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Search Results: 1 - 10 of 602 matches for " Agata Smoleń "
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Effects of vitamin D3 on selected biochemical parameters of nutritional status, inflammation, and cardiovascular disease in patients undergoing long term hemodialysis
Anna Bednarek?Skublewska,Agata Smoleń,Andrzej Jaroszyński,Wojciech Za?uska
Polish Archives of Internal Medicine , 2010,
Abstract: INTRODUCTION: Vitamin D3 has diverse biological effects extending beyond the maintenance of calcium and phosphorus homeostasis and ensuring the proper functioning of the body. OBJECTIVES: This study evaluated the levels of vitamin D3 and its association with nutritional status, immunological activity, and selected markers of cardiovascular disease in patients on long term hemodialysis (HD). PATIENTS AND METHODS: We measured 25 hydroxyvitamin D3 (25(OH)D3) levels in a group of 84 patients (mean age, 65 years; average time on dialysis, 32.5 months) and investigated correlations between 25(OH)D3 levels and the following parameters: albumin, body mass index, hemoglobin (Hb), interleukin 6 (IL 6), interleukin 10, C reactive protein, asymmetric dimethylarginine (ADMA), N terminal pro B type natriuretic peptide (NT proBNP), and comorbidity score. RESULTS: A mean 25(OH)D3 level was 15.4 ±7.2 ng/ml and only 5% of patients had 25(OH)D3 levels above the normal value of 30 ng/ml. There was no statistically significant difference in 25(OH)D3 levels between women and men (P = 0.06). A negative correlation was observed between 25(OH)D3 and IL 6 (R = –0.31, P = 0.009) and ADMA (R = –0.26, P = 0.03), as well as a positive correlation between 25(OH)D3 and Hb (R= 0.21, P = 0.05). There was no association between 25(OH)D3 levels and nutritional status. CONCLUSIONS: A significant vitamin D3 deficiency observed in the majority of patients undergoing long term HD contributes to the development of chronic inflammation, anemia, and indirectly, to endothelial cell injury.
Usefulness and efficiency of formalin-fixed paraffin-embedded specimens from laryngeal squamous cell carcinoma in HPV detection by IHC and PCR/DEIA.
Kamal Morshed,Ma?gorzata Polz-Dacewicz,Marcin Szymański,Agata Smoleń
Folia Histochemica et Cytobiologica , 2010, DOI: 10.5603/4215
Abstract: The use of formalin-fixed paraffin-embedded (FFPE) tissues for HPV DNA detection by PCR from biopsy materials is not entirely clear in retrospective studies. The aim of our study was to evaluate the usefulness and efficiency of FFPE tissues from laryngeal cancer (LSCC) in HPV detection by immunohistochemistry reaction (IHC) and PCR-DNA enzyme immunoassay method (PCR/DEIA) and to compare with HPV detection from DFT. HPV-DNA was amplified from 54 FFPE tissues from LSCC specimens by the short PCR fragment (SPF10) primer set using PCR/DNA method and monoclonal anti Human Papillomavirus antibodies in IHC. In the same patients 54 specimens were collected and immediately deep-frozen and stored at (-70 °C) to (-80 °C). All the FFPE and deep-frozen tissue (DFT) specimens were positive for -globin amplification. HPV was detected by two methods (SPF10 PCR/DEIA and IHC) in 14 (25.92%) out of 54 specimens from FFPE. Significant differences were found between the HPV detection using PCR/DEIA method and IHC method in FFPE tissues. The comparative analysis of the 54 samples after assuming PCR method in FFPE tissues showed accuracy of 92.6%, sensitivity of 90.5% and specificity of 93.9%. The FFPE tissues method has high sensitivity, specificity and accuracy when used to detect HPV DNA by PCR reaction and it is comparable to DFT results. DNA quality of FFPE samples is adequate and it can be used in HPV-DNA detection and in retrospective studies on LSCC.
Soft power w polityce zagranicznej Turcji wobec regionu Bliskiego Wschodu
Kinga Smoleń
Annales UMCS, Sectio K (Politologia) , 2011, DOI: 10.2478/v10226-011-0005-3
Abstract: The subject of analysis in the article is soft power in the foreign policy of Turkey towards the Region of Middle East. In the conditions of the parameter change of the international system and in particular, appearance of new outside-state subjects and new quality phenomena and dangers, soft power has become an effective instrument enabling states to affect the external system as well as realization of the aims of foreign policy. Soft power model in Turkey's foreign policy towards Middle East is conditioned by internal factors: dynamically developing economy, access to energetic resources and internal factors such as geopolitical location and current shape of the international system. Realization of soft power in Turkey's foreign policy towards the Middle East region is accomplished, among others, through mediation in local conflicts, political and economic cooperation, propagating principles of liberal economy and democracy, promotion of culture and fostering the civil society. Analyzing effectiveness of soft power in Turkey's foreign policy towards the Middle East region, the author has concluded that this model is "the catalyst" of the regional cooperation and of civil society development as well as an effective tool of state image promotion abroad. However, it is not a sufficient tool of extinguishing international conflicts.
VideoCar in finan ne plati zajema cestnih podatkov v ob inah : VideoCar and the Financial Aspects of Community Road-Data Acquisition
Domen Smole
Geodetski Vestnik , 2003,
Abstract: In the article there are two (often overlooked) aspects laid out regarding the important role and the influence of geodesy on the life of communities. First, the possibilities enabling communities to improve their financial management are emphasized. Such possibilities are often based on unbiased real-estate listings which can be provided by geodesy. The other type of communication between a community and geodesy is imposed by the law and as such supports communities in their efforts to reach the aims outlined by their spatial planning and managament departments.
Changes in the Classroom: Accomplishments and Obstacles of an Innovative Proposal in the View of Teachers  [PDF]
Letícia Portieri Monteiro, Katia Stocco Smole
Creative Education (CE) , 2014, DOI: 10.4236/ce.2014.52011

In 1999, the Judaic Education Council of Rio de Janeiro implemented the Educational Innovation Program (EIP) in the Israeli schools of that city so as to meet the new trends in Brazilian education. The present work was designed to evaluate the modifications taking place in the school environment as a result of EIP implementation, a program whose core idea is to work on knowledge building from the Piagetian perspective, active learning in Dewey’s conception, and multiple intelligences as presented by Gardner. In order to assess the chosen program, we used a qualitative approach through semi-structured interviews with the participants and observation of classrooms from the first to the fifth grade of elementary school. The results of our study showed that from the implementation of the program, the professionals involved were more motivated to search for information and update their knowledge so as to meet the differences between students, using a diversity of strategies and dynamic activities which led to encouraging student autonomy as regards their learning. The reported difficulties for the work to proceed were mainly about the schoolwork timetable planned for both the project and the subjects, and teachers having to cover an extensive curriculum, common to other Brazilian schools. In every innovative program, it is important for the professionals involved in it to continually re-evaluate its development, searching for changes or alternatives as difficulties are encountered. The aim of the present paper is to report the main findings of this research, as well as indicate the strengths and precautions to take in educational innovation proposals whose primary focus is classroom innovation.

Susceptibility of Staphylococcus aureus Clinical Isolates to Propolis Extract Alone or in Combination with Antimicrobial Drugs
Robert D. Wojtyczka,Arkadiusz Dziedzic,Danuta Idzik,Ma?gorzata K?pa,Robert Kubina,Agata Kaba?a-Dzik,Joanna Smoleń-Dzirba,Jerzy Stojko,Mieczys?aw Sajewicz,Tomasz J. W?sik
Molecules , 2013, DOI: 10.3390/molecules18089623
Abstract: The objective of this study was to assess in vitro the antimicrobial activity of ethanolic extract of Polish propolis (EEPP) against methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) clinical isolates. The combined effect of EEPP and 10 selected antistaphylococcal drugs on S. aureus clinical cultures was also investigated. EEPP composition was analyzed by a High Performance Liquid Chromatography (HPLC) method. The flavonoid compounds identified in Polish Propolis included flavones, flavonones, flavonolols, flavonols and phenolic acids. EEPP displayed varying effectiveness against twelve S. aureus strains, with minimal inhibitory concentration (MIC) within the range from 0.39 to 0.78 mg/mL, determined by broth microdilution method. The average MIC was 0.54 ± 0.22 mg/mL, while calculated MIC 50 and MIC 90 were 0.39 mg/mL and 0.78 mg/mL, respectively. The minimum bactericidal concentration (MBC) of the EEPP ranged from 0.78 to 3.13 mg/mL. The in vitro combined effect of EEPP and 10 antibacterial drugs was investigated using disk diffusion method-based assay. Addition of EEPP to cefoxitin (FOX), clindamycin (DA), tetracycline (TE), tobramycin (TOB), linezolid (LIN), trimethoprim+sulfamethoxazole (SXT), penicillin (P), erythromycin (E) regimen, yielded stronger, cumulative antimicrobial effect, against all tested S. aureus strains than EEPP and chemotherapeutics alone. In the case of ciprofloxacin (CIP) and chloramphenicol (C) no synergism with EEPP was observed.
Molecular Phylogeny and Estimated Time of Divergence in the Central European Melanopsidae: Melanopsis, Fagotia and Holandriana (Mollusca: Gastropoda: Cerithioidea)
Marcin Smoleń , Andrzej Falniowski
Folia Malacologica , 2009, DOI: 10.2478/v10125-009-0001-4
Abstract: Three European melanopsids: Melanopsis parreyssii (Philippi, 1847) from Ochiul Mare (Romania), Fagotia acicularis (A. Férussac, 1828) from a spring near Crisul Negru (Romania), and Holandriana holandri (C. Pfeiffer, 1828) from Lake Skutari (Montenegro), as well as Melanopsis costata Oliver, 1804 from Iraq, are considered is this paper. Eight partial sequences of ribosomal 18S, and seven of mitochondrial COI were analysed. Maximum likelihood trees based on 18S confirm the placement of the Melanopsidae within the Cerithioidea, as well as the monophyly of the latter group. The COI-based tree confirms the placement of the Melanopsidae within the Cerithioidea, but does not confirm the monophyly of either Melanopsidae or Cerithioidea. The results suggest that Fagotia should be synonymised with Melanopsis, Holandriana is a distinct genus, and Melanopsis costata is not congeneric with M. parreyssii. The application of molecular clock, with one point calibration for COI for the Hydrobiidae, estimated the times of divergence as 2.53±0.56 Mya for M. parreyssii and F. acicularis, 9.49±1.67 Mya for M. parreyssii and H. holandri, and 10.71±1.88 Mya for F. acicularis and H. holandrii. 2.5 Mya coincides with the beginning of the glacial period in Europe, and 8-12 Mya was the time when Lake Pannon covered the largest area.
Optimization of organization and access to basic spatial data
Rada Rikanovi?,Domen Smole
Geologija , 2005,
Abstract: Geologic Survey of Slovenia acquired, in the last few years numerous digital spatial data of various sources and scales. Amounts of data constantly increased which lead to considerations on their organization in a unique collection to which the users could havedirect access. For surveying the already organized spatial data the ESRI ArcIMS program was selected, whereas for organization of spatial data themselves and for certain specific users requirements (cropping of raster data to a selected domain) the mentioned GIS internet solution had to be upgraded with additional program modules. In the following paper factual internet GIS solutions shall be presented especially from the aspect of simplification and increased efficiency of existing working procedures.
CdSe/ZnSe quantum dot with a single Mn$^{2+}$ ion - a new system for a single spin manipulation
Tomasz Smoleński
Physics , 2014, DOI: 10.1063/1.4913831
Abstract: We present a magneto-optical study of individual self-assembled CdSe/ZnSe quantum dots doped with single Mn$^{2+}$ ions. Properties of the studied dots are analyzed analogously to more explored system of Mn-doped CdTe/ZnTe dots. Characteristic sixfold splitting of the neutral exciton emission line as well as its evolution in the magnetic field are described using a spin Hamiltonian model. Dynamics of both exciton recombination and Mn$^{2+}$ spin relaxation are extracted from a series of time-resolved experiments. Presence of a single dopant is shown not to affect the average excitonic lifetime measured for a number of nonmagnetic and Mn-doped dots. On the other hand, non-resonant pumping is demonstrated to depolarize the Mn$^{2+}$ spin in a quantum dot placed in external magnetic field. This effect is utilized to determine the ion spin relaxation time in the dark.
The Effect of Foliar Nutrition with Urea, Molybdenum, Sucrose and Benzyladenine on Yield and Some Organic Compounds of Carrot Storage Roots
Sylwester Smoleń, W odzimierz Sady
Vegetable Crops Research Bulletin , 2010, DOI: 10.2478/v10032-010-0009-8
Abstract: The Kazan F1 carrot was cultivated in years 2004-2005 in open-work containers sized 60×40×20 cm filled in with silt loam and located on the open field under shade providing fabric. The following combinations of experiments were arranged: (1) control - without foliar nutrition, and foliar nutrition with: (2) urea, (3) solution of urea+Mo, (4) urea+Mo+BA (benzyladenine BA), (5) urea+Mo+BA+sucrose, (6) BA in the concentration of 5 mg·dm-3 and (7) BA in the concentration of 10 mg·dm-3. In combinations 2-5 the following concentrations of components in solutions were applied: urea and sucrose each in 20 g·dm-3, molybdenum 1 mg·dm-3, benzyladenine 5 mg·dm-3. Foliar nutrition was applied three times. In both years of study the greatest mass of storage roots and whole plant (haulm + root) was determined after spraying with benzyladenine in 5 mg·dm-3 concentration. Plants with urea+Mo+BA+sucrose foliar nutrition were characterized by a comparable mass of roots and whole plant but only in 2005. In both years of study plants treated with urea only had the lowest root mass and the highest content of phenolic compounds and the lowest (in 2004 and the means from 2004-2005) content of soluble sugars in roots. Foliar nutrition with urea+Mo+BA+sucrose and spraying with benzyladenine exclusively in both applied concentrations caused a significant increase in the content of sugars (in 2004 and the means from 2004-2005) as well as carotenoids (except for combination no. 7 - in 2005 and the means from 2004-2005) in storage roots.
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