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Search Results: 1 - 10 of 85237 matches for " 黄?先 "
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黔北火电厂周边森林土壤重金属污染现状研究
Study on Heavy Metals Pollution of Forest Soils around Qianbei Coal-Fired Plant
 [PDF]


Advances in Environmental Protection (AEP) , 2016, DOI: 10.12677/AEP.2016.64010
Abstract:
为探索山区火电厂周边森林土壤重金属污染现状,调查了贵州省黔北火电厂周边7个森林样地物种群落结构概况,在7个森林样点的中心部分、林地边缘及林外耕地进行了土壤样品采集,分析研究了土壤样品中铅、镉、汞、砷、铜与铬6中重金属的污染水平。结果表明林地土壤重金属Pb基本源于土壤形成的基岩,受外界污染较小。林地植被对大气沉降引起的Pb污染具有较好屏蔽效果,但对Hg、Cd两种元素的屏蔽效果相对较弱,主要受林分与密闭度的影响。基于贵州省土壤背景值及单因子指数与综合污染指数法评价结果,研究区土壤主要存在Hg、Cd、Pb的污染,而As、Cu及Cr则不存在污染现象。
To study the heavy metals pollution status of soils from forest land surrounding coal-fired plant in mountainous area, species community structures of 7 forest lands surrounding Qianbei Coal-fired Plant were investigate. Soil samples were collected at central parts and edge parts of these forest lands, and soils in cropland out of these forest lands were sampled as well. Pollution levels of Pb, Cd, Hg, As, Cu and Cr were analyzed. The results suggested that Pb in soils of forest land was mainly associated with rock weathering; forest trees are good shields against the Pb pollution caused by atmospheric deposition. For Hg and Cd pollution, its protection primary depended on its forest closure and components. According to the single factor and Nemerow comprehensive index method, study region was polluted with Hg, Cd and Pb, and no pollution of As, Cu and Cr in these areas was observed.
反向药理学和基于传统药物的现代镇痛药的研发
Reverse Pharmacology and the R&D of Modern Analgesic Based on Traditional Medicines
 [PDF]

陈素, , 刘向明
Traditional Chinese Medicine (TCM) , 2012, DOI: 10.12677/tcm.2012.11001
Abstract: 疼痛是许多急慢性疾患中皆可出现的症状,它是危及人类健康及防碍正常生活的主要问题之一。为了抗御疼痛,人类一直在孜孜不倦地寻求镇痛药物。目前临床上使用最多的镇痛药是以吗啡为代表的阿片生物碱类及其合成代用品(或称阿片类药物——opioids)和非甾体抗炎药(Nonsteroidal Antiinflammatory Drugs,NSAIDs),它们都有较为严重的毒、副作用。一些致痛因子和炎性介质,如5-HT,ATP,BK,His,PGE2,SP等,其相应的受体阻断剂的应用对于镇痛虽有一定效应,但由于此等受体分布广泛,故选择性作用部位不强而且副作用也较多。因此关注的焦点主要集中在探索表达于中、小直径的初级感觉神经元的河豚毒素不敏感型(tetrodotoxin-resistant,TTX-R)钠通道和瞬时感受器电位香草酸受体1(transient potential vanilloid receptor1,TRPV1)。遗憾的是多年来在这方面并无突破性进展。以植物为本的各民族传统药物是当今国际药品市场的潜在丰富来源。遵循“反向药理学”的研究模式,形成先导物发现可践行的方法学,结合先进的科学技术和方法,从长期临床应用证实具有较显著镇痛功效和较少毒、副作用的传统药物中提取、分离多种单体化学成分,对其进行系统的药理研究,开发出化学结构和镇痛机理明确、安全性高的新型镇痛药物,将是镇痛药研发中具有较高效率的新途径。在我们的研究中,发现了两种对TTX-R钠通道和TRPV1均具有调制作用的民族药物——龙血竭和野木瓜。这两种药物在临床上都有较好的镇痛疗效,并且无成瘾性方面的记录。我们还确定了龙血竭调制TTX-R钠通道和TRPV1的药效物质基础是其化学成分剑叶龙血素A、剑叶龙血素B和龙血素B的组合。
Pain is a major symptom in many medical conditions, and can significantly interfere with a person’s quality of life and general function. To relieve pain, people are unwearied to look for the analgesic drugs. Nowadays, the most popular analgesics in clinic practice are opioids and non-steroidal anti-inflammatory drugs (NSAIDs), both of which have some adverse reactions. Although the antagonists of some painful factor such as 5-HT, ATP, BK, His, PGE2 and SP receptors can relieve pain to some extent, they have some unpleasant side-effects and low selectivity for analgesic sites due to the wide distribution of them. Therefore, the focus of the research was concentrated on tetrodotoxin-resis- tant (TTX-R) sodium channel and transient potential vanilloid receptor 1(TRPV1) distributed in small-to-medium-sized primary sensory neurons. However, little breakthrough has been made for the past many years. The plentiful plant-derived national traditional medicine are potential resource of international pharmaceutical market nowadays. Based on the research framework of reverse pharmacology, combined with advanced science technique and methods, shaping into feasible methodology of discovering lead compounds, a new approach of developing analgesics is to ex- tract and separate various monomers from traditional medicine which have been confirmed significant efficacy and low side effect in clinic practice for a long period. The monomers will then be investigated systematically and developed into new analgesics with identified chemicial construction, clear-cut mechanism and high security. Our study discovered that two ethnodrugs, Dragon’s Blood Resin and Stauntonia chinensis DC., could interfere with pain messages and modulate TTX-R sodium and TPVR1 channels. They could produce excellent analgesic therapy in clinic without drug
植物开花控制基因FLOWERING LOCUS T (FT)功能多样性的研究进展
Progress on the Multifaceted Roles of Flowering Control Gene FLOWERING LOCUS T (FT)
 [PDF]

郭丹丽,
Botanical Research (BR) , 2014, DOI: 10.12677/BR.2014.36028
Abstract:
高等植物开花转变过程中,FLOWERING LOCUS T (FT)基因编码的蛋白产物是可以长距离转运的成花激素,是植物成花转变过程中的关键调控因子。目前研究发现,在一些植物中FT基因不仅可以促进植株成花,还表现出抑制植物开花的特性。同时,研究表明FT基因参与到控制植株坐果、营养生长、气孔开放、促进结薯和侧枝生长等发育过程。本文主要回顾了FT基因近几年的研究进展,为进一步深入了解和研究FT-like亚家族基因的功能提供了理论依据。
The FLOWERING LOCUS T (FT) protein, a mobile signal recognized as a major component of florigen, has a central position in mediating the floral transition. Recent research showed that FT gene not only promoted flowering, but in some plants FT also showed the function of inhibition of plant flowering. At the same time the function of FT gene has also been identified as a major regulatory factor in a wide range of developmental processes, such as fruit set, vegetative growth, stomatal control, tuberization, and branches elongation. This article reviewed the latest pleiotropic functions of FT and its orthologs in plant development, providing a theoretical basis for further study about the function of FT-like gene sub-family.
她给我插上奋飞的翅膀

现代物理知识 , 1991,
Abstract: 夜,静极了.南大校园里,灯火通明.象往常一样,做完了功课、预习之后,又翻阅我生活中的伴侣——《现代物理知识》,仿佛只身在北京正负电子对撞机实验大厅里,聆听王淦昌、张文裕、赵忠尧、朱洪元教授给我讲解物理新发现…….我是一个物理系四年级学生,平时学了不少系统的物理知识,但对许多高深物理知识究竟有什么用,心中总感到迷惑,甚至怀疑现代物理是否陷入繁杂的数学推理之中,变成脱离实际的抽象理论学科.读了《现代物理知识》,对现代物理学的进展与应用有所了解,使我眼界顿开;它介绍的各种新奇的物理思想、实验和重大发现,使我惊叹不已,激起了我对学物理、用物理的强烈兴趣,心中所有的疑虑也烟消云散了.学校不是真空.随着各种思潮的冲击,在我周围有不少人感到读书无用,学物理更无出路.我自己也
天竹黄形成原因及人工结天竹黄试验初步研究

科学通报 , 1973,
Abstract: 前言天竹黄(Concretio Silicea Bambusae)又名竹黄,是我国临床应用悠久的中药。主治热病,神昏谵语,中风痰迷不语,小儿惊风抽搐等病。产于我国广东、广西、云南等省区。广东主产于广宁县。天竹黄虽属竹子的天然副产物,但由于过去对其形成原因不甚了解,无法进行人工生产,致使其天然产量不能与我国人民卫生事业发展的需要相适应。为了改变这种状
十二指肠钩虫体外培养的研究——从14天龄童虫培育至产卵成虫的观察

科学通报 , 1988,
Abstract: 关于十二指肠钩虫成虫的体外培养,1960年Yasuraoka和1979年王风临等曾有报道。但有关将童虫培养到成虫的研究,则除了作者曾将17天龄的十二指肠钩虫的童虫成功地培养至成虫外(中华医学杂志,67(1987),2:96—98),尚未见其他类似的报道。
德国行政诉讼中司法权的边界及其成因

比较法研究 , 2013,
Abstract: 德国行政诉讼中法院的受案范围非常广泛;法院一般可以主动、全面、深入地审查案件中的事实问题、行政裁量权问题以及法律问题等,无须尊重行政机关的专业知识与经验。不过,自上个世纪70年代以来,随着有关解释不确定法律概念的理论的发展,德国行政法院对行政机关进行强势监督与制约的格局有所松动。同时,值得注意的是,行政法院在判决与执行中恪守权力分立的原则。德国行政诉讼中司法权边界的形成,是与其宪政体制、法院分工格局、法定法官原则、二战后对公民权利的重视以及发达的公法理论等紧密相关的。
浅谈我所知识结构和人才培训

公路交通科技 , 1984,
Abstract: 近年来,从中央到地方,各单位、各部门将职工教育、人才培训工作列入重要议事日程,并设置专门机构,组织专职人员负责日常工作。
计量学方法在人才管理中的应用

公路交通科技 , 1985,
Abstract: 概述随着现代科学技术的迅速发展,科学计量学的研究和应用也日趋深入广泛起来.诸如对科学潜力状况的评价、科研发展趋势的分析以及科研成果的价值、效益的估计等等.凡涉及科学技术领域,在计量数量指标变化的同时,强调某些质量指标的量化,以便准确地为科研实践提供依据和各种可比性的结论,都离不开科学计量方法.
十二指肠钩虫体外培养的研究——从14天龄童虫培育至产卵成虫的观察

科学通报 , 1988,
Abstract: 关于十二指肠钩虫成虫的体外培养,1960年Yasuraoka和1979年王风临等曾有报道。但有关将童虫培养到成虫的研究,则除了作者曾将17天龄的十二指肠钩虫的童虫成功地培养至成虫外(中华医学杂志,67(1987),296—98),尚未见其他类似的报道。
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