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Search Results: 1 - 10 of 601613 matches for " A. R. Surve "
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Energy Awareness in HPC: A Survey
A. R. Surve,A. R. Khomane,S.D. Cheke
International Journal of Computer Science and Mobile Computing , 2013,
Abstract: Along with the increased awareness of energy and cost related to it, power management becomes a big issue for high performance computing. Power control is becoming a key challenge for effectively operating a modern high end computing infrastructures such as server, clusters, data centers and Grids. In addition to reducing operating costs, precisely controlling power consumption is an essential aspect in thefield of High performance computing. Building energy efficient computer infrastructure is next major goal of the high performance computing. In recent years many researchers have been taking keen interest into developing sustainable, energy efficient high performance architecture. We, in this paper we are surveying energy efficient techniques for cluster computing and try to classify these techniques.
Role of Oxidants and Anti Oxidants in Patients with Cardiovascular Diseases
Ujjwala Jayant kulkarni,Seema L. Jaw alekar; Vasant T. Surve and Y.A. Deshmukh
Asian Journal of Medical Sciences , 2010,
Abstract: Over the last two decades, it has become increasingly clear that reactive oxygen species (ROS), including free radicals are involved in cardiovascular diseases. In recent years, there has been a growing interest in the clinical implications of these oxidants. The ROS are common by-products of many oxidative biochemical and physiological processes. Therefore the present study was carried out to evaluate the total antioxidant capacity, lipid peroxidation and status of superoxide dismutase in patients with cardiovascular diseases. Total 185 patients of both sexes were included in the study and further classified into 3 groups as hypertensive, Ischemic heart disease and cerebrovascular disease/stroke. The 60 healthy subjects who were not on any kind of prescribed medication or dietary restrictions were included in the control group. MDA is estimated as a marker of lipid peroxidation, levels were significantly increased in all groups than controls (p<0.001). Superoxide dismutase and glutathione reductase activities was significantly low er in all groups than control (p<0.001), GPX levels were decreased in all groups except hypertension (p<0.001), NO level were decreased in all the groups except cerebrovascular disease / stroke when compared to the control. Significantly lower level of total antioxidant capacity and prominent scavenger of superoxide anion radicals suggests that failure of antioxidant defense mechanism against oxidative stress may be an important factor in the pathogenesis of cardiovascular diseases.
Maternal Mortality A Challenge?
Varsha N. Patil,M. A. Shinde,Meenakshi Surve,Shital G. Sonone
Journal of Krishna Institute of Medical Sciences University , 2013,
Abstract: Background : The current maternal mortality rate (MMR) in Maharashtra is 104/100000 live births, ranking 3rd in India. There is scope for reducing it as majority of the causes of MMR are preventable and curable. Aims and Objectives: To study the sociodemographic profile and causes of maternal deaths at Dr. V. M. Govt. Medical College, Solapur. Material and Methods: The study population included all deliveries i.e. women admitted in the hospital during pregnancy, child-birth or within 42 days of termination of pregnancy from any cause related to or aggravated due to pregnancy during the period of 2 years from 1st August 2009 to 31st July 2011. IPD case records and autopsy reports of all maternal deaths were taken and various variables were studied. The present study is prospective study of maternal mortality conducted in Dept. of Obstetrics and Gynaecology, Dr. V. M. Medical College Solapur. Cases were distributed ac-cording to their age, literacy rate, residence,socioeconomic status, ante-natal care, gestational age, gravida/parity, place of referral, pregnancy outcome, and place of delivery, perinatal outcome and etiological factors. This study also suggests the measures to reduce maternal mortality. Results: The total number of live births during the study period were 13,188 and total number of maternal deaths were 63 and MMR was 477 per 1, 00,000 live births. In the maternal deaths studied, 1/3rd of the women were illiterate, half of the women belonged to urban slum areas and of lower socioeconomic class.1/3rd of the deaths occurred in primigravida,within 24 hrs from admission, 58.73% of the patients were referred from outside. Out of that 86.49% of women were sent from private hospital and died in post partum period, having poor perinatal outcome. Haemorrhage (28.57%) and hypertension (12.69%) are two direct causes and severe anemia (33.33%) is most common in direct cause of maternal death in our study.
Novel nasal In situ gelling system for treatment of sinusitis
Mehta M,Surve S,Menon M
Indian Journal of Pharmaceutical Sciences , 2009,
Abstract: In situ gelling systems based on temperature-dependent phase transition containing pheniramine and phenylephrine were developed using combination of Poloxamers, different cellulose polymers (HPMC) and xanthan gum. The formulations were tested for in vitro gelation, appearance, pH, drug content, in vitro drug release, mucoadhesive strength, preservative efficacy and stability. In vitro release studies revealed significant prolonged released of both drugs up to 24 h as against only 2 h with drug solution. Formulations were found to stable over period of 3 months. In vivo nasal residence time of in situ gel by gamma scintigraphy was found to be significantly higher (6 h) in comparison to drug solution (15 min). It can be concluded that Poloxamers in combination with HPMC are suitable to develop stable, safe in situ temperature-based mucoadhesive gelling systems with prolonged nasal residence time.
Effect of Sulphaphenazole on Pathogenic Microorganism Klebsiella aerogenes
Neeta N Surve,Uttamkumar S Bagde
International Journal of Biology , 2011, DOI: 10.5539/ijb.v3n2p106
Abstract: The inhibitory action of Sulphaphenazole on pure culture of Klebsiella aerogenes was studied with emphasis on the mode of action of the drug. Sensitivity was studied by broth dilution method and by Hi-Comb Method. The Minimum Inhibitory Concentration (MIC) of Sulphaphenazole determined by broth dilution method and Hi-Comb Method against Klebsiella aerogenes was 30 ?g/ml. Sulphaphenazole induced changes in bacteria which interfered with cell wall synthesis revealing morphological alterations that was shown by Scanning Electron Microscopy (SEM). The present studies were undertaken to investigate the presence and characteristic alterations in surface morphology of cells resulting from the action of Sulphaphenazole known to interfere with intracellular protein synthesis. The morphological abnormalities observed may be surface reflections of specific abnormalities of intracellular protein synthesis or may represent a final common pathway of drug-induced injury at many sites within or on bacterial cells. As the activity of dehydrogenases was inhibited by Sulphaphenazole, cells were incapable of oxidizing substrate. It resulted in limited supply of energy rich compounds such as ATP that affected the synthesis of macromolecules. Ultimately multiplication and growth of the organism got ceased.
Arsenic toxicity in pathogenic Staphylococcus epidermidis and Klebsiella pneumoniae
Neeta N Surve,Uttamkumar S Bagde
International Journal of Biology , 2010, DOI: 10.5539/ijb.v2n2p213
Abstract: The sensitivity of pure cultures of Staphylococcus epidermidis and Klebsiella pneumoniae towards arsenic was studied with particular reference to biochemical changes induced by the heavy metal in these organisms. Arsenic strongly inhibited the growth and viability of both the organisms. Addition of arsenic prolonged the lag phase and this was found to be the concentration dependent phenomenon. The Minimum inhibitory concentration (MIC) determined was 200 ppm and 20 ppm in S. epidermidis and K. pneumoniae respectively that inhibited growth, synthesis of protein, DNA, RNA completely and activity of dehydrogenases of the TCA cycle. In S. epidermidis and K. pneumoniae, cell wall, membrane and cytoplasm 24.5%, 32.5%, 43% and 20%, 35%, 45% arsenic respectively got incorporated. As the activity of dehydrogenases was inhibited by arsenic, cells were incapable of oxidizing substrate. It resulted in limited supply of energy rich compounds such as ATP that affected the synthesis of macromolecules. Ultimately multiplication and growth of the organism got ceased.
Computer Automation for Malaria Parasite Detection Using Linear Programming
International Journal of Advanced Research in Electrical, Electronics and Instrumentation Engineering , 2013,
Abstract: In this project, we introduce a new approach to represent a mathematical modeling technique by means of linear programming as an efficient tool to solve problems related to medical imaging problems related to Malaria Diagnosis through Microscopy Imaging problems. Two applications are approached: (1) Formulation of a linear programming model based on the given data, (2) Solving and displaying the result using graphical method approach for detecting parasite. The application mainly consists of developing a linear mathematical model from the collected information and in addition to it, the problem is solved by Graphical approach. By this we mark the region infected with malaria from the original image which leads to identifying parasite. By observation of graph it can be predict whether the blood is infected by parasite or not. The species of parasite infected the erythrocytes can also be classified and parasite can be identified by labeling the infected area.
Toxicity of Oxazolidinone Linezolid on Pathogenic Microorganism Listeria ivanovii
Neeta N Surve,Uttamkumar S Bagde
International Journal of Biology , 2011, DOI: 10.5539/ijb.v3n4p72
Abstract: Oxazolidinone, a new class of antimicrobial agents is active against various Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis (MRSE), penicillin-resistant Streptococcus pneumoniae (PRSP) and vancomycin-resistant Enterococci (VRE). Sensitivity of Oxazolidinone Linezolid was studied against pathogenic microorganism Listeria ivanovii and Minimum Inhibitory Concentration (MIC) determined by broth dilution method and Hi-Comb method was 10 μg/ml. Morphological alterations on Listeria ivanovii cell surface were seen by Scanning Electron Microscopy (SEM) after treatment with Linezolid. Inhibition on the activity of dehydrogenases of organism by Linezolid was also studied in the present study.
Diagnosis and prevalence of bacterial vaginosis.
Saharan S,Surve C,Raut V,Bhattacharya M
Journal of Postgraduate Medicine , 1993,
Abstract: A prospective study of 80 women was undertaken to estimate the prevalence of bacterial vaginosis, and to compare two methods of diagnosing the condition. Bacterial Vaginosis was detected by both Gram stain and compound criteria in 30 women. The prevalence was 37.5%. Gram stain provides a simple and inexpensive method for laboratory confirmation of bacterial vaginosis where facilities for using the compound criteria are not available.
Clinical and Autoimmune Profile of Scleroderma Patients from Western India
Vandana Pradhan,Anjali Rajadhyaksha,Milind Nadkar,Pallavi Pandit,Prathamesh Surve,Maxime Lecerf,Jagadeesh Bayry,Srinivas Kaveri,Kanjaksha Ghosh
International Journal of Rheumatology , 2014, DOI: 10.1155/2014/983781
Abstract: Background. Systemic sclerosis (SSc, scleroderma) is a disorder characterized by fibrosis of skin and visceral organs. Pathogenesis of scleroderma is complex and is incompletely understood as yet. Autoantibodies in SSc represent a serologic hallmark which have clinical relevance, with diagnostic and prognostic potential. Objectives. To study distribution of clinical manifestations and to identify frequency of autoantibodies among subtypes of scleroderma patients from Western India. Methodology. One hundred and ten scleroderma patients were clinically classified according to the American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) criteria. All these patients were in active stage of disease. Clinical manifestations were recorded at the time of presentation. Autoantibodies were tested in them by indirect immunofluorescence test and ELISA. Immunoglobulin levels were estimated by nephelometer. These parameters were further correlated with clinical presentation of the disease. Results. Scleroderma patients had M?:?F ratio of 1?:?10 where mean age at evaluation was years and a mean disease duration was months. Clinical subtypes showed that 45 patients (40.9%) had diffused cutaneous (dcSSc) lesions, 32 patients (29.1%) had limited cutaneous (lcSSc) lesions, and 33 patients (30%) had other autoimmune overlaps. The overall frequency of ANA in SSc patients studied was 85.5%. The frequency of anti-Scl70, anti-centromere, anti-endothelial cell antibodies (AECA), and anti-keratinocyte antibodies (AKA) was 62.7%, 22.7%, 30%, and 40.9%, respectively. Anti-Scl70 antibodies were significantly high (75.6% versus 46.9%) among dcSSc patients () whereas anti-centromere antibodies were significantly high (9% versus 38%) among lcSSc patients when these two subtypes were compared (). Conclusion. This study supports that there are geoepidemiological variations among scleroderma patients for their clinical presentation, autoantibody profile, and immune parameters across the country. 1. Introduction Scleroderma or systemic sclerosis (SSc) is a complex autoimmune disease affecting 1/100,000 individuals among the Caucasian population. The prevalence rate of this disease is around 5/100,000 with an incidence of 1/100,000. Higher rates have been reported in USA, Australia, and Eastern Europe and lower rates have been reported in Northern Europe and Japan [1]. Even though current clinical and diagnostic utilities have led to a better understanding of the disease, its pathogenesis still remains unknown. Scleroderma is a heterogeneous disease with a wide range
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