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Search Results: 1 - 10 of 462270 matches for " A. Aparicio "
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The Star Formation History in Nearby Dwarf Galaxies: the Fossil Record in the Color-Magnitude Diagram
A. Aparicio
Physics , 1998,
Abstract: Dwarf galaxies may play a key role in the formation and evolution of bigger systems. This make a topic of major interest knowing how they form and evolve and, in particular, how their star formation histories (SFHs) have proceed since their birth. For nearby galaxies, the color-magnitude diagram (CMD) contains stars formed over all their lifetime. It is hence a fossil record of their SFHs. The analysis with synthetic CMDs provides a powerful tool to retrieve them. In this paper, I discuss the critical issues related to the computation of synthetic CMDs, present a short summary of the currently available results for the SFH extending the full life of galaxies and make a few critical considerations about the powerfulness and back-draws of the method.
Novedades en la reagrupación de los progenitores extranjeros por parte de un menor comunitario.
Lucía Aparicio Chofré
Revista Sobre la Infancia y la Adolescencia , 2011, DOI: 10.4995/reinad.2011.857
Abstract: El presente artículo analiza las últimas novedades, producidas tanto en la jurisprudencia comunitaria como en el ordenamiento jurídico espa ol, relativas al régimen jurídico aplicable a los menores nacionales comunitarios en el ejercicio del derecho a la reagrupación de sus ascendientes cuando son nacionales de un tercer Estado. En concreto el artículo se detiene en el estudio de la sentencia Zambrano del Tribunal de Justicia de la Unión Europea y en la Sentencia de la Sala de lo Contencioso- Administrativo del Tribunal Supremo de 1 de junio de 2010 y las repercusiones que las mismas han supuesto el régimen de ciudadanía de la Unión Europea y en los derechos de los menores en Espa a en el ámbito de la extranjería This paper analyses the last novelties both in the EU law and in the spanish legal system concerning the legal status of those minors that enjoy citizenship of a member state and try to exercise their rights to family reunification with their anscestor, when these ancestors are national of athird Country. Specifically, the paper focuses on the analisis of two judgments: the Zambrano Case of the Court of Justice of the European Union and the ruling of the Courtfor contentious administrative proceedings of the Spanish Suprem Court of the1 of june 2010. Finally, the paper sheds light on the consequences of thesetwo rulings in the EU nationality law and in the field of minor rights inSpanish nationality law
Mezcla de magmas en Vulcanello (Isla Vulcano, Italia)
Frazzetta, G.,Aparicio, A.
Estudios Geologicos , 2008, DOI: 10.3989/egeol.08641458
Abstract: Volcanic activity in Vulcano starts about 350 ka ago and continues up to present day with the development of thre main episodes corresponding to the calderas of Piano and La Fossa, and Vulcanello. These cover a compositional range from rhyolitic to trachybasaltic rocks. This lithological diversity is produced by different petrogenetic processes such as fractional crystallization, assimilation coupled to fractional crystallization (AFC), mixing, etc. The eruption of Vulcanello area emitted trachyandesitic materials, including shoshonites and latites. A magma-mixing process is established between trachytes and shoshonites to origine latites. Trachytes and rhyolites are produced by fractional crystallization and by ACF processes (assimilation of sedimentary rocks) from trachyandesitic magmas. La actividad volcánica de Isla Vulcano comienzó aproximadamente hace 350.000 a os y continúa hasta la actualidad con el desarrollo de tres grandes episodios correspondientes a las caldera de Piano, caldera de Fossa y a Vulcanello, que han emitido piroclastos y coladas de composiciones muy variadas, desde riolitas a traquibasaltos. Esta variedad litológica ha sido relacionada con procesos petrogenéticos tan diversos como cristalización fraccionada, asimilación simultánea con cristalización (ACF), mezcla de magmas, etc. El episodio de Vulcanello emite rocas traquiandesíticas, con composiciones shoshoníticas y latíticas. Un proceso de mezcla de magmas es reconocido entre traquitas y shoshonitas para generar latitas. Traquitas y riolitas son producidas por procesos de cristalización fraccionada simple y por ACF con asimilación de rocas sedimentarias a partir de magmas traquiandesíticos.
The spatial and age distribution of stellar populations in DDO 190
A. Aparicio,N. Tikhonov
Physics , 2000, DOI: 10.1086/301360
Abstract: The spatial distribution of stellar populations, the star formation history, and other properties of the dIrr galaxy DDO 190 have been analyzed using color--magnitude diagrams (CMDs) of about 3900 resolved stars and the Ha fluxes of HII regions. From the mean color index of the red giant branch, a mean metallicity [Fe/H]=-2.0 is obtained. The I magnitude of the TRGB has been used to estimate the distance. DDO 190 is 2.9+/-0.2 Mpc from the Milky Way, 2.1 Mpc from the M 94 group (CnV-I), 2.4 Mpc from the M 81 group and 2.9 Mpc from the barycenter of the Local Group, all indicating that it is an isolated, field galaxy. The surface-brightness distribution of the galaxy is well fitted by ellipses of ellipticity e=1-a/b=0.1 and P.A.=82deg. The radial star density distribution follows an exponential law of scale length a=43."4, corresponding to 611 pc. The Holmberg semi-major axis to mu_B=26.5 is estimated to be r^B_(26.5)=3.'0. Stellar populations of different ages in DDO 190 show strong spatial decoupling, the oldest population appearing much more extended than the youngest. Stars younger than 0.1 Gyr occupy only the central 40'' (0.55 kpc); stars younger than a few (~4) Gyr extend out to ~80'' (125 kpc), and for larger galactocentric distances only older stars seem to be present. This behavior is found in all the dIrr galaxies for which spatially extended studies have been performed and could be related with the kinematical history of the galaxy.
Effect of Ligands to Toll-Like Receptors (TLR) 3, 7 and 9 on Mice Infected with Mouse Hepatitis Virus A59  [PDF]
José L. Aparicio, Maite Duhalde Vega, Lilia A. Retegui
Open Journal of Immunology (OJI) , 2014, DOI: 10.4236/oji.2014.44015
Abstract: Mice infected with mouse hepatitis virus A59 (MHV-A59), an enveloped, positive-strand RNA Co-ronavirus, induce hepatitis, thymus involution, IgG2a-restricted hypergammaglobulinaemia, transaminase release and autoantibodies (autoAb) to liver and kidney fumarylacetoacetate hy-drolase (FAH). Since Toll-like receptors (TLR) play a central role in innate immunity, we explored the effects of TLR3, 7 and 9 stimulation on MHV mouse infection. Thus, the animals were treated with Poly (I:C), Loxoribine and CpG, the respective TLR ligands. MHV-infected mice inoculated with Poly (I:C) had significant lower levels of plasma transaminases and Ig, anti-MHV Ab, and uric acid than MHV-infected animals, whereas autoAb to kidney tissue were observed. Loxoribine only produced a slight decrease of uric acid levels and serum Ig. CpG showed deleterious effects on MHV-infected mice, since survival of animals dramatically dropped to about 10%. AutoAb to murine tissues and uric acid release were not affected, whereas transaminases and anti-MHV Ab were slightly elevated. Besides, CpG administration produced a decrease of the high levels of serum Ig induced by the virus. Therefore, results indicated that TLR3 stimulation appeared to protect the animals against the viral infection, whereas CpG aggravated its signs. Loxoribine, the TLR7 ligand, did not show major effects.
Imatinib and gastrointestinal stromal tumor (GIST): a selective targeted therapy
Fernández,A.; Aparicio,J.;
Revista Espa?ola de Enfermedades Digestivas , 2004, DOI: 10.4321/S1130-01082004001000007
Abstract: gastrointestinal stromal tumors are the most frequent mesenchymal tumors in the gastrointestinal tract. they originate from the interstitial cells of cajal and are characterized by an anomalous receptor for a growth factor with tyrosine-kinase activity (c-kit). this anomaly causes a permanent activation of the receptor and uncontrolled cell growth. these tumors show a poor response to traditional chemotherapy drugs, and are thus associated with low survival in cases of advanced disease. imatinib, a tyrosine kinase inhibitor, is an example of selective targeted oncologic therapy that induces improved survival in these patients. we discuss two cases of metastatic gastrointestinal stromal tumors with a good response to imatinib, and also review the pathophysiology and treatment-related outcome of this type of tumors. we include results from clinical phase-iii studies.
Catálogo bibliográfico de los Gasterópodos Terrestres de la Comunidad de Madrid
Aparicio, M.a T.
Graellsia , 2006,
Abstract: A total of 47 terrestrial gastropod species belonging to 18 families of the subclass Pulmonata have been collected in Comunidad de Madrid and cited in the bibliography. Three families show the largest number of cited species: Zonitidae, Higromiidae and Helicidae with six, thirteen and six species respectively. From a malacological point of view this region may be considered as a transitional area in which atlantic and mediterranean factors converge. En la Comunidad de Madrid se han recolectado y posteriormente se han citado en la bibliografía un total de 47 especies de Gasterópodos terrestres pertenecientes a 18 familias de la subclase Pulmonada. Las familias con mayor número de especies citadas son tres Zonitidae, Higromiidae y Helicidae con seis, trece y seis especies respectivamente. Desde el punto de vista malacológico esta región se puede considerar como un área de transición en la que confluyen factores atlánticos y mediterráneos.
Miguel A. Aparicio Pérez
Revista d'Estudis Autonòmics i Federals , 2011,
Abstract: In a line similar to that proposed in the State Council Report of 16 February 2006 on modifi cations to the Constitution, the Constitutional Court Ruling31/2010 has severely limited the constitutional functions of the Statutes of Autonomy while denying them any special legislative category outside thosefound in any other type of organic law. According to the jurisprudentialdoctrine of the declaration, it is clear that the Statutes of Autonomy are notadequate regulations for defining the powers and functions contained inthe powers that they attribute to the respective Autonomous Communities,therefore although they can be “described” these provisions lack regulatoryforce. Neither can the Statutes contemplate a possible development of the Autonomous State, given that the constitutional categories that belong toit and even the sub-matters over which it exercises competent functions constitutean interpretative monopoly of the Constitutional Court. This set oflimitations and inabilities mean that the Statutes of Autonomy cannot ensurean ambit of exclusive autonomous powers because, under any circumstances,the State has the power to regulate the corresponding matters usingits horizontal powers, and moreover, with the effect of supremacy. Andin the end, in relation to shared powers, the State can defi ned the basics inthe amount of detail and under the form of regulations it considers appropriate(legislative, regulatory or executive). We are therefore looking at anew attempt to declare the process of autonomy as being closed, denyingthe Statutes of possible exercising the device principle and eradicating withinthem, in appropriate feedback, their regulatory strength and their constitutional functions of origin.
Imatinib and gastrointestinal stromal tumor (GIST): a selective targeted therapy Imatinib y tumor del estroma gastrointestinal (GIST): un tratamiento selectivo frente a una diana molecular
A. Fernández,J. Aparicio
Revista Espa?ola de Enfermedades Digestivas , 2004,
Abstract: Gastrointestinal stromal tumors are the most frequent mesenchymal tumors in the gastrointestinal tract. They originate from the interstitial cells of Cajal and are characterized by an anomalous receptor for a growth factor with tyrosine-kinase activity (c-kit). This anomaly causes a permanent activation of the receptor and uncontrolled cell growth. These tumors show a poor response to traditional chemotherapy drugs, and are thus associated with low survival in cases of advanced disease. Imatinib, a tyrosine kinase inhibitor, is an example of selective targeted oncologic therapy that induces improved survival in these patients. We discuss two cases of metastatic gastrointestinal stromal tumors with a good response to imatinib, and also review the pathophysiology and treatment-related outcome of this type of tumors. We include results from clinical phase-III studies. Los tumores del estroma gastrointestinal son los tumores mesenquimales más frecuentes del tracto digestivo y se originan de las células intersticiales de Cajal. Se caracterizan por presentar un receptor para el factor de crecimiento con actividad tirosin kinasa (c-kit) anómalo que condiciona su activación permanente y un crecimiento celular incontrolado. Tienen una baja supervivencia en casos de enfermedad avanzada, con escasa respuesta a los agentes quimioterápicos tradicionales. El imatinib es un fármaco inhibidor de la tirosín kinasa y un ejemplo de terapia oncológica selectiva que condiciona un importante aumento en la supervivencia de estos pacientes. Se presentan 2 casos de enfermedad metastásica con buena respuesta a imatinib, así como una revisión sobre la fisiopatología y evolución en el tratamiento de este tipo de tumores, incluyendo resultados de estudios en fase III.
Materiales compuestos C/SiC para aplicaciones estructurales de alta temperatura. Parte II: Sistemas de protección contra la oxidación
Aparicio, M.,Durán, A.
Boletín de la Sociedad Espa?ola de Cerámica y Vidrio , 2001,
Abstract: The fact which currently excludes the use of C/SiC composites in high temperature structural applications is the high oxidation rate of carbon fibres at temperatures higher than 450oC. In this second part of the paper, a review of the different oxidation protection systems, including inhibitors, surface modification of composites, coatings and previous infiltration of the substrates, has been carried out. The addition of inhibitors reduces the oxidation rate, but only up to 850oC, while the surface modification of composites leads to thin coatings with poor thermal shock resistance. On the other hand, the external layers are the most usual method employed because allows combining different compositions and thicknesses. The multilayer coatings are especially interesting in applications with wide temperature range and thermal shocks requirements. The infiltration of substrate porosity improves slightly the oxidation resistance of C/SiC composites reducing the oxygen accessibility to carbon fibres. However, the infiltration complements very well the oxidation protection performance of a coating system at low temperature, since these normally present open cracks due to mismatch between coating and substrate thermal expansion coefficients. La utilización de los materiales compuestos C/SiC en aplicaciones estructurales a alta temperatura está limitada por la elevada velocidad de oxidación de la fibra de carbono a temperaturas superiores de 450oC. En esta segunda parte del trabajo se realiza una revisión de las posibilidades de protección contra la oxidación de estos materiales, incluyendo inhibidores, modificación superficial del material compuesto, recubrimientos e infiltración previa del sustrato. La eficacia de los inhibidores de la reacción de oxidación esta restringida a temperaturas de hasta 850oC, mientras que la modificación superficial del material compuesto da lugar a capas delgadas y poco resistentes a los ciclos térmicos. En cambio, los recubrimientos son el método más empleado porque permiten combinar composiciones y espesores de capa muy variados. La estructura multicapa es especialmente interesante en el caso de aplicaciones con intervalos de temperatura de trabajo amplios y cuando el material va a estar sometido a choques térmicos. La infiltración de la porosidad del sustrato sólo mejora ligeramente la resistencia a la oxidación del material compuesto C/SiC al reducir los caminos de acceso del oxígeno a las fibras de carbono. Sin embargo, la infiltración complementa en gran medida las propiedades antioxidantes de los recubrimientos en el inter
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