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Search Results: 1 - 10 of 18552 matches for " Al-Okbi "
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Preparation and evaluation of functional foods in adjuvant arthritis
Al-Okbi, S. Y.,Mohamed, D. A.
Grasas y Aceites , 2012, DOI: 10.3989/gya.130811
Abstract: Adjuvant arthritis is an animal model that closely resembles rheumatoid arthritis in humans. It is a successful working model used to study new anti-inflammatory agents. In previous studies (animal and clinical) we have shown that evening primrose oil, fish oil and the methanol extract of date fruits and fenugreek seeds have anti-inflammatory activity and that the methanol extract of dates has an antioxidant effect. Based on these studies, the aim of the present study was to prepare 7 functional foods containing such bioactive fractions separately or in combination and to evaluate them in adjuvant arthritis in rats, study the stability of bioactive ingredients and evaluate their sensory properties. The studied biochemical parameters were erythrocyte sedimentation rate, erythrocyte superoxide dismutase, glutathione peroxidase and plasma copper, zinc and interlukin 2. Nutritional parameters, including body weight gain, food intake and food efficiency ratio were monitored during the feeding of the functional foods. The bioactive ingredients assessed were total phenolic contents and fatty acids. The results showed improvement in the biochemical parameters, body weight gain and food efficiency ratio of arthritic rats fed on the functional foods with different degrees. All the prepared functional foods were sensory accepted. The active ingredients showed stability during storage. In conclusion, all the tested functional foods showed promising antiinflammatory activity and were determined to be acceptable through sensory evaluation which means that their potential beneficial use as dietary supplements in rheumatoid arthritis patients may be recommended. La artritis adyuvante es un modelo utilizado en animales y se caracteriza por ser muy parecida a la artritis reumatoide en humanos. Se trata de un modelo de trabajo utilizado con éxito para estudiar nuevos agentes anti-inflamatorios. En estudios previos (animales y clínica) hemos demostrado que el aceite de onagra, el aceite de pescado y los extractos metanólicos de semillas de fenogreco o alholva y de dátiles tienen actividad anti-inflamatoria y que el extracto metanólico de dátiles tiene efecto antioxidante. Basado en estos estudios, el objetivo del presente trabajo consistió en preparar alimentos funcionales con siete fracciones bioactivas por separado y conjuntamente y evaluarlas en artritis adyuvante en ratas, estudiar la estabilidad de los principios bioactivos y evaluar sus propiedades sensoriales. Los parámetros bioquímicas estudiados fueron la velocidad de sedimentación globular, la enzima superóxido di
Therapeutic Diets for Diarrhea: Biological Evaluation in Rats
Thanaa E. Hamed,Afaf Ezzat,Sahar Y. Al-Okbi
Pakistan Journal of Biological Sciences , 2003,
Abstract: The present research dealt with the evaluation of the anti-diarrheal activity of two therapeutic diets in model of castor oil induced diarrhea in rats. Formula I contain modest amount of skimmed milk, formula II was lactose restricted diet. Both formulae contain cereals, legumes, honey and edible source having anti-diarrheal activity. The nutritional value of the two formulated therapeutic diets was evaluated in normal growing rats in comparison to reference formula, milupa special formula, in addition to control balanced diet (contain 10% protein supplemented from casein). The evaluation of nutritional value depended on determination of total food intake, body weight gain, food efficiency ratio and protein efficiency ratio. Nutritional status of rats fed different diets was also evaluated through determination of certain biochemical parameters such as percentage haematocrit, blood haemoglobin concentration, plasma total protein, albumin, iron, phosphorus, zinc, magnesium, retinol and -carotene. Results showed that anti-diarrheal activity of formula I was superior compared to formula II. Milupa and formula I have higher values of protein efficiency ratio and food efficiency ratio than control casein diet which were significant in case of Milupa. However diet II showed comparable values to control. Biochemical parameters showed higher values of plasma total protein, magnesium and retinol of rats fed Milupa diet. Feeding diet II produced significant increase of plasma iron magnesium and retinol. However, only significant increase of plasma magnesium has been observed when feeding diet I.
Reduction in hypercholesterolemia and risk of cardiovascular diseases by mixtures of plant food extract: a study on plasma lipid profile, oxidative stress and testosterone in rats
Mohamed, Doha A.,Hamed, Thanaa E.,Al-Okbi, Sahar Y.
Grasas y Aceites , 2010, DOI: 10.3989/gya.021210
Abstract: The present study was postulated to prepare and evaluate the influence of two plant food extract mixtures on plasma lipid profile, oxidative stress and testosterone levels in rats fed a hypercholesterolemic diet. The safety of the studied extract mixtures was evaluated through the determination of liver and kidney functions. The total phenolic contents, tocopherols, fatty acids and unsaponifiable matter (UNSAP) in the extract mixtures were determined. Rats fed a hypercholesterolemic diet were given a daily oral dose (300 mg/kg rat body weight) of either mixture I or II for a month and compared with a control hypercholesterolemic group and a normal control group. Results showed that α-tocopherol was 0.750 and 4.017 mg, γ-tocopherol was 0.564 mg and 0 and δ-tocopherol was 15.23mg and 0.634mg/100g for mixtures I and II, respectively. The phenolic contents in mixtures I and II were 36.74 and 23.72 g gallic acid equivalent/100g mixture, respectively. The GLC investigation of UNSAP revealed that stigmasterol and b-sitosterol were the major phytosterols in mixtures I and II, respectively followed by campesterol in both. The GLC analysis of the fatty acids showed that oleic acid was the major fatty acid in both extract mixtures. Results from the animal experiment showed that feeding a hypercholesterolemic diet produced a significant increase in total lipids, total cholesterol (T-Ch), triglycerides (TGs), low density lipoprotein cholesterol (LDLCh), T-Ch/HDL-Ch, TGs/HDL-Ch and malondialdehyde (MDA) and a significant reduction in high density lipoprotein cholesterol (HDL-Ch), vitamin E, b-carotene and testosterone. Rats fed a hypercholesterolemic diet and given mixture I or II showed significant improvements in plasma lipid profile compared to the hypercholesterolemic control group. This improvement was associated with a significant reduction in oxidative stress reflected by an elevation in plasma levels of antioxidants (vitamin E and b-carotene) and a reduction in plasma MDA levels. The plasma level of testosterone increased significantly in the rats fed the hypercholesterolemic diet and given mixture I or II compared to the hypercholesterolemic control. Plasma testosterone showed a significant negative correlation with plasma TGs and TGs/HDL-Ch in the hypercholesterolemic control rats. The studied extract mixtures showed complete safety towards liver and kidney functions. In conclusion the tested extract mixtures showed an improvement in the plasma lipid profile, a significant increase in testosterone and a decrease in oxidative stress with promising prevention
Role of Bifidobacterium bifidum and plant food extracts in improving microflora and biochemical and cytogenetic parameters in adjuvant arthritis.
Al-Okbi, S. Y.,Mohamed, D. A.,Donya, S. M.,Abd El Khalek, A. B.
Grasas y Aceites , 2011, DOI: 10.3989/gya.089810
Abstract: The aim of the present research was to discover plant food extracts and probiotics that may have bioactivity towards chronic inflammation. Three plant food extract mixtures expected to be rich in phenolic compounds, carotenoids and tocopherols were prepared. The anti-inflammatory activity of the different mixtures as well as probiotic bacteria (Bifidobacterium bifidum) were evaluated in adjuvant arthritis in rats. The anti-inflammatory effect, mechanism of action and safety of the three mixtures and Bifidobacterium bifidum were studied by measuring the size of inflammation and the determination of inflammatory and oxidative stress biomarkers, colonic bacteria profile and specific cytogenetic parameters. The contents of tocopherols, β-carotene and phenolic compounds in the mixtures were determined. The results show that the tested mixtures and Bifidobacterium bifidum possess promising anti-inflammatory effects. The mechanism of action seems to involve a reduction in oxidative stress and inflammatory biomarkers and an effect on colonic microflora. Genotoxicity and DNA fragmentation induced by adjuvant arthritis were prevented after supplementation with the tested mixtures. El objetivo de la presente investigación fue encontrar extractos de alimentos vegetales y probióticos que puedan tener bioactividad hacía la inflamación crónica. Mezclas de tres extractos de alimentos vegetales conocidos por su riqueza en compuestos fenólicos, carotenoides y tocoferoles han sido preparadas. La actividad anti-inflamatoria de las diferentes mezclas y de bacterias probióticas (Bifidobacterium bifidum) fue evaluada en artritis adyuvante en ratas. El efecto anti-inflamatorio, mecanismo de acción y salubridad de las tres mezclas y de Bifidobacterium bifidum ha sido estudiado mediante la medida del tama o de la inflamación y la determinación de biomarcadores de inflamación y estrés oxidativo, del perfil de bacterias del colón y de parámetros citogenéticos específicos. El contenido de tocoferoles, β-caroteno y compuestos fenólicos en las mezclas fue determinado. Los resultados muestran que las mezclas y los Bifidobacterium bifidum poseen un prometedor efecto anti-inflamatorio. El mecanismo de acción parece involucrar una reducción de los biomarcadores inflamatorios y del estrés oxidativo y tiene un efecto sobre la microflora del colón. La fragmentación del DNA y la genotoxicidad inducida por la artritis adjuvante fue prevenida con la suplementación de las mezclas ensayadas.
Evaluation of Serum Levels of Lipids, Minerals and Troponin T. In Acute Myocardial Infarction Patients Having Different Ages
T. K. Motawi,O. El Ahmady,Sahar Y. Al. Okbi,O. M. Metwalli
Pakistan Journal of Biological Sciences , 2001,
Abstract: The present work was postulated to study serum lipids, minerals and troponin T. (TnT), minerals on the seventh day of infarction in acute myocardial infarction (AMI) patients having different ages. Three age groups of both patients and control were established where the age ranged from 25-40 years ( group 1), 41-50 years ( group 2) and > 50 years (group 3). The data of patients were compared with their age matched control groups. Results showed that serum levels of tricaylglycerols (TG) were significantly higher in groups (1) and (2) than corresponding controls. On the other hand, serum high density lipoprotein cholesterol (HDL-Ch) levels were significantly low in groups (1) and (2). Serum low density lipoprotein cholesterol (LDL-Ch) was significantly high in group(2). Concerning minerals, serum copper levels were significantly high in groups (2) and (3). Also, serum zinc level was significantly high in group (3). Both serum magnesium and iron failed to show any significant changes. Serum TnT showed an extreme increase in patients when compared with the control subjects. Questionnaire for cigarette smoking, alcohol consumption, coffee drinking and type of fat eaten was recorded for each patient and control subject.
Induction of Labor with PGE2 after One Previous Cesarean Section: 18 Years Experience in a University Hospital  [PDF]
Nourah Al Qahtani, Sameera Al Borshaid, Hissa Al Enezi
International Journal of Clinical Medicine (IJCM) , 2011, DOI: 10.4236/ijcm.2011.21008
Abstract: Objective: To review the outcome of prostaglandin induction of labor in term pregnant women with previous one ce-sarean section compared to those without previous Cesarean section. Design: 18 years retrospective review of hospital records and case note review of index cases. Setting: University hospital. Population: Three hundred and twenty two women who had their labor induced with prostaglandin E2. One hundred and sixty one women had one previous Ce-sarean section. Methods: This study was conducted at King Fahad University Hospital, University of Dammam. It is a tertiary referral center with approximately 2300 births per year. We searched the hospital's records of deliveries from January 1992 to December 2009 and reviewed all indications and outcomes of prostaglandin induction of labor in women with one previous Cesarean section. The control group was composed of women who had their labor induced with prostaglandin but without previous Cesarean section. Main outcome measures: Labor outcome and uterine rup-ture Results: Three hundred and twenty two women were included. All received prostaglandin E2 for induction of labor. One hundred and sixty one women had one previous Cesarean section (study group) and the rest had no previous Ce-sarean section (control group). There was no difference in the rate of vaginal delivery between study and control group, 68.3% and 79.5% (p value 0.3), respectively. The rate of uterine rupture was 30 times higher in study group (2.5% Vs 0.033%). Conclusion: In women with one previous Cesarean section, induction of labor with prostaglandin leads to comparable rate of vaginal delivery similar to those without prior Cesarean section but with relatively high risk of uter-ine rupture.
Assessment of Gaseous and Particulate Pollutants in the Ambient Air in Al Mirfa City, United Arab Emirates  [PDF]
Entisar Al Katheeri, Fadi Al Jallad, Muthanna Al Omar
Journal of Environmental Protection (JEP) , 2012, DOI: 10.4236/jep.2012.37077
Abstract: From 2007-2009, National Energy and Water Research Center (NEWRC) on behalf of Abu Dhabi Water and Electricity Authority (ADWEA) conducted a long term baseline study of nitrogen dioxide (NO2), carbon monoxide (CO), sulfur dioxide (SO2), ozone (O3) and particulate matter <10 μm in diameter (PM10) using ambient air quality station located in the vicinity of Al Mirfa power plant in Abu Dhabi, United Arab Emirates (UAE).The objective of this study was to establish baseline levels and study the behavior of airborne pollutants from natural as well as anthropogenic origins with temporal variations. The study reveals that the average hourly values for NO2, SO2, and 8 hour average of CO were within the acceptable levels of 400, 300 and 30,000 μg/m3 respectively, whereas the levels of O3 as 8 hour average (<200 μg/Nm3) and PM10 (<150 μg/Nm3) occasionally exceeded the FEA permissible limits during the study period. Seasonal variation based on three years data reveals that the highest concentration of NO2 and SO2 were during winter and for CO and O3 during summer months. Results indicate that the levels of SO2 and CO were significantly controlled and improved while the fuel combustion of Al Mirfa power plant had increased from 2007 to 2009. Dust has significantly impact on the air quality by elevated levels of PM10 exceed in several instances associated with regional sand- storm during the monitoring period.
Three-Dimensional Scenes Restore Using Digital Image  [PDF]
Takialddin Al Smadi, Igried Al-Khawaldeh, Kalid Al Smadi
Journal of Signal and Information Processing (JSIP) , 2017, DOI: 10.4236/jsip.2017.81001
Abstract: Encryption and decryption method of three-dimensional objects uses holograms computer-generated and suggests encoding stage. Information obtained amplitude and phase of a three-dimensional object using mathematically stage transforms overlap stored on a digital computer. Different three-dimensional images restore and develop the system for the expansion of the three-dimensional scenes and camera movement parameters. This article talks about these kinds of digital image processing algorithms as the reconstruction of three-dimensional model of the scene. In the present state, many such algorithms need to be improved in this paper proposing one of the options to improve the accuracy of such reconstruction.
Syed Ghulam Shabbir (1923-2002) and His Syndrome  [PDF]
Khalid Al Aboud, Daifullah Al Aboud
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2011, DOI: 10.4236/jcdsa.2011.12007
Abstract: Professor Syed Ghulam Shabbir (1923-2002), is one of the Pakistani well-known dermatologists. In 1986, Shabbir and his colleagues described a novel autosomal recessive syndrome, which they called laryngoonychocutaneous syndrome. They reported this condition, in 22 patients in 12 families living in Lahore, Pakistan. This syndrome is characterized by cutaneous erosions, nail dystrophy and exuberant vascular granulation tissue in certain epithelia, especially conjunctiva and larynx. This report sheds light on Shabbir and the syndrome that bears his name.
Geomatics for Rehabilitation of Mining Area in Mahis, Jordan  [PDF]
Rami Al-Ruzouq, Samih Al Rawashdeh
Journal of Geographic Information System (JGIS) , 2014, DOI: 10.4236/jgis.2014.62014
Abstract:

Mining activities often cause dramatic changes in landscapes, particularly in the dump sites and its surrounding environment. Land rehabilitation is the process of renovating damaged land to some extent of its original shape and aims to minimize and mitigate the environmental effects to allow new land uses. The success of different rehabilitation strategy and newly suggested urban and architecture modeling depends on the landscape characterization (topography of the study area and its derivatives such as slope and aspects, geological and geomorphologic nature of the study area). The aim of this study is to demonstrate the utility of different methodologies based on geomatics techniques (Photogrammetry, Remote Sensing, Global Positioning System (GPS) and three dimensional Geographic Information System (GIS)) for highlighting landscape characterization which is needed for rehabilitation of Mahis area. Photogrammetric adjustment procedures were used to create digital elevation model and Orth-Photo model for the study area using aerial images. Remote sensing data were used for land classification to provide vital information for rehabilitation planning. GPS field observations were used to build spatial network for the study area based on ground control point collections. Finally, realistic representation of the study area with three dimensional GIS was prepared for the study area considering ease and flexible updating of the geo-spatial database.

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