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Search Results: 1 - 10 of 363299 matches for " Adriana del S; Solano-González "
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Exposición al plomo y su relación con el tiempo requerido para embarazo
Guerra-Tamayo,Juan Luis; Hernández-Cadena,Leticia; Téllez-Rojo,Martha María; Mercado-García,Adriana del S; Solano-González,Maritsa; Hernández-Avila,Mauricio; Hu,Howard;
Salud Pública de México , 2003, DOI: 10.1590/S0036-36342003000800004
Abstract: objective: to determine the effects of lead exposure on the time elapsed to become pregnant. material and methods: the study population consisted of 142 women residing in mexico city between 1997 and 2001, who were already participating in a study to evaluate effects of lead exposure on reproductive health. measurements of lead in bone were performed when women were first admitted to the program. information on lead exposure and other variables of interest was obtained through a questionnaire. participants were followed up to assess the relationship between the time required to become pregnant and lead exposure. statistical analysis consisted of kaplan-meier estimates and cox proportional hazards models. results: of the total number of women in the program, 42 got pregnant: 34 before the first year of follow-up, and 8 at a later date. the mean value for lead concentration in blood was 9.3 μg/dl. the mean values for lead concentration in patella and tibia were 16.0 y 11.0 μg pb/g of bone, respectively. survival analysis was performed and no differences were detected in blood lead levels and time to pregnancy in the first year. nevertheless, in women with blood lead levels above 10.0 μg/dl, the likelihood of not achieving pregnancy was five times higher (95% confidence interval [ci] 0.05-0.56) after one year of follow-up compared with women with blood lead levels below 10.0 μg/dl. conclusions: exposure to high lead concentrations may be an important risk factor influencing the time period for a woman to get pregnant, especially in fertile women who have tried to get pregnant for more than a year.
Consumo de alimentos y asma en ni?os escolares de Cuernavaca
Gutiérrez-Delgado,Rosa Inés; Barraza-Villarreal,Albino; Escamilla-Nú?ez,María Consuelo; Solano-González,Maritsa; Moreno-Macías,Hortensia; Romieu,Isabelle;
Salud Pública de México , 2009, DOI: 10.1590/S0036-36342009000300010
Abstract: objective:to evaluate the relation between diet and the development of asthma and allergic rhinitis in schoolchildren from cuernavaca, morelos, mexico. material and methods:we apply the isaac's questionnaire in 5460 schoolchildren from 6 to 8 and 11-14-year-old of elementary level selected in random form. six groups of food were formed using a hierarchic clusters analysis and the association was evaluated using logistic regression models. results:the consumption of fast food had an adverse effect for current wheezing (or=1.82; ci95%=1.16-2.87) and the consumption of tidbits for more than three episodes of wheezing (or=2.26; ci95%=1.04-4.95) and nasal symptoms without cold, or=1.35 (ic95%;1.06-1.71). conclusions:this study provides evidence that the diet plays a very important role since the high consumption of fast food and tidbits increased the risk of asthma and rhinitis symptoms.
Association between the plasma/whole blood lead ratio and history of spontaneous abortion: a nested cross-sectional study
Héctor Lamadrid-Figueroa, Martha M Téllez-Rojo, Mauricio Hernández-Avila, Belem Trejo-Valdivia, Maritsa Solano-González, Adriana Mercado-Garcia, Donald Smith, Howard Hu, Robert O Wright
BMC Pregnancy and Childbirth , 2007, DOI: 10.1186/1471-2393-7-22
Abstract: We studied 207 pregnant Mexico City residents during the 1st trimester of pregnancy, originally recruited for two cohorts between 1997 and 2004. Criteria for inclusion in this study were having had at least one previous pregnancy, and having valid plasma and blood Pb measurements. Pb was measured in whole blood and plasma by inductively coupled plasma mass spectrometry using ultra-clean techniques. History of miscarriage in previous pregnancies was obtained by interview. The incidence rate of spontaneous abortion was defined as the proportion of previous pregnancies that resulted in miscarriage. Data were analyzed by means of Poisson regression models featuring the incidence rate of spontaneous abortion as the outcome and continuous or categorized plasma/blood Pb ratios as predictor variables. All models were adjusted for age and schooling. Additionally, logistic regression models featuring inclusion in the study sample as the outcome were fitted to assess potential selection bias.The mean number of miscarriages was 0.42 (range 0 to 4); mean Pb concentrations were 62.4 and 0.14 μg/L in whole blood and plasma respectively. Mean plasma/blood Pb ratio was 0.22%. We estimated that a 0.1% increment in the plasma/blood Pb ratio lead was associated to a 12% greater incidence of spontaneous abortion (p = 0.02). Women in the upper tertile of the plasma/blood Pb ratio had twice the incidence rate of those in the lower tertile (p = 0.02). Conditional on recruitment cohort, inclusion in the study sample was unrelated to observable characteristics such as number of abortions, number of pregnancies, blood Pb levels, age schooling, weight and height.Women with a large plasma/whole blood Pb ratio may be at higher risk of miscarriage, which could be due to a greater availability of placental barrier-crossing Pb.Several studies have reported a positive association between maternal blood lead concentration and the risk of spontaneous abortion [1-3]. This is of concern since one of the
Dysregulation of Ribosome Biogenesis and Translational Capacity Is Associated with Tumor Progression of Human Breast Cancer Cells
Stéphane Belin, Anne Beghin, Eduardo Solano-Gonzàlez, Laurent Bezin, Stéphanie Brunet-Manquat, Julien Textoris, Anne-Catherine Prats, Hichem C. Mertani, Charles Dumontet, Jean-Jacques Diaz
PLOS ONE , 2009, DOI: 10.1371/journal.pone.0007147
Abstract: Protein synthesis is a fundamental cell process and ribosomes - particularly through the ribosomal RNA that display ribozyme activity - are the main effectors of this process. Ribosome biogenesis is a very complex process involving transcriptional as well as many post-transcriptional steps to produce functional ribosomes. It is now well demonstrated that ribosome production is enhanced in cancer cells and that ribosome biogenesis plays a crucial role in tumor progression. However, at present there is an important lack of data to determine whether the entire process of ribosome biogenesis and ribosome assembly is modified during tumor progression and what could be the potential impact on the dysregulation of translational control that is observed in cancer cells. In breast cancer cells displaying enhanced aggressivity, both in vitro and in vivo, we have analyzed the major steps of ribosome biogenesis and the translational capacity of the resulting ribosome. We show that increased tumorigenicity was associated with modifications of nucleolar morphology and profound quantitative and qualitative alterations in ribosomal biogenesis and function. Specifically cells with enhanced tumor aggressivity displayed increased synthesis of 45S pre-rRNA, with activation of an alternative preRNA synthetic pathway containing a 43S precursor and enhanced post-transcriptional methylation of specifc sites located in the 28S rRNA. While the global translational activity was not modified, IRES-initiated translation, notably that of p53 mRNA, was less efficient and the control of translational fidelity was importantly reduced in cells with increased aggressivity. These results suggest that acquisition of enhanced tumor aggressivity can be associated with profound qualitative alterations in ribosomal control, leading to reduced quality control of translation in cancer cells
High dietary calcium intake decreases bone mobilization during pregnancy in humans
Avenda?o-Badillo,Diana; Hernández-ávila,Mauricio; Hernández-Cadena,Leticia; Rueda-Hernández,Gabriela; Solano-González,Maritsa; Ibarra,Luis G; Hu,Howard; Téllez-Rojo,Martha M.;
Salud Pública de México , 2009, DOI: 10.1590/S0036-36342009000700013
Abstract: calcium metabolism of the mother is modified during pregnancy because of the mineralization of the fetus skeleton. objective: to evaluate the association of calcium intake and bone demineralization during pregnancy. material and methods: at each trimester of pregnancy a validated food frequency intake questionnaire was administered to assess individual daily calcium intake in a cohort of 206 pregnant women, residents of mexico city. samples of urine were collected to measure levels of the cross-linked n-telopeptide of type i collagen (ntx), which is a biomarker of bone resorption. the association between calcium ingestion and bone resorption was analyzed using random effects models; non-linear associations were explored using generalized additive models. results: progressive increases in ntx levels were observed during pregnancy; with mean and standard deviation (sd) values during the first, second and third trimester of 76.50 (sd=38), 101.02 (sd=48.86) and 144.83 (sd=61.33) nmol bce/mmol creatinine, respectively. higher dietary calcium intake was associated with lower bone resorption (β=-0.015; p<0.05). the association between age and ntx showed a non-linear trend with an inflexion point around 33 years: increase in maternal age below that point was associated with a decrease in bone resorption, while in older women the increase in age was associated with an increased resorption. conclusions: our results suggest that calcium ingestion, specifically from dairy products, reduces bone resorption during pregnancy. for each 300mg (a glass of milk) of calcium intake there is an estimated reduction in ntx level of 4.8 nmol bce/mmol of creatinine (p<0.05).
Correlación entre la recirculación medido por BTM (Blood Temperature Monitoring) y la presión venosa dinámica inicial como métodos para la detección de estenosis del acceso vascular protésico
Jorge Enrique Marín González,José Guerrero Carrillo,Adriana Puente García,Ma del Mar Andrés Vázquez
Enfermería Nefrológica , 2012,
Análisis entre la recirculación medida por termodilución (BTM?) y la presión venosa dinámica inicial como métodos para la detección de estenosis del acceso vascular protésico
Marín González,Jorge Enrique; Guerrero Carrillo,José; Andrés Vázquez,María del Mar; Puente García,Adriana;
Enfermería Nefrológica , 2012,
Abstract: introduction: vascular access problems represent the highest cause of morbility and mortality in haemodialysis patients. in turn, stenosis is the main cause of dysfunctions of the prosthetic vascular access, and when this problem is not detected in time, it may lead to thrombosis. there are a number of procedures for the detection of vascular access dysfunction, ranging from physical examination, pressure and flow measurements, and non-invasive and invasive imaging tests. initial dynamic venous pressure is a simple tool for monitoring vascular access. aims: the aim of the study is to correlate initial dynamic venous pressure and recirculation as vascular access monitoring methods in haemodialysis patients. material and methods: a prospective assessment of 21 patients with prostheses was carried out over 1 year. clinical signs and objective measurement parameters were recorded such as recirculation by thermodilution, initial dynamic venous pressure with a blood flow of 200 ml/min, haemostasis time and kt/v by ocm, which were compared with the findings of the imaging tests. measurements were taken monthly, with a total of 244. results: ptfe prostheses represented 16.6% of the vascular accesses in our unit during the period of study. the average age was 63 years, and 57% of the patients studied were women. the mean dialysis time was 225 minutes with a kt/v by ocm of 1.44. of the clinical signs, the one with the highest incidence was the presence of pseudoaneurysms, in 42.8%. the mean recirculation was 10.46±2.68% and initial dynamic venous pressure 94.51±19.58 mmhg. a total of 21 events were recorded: 14 fistulographies + angioplasty, 4 thromboses with surgical repair, 2 fistulographies that did not require angioplasty and one thrombosis that was not recovered. when the recirculation and initial dynamic venous pressure measurements are compared with the appearance of adverse events, a significant relationship was found with initial dynamic venous pressure (p<0.05): the
Determination of presence of Tritrichomonas foetus in uterine lavages from cows with reproductive problems Determina o da presen a de Tritrichomonas foetus em lavados uterinos de vacas com problemas reprodutivos
Lady Carolina González-Carmona,Milena Jineth Sánchez-Ladino,Rubiela Casta?eda-Salazar,Adriana del Pilar Pulido-Villamarín
Revista Brasileira de Parasitologia Veterinária , 2012, DOI: 10.1590/s1984-29612012000300005
Abstract: The aim of this study was to determine the presence of Tritrichomonasfoetus in two dairy herds on the Altiplano Cundiboyacense. Twenty-one low-volume uterine lavages from cows with a history of reproductive problems in two dairy herds located in the municipality of Sibaté (Cundinamarca) and Ventaquemada (Boyacá) were evaluated. In the first herd, 10 cows were sampled and in the second, 11 cows, based on three inclusion criteria. The uterine lavages were obtained through infusion of physiological saline solution into the uterine body. The samples were centrifuged and seeded in Tritrichomonas basal medium for 10-15 days at 37 oC. The protozoa were evaluated on the day of sampling and 10 and 15 days after incubation by means of direct viewing under a dark-field microscope. Positive samples were stained with Wright and Lugol to identify the morphological characteristics. This study showed that T. foetus was present in 61.8% of the animals sampled. The determination that T. foetus was present in 61.8% of the samples analyzed is a significant finding given that in the herds evaluated, this agent had not previously been diagnosed. O objetivo do presente estudo, foi determinar a presen a de Tritrichomonas foetus em dois rebanhos leiteiros no Altiplano Cundiboyacense. De vacas com um histórico de problemas reprodutivos, foram avaliados 21 lavados uterinos de pequeno volume, em dois rebanhos leiteiros localizados nos municípios de Sibaté (Cundinamarca) e Ventaquemada (Boyacá). No primeiro rebanho, 10 vacas foram amostradas e no segundo 11, baseado em três critérios de inclus o. Os lavados uterinos foram obtidos mediante infus o de solu o salina fisiológica no corpo do útero. As amostras foram centrifugadas e semeadas em meio de cultura básico para Tritrichomonas por 10-15 dias a 37 oC. Os protozoários foram avaliados no dia da colheita de amostras e 10 e 15 dias após incuba o por meio de visualiza o direta sob um microscópio de campo escuro. As amostras positivas foram coradas com Wright e Lugol para identificar as características morfológicas. Este estudo mostrou que T. foetus estava presente em 61,8% dos animais amostrados. A determina o de que T. foetus estava presente em 61,8% das amostras analisadas é um achado significativo, dado que nos rebanhos avaliados, esse agente n o tinha sido previamente diagnosticado.
Análisis entre la recirculación medida por termodilución (BTM ) y la presión venosa dinámica inicial como métodos para la detección de estenosis del acceso vascular protésico Analysis of recirculation measured by thermodilution (BTM ) and initial dynamic venous pressure as methods for the detection of stenosis in prosthetic vascular access
Jorge Enrique Marín González,José Guerrero Carrillo,María del Mar Andrés Vázquez,Adriana Puente García
Enfermería Nefrológica , 2012,
Abstract: Introducción: Los problemas de acceso vascular suponen la mayor causa de morbilidad y mortalidad en el paciente en hemodiálisis. La estenosis es a su vez la principal causa de disfunción del acceso vascular protésico, y cuando éste problema no se logra detectar a tiempo, puede derivar en trombosis. Existen múltiples procedimientos para la detección de disfunción del acceso vascular desde la exploración física, mediciones de presión y flujo, así como pruebas de imagen no invasivas e invasivas. La Presión Venosa Dinámica inicial, es una herramienta sencilla de seguimiento del acceso vascular. Objetivos: El objetivo del estudio es correlacionar la presión venosa dinámica inicial y la recirculación como métodos de vigilancia del acceso vascular en pacientes en hemodiálisis. Material y métodos: Se evaluaron de forma prospectiva 21 pacientes con prótesis durante 1 a o. Se registraron signos clínicos y parámetros de medición objetivos como recirculación por termodilución, presión venosa dinámica inicial con flujo de sangre de 200 ml/min, tiempo de hemostasia, y KT/V por OCM, contrastándose con los hallazgos de las pruebas de imagen. Se realizaron mediciones mensualmente, con un total de 244. Resultados: La prótesis de PTFE representó el 16,6% de los accesos vasculares en nuestra unidad durante el periodo de estudio. La media de edad fue de 63 a os con un 57% de mujeres. El tiempo medio de diálisis fue de 225 min con un Kt/V por OCM de 1,44. De los signos clínicos, la mayor incidencia fue presencia de pseudoaneurismas, en un 42,8%. La media de recirculación fue 10,46±2,68% y la presión venosa dinámica inicial 94,51±19,58 mmHg. Se registraron en total 21 eventos: 14 fistulografías+ angioplastia, 4 trombosis con reparación quirúrgica, 2 fistulografías sin necesidad de angioplastia y una trombosis no recuperada. Cuando se compararon las mediciones de recirculación y presión venosa dinámica inicial, con la aparición de eventos, se encontró relación significativa con la presión venosa dinámica inicial (p<0.05), a medida que es más elevada, mayor probabilidad de eventos. No encontramos correlación entre presión venosa dinámica inicial y recirculación. Conclusiones: A la vista de estos resultados podemos concluir que la presión venosa dinámica inicial es un parámetro útil y de fácil medición que se relaciona con la aparición de eventos adversos en las prótesis de PTFE. Sin embargo no encontramos relación entre la presión venosa dinámica inicial y la recirculación del acceso vascular. Introduction: Vascular access problems represent the highest cause of morbility and mo
Variability in the Light Absorption Coefficient by Phytoplankton, Non-Algal Particles and Colored Dissolved Organic Matter in the Northern Gulf of California  [PDF]
Stella P. Betancur-Turizo, Adriana G. González-Silvera, Eduardo Santamaría-Del-ángel, Roberto Millán-Nú?ez, Eduardo Millán-Nú?ez, Héctor García-Nava, Víctor M. Godínez, Laura Sánchez-Velasco
Open Journal of Marine Science (OJMS) , 2017, DOI: 10.4236/ojms.2018.81002
Variability of the optical properties of the northern Gulf of California (México) were analyzed for the first time based on six cruises performed from spring to summer (March to September) between 2008 and 2013. The changes observed in the absorption by three seawater components (phytoplankton, detritus and chromophoric dissolved organic matter or CDOM) were analyzed in relation to changes in bio-optical regions and composition of the phytoplankton community (determined based on phytoplankton pigments). Two regions with unique bio-optical characteristics were identified separated by a narrow transition zone: the Upper Gulf of California (UGC) and Northern Gulf of California (NGC). Despite the temporal changes in their spatial distribution they maintained particular characteristic. UGC is characterized by an average Chla of 1.78 mg/m3, the dominance of microphytoplankton (diatoms and dinoflagellates) and a stronger contribution of detritus to total light absorption. NGC is characterized by an average Chla of 0.7 mg/m3 and the predominance of picophytoplankton, characterized by the dominance of zeaxanthin (marker pigment for cyanobacteria) and/or chlorophyll b (marker pigment for green algae), along with a co-dominium by CDOM and phytoplankton to light absorption. Results indicate that Case II waters can be very different when evaluating the individual contribution by phytoplankton, detritus and CDOM to total light absorption what has to be considered for the selection of bio-optical models for each specific region what can also help to a better definition of the related uncertainties.
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