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Search Results: 1 - 10 of 69 matches for " ?pela Ulaga "
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The brachiopod Lingula from the Middle Miocene – Badenian beds of Slovenia
Vasja Miku?,Milo? Bartol,pela Ulaga
Geologija , 2012,
Abstract: The article discusses the first find of an inarticulate brachiopod in Slovenia. The fossil was discovered in Miocenebeds in Badenian sandy and marly limestones outcropping in the Plesko quarry near Trbovlje. It belongs to thespecies Lingula dregeri Andreae, 1893.
Patient, doctor, disease, and informed consent
Riccardo Pela
Multidisciplinary Respiratory Medicine , 2011, DOI: 10.1186/2049-6958-6-1-8
Abstract: Taking into account the prognosis of locally advanced or metastatic lung cancer, the utility of chemotherapy is discussed more often with the patient's relatives than with the patient him/herself. But survival and quality of life (QoL) are significantly better in patients treated with chemotherapy than in those who receive the best supportive care but not chemotherapy.In this respect it has been demonstrated that the patient is more agreeable to chemotherapy than are the relatives and even the doctor, if the expected results are in terms of survival or quality of life [1]:? 57% of patients opt for chemotherapy if the oneyear-survival is at least 10%? 68% of patients opt for chemotherapy if the QoL is ameliorated? the majority of patients opt for chemotherapy if a median survival of at least 4.5 months is expected.So, a real informed consent is of paramount importance in order to obtain the patient's cooperation for the therapeutic plan. The informed participation of the patient - in the sense of understanding the disease, its therapy and the interaction between the two - is necessary for the patient to be able to deal with a critical period of his/her life. This task is even more important in the case of enrolment in clinical trials.The study by Zaric et al. in this issue [2] carried out a survey on the perception of lung cancer patients undergoing experimental treatments. The authors argue that "the patients participating in clinical trials contribute not only to their own and future patients' treatment benefits, but also to the benefits of medicine and the science itself" and they ask the question: "physicians are aware of this fact, but are the patients aware of the same fact, too?".In this respect, 59 patients with advanced lung cancer, previously treated and enrolled in a clinical therapeutic trial, filled in a questionnaire with 20 items. The patients were asked about their knowledge of their own disease (type, stage) and the kind of therapy (previously and cu
Arhitektura in komunikacija
pela Hudnik
Urbani Izziv , 2003,
Abstract: V lanku je predstavljen vpliv tehnologije, znanosti in kapitalskih strategij na spremembe tradicionalnih oblik in definicij prostora, arhitekture in telesa. Spoznava nas z novimi procesi mi ljenja in bivanja, ki se stalno preoblikujejo v novih dinami nih asovnih in prostorskih kontekstih. Prostor postaja informacijski filter, komunikacijska mre a. S prerezom treh pokrajin: pokrajine megastruktur, nomadske pokrajine in psihedeli ne pokrajine teorija prispeva k razumevanju razvoja medijev in vesoljske tehnologije, informacijske tehnologije in elektronskega jezika. Ponuja oblikovanje razli nih megastruktur, medijskih povr in in ovojev sodobne informacijske dru be: antropolo ki modul, hipertelesa in infratelesa, bioelekronska telesa in telesa populacijske genetike. Predstavlja arhitekturo komunikacije.
Architecture and communication
pela Hudnik
Urbani Izziv , 2003,
Abstract: The article presents effects of technology, science and capital strategies on changes in traditional forms and definitions of space, architecture and bodies. It confronts us with new processes of thinking and living that are constantly being transformed into new dynamic time and spatial contexts. Space is becoming the information filter, communication network. A cross-section of three landscapes: landscape of megastructures, nomadic landscapes and psychedelic landscapes, theory contributes to understanding of media and space-age technology, information technology and electronical language. It offers designs of various megastructures, media surfaces and envelopes of contemporary information society: the anthropological module, hyper- and infra-bodies, bio-electronical bodies and population genetics bodies. It presents the architecture of communication.
La subjectivité littéraire dans _La cité des dames_
pela ?akelj
Voix Plurielles , 2011,
Abstract: L’expression du féminisme dans la littérature médiévale est liée à l’expression de la subjectivité. En refusant d’être une femme incompétente ou un objet sexuel Christine de Pizan décide de répondre à la misogynie médiévale à travers ses oeuvres littéraires, surtout dans la Cité des Dames, ville imaginaire construite selon le go t des femmes.
On the image of a noncommutative polynomial
pela ?penko
Mathematics , 2012,
Abstract: Let $F$ be an algebraically closed field of characteristic zero. We consider the question which subsets of $M_n(F)$ can be images of noncommutative polynomials. We prove that a noncommutative polynomial $f$ has only finitely many similarity orbits modulo nonzero scalar multiplication in its image if and only if $f$ is power-central. The union of the zero matrix and a standard open set closed under conjugation by $GL_n(F)$ and nonzero scalar multiplication is shown to be the image of a noncommutative polynomial. We investigate the density of the images with respect to the Zariski topology. We also answer Lvov's conjecture for multilinear Lie polynomials of degree at most 4 affirmatively.
Active Protein Aggregates Produced in Escherichia coli
pela Peternel,Radovan Komel
International Journal of Molecular Sciences , 2011, DOI: 10.3390/ijms12118275
Abstract: Since recombinant proteins are widely used in industry and in research, the need for their low-cost production is increasing. Escherichia coli is one of the best known and most often used host organisms for economical protein production. However, upon over-expression, protein aggregates called inclusion bodies (IBs) are often formed. Until recently IBs formation represented a bottleneck in protein production as they were considered as deposits of inactive proteins. However, recent studies show that by choosing the appropriate host strain and designing an optimal production process, IBs composed from properly folded and biologically active recombinant proteins can be prepared. Such active protein particles can be further used for the isolation of pure proteins or as whole active protein particles in various biomedical and other applications. Therefore interest in understanding the mechanisms of their formation as well as their properties is?increasing.
Isolation of biologically active nanomaterial (inclusion bodies) from bacterial cells
pela Peternel, Radovan Komel
Microbial Cell Factories , 2010, DOI: 10.1186/1475-2859-9-66
Abstract: To prepare large quantities of a high quality product, the whole bioprocess has to be optimised. This includes not only the cultivation of the bacterial culture, but also the isolation step itself, which can be of critical importance for the production process.To determine the most appropriate method for the isolation of biologically active nanoparticles, three methods for bacterial cell disruption were analyzed.In this study, enzymatic lysis and two mechanical methods, high-pressure homogenization and sonication, were compared.During enzymatic lysis the enzyme lysozyme was found to attach to the surface of IBs, and it could not be removed by simple washing. As this represents an additional impurity in the engineered nanoparticles, we concluded that enzymatic lysis is not the most suitable method for IBs isolation.During sonication proteins are released (lost) from the surface of IBs and thus the surface of IBs appears more porous when compared to the other two methods. We also found that the acoustic output power needed to isolate the IBs from bacterial cells actually damages proteins structures, thereby causing a reduction in biological activity.High-pressure homogenization also caused some damage to IBs, however the protein loss from the IBs was negligible. Furthermore, homogenization had no side-effects on protein biological activity.The study shows that among the three methods tested, homogenization is the most appropriate method for the isolation of active nanoparticles from bacterial cells.In recent years, the rapid expansion of biotechnology has lead to the production of a wide spectrum of recombinant proteins. To this end, a range of host organisms, from bacteria to mammalian cell-culture systems are being used. Even though bacteria have some disadvantages, Escherichia coli is still one of the most commonly used organisms for the production of recombinant proteins [1-3].The over-expression of recombinant proteins in bacteria often leads to their aggregation
Selenium induced lower respiratory potential in Glycine max (L.) Merr
pela Mechora, Mateja Germ
Acta agriculturae Slovenica , 2010, DOI: 10.2478/v10014-010-0004-2
Abstract: Effect of selenium (Se) was studied in soybean (Glycine max (L.) Merr.) cv. Olna in Ljubljana, Slovenia. Se was added to plants as foliary spraying. Quantum yield of photosystem II (PSII) and respiratory potential measured as ETS activity of mitochondria were measured two times in the growing season. Respiratory potential was higher in young plants compared to mature plants. Se induced the lowering of respiratory potential. Addition of Se had no effect on quantum yield of photosystem II.
Geographical Location of Depopulation Areas in the Czech Republic and its Dependence on Transport Infrastructure: Part I: Definition, Methodology, and Quantitative Analysis
E. Drápela
Transactions on Transport Sciences , 2011, DOI: 10.2478/v10158-011-0005-9
Abstract: Location of settlement at important routes of transport was always one of the key factors for its prosperity. However, in the car-oriented world of today the distance factor is not so important for many people and they prefer to live in calm rural areas. Simultaneously, many rural areas in peripheral locations are affected by the emigration of inhabitants and global decay. This study explains how good transport infrastructure should be beneficial for rural areas and how it is in reality in the Czech Republic. The study is a part of a larger work of research, based on component analysis of localization of depopulation areas in the Czech Republic between the years 1869 - 2010. The role of transport is documented not only by the localization of the transport infrastructure, but also by the duration and orientation of commuting to work. Theories and premises are supported by quantitative analysis in all municipalities in the Czech Republic and also by three in-depth case studies, oriented more on qualitative indicators.
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