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Search Results: 1 - 10 of 8372 matches for " Akila Victor "
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Akila Victor
International Journal on Computer Science and Engineering , 2010,
Abstract: The main key point of preferential image segmentation is to segment object of user interest based on intensities, boundaries and texture and ignoring the remaining portions. It explains the trees of shapes torepresent image content. In the tree of shape we use algorithms called as FLLT (Fast Level Line Transform) and JSEG (Jsegmentation). Here both the algorithm are compared and an analysis is done to display the result of objects selected from prior images.
The nature of proteins in influenza  [PDF]
K. Akila, P. Balamurugan, E. Rajasekaran
Health (Health) , 2012, DOI: 10.4236/health.2012.430151
Abstract: Mutation can alter the structure of viral proteins to form different structure. Carbon distribution is responsible for these changes in structure. The carbon distribution in proteins of human Influenza A virus is analyzed here. Results reveal that the carbon contents are high in surface proteins, optimum in polymerase proteins and less in nuclear proteins. Polymerase proteins have better carbon distribution pattern than the other proteins. Thymine distribution in different frames of mRNAs are checked as it has link with carbon distribution pattern in the corresponding proteins. Results show that frame 4 is violating from thymine distribution. This is responsible for production of protein with different carbon distribution. Unusual thymine distribution in frame 3 are observed. The thymine distributions are different in viral mRNA compared to normal one. Minimizing the excess thymine in H1N1 mRNAs might improve the protein performance. Mutational study based on carbon distribution should be better exploited for further improving the protein stability, activity and ultimately for gene therapy.
Isoniazid and Rifampicin as Therapeutic Regimen in the Current Era: A Review  [PDF]
Sulochana Somasundaram, Akila Ram, Laavanya Sankaranarayanan
Journal of Tuberculosis Research (JTR) , 2014, DOI: 10.4236/jtr.2014.21005
Abstract: Tuberculosis represents one of the biggest challenges in the medical field. According to World Health Organization (WHO) Global Tuberculosis Report, 2012, there were estimated 8.7 million new TB cases worldwide while 1.4 million people died of TB. Additionally, 90% of the cases of TB are reported in developing countries, with India having the largest number of incident cases. The current treatment method includes the administration of a cocktail of drugs which includes Isoniazid (INH), Rifampicin (RIF), Ethambutol (EMB) and Pyrazinamide (PZA) which are referred to as the first line of drugs. Isoniazid and Rifampicin are currently the two most powerful anti-TB medications. The occurrences of multi-drug and extensive-drug resistant strains (MDR-TB and XDR-TB, respectively) have become a global concern and pose a serious challenge for public health management. Treatment of these resistant cases involves the usage of the second line of anti-tuberculosis drugs which are less effective than the first line and are known to cause adverse reactions or toxic side-effects. Tuberculosis research should not only focus on treatment methods but also on management of the current cases of resistance and measures to prevent an outbreak of resistant TB infection. This review outlines the mechanism of action of isoniazid and rifampicin and how resistance to these drugs emerges. We also provide a brief insight into the prevalence of HIV in TB patients and the challenges associated with treatment regimens in this co-infection.
Contribution to Definition of a Structured Design Methodology of Mixed Circuit
Akila Zouyed,Assia Khoualdia
Asian Journal of Information Technology , 2012,
Abstract: This research concerns a set of proposals in order to structuring the design of MOS analog VLSI. They are derived from structured logic design methods, which have shown their great efficiency. We propose, by using NMOS inverter as linear amplifier, a simple method to go from functional to structural description. So it was possible to confirm that the designed circuit will work exactly as it was predicted by functional simulation results. This method has been, successfully and efficiently applied to the design of a PLL.
Evaluation of oral ulcers appearing in pemphigus patients treated with dexamethasone-cyclophosphamide pulse therapy
Pasricha J,Kapasi Akila
Indian Journal of Dermatology, Venereology and Leprology , 1992,
Abstract: Twenty cases of pemphigus with oral ulcers who were being treated with dexamethasone-cyclophosphamide pulse therapy were evaluated for the cause of ulcers. The lesions were first classified into pemphigus ulcers, aphthous ulcers, pyogenic infection and candidiasis on the basis of clinical characteristics. Smears from these ulcers were then stained with Giemsa stain to look for acantholytic cells and bacteria. Another smear was mounted in 10% KOH to look for candida. Seven patients were clinically diagnosed to have pemphigus ulcers, but acantholytic cells were seen in only 2 cases. Both these patients had superadded infection with candida and gram positive bacteria respectively. Of the 9 cases clinically diagnosed to have candidiasis, only 6 revealed candida in 10% KOH smears, while 1 patient revealed acantholytic cells. All the 3 cases clinically considered to have aphthous ulcers, revealed only normal looking epithelial cells. One patient clinically diagnosed to have pyogenic infection revealed pus cells and bacteria on gram stain. It is obvious that oral ulcers in a pemphigus patient may not always be pemphigus ulcers, and some of these may be super-infected with candida, pyogenic or other organisms. A proper evaluation is therefore necessary for appropriate treatment.
What Might be the Difference in Viral Proteins?
Akila K.,Rajasekaran E.
International Journal of Bioinformatics Research , 2009,
Abstract: The difference between normal and viral proteins is the way the amino acids organized in someform. Though both proteins use same 20 naturally occurring amino acids, it differs in arrangements. Thisdifference cannot be felt by merely comparing the amino acid sequence but at atom level. This is analysedand compared in terms of carbon distribution as carbon is the only element that contributes towards thedominant force, hydrophobic interaction. For this purpose the arenaviruses have been selected here forstudy. The protein sequences of 7 arenaviruses are analysed. Our results show that the carbon distributionin viral proteins is different from the normal proteins. Either the carbon content is different or the distributionis not uniform. This carbon distribution analysis uses our earlier report of 31.44% of carbon for its structureand activity.
B. Akila* and K. Manickavasakam
International Journal of Pharmaceutical Sciences and Research , 2013,
Abstract: In Siddha system of medicine, the two formulations Vedikara silasathu parpam and Nerunjil kudineer in combination is given for urinary tract infection. Inhibition in the synthesis of inflammatory mediators and prostaglandins owe to the anti- inflammatory and antinociceptive properties of the drugs. In this study, the two Siddha formulations VSP and NK in combination was evaluated for anti- inflammatory activity by means of carrageenan induced rat paw edema method and antinociceptive activity with tail flick method in Wistar albino rats. In the carrageenan induced paw edema technique, rats at the dosage of 500mg/kg/p.o of VSP and NK, significant (p<0.001) inhibition of inflammatory progression was observed than the control group. In the tail flick method, VSP and NK at dosage of 500 mg dose, increased the tail withdrawal time significantly (p<0.001) when compared to the control group. This study had established the significant anti- inflammatory and antinociceptive activity of VSP and NK.
Spectral statistics of nearly unidirectional quantum graphs
Maram Akila,Boris Gutkin
Mathematics , 2015, DOI: 10.1088/1751-8113/48/34/345101
Abstract: The energy levels of a quantum graph with time reversal symmetry and unidirectional classical dynamics are doubly degenerate and obey the spectral statistics of the Gaussian Unitary Ensemble. These degeneracies, however, are lifted when the unidirectionality is broken in one of the graph's vertices by a singular perturbation. Based on a Random Matrix model we derive an analytic expression for the nearest neighbour distribution between energy levels of such systems. As we demonstrate the result agrees excellently with the actual statistics for graphs with a uniform distribution of eigenfunctions. Yet, it exhibits quite substantial deviations for classes of graphs which show strong scarring.
Methane Steam Reforming on Supported Nickel Based Catalysts. Effect of Oxide ZrO2, La2O3 and Nickel Composition  [PDF]
Akila Belhadi, Mohamed Trari, Chérifa Rabia, Ouiza Cherifi
Open Journal of Physical Chemistry (OJPC) , 2013, DOI: 10.4236/ojpc.2013.32011

The catalytic properties of Ni (4 and 10 wt%) supported on both La2O3 and ZrO2 were investigated for the methane steam reforming reaction between 475 and 700 at atmospheric pressure. The catalysts were prepared by the impregnation method and characterized by several techniques (atomic absorption, BET method, X-ray diffraction and TG-TPO). The catalytic activity of Ni/support systems strongly depends on both of the nature and physico-chemical properties of the support. No deactivation was observed in catalytic systems, whatever the reaction temperature indicating high stability of the catalyst.

Development of Alkylation Toluene with Methanol for Fuel on Modified ZSM-5 Zeolites by Amphoteric Surfactant  [PDF]
Akila El Morsi, A. M. A. Omar, Nora Y. Almehbad
Journal of Surface Engineered Materials and Advanced Technology (JSEMAT) , 2014, DOI: 10.4236/jsemat.2014.41007

Methylation of toluene over ZSM-5 zeolites modified by the introduction of Sr of 2.5%, 5%, and 10% by weight was studied. Experiments were performed in a fixed bed under the conditions of reaction temperatures between 300°C-500°C, liquid hour space velocity of 4 g toluene/h.g catalyst, methanol to toluene ratio 4:1, and 0.01% of N-Octyl-N-benzyl-N-methylglycine as emulsifier. Data for conversion of toluene and selectivity towards xylene isomers showed that 2.5% Sr/ZSM-5 catalyst has the highest conversion of toluene at 500°C, and the lowest p-xylene selectivity, while 10% Sr/ZSM-5 catalyst has the highest selectivity for p-xylene production. Nevertheless, the catalyst 2.5% Sr/ZSM-5 has the highest selectivity for m-xylene. The two catalysts 2.5% and 5% Sr/ZSM-5 give nearly the same selectivity for the three xylene isomers at all conversions obtained at the reaction conditions under study.

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