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Search Results: 1 - 10 of 476308 matches for " A. Bajaj et al. "
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A. Bajaj et al.
International Journal of Pharmaceutical Sciences and Research , 2012,
Abstract: Rifampicin and Isoniazid microcapsules were prepared by phase seperation coacervation method for inclusion in suspension formulations. Ethyl cellulose was used as the coating material for microencapsulation. Developed microcapsules were characterized for visual appearance, photomicrography, sieve analysis, drug content, bulk density, ethyl cellulose content and drug release studies. Microcapsules were found to be irregular in shape, free flowing with wide particle distribution in the range of 178-422 μm with 75 % drug content. Both Rifampicin and Isoniazid microcapsules exhibited prolonged release with first order kinetics. Rifampicin and Isoniazid microcapsule suspension formulation was characterized for pH, viscosity, sedimentation rate and drug content. The developed suspension was found to be uniform with drug content between 99-100%. Stability studies indicated that Rifampicin and Isoniazid suspension formulation exhibited greater stability as compared to pure drug suspensions. Hence, Rifampicin and Isoniazid suspension exhibits a potential to be developed as controlled release paediatric and geriatric formulation.
Seroprevalences of HBV, HCV and HIV among Children who examined Before Elective Surgery in Mardin province
Tekin A et al.
Konuralp Tip Dergisi , 2011,
Abstract: Objectives: The aim of this study was to investigate the seroprevalence of hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) among children who examined before elective surgery in Mardin province. Materials and Methods: Between 01 November 2008 and 30 April 2010, a total of 556 patients aged 0–16 years, who planned to be operated, were investigated for viral hepatitis seroprevalences in the Mardin Women and Pediatrics Hospital. Children’s blood samples were tested for hepatitis B surface antigen (HBsAg), hepatitis B surface antibody (anti-HBs), HCV antibody (anti-HCV) and HIV antibody (anti-HIV) markers by chemiluminescent immunoassay with Advia Centaur (Siemens) autoanalyser. Results: A total of 556 children (441 boys, 115 girls) age under 16 years who planned to be underwent elective surgery were included. We found positive HBsAg and negative anti-HBs in 3 patients (0.5%); Negative HBsAg and positive anti-HBs were found in 473 children (85.1%); Negative HBsAg and negative anti-HBs were observed in 80 children (14.4%). None of the patients had positive HCV and HIV antibody. Conclusion: HBsAg positivity rate was lower and anti-HBs positivity rate was higher than expected levels. This study indicated that vaccination was successful in our region.
Erythrocytes Sedimentation Rate and Clinical Use
Kutlucan A et al.
Konuralp Tip Dergisi , 2012,
Abstract: Measuring acute phase response helps us diagnose and follow up diseases. Erythrocytes Sedimentation Rate (ESR) among those measurements is a biochemical method which is commonly used. Roll formation or clustering of erythrocytes determines of sedimentation rate, and main factors affecting those events are fibrinogen, α 2 , β and γ globins. Moreover, some conditions such as ratio between plasma and erythrocytes, plasma viscosity, tube used for measuring in sedimentation rate, room temperature and anti-coagulant agent used affect Erythrocyte sedimentation rate measurement. It can be elevated in several pathological conditions as well as in pregnancy, senility and menstruation. ESH gives general idea or information as pulse and body temperature do; it is elevated in several severe diseases, it can be course in normal levels. In this review, it was aimed to present its use of clinical practice, definition, measurement methods, and factors affecting ESH.
Retrospective Investigation of Complications in Nineteen Hundred Cases of Circumcision
?zkan A et al.
Konuralp Tip Dergisi , 2012,
Abstract: Aim: To define the complications which were seen after the circumcisions performed in our clinic and to present the complication rates. It was also aimed to compare our complications with the complication rates in our country in the light of the literature knowledge.Materials and Method: In this study, circumcision was performed to 1916 child patients who were referred to our clinic in between July 2007 and September 2009. 16 patients with glandular hypospadias with intact prepisium and normal appearance were not included to the study. Early and late complications after circumcisions were evaluated retrospectively.Results: Median age of 1900 boys who were included the study was 6.66±2.12 (0-17 years). Complication rate in our study was 5%. In our study, hemorrhage was the leading complication with 3.15%. Other complications included infection with 0.52%, adherence of mucosa or skin to the glans with 0.47%, and complications related to anesthesia or local anesthesia with 0.42%.Conclusions: Circumcision is a surgical procedure, and it needs maximum care as every surgical procedure does, with rules that must be obeyed, and also the proper technique must be used. Undesirable results can be seen after circumcision, as well. It is the duty of the physicians to try to prevent the unpredicted results and complications.
Determinants of Anxiety among Mothers of Infants in the Newborn Intensive Care Unit: Role of Family Physicians on Coping with the Stressors
Uluda? A et al.
Konuralp Tip Dergisi , 2012,
Abstract: Aim: In this study, it was aimed to establish the stressing factors and expectations of mothers from newborn intensive care unit (NICU) staff and the complimentary role of family physicians on maternal coping with the stress. Methods: Study was conducted in 78 mothers of NICU patients in Eskisehir Osmangazi University. Socio-demographic characteristics and prenatal, follow up of pregnancy and postnatal period were recorded. General health questionnaire and The State-Trait Anxiety Inventory were assessed. Results: The most common reason for infants to be admitted to the NICU was prematurity. Mothers’ psychological stress levels depend on so many variables. There were 41 mothers who visit and hold their babies effects depresssion and anxiety and as the hospital stay prolonged and gestational age decreased, mothers’ anxiety and depression increased. High anxiety related factors among the mothers were appearance of their small, fragile baby. When mothers’ educational status was higher, depression and anxiety levels decreased. Maternal age did not affect anxiety levels and depression. Presence of abortions or stillbirth in previous pregnancies increased mothers state anxiety levels. Conclusion: Birth of a premature infant or an infant with congenital anomaly is to be seen as an ongoing traumatic life event, where psychotherapeutic support is to be recommended. In Turkey family practice application has been established. Family physicians after the birth, of a high risk infant; mothers and babies follow-up plan could be coordinated and because of increased frequency of mothers’ anxiety and acute mental disorders, family physician should follow the families at close range this period of time.
Vaginal Leiomyoma in Pregnancy: A Case Report
Karata? A et al.
Konuralp Tip Dergisi , 2011,
Abstract: Vaginal leiomyoma is a rare, benign tumor with variable clinical presentations. Vaginal leiomyoma usually arises in the midline anterior wall. Like uterine leiomyomas, vaginal leiomyomas occur most frequently between the ages of 35 and 50 years. Depending on the size and location, vaginal leiomyomas may produce diverse clinical symptoms, such as dyspareunia, pain, or dysuria. We report a case of a vaginal leiomyoma, diagnosed in a 39 weeks pregnant 25-years-old woman suffering from dyspareunia and surgically excised three mounts after cesarean section.
Nanostructures in environmental pollution detection, monitoring, and remediation
A. Vaseashta et al
Science and Technology of Advanced Materials , 2007,
Abstract: We present preliminary results of our joint investigations to monitor and mitigate environmental pollution, a leading contributor to chronic and deadly health disorders and diseases affecting millions of people each year. Using nanotechnology-based gas sensors; pollution is monitored at several ground stations. The sensor unit is portable, provides instantaneous ground pollution concentrations accurately, and can be readily deployed to disseminate real-time pollution data to a web server providing a topological overview of monitored locations. We are also employing remote sensing technologies with high-spatial and spectral resolution to model urban pollution using satellite images and image processing. One of the objectives of this investigation is to develop a unique capability to acquire, display and assimilate these valuable sources of data to accurately assess urban pollution by real-time monitoring using commercial sensors fabricated using nanofabrication technologies and satellite imagery. This integrated tool will be beneficial towards prediction processes to support public awareness and establish policy priorities for air quality in polluted areas. The complex nature of environmental pollution data mining requires computing technologies that integrate multiple sources and repositories of data over multiple networking systems and platforms that must be accurate, secure, and reliable. An evaluation of information security risks and strategies within an environmental information system is presented. In addition to air pollution, we explore the efficacy of nanostructured materials in the detection and remediation of water pollution. We present our results of sorption on advanced nanomaterials-based sorbents that have been found effective in the removal of cadmium and arsenic from water streams.
Abordagem fisioterapêutica no tratamento de uma crian a anéfrica: relato de caso = Physioterapheutic strategy in the treatment of a anephric child: Case report
Rocha, A. et al.
Scientia Medica , 2005,
Abstract: Objetivo: Relatar o caso de uma crian a anéfrica, que foi submetida a tratamento de fisioterapia respiratória e motora, durante a sua interna o hospitalar. Método: Neste relato de caso uma crian a de onze meses, do sexo masculino, anéfrica, foi avaliada antes de ser submetida ao tratamento fisioterapêutico e dois meses após este tratamento. O instrumento utilizado para avaliar o desenvolvimento neuropsicomotor (DNPM) foi a escala de Denver e para avaliar a melhora do quadro respiratório foram analisados os sinais vitais, satura o de oxigênio e a retirada da oxigenoterapia. Resultados: Após dois meses de tratamento verificou- se que houve melhora nos aspectos motoradaptativo, pessoal-social e motor dessa crian a, critérios avaliados com a utiliza o da escala de Denver. O tratamento de fisioterapia respiratória influenciou na melhora da expansibilidade torácica e na redu o da secre o aspirada das vias aéreas superiores. Conclus o: A fisioterapia motora e respiratória, neste caso, trouxe melhoras importantes para o DNPM desta crian a, além da melhora ventilatória. Desta forma, sugere-se que pacientes com quadros clínicos semelhantes ao relatado poder o ser beneficiados com o tratamento referido. Objective: Narrate the case of anefric children that was submitted to respiratory and motor physiotherapy, during hospital interned period. Method: In this case study, an eleven months year old boy, anefric, was evaluated before physiotherapy treatment and two months latter of treatment. Denver’s scale was employed to evaluate neuropsicomotor development. Respiratory evaluation used vital signals, oxygen saturation and oxigenotheray withdraw. Results: After two months of physiotherapy treatment, criteria of Denver’s scale, such as motoradaptative, individual, social and motor register improvements. Respiratory physiotherapy treatment resulted in thorax expansion and reduction of secretion aspiration. Conclusion: In this case study, respiratory and motor physiotherapy brought important improvement to neuropsicomotor development of the child, as well ventilators increment. These results suggest that patients with similar clinical status could benefit with similar treatment.
A. Vimalavady et al.
International Journal of Pharmaceutical Sciences and Research , 2012,
Abstract: An ethnomedicinal plant, Hugonia mystax L., was examined for preliminary phytochemical screening and antimicrobial activity. Preliminary phytochemical screening showed the presence of various classes of secondary metabolites such as flavonoids, phenols, saponins, steroids, tannins and terpenoids. Antimicrobial activity of petroleum ether, chloroform, ethanolic and aqueous fruits extracts showed significant activity against the human pathogens such as Streptococcus pneumoniae causing brain abscesses, pneumonia and septic arthritis; Proteus vulgaris, Pseudomonas aeruginosa causing urinary tract infections and septicaemia; Salmonella typhi causing typhoid fever, Vibrio species causing diarrheal infections and the fungus Candida albicans causes urinary tract infections. The antimicrobial activity of the petroleum ether, chloroform, ethanolic and aqueous fruits extracts showed concentration-dependent activity against all the tested bacteria at various concentrations. Thus the present findings revealed the medicinal potential of H. mystax to develop a drug against various human ailments.
A. Souza et al.
International Journal of Pharmaceutical Sciences and Research , 2012,
Abstract: This work was conducted at a Libreville herbal market located in Peyrie in order to inventory plants used by people for the management of cardiovascular diseases such as hypertension and to evaluate their pharmacological effects. The method of preparation and modes of administration were also recorded. Twenty nine herbalists were interviewed using questionnaires. Twenty two plant species belonging to sixteen families and seventeen recipes were identified. The commonly used plants were Guibourtia tessmannii, Musanga ceropioiodes, Senecio gabonensis. Among them, G. tessmannii appeared to be the most used plant species. Phytochemical studies on extracts of G. tessmannii revealed the presence of alkaloids, sugars, polyphenols, sterols, tannins and saponosids. Pharmacological studies performed in the isolated aorta of rats showed a vasorelaxant effect on adrenalin- or KCl- induced contraction. G Tessmannii-induced vasorelaxation was significantly but not totally reduced by endothelium removal or by a pretreatment with L-NAME, suggesting the involvement of endothelium-dependent and -independent mechanisms. Medicinal plants and G. tessmannii in particular may represent a source of efficient antihypertensive agents.
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