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Search Results: 1 - 10 of 29 matches for " ; Faruqi "
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Synthesis, Spectroscopic, and in Vitro Cytotoxic Studies of Fatty Acid Analogues of 2, 6-Diisopropylphenol  [PDF]
Ali Mohammad, Fauzia B. Faruqi, Jamal Mustafa
Journal of Cancer Therapy (JCT) , 2010, DOI: 10.4236/jct.2010.13020
Abstract: This paper represents the synthesis, spectral analysis and in-vitro cytotoxic studies of some novel fatty acid anti-cancer conjugates of 2, 6-diisopropylphenol (propofol). Propofol is a potent intravenous hypnotic agent which is widely used for the induction and maintenance of anesthesia and for sedation in the intensive care unit. Propofol also possess anti-cancer properties in addition to its sedative effects. Cytotoxicity of all the synthesized compounds was examined against human HeLa cancer cell lines. The anti-cancer screening of these novel drug candidates suggest that all of them reported here may be useful for the treatment of cancer as all of them exhibited significant anticancer activity against human HeLa cancer cell lines. The results indicate that these novel drug candidates might represent a new class of anticancer agents.
Simulation analysis of passive solar structures using heat transfer equations
M. Faruqi,P. Ghavami
Journal of Engineering and Applied Sciences , 2010,
Abstract: Passive solar design is an economical way of using solar energy in buildings. The thermal behavior of the buildings within its environment over a period of time can easily be predicted using accurate and simple analytical tools. This provides designers the information necessary to satisfy the occupant’s needs, reduce peak cooling/heating power demands, reduce the size of air conditioning/heating equipment, and the period for which it is required. There by, increasing the possibility of a successful design. The main goal of this study is to present modeling of passive solar structures using heat transfer equations. The simulation model results correlated well with the experimental data.
Morphometric Analysis of Infraorbital Foramen in Human Foetuses
Farah,Ghaus; Faruqi,N. A.;
International Journal of Morphology , 2007, DOI: 10.4067/S0717-95022007000200009
Abstract: a detailed knowledge of the anatomic morphometry of infraorbital groove, canal and foramen was necessary for a surgeon while performing maxillofacial surgery and regional block anaesthesia. modern surgical procedures as well as anaesthesia require more precise understanding of the surrounding anatomy. the aim of the study was to establish morphometrically the infraorbital foramen size and location in human foetuses, the area where this information was scanty. sixty maxillae were dissected out from thirty human foetuses. the latter were divided into five groups on the basis of age i.e. groups i(<17 weeks iul),ii (17-20 weeks iul), iii (21-25 weeks iul),iv (26-30 weeks iul) and v (>30 weeks iul). four parameters including transverse diameter and vertical diameter of infraorbital foramen and its distances from the infraorbital margin and nasal notch, were considered. foramen was nearly circular in group i foetuses (transverse as well as vertical diameter being 0.6 mm approximately) but in subsequent groups,the foramen is transversely oval due to faster increase in transverse diameter (1.93 mm in group v whereas the vertical diameter in group v remained 1.21 mm only). downward displacement was found to be relatively more than the lateral displacement. third group showed maximum increase in all the four parameters. some association between diameter of infraorbital foramen and foetal age was established on the basis of correlation coefficient analysis
Bilateral Variations and Sexual Dimorphism in Morphometric Parameters of Infraorbital Groove, Canal and Foramen in Human Foetuses
Ghaus,Farah; Faruqi,N. A;
International Journal of Morphology , 2009, DOI: 10.4067/S0717-95022009000200027
Abstract: foetal anatomy seems to be highly promising developing speciality in the recent past. maxilla is the key to facial skeleton. its anatomy in general and bilateral variations along with sexual dimorphism in particular are of great surgical and forensic importance.thirty two maxillae of sixteen human foetuses (21 wks to 34 wks) were considered to measure lengths of infraorbital groove and canal, widths of ends of infraorbital groove, diameters of infraorbital foramen and the distances of latter from infraorbital margin and nasal notch. groups i (21-25 wks) and ii (26-30 wks) foetuses were crucial for bilateral variations for most of the parameters. distance between infraorbital foramen and nasal notch showed variations on two sides in maximum foetal groups. infraorbital canal was found to be larger in groups ii and iii foetuses in females. width of the posterior end of infraorbital groove was less in group i, equal in group ii and more in group iii in males. sexual dimorphism was noticed in all the groups for the distance of infraorbital foramen from infraorbital margin. distance of infraorbital foramen from nasal notch did not show sexual dimorphism in most of the groups except group i where value was more in males. rule of generalized phenomenon of larger skeleton in male was not applicable in most of the groups.
Morphometric Analysis of Infraorbital Foramen and Infraorbital Canal in Human Feotuses
Farah,Ghaus; Faruqi,N. A;
International Journal of Morphology , 2008, DOI: 10.4067/S0717-95022008000200007
Abstract: literature regarding analysis of infraorbital foramen and canal exists in adult but it is scanty in foetuses.morphometric measurements were performed in sixty maxillae dissected out from thirty human foetuses.the latter were divided into five groups on the basis of age i.e. groups i(<17 weeks iul),ii (17-20 weeks iul), iii (21-25 weeks iul),iv (26-30 weeks iul) and v (>30 weeks iul).four parameters considered were length of infraorbital foramen and canal and width of anterior and posterior ends of infraorbital foramen. range of measurements between the smallest foetal group to largest foetal group for length of infraorbital foramen and canal and width at the anterior and posterior ends of infraorbital foramen were 4.01mm to 6.00 mm,0.67 mm to 2.60 mm,0.64 mm to 1.65 mm and 1.39 mm to 3.01 mm, respectively.the shape of the infraorbital foramen is maintained in most of the groups.correlation coefficient analysis between measurements of lengths and aging foetuses is indicative of variable osteoblastic and osteoclastic activities.enhanced osteoblastic activity seems to be an important phenomenon in postnatal life.
Morphometric Analysis of the Sockets for the Upper Temporary Molar Teeth in Human Foetuses
Farah,Ghaus; Faruqi,N. A;
International Journal of Morphology , 2010, DOI: 10.4067/S0717-95022010000300044
Abstract: foetal therapy has made foetal anatomy a promising field. maxilla had been the core research attraction of many scientists. alveolar arches, specially the maxillary one had been consistently the focus of attention for research workers due to its importance in dentistry. twenty nine human foetuses were grouped into i (<24 weeks of iul), ii (25-30 weeks of iul) and iii (>30 weeks of iul). maxillae were dissected out and sockets were carefully cleaned. sockets for the temporary molars, which also hold permanent premolars were measured with the help of vernier callipers. three parameters, i.e. maximum mesiodistal diameter,maximum transverse diameter and maximum depth were considered. readings were analysed statistically by using student's 't' test. growth was maximum in group ii for the mesiodistal diameter of the socket for 1st temporary molar but significant bilateral variation or sexual dimorphism was not found. a very high rate of growth (+63%) was noticed in group ii foetuses. contrary to mesiodistal values, transverse diameter showed significant higher values on left side in group ii foetuses. similarly in late foetuses of group iii, values were significantly more in males than those in females. it might be reflecting the higher measurements in general in male adult skeleton compared to females. the increase in the depth was significantly higher in the last two groups but the rate was again more in group ii (57%) than in group iii (29%). although no bilateral variations were noticed, the value was found to be higher in male than female in last foetal group. the values increased with great rate in both group ii and iii foetuses for the mesiodistal diameter of the socket for 2nd temporary molar. an unexpected increase in the mesiodistal readings of female socket was observed in group ii. the values of transverse diameter showed a consistent increase i.e. a significant increase in group ii and iii foetuses, a pattern observed in mesiodistal diameters also. values of
Morphometric Analysis of Developing Maxillary Sinuses in Human Foetuses
Farah,Ghaus; Nafis,Ahmad Faruqi;
International Journal of Morphology , 2006, DOI: 10.4067/S0717-95022006000400002
Abstract: the development of the paranasal sinuses, in human race and in many mammals remained as much an enigma as it did nearly two millennia ago. morphometric analysis of maxillary sinuses in human foetuses are not fully documented and also their morphological studies in indian population are non-existent. so the present study was conducted to determine the different diameters, the pattern of growth, sexual dimorphism and bilateral variations in maxillary sinuses. 37 human foetuses of different age groups (16 - 34 wks of iul) were divided into five groups on the basis of age. maxillary sinuses were dissected out from the nasal aspects of maxillae and their various diameters were measured with the help of vernier callipers. the percent growth of ap diameter was +48% in 17-20 wks (p <0.001), of vertical diameter was +60% in 17-20 wks (p <0.001) and of transverse diameter was + 47% in 17-20 wks (p <0.001). out of 3,anteroposterior diameters were maximum throughout foetal life. ap diameters of both sides of a foetus had significant variation (p <0.005) in <17 wks. ap diameters were invariably more in males but significant variation (p <0.001) was found only in 26-36 wks while significant variation (p <0.02) was observed in transverse diameters in males of 21-25 wks. anteroposterior dimensions showed faster growth while other diameters were in pace with the head circumference. it was concluded that: 1) different diameters of maxillary sinus have spurt of growth in different periods of iul. 2) values of anteroposterior diameter remain higher, right from the beginning to the end of intra-uterine life. 3) maxillary sinuses remain relatively larger in males throughout life
Morphometric Analysis of Developing Maxillary Sinuses in Human Foetuses Análisis Morfométrico del Desarrollo de los Senos Maxilares en Fetos Humanos
Ghaus Farah,Ahmad Faruqi Nafis
International Journal of Morphology , 2006,
Abstract: The development of the paranasal sinuses, in human race and in many mammals remained as much an enigma as it did nearly two millennia ago. Morphometric analysis of maxillary sinuses in human foetuses are not fully documented and also their morphological studies in Indian population are non-existent. So the present study was conducted to determine the different diameters, the pattern of growth, sexual dimorphism and bilateral variations in maxillary sinuses. 37 human foetuses of different age groups (16 - 34 wks of IUL) were divided into five groups on the basis of age. Maxillary sinuses were dissected out from the nasal aspects of maxillae and their various diameters were measured with the help of Vernier callipers. The percent growth of AP diameter was +48% in 17-20 wks (p <0.001), of vertical diameter was +60% in 17-20 wks (p <0.001) and of transverse diameter was + 47% in 17-20 wks (p <0.001). Out of 3,anteroposterior diameters were maximum throughout foetal life. AP diameters of both sides of a foetus had significant variation (p <0.005) in <17 wks. AP diameters were invariably more in males but significant variation (p <0.001) was found only in 26-36 wks while significant variation (p <0.02) was observed in transverse diameters in males of 21-25 wks. Anteroposterior dimensions showed faster growth while other diameters were in pace with the head circumference. It was concluded that: 1) Different diameters of maxillary sinus have spurt of growth in different periods of IUL. 2) Values of anteroposterior diameter remain higher, right from the beginning to the end of intra-uterine life. 3) Maxillary sinuses remain relatively larger in males throughout life El desarrollo de los senos paranasales en humanos y en muchos mamíferos ha permanecido como un enigma hace ya varios milenios. Análisis morfométricos de los senos maxilares en fetos humanos no han sido suficientemente documentados y en la India son inexistentes. El presente estudio fue llevado a cabo para determinar los diferentes diámetros, el padrón de crecimiento, el dimorfismo sexual y las variaciones bilaterales en los senos maxilares de 37 fetos humanos de diferentes edades (16-34 semanas de vida intrauterina), los cuales fueron divididos en 5 grupos etarios. Los senos maxilares fueron disecados por la parte nasal del maxilar y los diversos diámetros fueron medidos con la ayuda de un caliper. El crecimiento porcentual del diámetro AP fue +48% en los fetos de 17-20 semanas (p <0.001), el diámetro vertical fue de +60% (p <0.001).Los diámetros AP de ambos lados de un feto tuvieron una variación si
Morphometric Analysis of Infraorbital Foramen and Infraorbital Canal in Human Feotuses Análisis Morfométrico del Foramen Infraorbitario y Canal Infraorbitario en Fetos Humanos
Ghaus Farah,N. A Faruqi
International Journal of Morphology , 2008,
Abstract: Literature regarding analysis of infraorbital foramen and canal exists in adult but it is scanty in foetuses.Morphometric measurements were performed in sixty maxillae dissected out from thirty human foetuses.The latter were divided into five groups on the basis of age i.e. groups I(<17 weeks IUL),II (17-20 weeks IUL), III (21-25 weeks IUL),IV (26-30 weeks IUL) and V (>30 weeks IUL).Four parameters considered were length of infraorbital foramen and canal and width of anterior and posterior ends of infraorbital foramen. Range of measurements between the smallest foetal group to largest foetal group for length of infraorbital foramen and canal and width at the anterior and posterior ends of infraorbital foramen were 4.01mm to 6.00 mm,0.67 mm to 2.60 mm,0.64 mm to 1.65 mm and 1.39 mm to 3.01 mm, respectively.The shape of the infraorbital foramen is maintained in most of the groups.Correlation coefficient analysis between measurements of lengths and aging foetuses is indicative of variable osteoblastic and osteoclastic activities.Enhanced osteoblastic activity seems to be an important phenomenon in postnatal life. Existe literatura en relación con el análisis de foramen y canal infraorbitarios en adultos pero es escasa en fetos. Se realizaron mediciones morfométricas en 60 maxilares disecados de 30 fetos humanos. Los fetos fueron divididos en cinco grupos en función de la edad, es decir los grupos I (<17 semana VIU), II (17-20 semanas VIU), III (21-25 semanas VIU), IV (26-30 semanas VIU) y V (> 30 semanas VIU). Fueron considerados cuatro parámetros : longitudes del foramen y canal infraorbitario y anchos anterior y posterior de los extremos del foramen infraorbitario. El rango de las mediciones entre el grupo de fetos más peque o al grupo más grande tanto de las longitudes del foramen y canal infraorbitario como los anchos de los extremos en la parte anterior y posterior del foramen infraorbitario fueron: 4.01mm a 6.00 mm, 0.67 mm a 2.60 mm, 0.64 mm a 1.65 mm y 1.39 mm a 3.01 mm, respectivamente. La forma del foramen infraorbitario se mantuvo en la mayoría de los grupos. El análisis del coeficiente de correlación entre las mediciones de longitudes y edades de los fetos, es indicativo de las variables de actividades osteoblástica y osteoclástica. El aumento de la actividad osteoblástica parece ser un fenómeno importante en la vida postnatal.
Morphometric Analysis of Infraorbital Foramen in Human Foetuses Análisis Morfométrico del Foramen Infraorbital en Fetos Humanos
Ghaus Farah,N. A. Faruqi
International Journal of Morphology , 2007,
Abstract: A detailed knowledge of the anatomic morphometry of infraorbital groove, canal and foramen was necessary for a surgeon while performing maxillofacial surgery and regional block anaesthesia. Modern surgical procedures as well as anaesthesia require more precise understanding of the surrounding anatomy. The aim of the study was to establish morphometrically the infraorbital foramen size and location in human foetuses, the area where this information was scanty. Sixty maxillae were dissected out from thirty human foetuses. The latter were divided into five groups on the basis of age i.e. groups I(<17 weeks IUL),II (17-20 weeks IUL), III (21-25 weeks IUL),IV (26-30 weeks IUL) and V (>30 weeks IUL). Four parameters including transverse diameter and vertical diameter of infraorbital foramen and its distances from the infraorbital margin and nasal notch, were considered. Foramen was nearly circular in group I foetuses (transverse as well as vertical diameter being 0.6 mm approximately) but in subsequent groups,the foramen is transversely oval due to faster increase in transverse diameter (1.93 mm in group V whereas the vertical diameter in group V remained 1.21 mm only). Downward displacement was found to be relatively more than the lateral displacement. Third group showed maximum increase in all the four parameters. Some association between diameter of infraorbital foramen and foetal age was established on the basis of correlation coefficient analysis Conocer en detalle la anatomía y morfometría de la incisura, canal y foramen infraorbitales, es importante para los crujanos maxilofaciales en el bloqueo anestésico regional. Modernos procedimientos quirúrgicos, como también anestésicos, requieren un conocimiento más preciso de la anatomía de esa zona. El objetivo de este estudio fue establecer mofológicamente el tama o y la localization de estas estructuras, en fetos humanos, área en la cual existe insuficiente información. Fueron disecados 60 maxilares, de 30 fetos humanos. Los fetos fueron divididos en cinco grupos basados en la edad: Grupo I (<17semanas VIU), II (17-20 semanas VIU), III (21-25 semanas VIU), IV (26-30 semanas VIU) y V (>30 semnaas VIU). Fueron considerados cuatro parámetros, incluyendo diámetros transverso y vertical del foramen infraorbital y sus distancia entre el margen infraorbital y la incisura nasal. El foramen infraorbital era aproximadamente circular en el Grupo I de fetos (tanto el diámetro transverso como el diámetro vertical medían 0,6 mm, aproximadamente) pero en los grupos subsecuentes, el foramen infraorbital era oval transversa
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