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Search Results: 1 - 10 of 1253 matches for " ?ner ?zdemir "
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Mechanisms of preventative and therapeutic role of probiotics in different allergic and autoimmune disorders  [PDF]
nerzdemir
Open Journal of Immunology (OJI) , 2013, DOI: 10.4236/oji.2013.33015
Abstract:

The prevalence of allergic and autoimmune diseases has been increasing from the last decades of 20th century. Intestinal microflora contributes to antigen exposure in early life and is one of the most abundant sources of early immune stimulation as well as adaptation. Because allergic and autoimmune responses manifest early in life, there has been obvious interest in the potential benefits of modifying the gastrointestinal flora by using probiotic supplementation. So far, there have been several studies to address the role of probiotics in primary prevention and therapy, with a reported suspicious reduction in the incidence of atopic and autoimmune diseases. Here, our aim is to evaluate the available knowledge of mechanisms of preventative and therapeutic role of probiotics in different allergic and autoimmune disorders. Promising mechanisms of probiotic effects may be categorized as local and systemic effects. Local influences of probiotics potentially include reduction of gut permeability and systemic penetration of antigens, increased local immunoglobulin A production, and alteration of local inflammation or tolerance induction. Some possible systemic effects consist of anti-inflammatory effects mediated by Th17 cells and Toll-like receptors, Th1 skewing of responses to allergens, activation of tolerogenic dendritic cells, in addition to T-regulatory cell production.

Food protein induced proctocolitis in neonatal and infantile period: Clinical, endoscophic, hystopathologic findings and therapy
nerzdemir
Turk Pediatri Ar?ivi , 2009,
Abstract: ..
Letters to the Editor
nerzdemir
Cocuk Enfeksiyon Dergisi , 2009,
Abstract:
Nighttime feeding in Turkish children and its association with anemia  [PDF]
Metin Trabzon, Melih Abdullah Turun?kap?,nerzdemir, Melike Sultan ?zg?nenel, Damla ?nce, Bülent ?zg?nenel
Open Journal of Pediatrics (OJPed) , 2012, DOI: 10.4236/ojped.2012.21011
Abstract: Background: Children who continue to wake up at night to be fed after 6 months of age are called trained nighttime feeders. Nighttime feeding may be associated with dental and medical complications, in addition to causing sleep deprivation in children and parents, as well as with iron-poor nutrition. Methods: We surveyed 614 Turkish children aged 6 months to 5 years from three centers (2 urban and 1 rural) to determine the prevalence of nighttime feeding. We also sought to determine factors associated with continuation of nighttime feedings after 6 months of age. Results: Fifty percent of the participants were night- time feeders. Nighttime feedings were given once, twice, and three times or more to 19.9%, 15.6%, and 14.5% of the participants, respectively. The rural population had a higher rate of nighttime feeding (57.0% rural vs 46.6% urban, p = 0.016). 168 urban children (median age 25 months) had blood count data. Fifty percent of these children were given night-time feedings: 19.6% once, 17.9% twice, and 12.5% three times or more. Nighttime meals were breast-feeding in 51.2%, cow’s milk by bottle in 33.3%, and other in 15.5%. Mean hemoglobin level of nighttime feeders was significantly lower: 11.3 ± 1.3 g/dL vs 12.2 ± 1.0 g/dL in non-nighttime feeders (p < 0.001), even dropping to 10.8 ± 1.4 g/dL in those that were fed 3 times or more at night (p < 0.001). 31.0% of nighttime-feeders were anemic compared to 17.9% in those that did not receive nighttime feedings (p = 0.048). We also noted that intense nighttime feeding was associated with lower MCV (p < 0.001) and lower ferritin levels (p < 0.001). Conclusions: Nighttime feeding is prevalent among Turkish children, especially among the rural population. Nighttime feeding was also noted to be associated with anemia in this study. Nighttime feeding should be screened for and treated in children after 6 months of age.
Current and Future Concepts in Treatment of Childhood Atopic Dermatitis Review
Elif Karako? Ayd?ner,Safa Bar??,Cevdet ?zdemir
Güncel Pediatri , 2011,
Abstract: Atopic dermatitis (AD) is a chronic inflammatory skin disorder caused by a dysregulation of immune response to allergenic or non-allergenic stimuli. Interplay of several effector cells including migrating lymphocytes, fibrocytes, Langerhans cells, mast cells and epidermal keratinocytes enroll in the development of AD. Atopic dermatitis affects approximately 20% of children and persists in 6% of adults. Relieving acute exacerbations, improving the quality of life and prevention of side effects in the long term are the main steps of the management of AD. Mild to moderate cases can be controlled with avoidance of triggering factors, skin care and topical medications. In severe cases immune suppression is an option with cumulative toxicity and variable efficacy of drugs as a limiting factor. It is essential to develop safer and efficacious alternatives for the treatment of AD, especially in pediatric age group. (Journal of Current Pediatrics 2011; 9: 39-43)
Benign childhood acute myositis: clinical and laboratory findings of 15 cases
Sema Salt?k,Murat Sürücü,nerzdemir
Turk Pediatri Ar?ivi , 2012,
Abstract: Aim: In this study; clinical and laboratory findings of 15 cases with benign childhood acute myositis are presented to look over pathognomonic findings of the disease.Material and Method: Fifteen typical cases with benign childhood acute myositis referred to our Pediatric Neurology Clinic because of inability to walk, from 15th of January to 15th of March 2011, were enrolled into this study. Eighty percent of cases were male and their mean age was 6.3 years. Guillian-Barre’s syndrome was the most common initial diagnosis (47% of the cases).Results: Prodromal period lasted 2- 10 days and common symptoms were sore throat, fever and cough. When they were referred to our clinic, the patients complained of pain in both calves and inability to walk. In three days period; the symptoms resolved fast and spontaneously. Leucopenia at 87%, thrombocytopenia at 47%, mildly high alanine transaminase at 87% of the patients were detected. Serum creatinin kinase level ranged from 580 to 8250 U/L and it regressed to normal level within one week.Conclusions: In the patients of whom clinical and laboratory findings are suggestive of benign childhood acute myositis, it is important to think early diagnosis, which prevents unnecessary laboratory evaluations and therapeutic approaches. (Turk Arch Ped 2012; 47: 52-5)
Effect of immediate implant placement and loading on soft tissue management  [PDF]
Erdem ?zdemir, Yener Oguz
Open Journal of Stomatology (OJST) , 2013, DOI: 10.4236/ojst.2013.37066
Abstract:

The recent article describes immediate implant placement and loading in the anterior segment. The main aim of this treatment option was to deliver provisional prosthesis to the patient in the same day of surgery, form papilla contours, and eliminate waiting of osseointegration time and the second surgery.

Thiol-Disulphide Balance: Could Be a New Marker for Thyroid Cancer?  [PDF]
Ay?e ?zdemir, ?zcan Erel
Journal of Cancer Therapy (JCT) , 2018, DOI: 10.4236/jct.2018.98051
Abstract: Objectives. Cancer is a very widespread disorder known in world wide since long, but its biochemical features remain unclear. Thyroid carcinomas are the most common endocrine cancer and its frequency continues to escalate. There is evidence that the serum concentration of TSH is an unreliant predictor for the diagnosis of thyroid cancer. The formation of the plasma thiol pool from low and large molecular weight proteins suggests that thiol/disulfide balance is important in cancerous cases. The aim of this study was to investigate an oxidative stress marker (thiol/disulphide homeostasis) and IMA (Ischemia modified albumin), Albumin, CEA (Carcinoembryonic antigen), TSH (Thyroid stimulate hormone), thyroxine (T4), free thyroxine (FT4), triiodothyronine (T3) and free triiodothyronine (FT3) in patients with thyroid cancer and compare the results with healthy controls for the first time in literature. Materials-Methods: A total of 43 participants including 23 patients with thyroid cancer and 20 healthy individuals were included in the study. Serum levels of TSH, T4, FT4, T3 and FT
The Relation between Liberty and Dependence in Rousseau’s Philosophy of Education
Ismahan ?zdemir
Beytulhikme : An International Journal of Philosophy , 2012,
Abstract: In this paper, the contradiction between freedom and dependence which are the concept included within philosophy of education of Rousseau will be examined. Rousseau asserts that humans who are inherently good are corrupted by the social institutions and seeks for a method of bringing up a good person. However the issue which he ignores while seeking for a method is the relation between tutor and pupil. Rousseau who intends to bring up free and good person cannot save the pupil from the bonds of slavery which he asserts to be adopted in the process of socialization. This side of Rousseau’s educational model will be explained in this study.
Osmanl Devleti'nde Sa l k Alan nda Yap lan Misyonerlik Faaliyetlerine Bir rnek: Amerikan Board'un Konya T bb Misyonu/// An Example of Missionary Activities in the Medical Field in the Ottoman Empire: The Medical Mission of the American Board in Konya
Emin ?zdemir
History Studies : International Journal of History , 2013,
Abstract: This article examines the missionary activities of the American personnel in the American Christian Hospital of Konya, which was opened by the missionaries of the American Board in 1912. According to Ottoman sources, although the Ottoman authorities were aware of the explicit missionary effort to proselytize the local Muslim population, they allowed the hospital to remain open until World War I. Later on the hospital was reopened and reclosed several times until it was closed permanently in 1923.
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