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Search Results: 1 - 10 of 2393 matches for " Abd Wahid Haron "
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Stem Cells Research and its Applications: A Review
Tooba Mirzapour,Tengku Azmi Bin Tengku Ibrahim,Mansoureh Movahedin,Abd Wahid Haron
Journal of Applied Sciences , 2011,
Abstract: Research in developmental biology has led to the discovery of different types of stem cells (totipotent, pluripotent and multipotent stem cells) that can give rise to multiple tissue types. This review summarizes a description about the stem cell concept, different type of stem cells and their potential applications. The face of extraordinary advances in the prevention, diagnosis and treatment of human diseases, devastating illnesses such as heart disease, diabetes, cancer and diseases of the nervous system, continue to deprive people of health, independence and well-being has been reviewed in this study. Stem cell research leading to prospective therapies in reparative medicine has the potential to affect the lives of millions of people around the world and there is a good reason to be optimistic. The road towards the development of an effective cell-based therapy for widespread use is long and involves overcoming numerous technical, legislative, ethical and safety issues.
Effect of Donor Cells Concentration on Colonization of Human Spermatogonial Stem Cells in Recipient Mouse Testes
Tooba Mirzapour,Mansoureh Movahedin,Tengku Azmi Bin Tengku Ibrahim,Abd Wahid Haron
Journal of Biological Sciences , 2010,
Abstract: Exogenesis (cross-species) germ cell transplantation provides an opportunity to investigate fundamental aspects of spermatogenesis. In this study, testis biopsies of patients with maturation arrest of spermatogenesis during a one year ago were first minced mechanically into small pieces and then Spermatogonial Stem Cells (SSCs) and Sertoli cells isolated by the two- step enzymatic digestion, were plated and grown on DSA-Lectin coated dishes in Dulbecco's Modified Eagle's Medium (DMEM) containing 10% fetal calf serum. Transplantation of human spermatogonial cells into mouse recipient testis was performed on day 7 (before colony formation) and 2 weeks after culturing (colony formation). The effects of different concentrations of spermatogonial cell on quantity of transplantation and percent of colonized seminiferous tubules were assayed during 8 weeks after transplantation. The result showed that SSCs can be observed on the basement membrane of the seminiferous tubules in place of spermatogonial stem cells and proliferation occurs about 4 weeks after transplantation. The difference in donor cells concentration had more effect on colonization of mouse recipient testis (p<0.05). It will be an alternative approach for the repopulation of infertile seminiferous tubules and preservation of fertility, in the future.
Haematological and Biochemical Alterations in Mice Following Experimental Infection with Whole Cell and Exotoxin (PLD) Extracted from C. Pseudotuberculosis
Abdinasir Yusuf Osman,Faez Firdaus Jesse Abdullah,Abdul Aziz Saharee,Abd Wahid Haron,Jasni Sabri,Rasedee Abdullah
Journal of Animal and Veterinary Advances , 2012, DOI: 10.3923/javaa.2012.4660.4667
Abstract: Corynebacterium pseudotuberculosis is the etiological agent of caseous lymphadenitis, a chronic infectious disease of sheep and goats. Despite the growing interest of this organism, little is known about the causality and effect of this organism on haematological and biochemical values. The purpose of this research, therefore was to determine haematological and serum biochemical features in mice inoculated with whole bacterium and exotoxin (PLD) extracted from C. pseudotuberculosis. The study was performed on apparently healthy mice of 2-3 weeks old (n = 64). The mice were divided equally into 3 groups; namely whole bacterium, exotoxin (PLD) and control group. Mice of whole bacterium group were exposed intraperitoneally to 1 mL of the inoculums containing 109 Colony-Forming Unit (CFU)/mL of live C. pseudotuberculosis. Exotoxin group were exposed intraperitoneally with a single dose of exotoxin (PLD) extracted from C. pseudotuberculosis. Mice served as a control group were challenged intraperitoneally to 1 mL of Phosphate-Buffered Saline (PBS), pH 7. Following post-infection, the mice were subjected for blood sample collection using cardiac puncture method for haematological and biochemical analysis. The results of this study revealed that there were significant decrease (p<0.05) in Hb, thrombocytes count and significant increase in WBC, neutrophils, monocytes counts in the infected group. Biochemically, there were highly significant increase (p<0.05) in the mean levels of CK, AST, ALP and ALT. The mean level of albumin in exotoxin group was significantly lower (p<0.05) compared to C. pseudotuberculosis and control groups while globulin level was significantly higher in C. pseuodotuberculosis group after 48 h. In serum electrolytes, mean level of potassium and phosphate were significantly (p<0.05) higher in infected groups compared to control group while there was no significant (p<0.05) difference in the levels of sodium, calcium and chloride. In conclusions, the present study of experimental nature showed that C. pseudotuberculosis and its exotoxin (PLD) cause disturbances in blood factors and electrolytes and pointed out that t hese haematological and biochemical alterations should be taken into account in the context of diagnosis and treatment of valuable infected hosts in order to prevent further consequences.
The Effects of PGF and CIDR on Ovarian Antral Follicular Development and Plasma IGF-1 Concentration in Goats
Muhammad Modu Bukar,Omar Mohammed Ariff,Rosnina Yusoff,Abd. Wahid Haron,Gurmeet Kaur Dhaliwal,Soh Wae Naing,Mohammed Azam Khan
Journal of Animal and Veterinary Advances , 2012, DOI: 10.3923/javaa.2011.3014.3020
Abstract: The aim of this study was to determine the effects of oestrus synchronization with PGF2α and CIDR on the ovarian antral follicle population and plasma IGF-1 concentration in goats. Daily transrectal ultrasonographic examination was conducted in 24 regularly cycling goats that were divided equally into 3 groups and oestrus synchronized with PGF2α (group A), CIDR (group B) and unsynchronized group (C). The mean number of follicles and IGF-1 concentration was significantly higher in the synchronized and subsequent natural oestrous cycles of group A and B when compared to group C. The total number of 3 mm diameter follicles were significantly higher in groups A and B compared with the control group C while the follicles that were 6 mm and larger were not significantly different (p>0.05). There was a significant low positive correlation (r = 0.14, N = 234) between IGF-1 concentration and the number of 3 mm follicles and between plasma IGF-I concentration and number of follicles (r = 0.13, N = 234). In conclusion, oestrus synchronization with PGF2α or CIDR was associated with increased plasma IGF-1 concentration and number of follicles compared with naturally cycling goats.
A method to identify potential ambiguous Malay words through Ambiguity Attributes mapping: An exploratory Study
Hazlina Haron,Abdul Azim Abd. Ghani
Computer Science , 2014,
Abstract: We describe here a methodology to identify a list of ambiguous Malay words that are commonly being used in Malay documentations such as Requirement Specification. We compiled several relevant and appropriate requirement quality attributes and sentence rules from previous literatures and adopt it to come out with a set of ambiguity attributes that most suit Malay words. The extracted Malay ambiguous words (potential) are then being mapped onto the constructed ambiguity attributes to confirm their vagueness. The list is then verified by Malay linguist experts. This paper aims to identify a list of potential ambiguous words in Malay as an attempt to assist writers to avoid using the vague words while documenting Malay Requirement Specification as well as to any other related Malay documentation. The result of this study is a list of 120 potential ambiguous Malay words that could act as guidelines in writing Malay sentences
Short-Term Field Decomposition and Physico-Chemical Transformation of Jatropha Pod Biochar in Acidic Mineral Soil  [PDF]
Cheah Poh Meng, Ahmad Husni Mohd Hanif, Samsuri Abd Wahid, Luqman Chuah Abdullah
Open Journal of Soil Science (OJSS) , 2014, DOI: 10.4236/ojss.2014.47025
Abstract:

Details regarding field decomposition and transformation of biochar in Malaysia are scarce. The objectives of this study were to investigate the physico-chemical changes experienced by Jatropha pod biochar (JPB) in acidic mineral soil under field condition. Elemental composition was determined using CHNS-O analyzer and surface area with Brunauer-Emmett-Teller (BET) method. The JPB surface chemistry and structure were studied using the Fourier Transform Infrared (FTIR) spectroscopy and 13C solid state Nuclear Magnetic Resonance (NMR) spectroscopy, respectively. The JPB short-term decomposition was investigated by using a litter bag study and decomposition data were best fitted by a hyperbolic decay model compared to an exponential decay model because no significant dry weight loss was detected after 4 months. Two phases (volatile and near stagnant) were detected for JPB field decomposition. The volatile phase was due to rapid loss of labile fraction such as carbohydrate during the initial 4 months. The near stagnant phase was probably due to adsorption of organic matter and soil minerals. The JPB was fragmented into smaller pieces, encouraging surface adsorption. Redox reaction was prominent as shown by the production of hydroxyl, carboxylic and phenolic functional groups. The JPB became more recalcitrant after 12 months of application to the soils.

Prelude to Natphoric Kansei Engineering Framework  [PDF]
Anitawati Mohd Lokman, Mohammad Bakri Che Haron, Siti Zaleha Zainal Abidin, Noor Elaiza Abd Khalid, Shigekazu Ishihara
Journal of Software Engineering and Applications (JSEA) , 2013, DOI: 10.4236/jsea.2013.612076
Abstract:

Consumers’ emotion has become imperative in product design. In affective design field, Kansei Engineering (KE) has been recognized as a technology that enables discovery of consumer’s emotion and formulation of guide to design products that win consumers in the competitive market. Albeit powerful technology, there is no rule of thumb in its analysis and interpretation process. KE expertise is required to determine sets of related Kansei and the significant concept of emotion. Many research endeavours become handicapped with the limited number of available and accessible KE experts. This work is performed to simulate the role of experts with the use of Natphoric algorithm and thus provides solution to the complexity and flexibility in KE. The algorithm is designed to learn the process by implementing training datasets taken from previous KE research works. A framework for automated KE is then designed to realize the development of automated KE system.

Effects of chemical reaction, heat and mass transfer on boundary layer flow over a porous wedge with heat radiation in the presence of suction or injection
Kandasamy R.,Abd Wahid Raj B. Md.,Khamis Azme B.
Theoretical and Applied Mechanics , 2006, DOI: 10.2298/tam0602123k
Abstract: The effect of chemical reaction, heat and mass transfer on boundary layer flow over a porous wedge with heat radiation has been studied in the presence of suction or injection. An approximate numerical solution for the steady laminar boundary-layer flow over a wall of the wedge in the presence of species concentration and mass diffusion has been obtained by solving the governing equations using numerical technique. The fluid is assumed to be viscous and incompressible. Numerical calculations are carried out for different values of dimensionless parameters and an analysis of the results obtained shows that the flow field is influenced appreciably by the chemical reaction, the buoyancy ratio between species and thermal diffusion and suction/injection at wall surface. Effects of these major parameters on the transport behaviors are investigated methodically and typical results are illustrated to reveal the tendency of the solutions. Representative results are presented for the velocity, temperature, and concentration distributions, as well as the skin friction, rate of heat transfer and mass transfer. Comparisons with previously published works are performed and excellent agreement between the results is obtained. .
Bioguided Fractionation and Purification of Natural Bioactives Obtained fromAlpinia conchigera Water Extract with Melanin Inhibition Activity  [PDF]
Zanariah Binti Ujang, Thavamanithevi Subramaniam, Mazita Md Diah, Harmayumi Binti Wahid, Badariah Binti Abdullah, Ahmad Hazri Bin Abd Rashid, David Appleton
Journal of Biomaterials and Nanobiotechnology (JBNB) , 2013, DOI: 10.4236/jbnb.2013.43033
Abstract: Crude extracts of Alpinia conchigera a species from the Malaysian Ginger (Zingiberaceae) family and its fractions obtained from various extraction methods were assayed for melanogenesis inhibition activity and cell viability. The crude extract obtained from the ethanolic extraction and the super critical fluid extraction did not exhibit significant melanin inhibition activity and was shown to be toxic to the melanocyte cells in comparison to the water extract. The crude aqueous extracts displayed melanin inhibition of 96.38 ± 1.60% and cell viability 109.90 ± 8.32% at a concentration of 500 μg/mL. Bioassay guided fractionation was performed on the water extracts to isolate the active compounds. The actives were identified as trans-cinnamaldehyde and chavicol glucopyranoside with both compound showing potent anti-melanogenesis activity. At 4.9 μg/ml, both trans-cinnamaldehyde and chavicol glucopyranoside gave 85% inhibition of melanin formation in vitro with 77% and 97% cell viability respectively. In comparison, kojic acid, a known skin lightening agent showed 90.0% inhibition at 100 μg/mL. The bioactive composition comprising the extract, active fraction, purified compounds or mixture thereof of Alpinia conchigera may be used for cosmetic and pharmaceutical applications, particularly for the purposes of reducing skin pigmentation.
Halal Traceability and Halal Tracking Systems in Strengthening Halal Food Supply Chain for Food Industry in Malaysia (A Review)
Suhaiza Zailani,Zainal Arrifin,Nabsiah Abd Wahid,Rosly Othman,Yudi Fernando
Journal of Food Technology , 2013, DOI: 10.3923/jftech.2010.74.81
Abstract: The Halal industry involves farm-to-table operations. This has led to the development of new links within the value chain most notably in the area of information technology. Given the advancement in science and technology and the on-going initiatives to improve society, it is essential that the Halal concept be fully understood by industry players as well as customers. Halal traceability system and Halal tracking system are emerging as lucrative areas in the global Halal market. An effective traceability and tracking system in Malaysia is essential to mitigate the risks associated with Halal that can disrupt the international trade of Malaysian Halal food. Traceability and tracking systems function as a tool for communication making information available along the supply chain. However, recently Malaysia s latest claim to be one of the Halal hubs in the world was put to test due to the unbelievable result of recent raid carried out by the Malaysia authorities. The finding was appalling and unethical as some so-called Halal foods manufacturers do not comply with the regulation set by the Malaysia authorities. The commotion pertaining to this issue was immense where the Muslim consumers in Malaysia began to question the effectiveness of Halal food traceability and tracking in Malaysia s market. This study is written to discuss on the approaches towards Halal traceability and tracking currently used in Malaysia. Specifically, this study discusses the conceptual architecture on Halal traceability and Halal tracking system for Halal food product in Malaysia.
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