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Search Results: 1 - 10 of 464309 matches for " A. Jain "
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Metformin: "Old warrior for a new battle"
Jain A
Indian Journal of Cancer , 2010,
Phase 0 (Zero) clinical trials: A myth or reality?
Jain A
Indian Journal of Cancer , 2010,
Mucoadhesive chitosan microspheres for non-invasive and improved nasal delivery of insulin
Jain S,Jain Nitin,Gupta Y,Jain A
Indian Journal of Pharmaceutical Sciences , 2007,
Abstract: Novel mucoadhesive chitosan microspheres were developed to explore the possibilities of non invasive delivery of insulin. The mucoadhesive chitosan microspheres were prepared by emulsification method. Formulations were characterized for various physiochemical attributes, shape, surface morphology, size and size distribution, drug payload, swelling ability and mucoadhesion. Mucoadhesive chitosan microspheres bearing insulin were evaluated for in vitro drug release and in vitro drug permeation through mucosal membrane. In vivo performance was studied on blood plasma level of glucose. Glutaraldehyde cross-linked microspheres showed better reduction of blood glucose level than citric acid cross-linked microspheres. The in vivo performance of mucoadhesive microspheres showed prolonged and controlled release of drug as compared with the conventional dosage form.
Compatible maps and fixed points in 2 non-Archimedean Menger PM-space
B. Singh,A. Jain,M. Jain
International Journal of Contemporary Mathematical Sciences , 2012,
A prepaid meter using mobile communication
A Jain, M Bagree
International Journal of Engineering, Science and Technology , 2011,
Abstract: Energy meters in India have dominantly been electromechanical in nature but are gradually being replaced by more sophisticated and accurate digital and electronic meters. A high percentage of electricity revenue is lost to power theft, incorrect meter reading and billing, and reluctance of consumers towards paying electricity bills on time. Considerable amount of revenue losses can be reduced by using Prepaid Energy Meters. A prepaid energy meter enables power utilities to collect energy bills from the consumers prior to the usage of power by delivering only as much as what has been paid for. This paper suggests a prepaid energy meter behaving like a prepaid mobile phone. The meter contains a prepaid card analogous to mobile SIM card. The prepaid card communicates with the power utility using mobile communication infrastructure. Once the prepaid card is out of balance, the consumer load is disconnected from the utility supply by the contactor. The power utility can recharge the prepaid card remotely through mobile communication based on customer requests. A prior billing is bound to do away with the problems of unpaid bills and human error in meter readings, thereby ensuring justified revenue for the utility. The proposed prepaid meter is implemented in a software model and Matlab has been used for simulation.
Solid state fermentation studies of citric acid production
A Kumar, VK Jain
African Journal of Biotechnology , 2008,
Abstract: Treated sugarcane bagasse supplemented with sucrose medium was found 1.7 fold (citric acid based on sugar consumption) better substrate than untreated bagasse carrier. The performance of packed bed reactor at aeration rate of 0.75 l/min and apparent packing density of 35.0 g/l was superior with citric acid yield of 55.90% (w/w), overall productivity of 0.087 g/100 g DS.h and specific growth rate of 0.055 h-1. However, in flask fermentation citric acid yield of 41.56% (w/w) with overall productivity of 0.064 g/100 gDS.h and specific growth rate of 0.043 h-1 was observed. The system confirmed that citric acid production was Type-II fermentation. Citric acid recovery of 90.39% (w/w) was achieved from fermented broth.
Myotonic dystrophy: a retrospective diagnosis
D Jain, A Chakravarty
Southern African Journal of Anaesthesia and Analgesia , 2012,
Abstract: Myotonic dystrophy is not commonly encountered in anaesthetic practice and its existence in a patient can easily go undetected, leading to intraoperative and postoperative complications. We report a case of a 45-year-old female without any typical features of myotonic dystrophy, who presented at our hospital for a laparoscopic cholecystectomy. Postoperatively, on account of a delayed recovery, she was diagnosed with myotonic dystrophy.
Formulation and Characterization of Sustained Release Floating Microballoons of Metformin Hydrochloride
A Yadav, DK Jain
Tropical Journal of Pharmaceutical Research , 2012,
Abstract: Purpose: To formulate sustained release gastroretentive microballoons of metformin hydrochloride with the objective of improving its bioavailability. Methods: Microballoons of metformin hydrochloride were formulated by solvent evaporation and diffusion method using varying mixtures of hydroxypropyl methylcellulose (HPMC) and ethyl cellulose (EC) polymers. The balloons were characterized for particle size, surface morphology, incorporation efficiency, floating behavior and in vitro drug release. Results: The mean particle size of the formulated microballoons was in the range of 34.2 ± 4.7 to 95.7 ± 2.2 μm. Incorporation efficiencies of over 83.8 ± 0.9 % were achieved for the optimized formulations. Most of the formulations were buoyant with maximum buoyancy of 81.4 ± 2.0 % for > 12 h, showing good floating behavior of microballoons. Release kinetic data showed best fit to the Higuchi model, indicating that diffusion was the predominant mechanism of drug release. Conclusion: Microballoons is a potential suitable delivery system for sustained release of metformin hydrochloride with improved bioavailability when compared with conventional dosage forms of the drug.
Yadav A,Jain DK
Journal of Drug Delivery and Therapeutics , 2011,
Abstract: Albumin microspheres (AMS) have found many applications in the diagnosis and treatment in recent years and more than 100 diagnostic agents and drugs have been incorporated into AMS. In the present study Bovine Serum Albumin (BSA) based microspheres bearing propranolol hydrochloride were prepared by an emulsion-internal phase stabilization technique. The prepared microspheres were studied for particle size distribution, drug loading, release characteristics, bioadhesion andin-vitro controlled diffusion across the rat intestine. The microspheres had mean diameter between 1-25 μm of which more than 50 percent were below 5 μm. The encapsulated drug was found to be about 9% w/w of that initially added to microspheres and the superficial drug was 25% of the total amount of the encapsulated drug. Also AMS were noted to possess good bioadhesion in such a way that about 70% of microspheres remained adherent on the surface mucosa of rat jejunum. The drug release from albumin microspheres was mainly controlled by diffusion and showed a biphasic pattern with a high initial release (burst effect), followed by a more gradual terminal release. The total amount of drug released from microspheres after 12h was 70%. In-vitro experiments on the rat intestinal segments revealed that the microspheres could effectively pass their content through intestinal membrane.
Skylight Light Intensity Data Logging System
A. Udina,Lc Jain
Active and Passive Electronic Components , 1997, DOI: 10.1155/1997/61913
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