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Search Results: 1 - 10 of 2978 matches for " Abdoulaye Ba "
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Pyramidal and Granule Cells Distribution through Hippocampal Fields: An Index for Sensory Information Processing  [PDF]
Abdoulaye Ba
Journal of Behavioral and Brain Science (JBBS) , 2015, DOI: 10.4236/jbbs.2015.55018
Abstract: Background: This work aims at investigating the histology of hippocampus formation as structural model of information processing. The study addressed the question whether the pattern of cellular type distribution within hippocampal fields could be used as support of information processing in the hippocampus. Method: Pyramidal-shaped neurons presenting both cytoplasm and nucleus outlined clearly were measured systematically on brain slides, using a light microscope connected to a microcomputer equipped with a scanner software for measuring particles. Morphological types of cells were identified following class sizes and their distribution determined through hippocampal fields. Results: A battery of statistical tests: Sturges’ classification, class sizes distribution around overall mean, Bartlett’s sphericity test, principal components analysis (PCA) followed by correlations matrix analysis and ANOVA allowed two cellular groups to be identified in the hippocampus: large and small pyramidal-shaped cells. Conclusion: The results show that sensory information processing in the hippocampus could be built on two classes of pyramidal neurons that differed anatomically with probably different physiological functions. The study suggests combination ensembles clustering large and small pyramidal cells at different rates, as fundamental signaling units of the hippocampus.
Effect of Compaction Moisture Content on the Resilient Modulus of Unbound Aggregates from Senegal (West Africa)  [PDF]
Makhaly Ba, Meissa Fall, Oustasse Abdoulaye Sall, Fatou Samb
Geomaterials (GM) , 2012, DOI: 10.4236/gm.2012.21003
Abstract: This paper presents the results of research conducted to investigate the effect of compaction moisture content on Resil- ient Modulus (Mr) of unbound aggregates. Three different aggregates (GRB, Basalt and Bandia limestone) was collect- ed from different sites within Senegal and then subjected to repeated load triaxial tests. Test results showed that the ef- fect of compaction water content is more significant in the dry side than in the wet side. The compaction water content has less effect on the GRB and the Basalt than on the Bandia limestone. GRB and Basalt are cohesionless materials and allow water to drain even during the compaction procedure. Change in water content increases as the compaction water content increases because of the drainage of the excess water during the compaction and loading procedures. For GRB and Basalt, at Wopt + 1.5%, most of the excess water is drained during the compaction of the sample and continue to be drained during the Resilient Modulus test. For the Bandia limestone, this drainage is less significant due to cohesion, absorption and hydratation.
Influence of the Elastic Modulus of the Soil and Concrete Foundation on the Displacements of a Mat Foundation  [PDF]
Oustasse Abdoulaye Sall, Meissa Fall, Yves Berthaud, Makhaly Ba
Open Journal of Civil Engineering (OJCE) , 2013, DOI: 10.4236/ojce.2013.34027
Abstract:

In this paper, we suggest to study the behavior of a mat foundation on subsoil from the plate theory taking into account the soil-structure interaction. The objective is to highlight the soil-structure interaction particularly the influence of the rigidities of the soil and the concrete on the subgrade reaction (k) and the displacements of the mat foundation subjected to vertical loads. From plate theory and the soil-structure interaction, the general equation is reached. This equation depends more on the subgrade properties than the concrete foundation properties. Consequently, the behavior of the mat foundation is more influenced by soil properties than the concrete.

High Field MRI in Human African Trypanosomiasis (HAT)  [PDF]
Cherif Mohamadou Aidara, Caroline Magne, Philomene Kouna, Gaelle Ebinda Mipinda, Abdoulaye Dione Diop, Abdoulaye Ndoye Diop, Sokhna Ba
Open Journal of Radiology (OJRad) , 2017, DOI: 10.4236/ojrad.2017.73021
Abstract: Human African Trypanosomiasis (HAT) or sleeping thickness is a forest and rural disease; where agriculture is the main activity. It is a chronic and lethal disease without treatment. HAT is caused by two parasites; Trypanosoma Brucei Gambiense (gTB) and Trypanosoma Brucei Rhodesiense (rTB) transmitted to humans by the tsetse fly. It is endemic condition in Africa between the 15° north latitude and the 20° south latitude. It is reported outside this area in travelers who stayed in endemic zone. Infection by gTB is wider and more frequent (98%) than that by rTB (2%). The Democratic Republic of Congo is the most affected country with more than 75% of reported cases. The geographical distribution is not homogeneous. There are more affected regions in a zone called “foci” which represents areas favorable to the development of the vector. Its diagnosis and treatment are very important because of its social and economic impact at both the individual and community levels. Promising molecules including fexinidazole are currently undergoing testing. Nowadays populations move more and more easily but the discovery of this disease in daily neuroradiological practice is exceptional. We propose in this paper through two observations, reminders on epidemiological, clinical and MRI features of HAT. It typically performs the edematous, bilateral and diffuse encephalitis. It is important to distinguish these aspects from the arsenic-induced encephalitis that may occur during treatment. Only vector control allows eradicating this disease. WHO has set targets elimination of HAT as a public health problem for 2020 deadline.
Morphometry of the Portal Vein: Ultrasound Anatomy about 1000 Cases  [PDF]
Abdoulaye Kanté, Abdoulaye Koné, Daouda Camara, Bréhima Bengaly, Bréhima Coulibaly, Drissa Traoré, Babou Ba, Mariam Daou, Nouhoum Ongo?ba
Forensic Medicine and Anatomy Research (FMAR) , 2019, DOI: 10.4236/fmar.2019.72007
Abstract: Aim: The aim of this study is to determine from a series of 1000 cases the usual dimensions of the portal vein according to the medical ultrasound. Methodology: We realized a transverse study over 2 years (from January 2015 to December 2017). It concerned an ultrasound exploration of the portal vein. The studied population was healthy voluntary subjects visible without history of abdominal trauma and abdominal operating scar. Results: The average age was 39 years ± 12.16 with extremes of 19 years and 70 years. The decade of 21 - 29 years represented 46.2%. The transverse diameter of the portal vein in its origin varied between 8 and 10 mm in 57.9% of the cases. The average was 9.05 ± 2.82 mm with extremes of 5 and 16 mm. The transverse diameter of the portal vein in its ending varied between 8 and 10 mm in 56.9%. In 29.8% of the cases, the length of the portal vein was between 61 and 70 mm and in 8.8% between 81 and 100 mm. The average length was 58 ± 22.3 mm. Before its penetration in the liver, the portal vein divided into 2 branches in 967 cases (96.7%) and in 3 branches in 33 cases (3.3%). Conclusion: This original study shows the normal dimensions of the portal vein to Malian.
Anatomy of the Gall-Bladder in the Ultrasound about 1000 Cases  [PDF]
Bréhima Coulibaly, Abdoulaye Kanté, Abdoulaye Koné, Bréhima Bengaly, Babou Ba, Youlouza Coulibaly, Oncoumba Diarra, Adama Seriba Diarra, Drissa Traoré, Mariam Daou, Nouhoum Ongo?ba
Forensic Medicine and Anatomy Research (FMAR) , 2019, DOI: 10.4236/fmar.2019.72008
Abstract: Aim: The aim of this work is to determine the dimensions and the capacity of the gall-bladder by ultrasound. Methodology: We realized a descriptive study over 2 years (from January, 2015 till December, 2017). It concerned an ultrasound exploration of the gall-bladder. The studied population was healthy voluntary subjects visible and on an empty stomach for 12 hours, without history of abdominal trauma and abdominal operating scar. The carrying subjects of the tracks of abdominal trauma or of abdominal operating scar were not included. Results: The average age was of 39 years ± 12.16 with extreme of 10 years and 89 years. It was 500 women (50%) and of 500 men (50%) with a sex ratio of 1. To 450 subjects (45%) the width of the gall-bladder of the subjects varied between 21 and 30. The average was 22.63 mm ± 7.9. Extremes were from 9 to 55 mm. The measurements made by the three sonographers showed no significant difference. The sensitivity of ultrasound in the visualization of the gallbladder was 100%. The length of the gall-bladder was between 61 and 70 mm. The average was 65.35 ± 14.48. Extremes were 26 and 142 mm. Conclusion: This original study shows the normal dimensions of the gall-bladder to Malian.
Influence of the Soil-Structure Interaction in the Behavior of Mat Foundation  [PDF]
Oustasse Abdoulaye Sall, Meissa Fall, Yves Berthaud, Makhaly Ba, Mapathé Ndiaye
Open Journal of Civil Engineering (OJCE) , 2014, DOI: 10.4236/ojce.2014.41007
Abstract:

This article focuses on the study of the behavior of a soil mass under a plate subjected to a uniformly distributed load. The aim of this paper is to highlight the soil-structure interaction with a linear variation of the mechanical properties of the soil with the depth. The theory of plates and the soil-structure interaction has allowed reaching the general equation of the problem which depends on both the mechanical properties of the concrete and the subgrade. This study shows that the linearity of the elastic modulus of subgrade leads to larger displacements when this modulus is assumed to be constant in the soil mass. It also shows that the Poisson’s ratio of soil and mechanical properties of the concrete have an insignificant influence on the displacements. This analysis also shows that the points in the upper half-thickness of soil are the most sensitive to the parameters of the model.

Influence of Mechanical Properties of Concrete and Soil on Solicitations of Mat Foundation  [PDF]
Oustasse Abdoulaye Sall, Makhaly Ba1, Mapathé Ndiaye, Daouda Sangare, Mathioro Fall, Alassane Thiam
Open Journal of Civil Engineering (OJCE) , 2015, DOI: 10.4236/ojce.2015.52025
Abstract: This work studies the influence of mechanical and geometrical characteristics of the concrete and the soil on the stresses in a mat foundation. In this study, the soil-structure interaction is modeled by two parameters, the modulus of subgrade vertical reaction (k) and the modulus of subgrade horizontal reaction (2T). These two parameters are dependent on the geometrical and mechanical characteristics of the system. Results of this study show a sensitivity of solicitations to variations of geometrical and mechanical characteristics of the model. Although solicitations in the plate are sensitive to mechanical properties of concrete, these solicitations are strongly influenced by the mechanical and geometrical characteristics of the soil mass. However, it should be noted that the influence of Eb is denoted in the center of the plate whereas the Es feels almost in the same manner over the entire extent of the plate. This study also shows that for the same load cases, the values of the torsion moment and shear stress are not significant those of bending moments and normal stresses, respectively.
Effects of Ovariectomy and 17β-Estradiol Replacement on Dopamine D2 Receptors in Female Rats: Consequences on Sucrose, Alcohol, Water Intakes and Body Weight  [PDF]
Abdoulaye Ba, Seydou Silué, Brahima Bamba, Lociné Bamba, Serge-Vastien Gahié
Journal of Behavioral and Brain Science (JBBS) , 2018, DOI: 10.4236/jbbs.2018.81001
Abstract: Background: Mechanisms underlying overeating-induced obesity in post-menopausal woman include functional lack of 17β-estradiol dysregulating dopamine D2 receptors, thereby inducing food addiction, glucose craving or alcohol dependence through reward circuitry. This study aimed at further understanding 17β-estradiol and dopamine D2 receptors interferences in the etiology of woman obesity. Method: Seventy-two Wistar female rats weighing 200 - 205 g, individually-housed, were divided into non-ovariectomized control (C = 6 groups) and ovariectomized rats (OVX = 6 groups) which were concurrently subjected to the following treatments: Non-drug-treated (DMSO vehicle), 17β-estradiol (E2, 5 μg/kg, s.c.), sulpiride (SUL, 20 mg/kg, i.p.), bromocriptine (BR, 0.1 mg/kg, i.p.), E2 + SUL or E2 + BR, designating the 6 constitutive groups of either control or ovariectomy. Within each experimental group, consumption of different solutions (10% alcohol, 10% sucrose and water) as well as food intake and body weight were daily measured, for 10 consecutive days. Results: This study indicated that D2S was a specific inducer of alcohol and food intakes, but reduced sugar consumption. In addition, 17β- estradiol regulated the body weight set point, modulating D2S functions towards increased food intake at lower weights and decreased food intake at higher weights. D2S met the slow genomic actions induced by 17β-estradiol. Conversely, D2L inhibited alcohol and food intakes, but induced specifically sugar consumption, thereby regulating blood glucose levels and promoting energy expenditure in reducing body weight. Indeed, 17β-estradiol exerted a tonic inhibition on D2L which was released by OVX, exacerbating sugar intake and increasing body weight. D2L mediated the rapid metabolic effects of 17β-estradiol. Conclusion: Our results supported physiological data reporting that activation of the mostly expressed presynaptically D2S-class autoreceptors decreased dopamine release stimulating food intake, whereas activation of the predominantly postsynaptic isoform D2L receptors increased dopamine activity inhibiting food intake. Our studies indicated that 17β-estradiol acted on the two types of D2 receptors showing opposite functions to equilibrate energy intake vs. expenditure for weight set point regulation. Our data also supported biochemical findings reporting that 17β-estradiol induced D2 genes transcriptional regulation, thereby involving both types of D2 receptors
Molecular Analysis of Clerodendrum formicarum Effects in Painful Diabetic Neuropathy in Rat  [PDF]
Ghislain Loubano-Voumbi, Mor Diaw, Valentin Ouedraogo, Abdou Khadir Sow, A?ssatou Seck, Luc Magloire Anicet Boumba, Abdoulaye Ba, Abdoulaye Samb
World Journal of Neuroscience (WJNS) , 2015, DOI: 10.4236/wjns.2015.54023
Abstract: The pathophysiology of diabetic neuropathic pain is due to primarily metabolic and vascular factors. There is an increase in sorbitol and fructose, glycated end products, reactive oxygen species and activation of protein kinase C in the diabetic state. All these factors lead to direct damage to the nerves. Taking effective clinical management of neuropathic pain is based on a pharmacological treatment that has shown their limits and many side effects. The hypothesis of central sensitization inhibited by Clerodendrum formicarum, an African pharmacopoeia plant used to treat headaches, arthritis, epilepsy and chronic pain could act on astrocytes and microglial cells. The objective of this work is to study the effect of Clerodendrum formicarum (100, 150 and 200 mg/kg body weight) on astrocytes and microglial cells in a model of diabetic neuropathic pain induced by alloxan monohydrate (150 mg/kg). We noted a suppression of mechanical allodynia and mechanical hyperalgesia respectively by the Von Frey filaments test and the pressure test on the paw by the Clerodendrum formicarumextracts (ECF) at different doses from 2 h at the first injection of the ECF. After 5 days of treatment, we expressed by Western Blot bands of different proteins and by quantitative RT-PCR, we determined inhibition of the expression of GFAP, CD11b and isoforms 1 and 2 of cyclooxygenase. These results suggest that ECF inhibits the activation of astrocytes, microglial cells and cyclooxygenase signaling pathway.
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