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Search Results: 1 - 10 of 38 matches for " Abdolrasoul Mehrsai "
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A Comparison between Clinical and Pathologic Staging in Patients with Bladder Cancer
Abdolrasoul Mehrsai,Daryosh Mansoori,Mohamad Taheri Mahmodi,Alireza Sina
Urology Journal , 2004,
Abstract: Purpose: To determine the accuracy of clinical staging methods of bladder cancer and TURBT results in estimating the pathologic stage of tumor. Materials and Methods: Thirty two patients who had undergone radical cystectomy were studied in this retrospective survey. The results of bimanual examination, cystoscopy, TURBT pathology report and the tumor contour in CT scan, (size, infiltrative deepness, pelvic lymph nodes involvement and hydronephrosis) were recorded. The type of surgery and pathologic report of cystectomy sample were analyzed as well. Then the results of bimanual examination, tumor size, hydronephrosis and CT scan findings including tumor infiltrative deepness, pelvic lymph adenopathy and TURBT findings were compared to pathologic results of cystectomy sample. Results: Seven patients were females and 25 were males. Their mean age was 62 (range 36 to 80) years. Gross hematuria and irritative urinary symptoms were the most common complaints. The duration between symptom manifestation and patient’s referral was 5 days to 72 months (mean 12 months). Bimanual examination in estimating the extravesical involvement of tumor had a specificity of 82%, sensitivity of 46%, positive predictive value of 70% and negative predictive value of 63%. The size of tumor in determining extravesical involvement had a specificity of 41%, sensitivity of 93%, and positive predictive value of 58% and negative predictive value of 87%. Hydronephrosis was present in 15 patients of whom, 14 (93%) had bladder muscle involvement. CT scan specificity was 70%, and sensitivity was 46% regarding pelvic lymph adenopathy and perivesical fat involvement. In TURBT report no muscle sample was observed in 11 cases, so that the interpretations of results were impossible. The reported grade of tumor was lower than pathologic sample of cystectomy in 4 patients. Conclusion: Clinical staging in invasive bladder cancers has not high accuracy regarding the involvement of bladder surrounding fats and pelvic adenopathies. A tumor sized more than 5 cm could be sensitive in estimating extravesical involvement. Positive predictive value of hydronephrosis is considerable regarding bladder muscle involvement. Tumor understaging by TURBT is happened in high percentage of patients with invasive bladder cancer.
Detection of Recurrent Bladder Cancer NMP22 Test or Urine Cytology?
Jalil Hosseini,Ali Reza Golshan,Mohammad Mohsen Mazloomfard,Abdolrasoul Mehrsai
Urology Journal , 2012,
Abstract: Purpose: To assess the accuracy of voided urine cytology versus urinary nuclear matrix protein 22 (NMP22) qualitative assay in the diagnosis of various grades and stages of recurrent bladder transitional cell carcinoma (TCC). Materials and Methods: From July 2007 to February 2009, all patients with history of superficial bladder TCC were included in this multi-center study. Each patient provided three serial voided urine samples for cytologic examination and one sample for the NMP22 qualitative assay prior to urethrocystoscopy. The sensitivity and specificity of urine cytology and the NMP22 test were determined.Results: The sensitivities of the NMP22 test and cytology for detection of recurrence were 78.8% and 44.2%, respectively (P = .001), while the specificities were 69.6% and 83.7%, respectively (P = .019). The NMP22 test showed significantly higher sensitivity than cytology in detecting recurrences in low-risk and intermediate-risk groups.Conclusion: The NMP22 assay could be used for detection of superficial bladder cancer, especially in low- and intermediate-risk groups; however, the value of the test is limited by its low specificity.
Management of Peyronie's Disease by Dermal Grafting
Mohammad Reza Nikoobakht,Abdolrasoul Mehrsai,GH Pourmand,Hooman Jaladat
Urology Journal , 2004,
Abstract: Purpose: To evaluate the results of plaque excision and dermal grafting in Peyronie’s disease. Materials and Methods: Twenty seven patients were scheduled to undergo plaque excision and dermal grafting for Peyronie’s disease. Potency, bending of erected penis, and having painful erection were evaluated in patients before and after operation. To evaluate erectile dysfunction, we used International Index of Erectile Function (IIEF) by interviewing the patients and filling questionnaires by their partners. Doppler ultrasonography was used to determine the vascular competence of penis before and after operation in 15 patients. Results: The disease was more prevalent between the ages of 40 and 60 years. Plaques were located as follows: dorsal in 18, right lateral in 6 and left lateral in 3. Mean plaque size was 11 (range 5 to 18) mm. After plaque excision and dermal grafting, penile deformity, erectile dysfunction, and painful erection had remained yet in 4 (15%) out of 27, 3 (16%) out of 19, and 3 (14%) out of 22, respectively. Doppler ultrasonographic study in 15 patients revealed improvement in peak systolic velocity (P < 0.01). In addition, a decrease in end diastolic velocity was noted also that was not significant statistically (P = 0.26). Resistive index did not improve after operation. Conclusion: This procedure showed significant improvement in penile deformity (85% of cases), erectile dysfunction (84% of cases) and painful erection (86% of cases). We recommend plaque excision and dermal grafting as an effective procedure in treating Peyronie’s disease.
Improvement of Erectile Dysfunction after Kidney Transplantation: the Role of the Associated Factors
Abdolrasoul Mehrsai,Shahram Mousavi,Mohammadreza Nikoobakht,Tina Khanlarpoor
Urology Journal , 2006,
A Giant Congenital Posterior Urethral Diverticulum Associated with Renal Dysplasia
Shahram Mousavi,Abdolrasoul Mehrsai,Mohammadreza Nikoobakht,Amir Reza Abedi
Urology Journal , 2006,
The Role of Hypothyroidism in Male Infertility and Erectile Dysfunction
Mohammad Reza Nikoobakht,Mehdi Aloosh,Nafiseh Nikoobakht,Abdolrasoul Mehrsai
Urology Journal , 2012,
Abstract: Purpose: To evaluate the effect of hypothyroidism on erectile function and sperm parameters. Materials and Methods: This study was conducted on 24 patients with hypothyroidism and 66 normal individuals. Serum levels of hormones, including thyroid stimulating hormone (TSH), thyroxin (T4), follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), and testosterone, were measured and semen analysis was done in all the participants. Erectile function was evaluated using International Index of Erectile Function (IIEF-5) questionnaire. Results: The mean IIEF-5 total score was 11.75 [95% confidence interval (CI): 9.70 to 13.79) and 20.81 (95% CI: 20.02 to 21.6) for hypothyroid group and normal subjects, respectively (P = .005). Furthermore, serum concentrations of PRL and seminal parameters were significantly different between two groups (P < .001). Conclusion: Hypothyroidism adversely affects erectile function and sperm parameters, including sperm count, morphology, and motility. In patients with sperm abnormalities and erectile dysfunction, measurement of thyroid hormones is recommended.
Urinary Tamm-Horsfall Protein and Citrate: A Case-Control Study of Inhibitors and Promoters of Calcium Stone Formation
Gholamreza Pourmand,Hamidreza Nasseh,Abdolfattah Sarrafnejad,Abdolrasoul Mehrsai
Urology Journal , 2005,
Abstract: Introduction: This study aimed to compare urinary Tamm-Horsfall protein (THP), citrate, and other inhibitors and promoters of stone formation in calcium stone formers with those in healthy individuals. Materials and Methods: From January 2002 to June 2004, 100 calcium stone formers (mean age, 38.6 ± 10.3 years) who had at least 2 episodes of calcium stone formation were compared with 100 healthy individuals (mean age, 33.8 ± 9.7 years). Their 24-hour urine THP (using the sodium dodecyl sulfate polyacrylamide gel electrophoresis method), citrate, calcium, uric acid, oxalate, and magnesium values were measured and compared. Results: The mean 24-hour urine THP was 3.3 ± 8.1 mg in patients in the study group and 4.6 ± 19.2 mg in controls (P = 0.5). However, THP in individuals with and without bacteriuria was significantly different (15.8 ± 33.6 versus 2.6 ± 10.2, P < 0.001). Mean 24-hour urinary calcium, citrate, and oxalate values were 232.6 ± 95.3 mg and 177.8 ± 82.7 mg (P < 0.001), 132 ± 103.2 mg and 395 ± 258.5 mg (P < 0.001), and 18.9 ± 22.5 mg and 10.4 ± 8.5 mg (P < 0.001) in patients in the study and control groups, respectively. There was a significant positive correlation between urinary citrate and promoters of stone formation, including urinary calcium, oxalate, and uric acid, in patients in the control group, but not in patients in the study group. Conclusion: THP in the urine of stone formers is not quantitatively different from that of healthy individuals, but it is different in patients with bacteriuria. Increased urinary excretion of calcium, oxalate, and uric acid in stone formers with no increase in urine citrate may play a role in the pathogenesis of recurrent stone formation.
Photonic Band Structures and Enhancement of Omnidirectional Reflection Bands by Using a Ternary 1D Photonic Crystal Including Left-Handed Materials
Abdolrasoul Gharaati;Z. Zare
PIER M , 2011, DOI: 10.2528/PIERM11070711
Abstract: In this paper, we use the Bloch theorem and transfer matrix method to calculate the dispersion relation of a ternary 1D photonic crystal with left-handed materials. Then, we obtain the total omnidirectional reflection band gaps of this structure. We demonstrate that the omnidirectional reflected frequency bands are enlarged in comparison with ordinary materials with positive index of refraction.
Characterization of Defect Modes in Onedimensional Ternary Metallo-Dielectric Nanolayered Photonic Crystal
Abdolrasoul Gharaati;Hadis Azarshab
PIER B , 2012, DOI: 10.2528/PIERB11101410
Abstract: We investigate the characterization of defect modes in one-dimensional ternary symmetric metallo-dielectric photonic crystal (1DTSMDPC) band-gap structures. We consider the defect modes for symmetric model with respect to the defect layer. We demonstrate reflectance with respect to the wavelength and its dependence on different thicknesses and indices of refraction of dielectric defect layer, angle of incidence and number of periods for both transverse electric (TE) and transverse magnetic (TM) waves. Also, we investigate properties of the defect modes for different metals. Our findings show that the photonic crystal (PC) with defect layer, made of two dielectrics and one metallic material, leads to different band-gap structures with respect to one dielectric and one metallic layer. There is at least one defect mode when we use dielectric or metallic defect layer in symmetric structure. And, the number of defect modes will be increased by the enhancement of refractive index and thickness of dielectric defect layer.
Analytical Calculation of Band Gap of a 1D Planar Ternary Photonic Crystal by Simulating with a Symmetric Lossless Transmission Line
Abdolrasoul Gharaati;Alireza Serajfard
PIER Letters , 2012, DOI: 10.2528/PIERL11102007
Abstract: We simulate a 1D ternary photonic crystal (TPC) employed as a clad of a photonic crystal waveguide (PCW) which consists three different lossless dielectric layers as a unit-cell. Calculating input impedance at each layer interface and using a lossless reciprocal transmission line as a model, we can predict angle intervals in which reflection occurs due to photonic crystal effect. Comparing this method with transfer matrix method and bang structure shows perfect agreement.
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