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Search Results: 1 - 10 of 563235 matches for " A. E. Bawazir "
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Chronic effect of olive oil on some neurotransmitter contents in different brain regions and physiological, histological structure of liver and kidney of male albino rats  [PDF]
A. E. Bawazir
World Journal of Neuroscience (WJNS) , 2011, DOI: 10.4236/wjns.2011.13005
Abstract: Olive oil is an important source of mono-unsaturated fat and a prime component of the Mediterranean diet. The beneficial health effects of olive oil are due to both its high content of mono-unsaturated fatty acids and its high content of anti-oxidative substances. The objective of this study was to investigate the basis for the epidemiological information relating to the health benefits associated with the consumption of ex-tra-virgin olive oil (EVOO). The effect of olive oil on norepinephrine (NE), dopamine (DA), serotonin (5-HT) and gamm-aminobutyric acid (GABA) con-tents in different brain regions and histological structure of liver and kindey of male albino rats was studied. The chronic administration of olive oil (7.5 mg/kg body wt.) caused a significant increase in norepinephrine (NE), dopamine (DA) , serotonin (5-HT) and gamm-aminobutyric acid (GABA) con-tent in different brain regions (Cerebellum, striatum, cerebral cortex, hypothalamus, brain steam and hip-pocampus) of male albino rats. The increase in NE, DA, 5-HT, and GABA content in the different CNS areas of male albino rat may be due to the inhibition of Ca2+/calmodulin binding which plays an important role in the release of these neurotransmitters. The results, also, revealed that urea and creatinne con-centrations in rats with oral administration with olive oil were decreased. Meanwhile, the activities of the enzymes AsT, AlT and ALP were elevated. The pre-sent results indicated that there is no change in tis-sues of kidney after treated with virgin olive oil. Olive oil may potentially be safe for use as a sedative drug. improvement also led to the reductions in risk of Alzheimer’s and Parkinson’s diseases.
Synthesis of Some New Thioethers and 4-Thiazolidinones Bearing 3-(Pyridine-4'-yl)-1,2,4-Triazino[5,6-b]Indole Moiety as Antifungal Agents  [PDF]
Wafa A. Baker Bawazir
International Journal of Organic Chemistry (IJOC) , 2019, DOI: 10.4236/ijoc.2019.91004
Abstract: Some new asymmetric thioethers 5 and 4-thiazolidinones 6 have been obtained from condensation of 5-formyl-3-(pyridin-4'-yl)-1,2,4-triazino[5,6-b] indole (3) with halogenated aromatic amines followed by addition of thiophenol and/or cycloaddition with thiolactic acids in nonpolar solvents. Structures of the products confirmed by elemental analysis and spectral measurements. The new systems obtained were evaluated as antifungal agents.
Various Routes to Synthesise 3-Thioxo-1,2,4-Triazine-5-One Derivatives as Antimicrobial Agents  [PDF]
Reda M. Abdel-Rahman, Wafa A. Bawazir
International Journal of Organic Chemistry (IJOC) , 2018, DOI: 10.4236/ijoc.2018.82014
Abstract: A simple condensation afforded some new 3-thioxo-1,2,4-triazin-5-one derivatives (4, 6 and 8). Utilizing a facile condensation of (E)-4-(4’-bromo styryl)-2-oxo-3-buteneoic acid with thiosemicarbazide, dithioic formic acid hydrazide, and thiocarbahydrazide in different conditions. Structures of these compounds were confirmed by elemental and spectral analysis. The preliminary biocidal activity of these products were evaluated against some microbial and compared to Mycostatine and piperacillin as antibiotics were most of derivatives exhibited good activity.
Synthesis of New Fluorinated Amino-Heterocyclic Compounds Bearing 6-Aryl-5-Oxo-1,2,4-Triazin-3-Yl Moiety as Antimicrobial Agents  [PDF]
Wafa A. Bawazir, Reda M. Abdel-Rahman
International Journal of Organic Chemistry (IJOC) , 2018, DOI: 10.4236/ijoc.2018.84027
Abstract: Some more new fluorine substitutedamino compounds bearing 6-aryl-5-oxo-1,2,4-triazin-3-yl moieties and its derivatives 3 - 7 have been synthesised successfully from aroylation of 6-(2’-aminophenyl)-3-thioxo-1,2,4-triazin-5-one (1), followed by fluoro amination with 4-fluoroanilinein Abs EtOH and then treated with ammonia/EtOH and finally acylation/aroylation or cyclocondensation reactions with malonic acid in AcOH. Structure of the products has been established upon elemental analysis and their spectral measurements. All the obtained compounds evaluated as antimicrobial agents were the compounds which contained both nitro and fluorine elements and exhibited a highly activity the other derivatives.
Plant based native therapy for skin problems in Aurangabad district (M.S.)
I.H. Zahid,A.S. Bawazir,Rafiuddin Naser
Journal of Pharmacognosy and Phytochemistry , 2013,
Abstract: An Ethnobotanical survey was carried out to collect information on the use of medicinal plants by the local and tribal people of some selected areas of Aurangabad district of Maharashtra state. A total of 26 plants have been recorded here which are used for curing 20 types of skin problems (Dermatological problems), such as boils, eruption, cuts, wounds, eczema, syphilis, urticaria etc. The data was collected by using questionnaire approach, group discussion and contact with traditional healers of the villages.The investigated plant taxa have been listed according to their uses in curing the diseases, along with botanical names, families, local names, parts used and routes of administration. Some noteworthy medicinal plants are Hydnocarpus pentandra, Murraya koenigii, Tagetes erecta, Withania somnifera, Sapindus trifoliatus, Rauwolfia serpentine, Centella asiatica, Eclipta alba etc.
Studies on Solubility, Bioavailability and Hypoglycemic Activity of Gliclazide β-cyclodextrin Complexes
Hisham S. Abou-Auda,Saleh A. Bawazir,Yousef A. Asiri,Othman A. Gubara
International Journal of Pharmacology , 2006,
Abstract: The effect of beta-cyclodextrin (β-CD) complexation with gliclazide (Gz) on both pharmacokinetic and hypoglycemic parameters of pure drug was evaluated and correlated with its in vitro dissolution. The study involves the preparation of solid inclusion complex of Gz with β-CD using different techniques. The prepared binary systems showed significant enhancement for in vitro dissolution. The pharmacokinetics of neutralization complex (equivalent to 30 mg of gliclazide) was studied in beagle dogs. Gliclazide plasma levels were measured over a period of 48 h from dosing, using a sensitive HPLC method. Significant changes were observed in the mean values of Gz pharmacokinetic parameters (Cmax, Tmax and AUCo-oo) between the control and pre-treated groups. The findings of this study suggest that neutralization complex in 1:1 and 1:2 Gz/β-CD molar ratios was the best in enhancing gliclazide dissolution characteristics and bioavailability. Moreover, the various measures of bioavailability (except AUC) correlated well with both in vitro tests and hypoglycemic activity.
Persuasive Technology Contributions Toward Enhance Information Security Awareness in an Organization
Hani A. Qudaih,Mohammed A. Bawazir,Shuaibu Hassan Usman,Jamaludin Ibrahim
Computer Science , 2014, DOI: 10.14445/22312803/IJCTT-V10P131
Abstract: Persuasion is part and parcel of human interaction. The human persuaders in society have been always exit, masters of rhetoric skilled of changing our minds, or at least our behaviors. Leaders, mothers, salesmen, and teachers are clear examples of persuaders. Persuaders often turn to technology and digital media to amplify their persuasive ends. Besides, our lives and how we lead them influenced by technologies and digital media,but for the most part, their effects on our attitudes and behaviors have been incidental, even accidental. Although, nowadays, the use of computers to sell products and services considered as the most frequent application of persuasive technology. In this short paper, based on an extensive review of literatures, we aim to give a brief introduction to persuasive technology, and how it can play a role and contribute to enhance and deliver the best practice of IT. Some challenges of persuasive technology have been discussed. At the end, some recommendations and steps should be taken place to empower IT professional practices have been listed.
Synthesis of Some More Fluorine Heterocyclic Nitrogen Systems Derived From Sulfa Drugs as Photochemical Probe Agents for Inhibition of Vitiligo Disease-Part I
Reda M. Abdel-Rahman,Mohammad Saleh I. T. Makki,Wafa A. Bawazir
Journal of Chemistry , 2011, DOI: 10.1155/2011/586063
Abstract:
Synthesis of Fluorine Heterocyclic Nitrogen Systems Derived From Sulfa Drugs as PhotochemicalProbe Agents for Inhibition of Vitiligo Disease-Part II
Reda M. Abdel-Rahman,Mohammad Saleh I. T. Makki,Wafa A. Baker Bawazir
Journal of Chemistry , 2010, DOI: 10.1155/2010/467564
Abstract:
A Generalized Permanent Estimator and its Application in Computing Multi-Homogeneous Bézout Number
Hassan M.S. Bawazir,Ali Abd Rahman,Nor’aini binti Aris
Research Journal of Applied Sciences, Engineering and Technology , 2012,
Abstract: The permanent of a matrix has many applications in many fields. Its computation is #P-complete. The computation of exact permanent large-scale matrices is very costly in terms of memory and time. There is a real need for an efficient method to deal well with such situations. This study designs a general algorithm for estimating the permanents of the complex square or non-square matrices. We prove that the Multi- Homogeneous Bézout Number (MHBN) can be estimated efficiently using the new algorithm. Further, a proposition that provides some analytic results is presented and proved. The analytic results show the effectiveness and the efficiency of our algorithm over some recent methods. Furthermore, with the new algorithm we can control the accuracy as we need. A large amount of numerical results are presented in this study. By applying the algorithm that estimates MHBN we extend the applicability of the algorithm.
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