosurgical centers in Abidjan (Ivory Coast) from 1990 to 2016. This present study aimed to evaluate characteristics of 6 patients with PCAA treated during a 26-year period and to establish the rate, clinical nuances, anatomical variations and respective microsurgical approaches of PCAA in Abidjan. We analyzed medical files of all 93 patients admitted for an intracranial aneurysm between 1990 and 2016 and focused on the 6 patients who were treated for a PCCA. The mean age of patients was 37 years, half of whom were less than 30 years old. They were 3 men and 3 women. The time from first symptom to admission was more than 3 days, but less than 16 days. Five out of six patients had ruptured aneurysms and the clinical condition on admission was WFNS grade 0 one patient (16.67%) and WFNS I-III five patients (83.33%). Analysis of radiological data revealed Fischer grade IV three patients and Fischer grade I-II three patients. A total of 7 PCCA were recorded and they accounted for 6.19% of all intracranial aneurysms and 9.72% of all anterior circulation aneurysms. Six out of seven aneurysms (85.71%) were either smaller (2 - 6 mm) or middle sized (6 - 15 mm). There was only one (14.29%) giant PCA aneurysm (>25 mm). According to the location, two aneurysms (28.57%) were located on the A2 segment of the pericallosal artery (PCA) and five (71.43%) on the A3 segment of the artery. We found 4 cases of saccular aneurysms (57.14%) and 3 cases of fusiform aneurysms (42.86%), two of which were located on A2 segments of the 2 PCA on the same patient (16.67%). We didn’t find any PCA anatomical variation associated with any of the 7 aneurysms. Two patients developed perioperative rebleeding and in 1 case a severe preoperative hydrocephalus was diagnosed. The median time from rupture to surgery was 59.5 days with a range of 14 to 180 days. Treatment techniques included 4 clipping (57.14%) and 3 wrapping (42.86%). In 2 cases there was premature perioperative rupture of the aneurysm (33.33%). One patient (16.67%) had postoperative persistent anosmia and, we didn’t record any fatal outcome in our series. PCAA remain rare anterior circulation aneurysms, located in the vast majority of cases, on the A3 segment of the PCA and, are mostly smaller in size even when ruptured. Microsurgical clipping remains a safe and effective treatment option despite their complex surgical approaches and the risk of premature rupture.
Combinaison d'informations géographiques en mode image: application à l'estuaire de la Seine
Mappemonde , 1993,
Abstract: En présentant une série de traitements visant la combinaison et la représentation cartographique d’informations géographiques, l’objectif est de promouvoir la gestion d’informations à caractère spatial en mode image.
La lutte internationale contre la piraterie au large de la Somalie depuis 2008
Alban Sciascia
EchoGéo , 2009,
Abstract: La piraterie maritime est devenue en quelques mois un phénomène hautement médiatisé. Face à cet intérêt croissant, il convient de se questionner sur les intérêts profonds qui semblent à l’origine de cette lutte globale contre la piraterie. En se fondant sur un corpus varié et sur une analyse des forces en présence, nous essayerons de nous interroger sur les motivations profondes qui aujourd’hui permettent la mise en uvre d’une coopération internationale au large des c tes somaliennes. Suite à cette démonstration, étayée d’exemples précis, nous nous intéresserons à la mise en uvre de cette coopération, à ses limites ainsi qu’à ses conséquences. In few months, Medias has firmly focused on the maritime piracy. At the hands of this increasing interest about this phenomenon, it is advisable to question ourselves on the deep interest which could be the sources of this global struggle against piracy. Basing on a diversified body of knowledge and on an analysis of the powers at play, we will questioning about the deeper motives of the States attendees that allow the deployment of an international coalition of the Somali coast. After having summed up this point, we will take an interest on the implementation, limits and consequences of this cooperation.
Health and Social Conditions of Older People in Albania: Baseline Data from a National Survey
Alban Ylli
Public Health Reviews , 2010,
Abstract: The paper presents the data from a household survey in a representative sample of the population of individuals over 65 years old in three regions of Albania. The survey included a quantitative assessment of socioeconomic situation including poverty, social participation and social exclusion, as well as assessment of ill-health including limitations of daily living activities and chronic conditions. It was found that older people in urban areas are better covered with social security as compared to older residents in rural and informal areas. One third (32%) of participants reported not good or bad health and the majority (57%) of them were poor or very poor. Significant differences were found with individuals residing in informal areas around Tirana, reporting worse health conditions than elderly people living in urban areas. Approximately one fifth (18%) were totally or partially isolated from social networks. Prevalence of selected chronic conditions ranged from 9 percent to 58 percent. Almost the totality (93%) of the sample experienced some pain and 9 percent were bed-bound. More than one in four (27%) reported not receiving medical care when they needed it. Demographic trends mixed with a society in economic and political transition raise concerns about increasing needs for care and social inclusion of older people. Moreover, there is a low level of preparation of this society to cope with chronic diseases and long-term care. The findings suggest specific policies and actions to be considered by a number of stakeholders, including government and civic society.
A Insustentabilidade do Turismo no Brasil e o Sucesso de Praia do Forte: uma análise exploratória com base na nova economia institucional
Marcus Alban
Revista Turismo em Análise , 2010,
Comment devient-on fran ais quand on est juif et polonais ? How becoming French when you are a Polish Jew ? Compared itineraries from Holocaust survivors
Alban Perrin
Bulletin du Centre de Recherche Fran?ais de Jérusalem , 2012,
Abstract: De nombreux Juifs polonais, fuyant la misère et l’antisémitisme, vinrent s’installer en France avant la Seconde Guerre mondiale. En 1940, l’occupation allemande et l’avènement du régime de Vichy mirent fin brutalement à leurs espoirs d’intégration. Fichés, spoliés, raflés, déportés, ils périrent en masse durant la Shoah. Un tiers environ des victimes de la Solution finale en France étaient d’origine polonaise. à la Libération, les survivants furent bient t rejoints par de nouveaux réfugiés, rescapés des ghettos et des camps, aux yeux desquels la Pologne n’était plus qu’un immense cimetière. Durant plus de quarante ans, le partage de l’Europe en deux blocs antagonistes acheva de les couper de leur pays d’origine. Aucun, ou presque, n’apprit le polonais à ses enfants. Tous, en revanche, déployèrent d’importants efforts pour s’intégrer à leur société d’accueil et devenir Fran ais. Comparer leurs trajectoires individuelles offre une double perspective riche d’enseignements sur l’immigration en France et le destin des Juifs au xxe siècle. A lot of Polish Jews, fleeing misery and anti-Semitism, settled in France before the Second World War. In 1940, the German occupation and the establishment of the Vichy regime ended their hopes of integration. Filed, despoiled, rounded up, deported, they massively died during the Holocaust. One third of the victims of the “Final Solution” in France came from Poland. At the Liberation, new refugees, survivors from ghettos and camps, arrived. For them, Poland was just a huge cemetery. Hardly anyone of them spoke Polish with his children. On the other hand, they made important efforts to integrate French society and to become French citizens. To compare their individual trajectories gives a double viewpoint on the immigration in France and the fate of Jews during the twentieth century.
Energy Stability in a High Intensity Pulsed SC Proton Linac
Alban Mosnier
Physics , 2000,
Abstract: Spallation source dedicated for neutron scattering experiments, as well as multi-purpose facilities serving several applications call for pulsed mode operation of a high intensity proton linac. There is general agreement on the superconducting technology for the high-energy part, which offers some advantages, like higher gradient capabilities or operational costs reduction, as compared to room-temperatures accelerating structures. This mode of operation however could spoil the energy stability of the proton beam and needs thus to be carefully studied. First, transient beam-loading effects, arising from the large beam phase slippage along a multi-cell cavity and associated with the finite RF energy propagation, can induce significant energy modulation with a too small cell-to-cell coupling or a too large number of cells. Second, due to beam phase slippage effects along the linac, energy spread exhibits a larger sensitivity to cavity fields fluctuations than relativistic particles. A computer code, initially developed for electron beams has been extended to proton beams. It solves the 6xN coupled differential equations, needed to describe cavity fields and beam-cavity interactions of a high-energy linac composed of N cavities. Simulation examples on a typical pulsed accelerator are given with various error sources, like Lorentz forces or microphonics detuning, beam injection energy offsets, intensity jitters ...
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