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Potencial medicinal del género Sapindus L. (Sapindaceae) y de la especie Sapindus saponaria L.
Abreu Guirado,Orlando A;
Revista Cubana de Plantas Medicinales , 2005,
Abstract: the etnomedical information and the tested biological activities of the genus sapindus (sapindaceae) and of the species that grows in cuba, s. saponaria l. , published in the available literature and included in the napralert, native american ethnobotany and phytochemical & ethnobotanical database, are exposed. 55 traditional uses and 29 different biological effects of the genus have been reported, whereas of s. saponaria , commonly known as “jaboncillo”, 32 and 14 have been found, respectively. this species is acknowledged the greatest amount of traditional applications and as s. trifoliatu , it presents the higest number of biological tests. several of the uses referred in cuba for the species of the genus sapindus coincide with those in other latitudes. it is stressed the use of different parts of the trees or bushes of these species in other cultures, mainly for health problems in the gynecoobstetric field, such as an abortive, delivery inducer and in the treatment of uterine pain. it is also used as an emetic, in the treatment of hysteria., antifebrile, piscicide and molluscacide , among others. in one way or another, various traditional uses have been confirmed by laboratory tests, which demonstrate the validity of the traditional knowledge of the peoples as a criterion for studying the medicinal plants.
Potencial medicinal del género Sapindus L. (Sapindaceae) y de la especie Sapindus saponaria L. Medicinal potential of the genus Sapindus L. (Sapindaceae) and of the Sapindus saponaria L. species
Orlando A Abreu Guirado
Revista Cubana de Plantas Medicinales , 2005,
Abstract: Se expone la información etnomédica y actividades biológicas comprobadas del género Sapindus (Sapindaceae) y de la especie que crece en Cuba, Sapindus saponaria L., publicada en la literatura disponible e incluida en las bases de datos: NAPRALERT, Native American Ethnobotany y Phytochemical & Ethnobotanical Database. Del género se han informado 55 usos tradicionales y 29 efectos biológicos diferentes, mientras que de S. saponaria, conocida comúnmente como “jaboncillo”, se encontraron 32 y 14, respectivamente. A esta especie es a la que se le reconoce un mayor número de aplicaciones tradicionales y al igual que S. trifoliatu, presenta el mayor número de ensayos biológicos realizados. Varios de los usos referidos en Cuba para las especies del género Sapindus coinciden con los de otras latitudes. Se destaca el empleo de diferentes partes de los árboles o arbustos de estas especies en otras culturas, fundamentalmente en problemas de salud que competen a la Ginecobstetricia, como son: su uso como abortivo, inductor del parto y en el tratamiento del dolor uterino; también se ha informado su utilidad como emético, en el tratamiento de la histeria, como antifebrífugo, piscida y molusquicida, entre otros. De una forma u otra, varios empleos tradicionales se han corroborado mediante ensayos de laboratorio; lo que demuestra la validez del conocimiento tradicional de los pueblos como criterio para el estudio de las plantas medicinales. The etnomedical information and the tested biological activities of the genus Sapindus (Sapindaceae) and of the species that grows in Cuba, S. saponaria L. , published in the available literature and included in the NAPRALERT, Native American Ethnobotany and Phytochemical & Ethnobotanical Database, are exposed. 55 traditional uses and 29 different biological effects of the genus have been reported, whereas of S. saponaria , commonly known as “jaboncillo”, 32 and 14 have been found, respectively. This species is acknowledged the greatest amount of traditional applications and as S. trifoliatu , it presents the higest number of biological tests. Several of the uses referred in Cuba for the species of the genus Sapindus coincide with those in other latitudes. It is stressed the use of different parts of the trees or bushes of these species in other cultures, mainly for health problems in the gynecoobstetric field, such as an abortive, delivery inducer and in the treatment of uterine pain. It is also used as an emetic, in the treatment of hysteria., antifebrile, piscicide and molluscacide , among others. In one way or another, various tr
Estrategias en la selección de las plantas medicinales a investigar
Abreu Guirado,Orlando A.; Cuéllar Cuéllar,Armando;
Revista Cubana de Plantas Medicinales , 2008,
Abstract: background: plant species are estimated to be 250 000 to 500 000, so the selection criteria for development of drugs may sometimes be a problem. if they are not properly designed, then the results may be useless. objectives: to analyze several strategies for selection that can be adopted. methods: seven criteria were included and assessed for the research approach. results: the most used current criteria were random collection (mainly influenced by commercial interests) and ethnomedical knowledge of peoples-based criteria (mainly academic performance considered); other recent disciplines like genomics and metabolomics are already been implemented in this field. when appropriate, these criteria may be combined. furthermore, some elements that seem to have no relation with selection criteria may be essential in this regard such as information technologies, specialized database and conservation and bioethical aspects. conclusions: the selection criteria of plant species to develop drugs may be varied, restrictions are not always kept and the combination of some of them is feasible.
Estrategias en la selección de las plantas medicinales a investigar Strategies for the selection of medicinal plants to be studied
Orlando A. Abreu Guirado,Armando Cuéllar Cuéllar
Revista Cubana de Plantas Medicinales , 2008,
Abstract: Antecedentes: las especies vegetales se calculan entre 250 000 y 500 000, el criterio en su selección para desarrollar medicamentos en ocasiones puede ser un problema; de no concebirse adecuadamente, los resultados pueden ser infructuosos. Objetivo: analizar diferentes estrategias que se pueden adoptar en este sentido. Métodos: se incluyen y valoran 7 criterios para el enfoque de estas investigaciones. Resultados: los criterios más empleados hoy día son: colecta al azar (sobre todo cuando hay intereses comerciales) y basados en el conocimiento etnomédico de los pueblos (máxime en el desempe o académico); otras disciplinas más recientes como la genómica y metabolómica tienen ya su aplicación en este campo. En la práctica, cuando procede, estos criterios se pueden combinar. Además, pueden ser esenciales en la selección elementos que en apariencia no se relacionan, como son las tecnologías de la información, bases de datos especializadas, aspectos conservacionistas y bioéticos. Conclusiones: los criterios para seleccionar especies del reino vegetal para desarrollar medicamentos pueden ser variados, los límites entre estos no siempre se mantienen y la combinación entre algunos es factible. Background: Plant species are estimated to be 250 000 to 500 000, so the selection criteria for development of drugs may sometimes be a problem. If they are not properly designed, then the results may be useless. Objectives: to analyze several strategies for selection that can be adopted. Methods: Seven criteria were included and assessed for the research approach. Results: The most used current criteria were random collection (mainly influenced by commercial interests) and ethnomedical knowledge of peoples-based criteria (mainly academic performance considered); other recent disciplines like Genomics and Metabolomics are already been implemented in this field. When appropriate, these criteria may be combined. Furthermore, some elements that seem to have no relation with selection criteria may be essential in this regard such as information technologies, specialized database and conservation and bioethical aspects. Conclusions: the selection criteria of plant species to develop drugs may be varied, restrictions are not always kept and the combination of some of them is feasible.
Bioseguridad:: su comportamiento
Abreu Guirado,Odalis; Rodríguez Heredia,Odalys; Pérez Delgado,Ernesto; González García,Magda;
Revista Archivo M??dico de Camag??ey , 2008,
Abstract: background: the biological security has been burning theme in the public opinion of many countries in the last 60 years. objective: to analyze the behavior of biological security in the educational provincial hospitals ?manuel ascunce domenech? and ?eduardo agramonte pi?a?, of camagüey province. method: a descriptive study from january to december 2006 was performed. the universe of study was constituted by the two hospitals previously mentioned, selected by the simple random method. it was proceed to the application of a questionnaire created according to experts criterion, in the services or departments with biological risk, which constituted the fundamental registry of the investigation. besides, a survey to measure the level of knowledge on biosecurity to the 33,3% of workers with biological risk was applied. results: in both hospitals workers exposed to biological risk represented the 57%, with predominance of nurses, doctors and auxiliaries; bad evaluation in the indicators of the program of hospital biosecurity was obtained. greater numbers of incidents in the provincial pediatric hospital were recorded, a subregistry in both centers existed, exposures and damages prevailed, especially in the microbiology laboratory, the most frequent causes were spills of blood and other liquids, breaks of pipes and flasks and pricks, fundamentally in the technical personnel. conclusions: no professional diseases by biological agents were reported.
Fitoquímica del género Vaccinium (Ericaceae)
Abreu Guirado,Orlando A.; Cuéllar Cuéllar,Armando; Prieto,Sylvia;
Revista Cubana de Plantas Medicinales , 2008,
Abstract: background: phytochemistry of genus vaccinium (ericaceae) was reviewed. methods: napralert and phytochemical and ethnobotanical database as well as available literature were accessed. results: a great number of research studies and compounds of 32 species and 23 cultivars were found. predominant metabolites -mainly in the fruit- were benzenoids, flavonoids (cyanidines, hyperoside, epi-cathequine and proanthocyanidines) and phenylpropanoids. geographic distribution of research studies showed that a high number of indigenous latin-american species has not yet been studied as part of a research work. conclusions: the potential of biologically active compounds of this genus represents a likely successful field to develop herbal medicines or nutritional supplements.
Farmacognosia, farmacobotánica, farmacogeografía y farmacoetimología del platanillo de Cuba (Piper aduncum subespecie ossanum)
Abreu Guirado,Orlando A; Rodríguez Tamargo,Ana A; Morgado Montes,Maybel; Cao Vocero,Laura B;
Revista Cubana de Plantas Medicinales , 2012,
Abstract: introduction: pharmacognostic studies are essential on medicinal plant research, as well as in herbal medicine and phytomedicine production. piper aduncum l. (piperaceae) specie known as "platanillo de cuba", has wide recognition due to its traditional use in cuba and other regions. objective: to research the drug derived from piper aduncum (platanillo de cuba) from the pharmacognostic viewpoint in terms of pharmacobotany, pharmacogeography and pharmacoetymology. methods: the pharmacobotanical, geographical distribution and etymological study of this drug was conducted by using specialized literature and determination of macromorphologic characteristics of leaves collected in ciego de ávila province, cuba. results: there are two geographically located infraspecific taxa of the plant commonly called "platanillo de cuba", "guayuyo" o "canilla de muerto" in cuba. one of them -piper aduncum subspecie ossanum (c.dc.) saralegui- is endemic and the topic of this research. macromorphologic characteristics of the drug are comparable to those described in literature. geographical distribution and etymologic aspects of interest were found. conclusions: in the pharmacognostic research, pharmacobotanical, pharmacogeographical and pharmacoetymological studies could be very signicant, as in the case of this plant. for any further research on this species, it is fundamental to approach its taxonomic treatment in the country, since it includes two infraspecific taxa in which geographical location is essential.
Fitoquímica del género Vaccinium (Ericaceae) Phytochemisty of genus Vaccinium (Ericaceae)
Orlando A. Abreu Guirado,Armando Cuéllar Cuéllar,Sylvia Prieto
Revista Cubana de Plantas Medicinales , 2008,
Abstract: Antecedentes: se revisó la fitoquímica del género Vaccinium (Ericaceae) Métodos: se consultaron las bases de datos: NAPRALERT y Phytochemical and Ethnobotanical Database y la literatura disponible. Resultados: se halló un elevado número de estudios y compuestos de 32 especies y 23 cultivares de algunas de ellas. Los metabolitos predominantes, principalmente en el fruto, fueron: benzenoides, flavonoides (cianidinas, hiperósido, epi-catequina y proantocianidinas) y fenilpropanoides. La distribución geográfica de los estudios indica que el elevado número de especies autóctonas de Latinoamérica, prácticamente no se ha investigado. Conclusiones: la potencialidad de compuestos biológicamente activos en este género representa un campo con probabilidades de éxito para la obtención de medicamentos herbarios o suplementos nutricionales. Background: Phytochemistry of genus Vaccinium (Ericaceae) was reviewed. Methods: NAPRALERT and Phytochemical and Ethnobotanical Database as well as available literature were accessed. Results: A great number of research studies and compounds of 32 species and 23 cultivars were found. Predominant metabolites -mainly in the fruit- were benzenoids, flavonoids (cyanidines, hyperoside, epi-cathequine and proanthocyanidines) and phenylpropanoids. Geographic distribution of research studies showed that a high number of indigenous Latin-American species has not yet been studied as part of a research work. Conclusions: The potential of biologically active compounds of this genus represents a likely successful field to develop herbal medicines or nutritional supplements.
Farmacognosia, farmacobotánica, farmacogeografía y farmacoetimología del platanillo de Cuba (Piper aduncum subespecie ossanum) Pharmacognosy, pharmacobotany, pharmacogeography, and pharmacoetimology of platanillo de Cuba (Piper aduncum subspecie ossanum)
Orlando A Abreu Guirado,Ana A Rodríguez Tamargo,Maybel Morgado Montes,Laura B Cao Vocero
Revista Cubana de Plantas Medicinales , 2012,
Abstract: Introducción: los estudios farmacognósticos son de vital importancia en la investigación de plantas medicinales, así como en la producción de medicamentos herbarios y fitofármacos. La especie Piper aduncum L. (Piperaceae), posee un gran aval de uso tradicional en Cuba y otras regiones del mundo. Objetivo: estudiar desde el punto de vista farmacognóstico la droga de Piper aduncum en cuanto a botánica, geografía y etimología. Métodos: se realizó el estudio botánico, de distribución geográfica y etimología de esta droga, mediante el empleo de literatura especializada y la determinación de caracteres macromorfológicos de hojas de esta planta colectada en la provincia Ciego de ávila, Cuba. Resultados: existen 2 categorías infraespecíficas bien localizadas geográficamente de la planta que en Cuba se llama por lo común platanillo de Cuba, guayuyo o canilla de muerto, una de las cuales -Piper aduncum subespecie ossanum (C.DC.) Saralegui-, endémica, es la que se investiga. Las características macromorfológicas de la droga coinciden con las descritas en la literatura. Se hallaron aspectos etimológicos y de distribución geográfica de interés relacionados con esta planta. Conclusiones: en las investigaciones farmacognósticas los estudios botánicos, geográficos y etimológicos pueden ser de gran significación, como en el caso de esta planta. Para cualquier investigación con esta especie resulta imprescindible abordar su tratamiento taxonómico en el país, porque incluye 2 categorías infraespecíficas en las cuales la ubicación geográfica es fundamental. Introduction: pharmacognostic studies are essential on medicinal plant research, as well as in herbal medicine and phytomedicine production. Piper aduncum L. (Piperaceae) specie known as "platanillo de Cuba", has wide recognition due to its traditional use in Cuba and other regions. Objective: to research the drug derived from Piper aduncum (platanillo de Cuba) from the pharmacognostic viewpoint in terms of pharmacobotany, pharmacogeography and pharmacoetymology. Methods: the pharmacobotanical, geographical distribution and etymological study of this drug was conducted by using specialized literature and determination of macromorphologic characteristics of leaves collected in Ciego de ávila province, Cuba. Results: there are two geographically located infraspecific taxa of the plant commonly called "platanillo de Cuba", "guayuyo" o "canilla de muerto" in Cuba. One of them -Piper aduncum subspecie ossanum (C.DC.) Saralegui- is endemic and the topic of this research. Macromorphologic characteristics of the drug are compar
Actividad molusquicida del Paraiso (Melia azedarach L.) (Meliaceae) sobre Lymnaea cubensis, molusco vector de Fasciolosis
Perez Marlene Pi?a,Fernandez Lorenzo Diéguez,Guirado Orlando A. Abreu,Capote Raiza Vázquez
Revista de Saúde Pública , 1998,
Abstract: INTRODUCCIóN: La Fasciolosis constituye en diversas regiones una fuente importante de pérdidas económicas y cuando se descuidan las medidas de control de sus hospedadores (moluscos), junto a condiciones ecológicas favorables, pueden ocurrir casos aislados de Fasciolosis humana. Dentro de los métodos alternativos para su control está el uso de extractos vegetales y se pretendió evaluar el probable empleo del jugo extraído del fruto y semillas del Paraiso (Melia azedarach L.) en el control de Lymnaea cubensis, principal vector de la Fasciolosis en Cuba. MATERIAL Y MéTODO: Diferentes concentraciones del jugo extraído del fruto y semillas del Paraiso (Melia azedarach L.) fueron testados para determinar las dosis letales media (DL50) y máxima (DL90) usando un programa computarizado Probit-Log. Siete series experimentales fueron probadas usando 72 moluscos en cada una. Para determinar la influencia sobre la frecuencia cardíaca fueron testados tres grupos de 10 moluscos, dos fueron tratados con las DL50=0,88627 y DL90=1,7641, respectivamente, mientras que el tercero fue considerado como testigo. RESULTADOS Y CONCLUSIONES: Se observó una marcada influencia de ambas dosis sobre la frecuencia cardíaca del molusco estudiado. Estos resultados son alentadores, pues demuestran el potencial empleo de esta planta en el control de moluscos indeseables.
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