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Search Results: 1 - 10 of 461805 matches for " A. Aswini "
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FPGA Implementation of Audio Enhancement Using Adaptive LMS Filters
V. Elamaran,A. Aswini,V. Niraimathi,D. Kokilavani
Journal of Artificial Intelligence , 2012,
Abstract: Digital audio has become very popular in the last two decades with the growth of multimedia systems and the World Wide Web. So, audio processing techniques such as filtering, equalization, noise suppression, compression, addition of sound effects and synthesis become necessary in the field of sound engineering. This study has presented some of the audio enhancement techniques using adaptive Least Mean Square (LMS) filters with the Field Programmable Gate Array (FPGA) Architectures which are developed using Xilinx System Generator (XSG). Verilog descriptions from XSG are synthesized to the target FPGA device-a Virtex4 xc4vsx55-12ff1148 and the resource utilization summary for the various alternate LMS architectures is obtained along with the Signal-to-Noise Ratio (SNR) calculations. Results show that Delayed LMS architectures provide a better SNR improvement at the cost of more resource utilizations.
Kabbaldurga charnockites revisited: Incipient growth or anatectic melt?  [PDF]
Samarendra Bhattacharya, Aswini K. Chaudhary
Natural Science (NS) , 2013, DOI: 10.4236/ns.2013.53055

A popular hypothesis of in situ transformation of amphibolite facies gneisses to patchy charnockites by CO2 influx from mantle was proposed primarily from the Kabbaldurga quarries in South Karnataka and subsequently reported from several south Indian localities. However, presence of abundant mafic granulite enclaves in Kabbaldurga and its neighborhood and its implications in relation to patchy charnockite genesis were not discussed. In these quarries patchy charnockites occur in various modes and associations. Some of these patches do occupy structural weak zones, such as shear bands and fold noses in the migmatitic gneisses, but many of the patchy charnockite bodies occur as branching veins transecting the gneissic foliation and hence do not account for fluid pathways. Most importantly, charnockitic leucosomes at margins of mafic granulite enclaves and charnockitic veins within some mafic granulite enclaves indicate a close genetic link between them via dehydration partial melting. This is further corroborated by trace element distribution between them. Dehydration partial melting in mafic rocks in a migmatite terrain such as Kabbaldurga, can explain all the different modes of the patchy charnockites as various stages of segregation and mobility relative to deformation. Abundant mafic granulite enclaves and field features suggesting a relatively late origin of the patchy charnockites, are compelling evidence against the notion of a transition zone. Mantle derivation age of the mafic source rocks (protoliths of mafic granulites) at Kabbaldurga at 3.08 ± 0.08 Ga with small positive ? values is virtually identical to the source of the massive charnockite of Karnataka craton at 3.08 Ga. This could imply a widespread mafic magmatism in South India around 3.0 Ga.

Prevention of bile leak after liver surgery: A fool-proof method
Pujahari Aswini
Saudi Journal of Gastroenterology , 2009,
Abstract: Background/Aim: Bile leak is not uncommon after liver surgeries. There is no adequate method described to prevent this morbid complication. Materials and Methods: At the end of the liver procedure, transcystic normal saline was injected under pressure with distal clamping. Leaking saline on the cut surface of the liver was sutured. The process was repeated till no leaking was observed. A suction drain was kept for any bile leak. Results: Open liver resection and hydatid cyst surgery cases were included. There were 24 cases, with 13 males and 11 females. The age range was from 4 to 80 years, with a mean of 48 years (SD ± 17.7). The number of leak sites that could be sutured were 0-4 (mean of 2.3 ± 0.5). None had bile leak postoperatively. Conclusion: Transcystic injection under pressure with distal clamping demonstrates the leak sites. Suturing them prevents the postoperative bile leak.
A 57-year old with abdominal lumps
Pujahari Aswini
Saudi Journal of Gastroenterology , 2007,
Problem of a rare anomalous hepatic artery during whipple procedure
Pujahari Aswini
Saudi Journal of Gastroenterology , 2010,
The genomics of oral cancer and wound healing
Aswini Y
Journal of the Indian Society of Pedodontics and Preventive Dentistry , 2009,
Abstract: Oral cancer is the most common malignancy in India, where it is epidemiologically linked to the chewing of betel quid and other carcinogens. But various point mutations were detectable in the p53 and p15 genes. Hence, this review was conducted with the aim to find out genetic risks as well as markers for oral cancers and wound healing. Tobacco-related cancers are associated with polymorphisms of the CYP1A1 and GSTM1 genes in terms of genotype frequencies and cigarette smoking dose. Expression of E6/E7 were also found in tumors, most of which were derived from the oropharynx. Presence of homozygous arginine at codon 72 renders p53 about seven times more susceptible to E6-mediated proteolytic degradation. Erythropoietin, vascular permeability factor (VPF, also known as vascular endothelial growth factor or VEGF), and PDGF has been implicated as one of the principal mitogens involved in cutaneous wound healing. Activation of NF-kB is associated with enhanced cell survival. Human papilloma virus status is a significantly favorable prognostic factor in tonsilar cancer and may be used as a marker in order to optimize the treatment of patients with this type of cancer.
The F0F1-ATP Synthase Complex Contains Novel Subunits and Is Essential for Procyclic Trypanosoma brucei
Alena Zíková,Achim Schnaufer,Rachel A. Dalley,Aswini K. Panigrahi,Kenneth D. Stuart
PLOS Pathogens , 2009, DOI: 10.1371/journal.ppat.1000436
Abstract: The mitochondrial F0F1 ATP synthase is an essential multi-subunit protein complex in the vast majority of eukaryotes but little is known about its composition and role in Trypanosoma brucei, an early diverged eukaryotic pathogen. We purified the F0F1 ATP synthase by a combination of affinity purification, immunoprecipitation and blue-native gel electrophoresis and characterized its composition and function. We identified 22 proteins of which five are related to F1 subunits, three to F0 subunits, and 14 which have no obvious homology to proteins outside the kinetoplastids. RNAi silencing of expression of the F1 α subunit or either of the two novel proteins showed that they are each essential for the viability of procyclic (insect stage) cells and are important for the structural integrity of the F0F1-ATP synthase complex. We also observed a dramatic decrease in ATP production by oxidative phosphorylation after silencing expression of each of these proteins while substrate phosphorylation was not severely affected. Our procyclic T. brucei cells were sensitive to the ATP synthase inhibitor oligomycin even in the presence of glucose contrary to earlier reports. Hence, the two novel proteins appear essential for the structural organization of the functional complex and regulation of mitochondrial energy generation in these organisms is more complicated than previously thought.
Genetics in public health: Rarely explored
Aswini Y,Varun S
Indian Journal of Human Genetics , 2010,
Abstract: The availability and the integration of genetic information into our understanding of normal and abnormal growth and development are driving important changes in health care. These changes have fostered the hope that the availability of genetic information will promote a better understanding of disease etiology and permit early, even pre-symptomatic diagnosis and preventive intervention to avoid disease onset. Hence, our aim was to review and provide the insight into the role of genetics in public health and its scope as well as barriers. The use of genetics along with their goals and essential public health functions are discussed. From the era of eugenics to the present era, this area has seen many turns in which geneticists have put through their effort to tie together the strings of both molecular genetics and public health. Though still the dark clouds of eugenics, the predictive power of genes, genetic reductionism, non-modifiable risk factors, individuals or populations, resource allocation, commercial imperative, discrimination and understanding and education are hanging above. The technological and scientific advances that have fundamentally changed our perception of human diseases fuel the expectations for this proactive health.
Intravenous magnesium sulphate as an adjuvant in acute severe asthma refractory to conventional therapy
Aswini Kumar Sahoo, SC Mohapatra
Asian Journal of Medical Sciences , 2015, DOI: 10.3126/ajms.v6i1.9609
Abstract: DOI: http://dx.doi.org/10.3126/ajms.v6i1.9609 Asian Journal of Medical Sciences Vol.6(1) 2015 134-135
Significant differences in alkaloid content of Coptis chinensis (Huanglian), from its related American species
Shreya Kamath, Matthew Skeels, Aswini Pai
Chinese Medicine , 2009, DOI: 10.1186/1749-8546-4-17
Abstract: We used microwave assisted extraction to obtain alkaloids berberine, coptisine, palmatine and hydrastine. High performance liquid chromatography (HPLC) was used to quantify each alkaloid.Hydrastis canadensis has the most berberine, whereas Coptis trifolia has the most coptisine. Hydrastine and palmatine were unique to Hydrastis canadensis and Coptis chinensis respectively.Neither Hydrastis canadensis nor Coptis trifolia contains all the alkaloids found in Coptis chinensis used in Chinese medicine. Substitutes of this Chinese species by its American relatives are not recommended.Phylogenetically related plant species exhibit phytochemical similarities [1]. For example, taxol is an anti-cancer chemical compound initially isolated from the bark of a rare tree species Taxus brevifolia (Pacific Yew tree); however, a closely related and more available species, Taxus cuspidata was later proved to be a more commercially viable source for taxol [2]. The growing popularity of Chinese herbal medicine in the United States has prompted large-scale import of raw herbs from Asia [3]. As many Chinese medicinal plants are evolutionarily related to their North American congeners, the North American species may be possible phytochemical substitutes to the Chinese medicinal herbs [4]. For example, North American ginseng (Panax quinquifolium) has become the commercial alternative to the rarer Chinese ginseng (Panax ginseng) [5]. Growing native substitutes can potentially promote local industry and reduce the ecological risks of cultivating exotic species; however, there is little information available on possible North American phytochemical substitutes to Chinese medicinal herbs.The present study investigates the alkaloid content in Coptis trifolia (American goldthread) and Hydrastis canadensis (goldenseal), two herbs found in the United States, and Coptis chinensis (Huanglian, Chinese goldthread), a Chinese medicinal herb imported from China. The three species belong to the same Ranun
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