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Search Results: 1 - 10 of 14278 matches for " *Meenakshi Singh "
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Selective Recognition and Detection of L-Aspartic Acid by Molecularly Imprinted Polymer in Aqueous Solution  [PDF]
Nazia Tarannum, Meenakshi Singh
American Journal of Analytical Chemistry (AJAC) , 2011, DOI: 10.4236/ajac.2011.28105
Abstract: Molecularly imprinted polymers selective for L-aspartic acid (LAA) have been prepared using the carboxy-betaine polymer bearing zwitterionic centres along the backbone. LAA is well known to promote good me-tabolism, treat fatigue and depression along with its significance in accurate age estimation in the field of forensic science and is an important constituent of ‘aspartame’, the low calorie sweetener. In order to study the intermolecular interactions in the prepolymerization mixture between the monomer and the template (LAA)/non-template (DAA), a computational approach was developed. It was based on the binding energy of the complex between the template and functional monomer. The results demonstrate that electrostatic in-teractions primarily guide the imprinting protocol. The MIP was able to selectively and specifically take up LAA from aqueous solution, human blood serum and certain pharmaceutical samples quantitatively. Hence, a facile, specific and selective technique to detect the amino acid, LAA in the presence of various interfer-rants, in different kinds of matrices is presented.
Imperfection of Domain Knowledge and Its Formalization in Context of Design of Robust Software Systems  [PDF]
Meenakshi Sridhar, Naseeb Singh Gill
Journal of Software Engineering and Applications (JSEA) , 2015, DOI: 10.4236/jsea.2015.89047
Abstract: In this paper, it is emphasized that taking into consideration of imperfection of knowledge, of the team of the designers/developers, about the problem domains and environments is essential in order to develop robust software metrics and systems. In this respect, first various possible types of imperfections in knowledge are discussed and then various available formal/mathematical models for representing and handling these imperfections are discussed. The discussion of knowledge classification & representation is from computational perspective and that also within the context of software development enterprise, and not necessarily from organizational management, from library & information science, or from psychological perspectives.
Surface Photografting of Novel Sulfobetaine Copolymers on Silica  [PDF]
Abhishek Kumar, Nazia Tarannum, Meenakshi Singh
Materials Sciences and Applications (MSA) , 2012, DOI: 10.4236/msa.2012.37066
Abstract: A couple of novel sulfobetaine copolymer is developed via Michael-type addition reaction. The comonomers, diamines and maleimide react via Michael reaction through UV irradiation using AIBN as photoinitiator producing polyamine chain. Further, sulfobetaine copolymers were obtained on treatment of the polyamine with sulfopropylating agent, 1,3-propane sultone. These novel sulfobetaine polymers were grafted on silica surface to produce responsive biocompatible surface. This easy straightforward, catalyst free facile protocol for synthesis of polymer grafted surface is useful for developing biomedical devices. Additionally, both the copolymers show fluorescence characteristics.
Isolation of Campylobacters from Intestinal Tract of Poultry in Northern Region of India  [PDF]
Chetana Vaishnavi, Meenakshi Singh, Prashant Kapoor
Advances in Microbiology (AiM) , 2015, DOI: 10.4236/aim.2015.512084
Abstract: Campylobacter is one of the most common food-borne bacterial enteropathogens. We planned to investigate the prevalence and antibiotic resistogram of Campylobacter in poultry in and around Chandigarh. Poultry samples (n = 127) were obtained from slaughter houses/retail outlets and cultured microaerophilically on Campylobacter media. The isolates were identified phenotypically and by molecular investigation. Identification of specific genes to look for resistance to nalidixic acid, ciprofloxacin, tetracyclin and streptomycin was also done. Campylobacter was isolated from 57/127 (44.9%) of the samples. The most frequent serotypes identified were B: 2, S: 27, Z5: 52 and Z7: 57. All culture isolates (100%) were reconfirmed as Campylobacter by 16S rRNA polymerase chain reaction. Molecular identification of isolates revealed the presence of C. jejuni in 45 (79.0%), C. coli in 1 (1.8%) and co-infection of C. coli and C. jejuni in 11 (19.3%). No C. lari and C. upsaliensis
Low Prevalence of Campylobacteriosis in the Northern Region of India  [PDF]
Chetana Vaishnavi, Meenakshi Singh, Jarnail Singh Thakur, Babu Ram Thapa
Advances in Microbiology (AiM) , 2015, DOI: 10.4236/aim.2015.53015
Abstract: Campylobacter is one of the most common bacterial enteropathogens of food borne origin in industrialized countries with C. jejuni being the most common species followed by C. coli. The prevalence of Campylobacters in and around Chandigarh, India was studied by phenotypic and genotypic methods. Fecal samples from 1145 diarrheal patients and 102 healthy subjects from hospital and community were cultured on Campylobacter media and identified by Gram stain, biochemical investigations and serotyping. Molecular identification of Campylobacter isolates was done using specific primers to unique regions of 16S rRNA, Campylobacter jejuni (hipO), Campylobacter coli (aspK), Campylobacter lari (glyA) and Campylobacter upsaliensis (lpxA) genes. Identification of specific genes to look for resistance to nalidixic acid, ciprofloxacin, tetracyclin and streptomycin was also done. Campylobacters were isolated from 2.6% of patients with diarrhea. Campylobacteriosis was more prevalent in children ≤5 years old and during summer season. The most frequent serotypes were S:27, B:2, Z5:52 and V:32. All the Campylobacters isolated by culture were confirmed genotypically by identification of 16S rRNA, hipO and aspK genes. Of the 30 isolates, 27 were C. jejuni and 3 were C. coli. No C. lari or C. upsaliensis were detected. Antibiotic resistance was 40% for nalidixic acid, 23.3% for ciprofloxacin, 50% for tetracyclin and 20% for streptomycin. Campylobacter prevalence is low in the region with C. jejuni being the most common species. A high degree of resistance was found for nalidixic acid and tetracyclin but moderate for ciprofloxacin and streptomycin.
Monitoring Water Level in Agriculture Using Sensor Networks
Iqbal Singh,Meenakshi Bansal
International Journal of Soft Computing & Engineering , 2011,
Abstract: Recent advances in communications technology andwireless sensor networks made new trends to emerge inagriculture sector. One such new trend is Precision Agriculture.In this paper we are giving brief outline of using Wireless SensorNetworks (WSN) in Monitoring water level in the farm area forPrecision Agriculture. This algorithm offers a maximumopportunity of delivery of water level informationpackets/signals to base station as it also computes a threshold aswell as does calculates values based on transmission range. Thisover all computational mechanism helps us to build a robustmechanism for delivery of information to base station thus,reducing the packet loss. Our algorithm which picks up theinformation for water level can be further optimized by usingoptimization algorithms, which lead to smoothening of packetdelivery ratio, thereby increasing the packet delivery ratio bychoosing the right cost path with the help of optimizationtechniques like genetic algorithm, neural networks.
Conductivity Studies in Proton Irradiated AgI-Ag2O-V2O5-TeO2 Super-Ionic Glass System  [PDF]
Poonam Sharma, Dinesh Kumar Kanchan, Meenakshi Pant, Karan Pal Singh
Materials Sciences and Applications (MSA) , 2010, DOI: 10.4236/msa.2010.12011
Abstract: The electrical properties of proton ion beam irradiated glass samples are carried out by impedance spectroscopy in the frequency range from 10 Hz to 32 MHz. The ion beam of energy 3 MeV and fluence of of 1014 particles cm-2 was chosen for irradiation. The conductivity of the super ionic glass samples increases after irradiation and other electrical parameters like dielectric constant, dielectric loss and modulus of the proton irradiated glass samples as a function of glass composition and temperature are observed to change. The dielectric constant and the dielectric losses are increased after irradiation and the modulus parameters confirm the non-Debye nature for irradiated samples also.
Surveillance for Antibiotic Resistance in Clostridium difficile Strains Isolated from Patients in a Tertiary Care Center  [PDF]
Meenakshi Singh, Chetana Vaishnavi, Safrun Mahmood, Rakesh Kochhar
Advances in Microbiology (AiM) , 2015, DOI: 10.4236/aim.2015.55034
Abstract: Clostridium difficile is the major etiological agent of nosocomial diarrhea primarily precipitated by antimicrobial therapy. We prospectively investigated the antibiogram profile of C. difficile strains isolated from patients reporting to a tertiary care hospital in North India. Fecal samples obtained from 1110 suspected cases of C. difficile infection were cultured for isolation of C. difficile. Colonies suspected as those of C. difficile were identified by phenotypic and molecular methods. Antimicrobial susceptibility of C. difficile isolates for different classes of antibiotics was determined using the Epsilon test for vancomycin, metronidazole, clindamycin and ciprofloxacin. The fecal samples cultured for C. difficile belonged to 709 (63.9%) males and 401 (36.1%) females. The mean age of the patients was 38.7 years. C. difficile was cultured from 174 (15.7%) of the total samples. Antibiotic resistance was largely observed towards clindamycin (57.5%) and ciprofloxacin (38.5%) but was significantly low towards metronidazole (1.72%) and nil (0%) towards vancomycin. C. difficile isolates had a high degree of resistance towards clindamycin and ciprofloxacin with low level of resistance to metronidazole and none towards vancomycin. Antibiogram surveillance of C. difficile will help for clinical practice and add to the epidemiological data of the organisms.
Performance Analysis of DSDV Protocol Using NS-2
Meenakshi,Dr.Paramjit Singh
International Journal of Computer Science and Management Studies , 2012,
Abstract: The instantly created network does not have any base infrastructure as used in the conventional networks, but it is compatible with the conventional networks. DSDV is a modification of the conventional Bellman- Ford routing algorithm. It addresses the drawbacks related to the poor looping properties of RIP in the face of broken links. The modification adapted in DSDV makes it a more suitable routing protocol for ad hoc networks. This paper reviews the DSDV protocol under different mobility models. The paper is organized under different sections. Section 1 includes the introduction of the MANETs, Section 2 describes the mobility models under consideration, Section 3 is about the overview of DSDV protocol and last sectioni.e., Section 4 is about the simulation environment. Section 5 presents the simulation model and the results.
Kumari Nutan Sinha,Meenakshi Singh
Bioscience Discovery , 2013,
Abstract: Bauhinia blakeana Dunn. is a hybrid belonging to Family Caesalpiniaceae, tribe Cercideae. Studies of Morphological characters, cytological characters and phytochemical screening of leaf aterials of B. blakeana and it sparental species have been carried out. The putative parental species shared many morphological similarities with B. blakeana. Average chiasmata per bivalent were intermediate between B. purpurea and B. variegata. Two common flavonols viz. kaempferol, quercetin (Quercetin-3-rhamnosides) were detected in all the species while isorhamnetin was detected in B. blakeana and B. purpurea. Apigenin was present in all the species. Flavonols (spots 7, 18) were common in B. blakeana and B. purpurea and (spot 5) in B. blakeana and B. variegate while (spot 10) was common in B. purpurea and B. variegata. Results of the present study showed complementation of their putative parental species.
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