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Search Results: 1 - 10 of 83863 matches for " 邓青辉 "
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基于Pearson系数与多元核支持向量分类的葡萄酒分析
,伟民,陈晓
农业机械学报 , 2014, DOI: 10.6041/j.issn.1000-1298.2014.01.032
Abstract: 选择Pearson相关系数筛选出与红葡萄酒各理化指标相关性较强的酿酒红葡萄理化指标,用逐步回归法建立回归方程确定了它们之间的数量关系。同时,采用多元核支持向量机对红葡萄酒样品进行分类,所分类别与人工口感评分所分类别基本相符,正确率达到91.89%,结论表明酿酒红葡萄和红葡萄酒的理化指标能很好地确定葡萄酒的口感评价。
两种具有螺旋结构的双核铜有机-无机配位聚合物的合成及表征
赵仑,张敏,,王子忱
- , 2015,
Abstract: 摘要 在水热和溶剂热条件下, 有机多齿羧酸4,4'-三苯胺二甲酸(H2L)及含铜化合物分别与2,2'-联吡啶(bpy)和1,4-二(吡啶-4-甲氧基)苯(bpmb)反应, 合成了2种新型的含铜配位聚合物[Cu2L(bpy)](1)和[CuL(bpmb)0.5]·DMF(2). 通过X射线单晶衍射、 红外光谱、 元素分析、 热重和粉末X射线衍射分析等对其结构进行了表征. 结果表明, 化合物1属正交晶系, Pnma空间群, 其骨架为二维层状结构; 化合物2属单斜晶系, P21/c空间群, 具有{44·610·8}拓扑结构的三维网络
2-氨基-4,5-二取代烃嘧啶类衍生物的新合成方法有机化学
, 徐中海, 尚云峰, 戴文静,, 穗平, 欧阳健明
有机化学 , 2012, DOI: 10.6023/cjoc1109222
Abstract: 研究了2-氨基-4,5-二烃基取代嘧啶类衍生物的一个新的简易合成方法,该方法以简单且廉价的4个芳香醛和3个脂肪醛为原料,经过四步反应得到12个2-氨基-4,5-二烃基取代嘧啶类化合物,总收率在40%~70%,经氢核磁共振(1HNMR)、碳核磁共振(13CNMR)和高效液质联用(LC-MS)对其目标产物进行表征.
Single nucleotide polymorphisms in 22 HLA-Cw alleles in Chinese Han population
汉族人群中22个HLA-Cw等位基因全长序列单核苷酸多态性分析

曾健强,徐筠娉,王大明,高素,邹红岩,
遗传 , 2010,
Abstract: To analyze the molecular genetic polymorphism of full-length HLA-Cw gene, a total of 28 samples with known genotypes from Chinese Han population were amplified by long-range PCR using high-fidelity Pfu polymerase. A fragment 4.5 kb in length of HLA-Cw gene was subjected to cloning and haplotype sequencing. The single nucleotide polymorphisms (SNPs) in all segments of the whole region of HLA-Cw gene were analyzed. As a result, we detected 22 different HLA-Cw alleles in 28 samples, all of which were submitted to GenBank and the IMGT/HLA Database. Among the 22 HLA-Cw alleles, the intronic sequences of Cw*030301, Cw*0706 and Cw*140201 were firstly elucidated. The novel intronic sequence and the SNPs information may help to design allele-specific primers for accurate sequence-based typing (SBT) and to avoid allele dropout events in SBT test. We aligned all the diploid sequences using ClustalX program and imported them into Dnasp4.0 to calculate polymorphism in all coding- and non-coding regions. We found 244 SNPs and 10 insertion/deletions (Indels). According to the analysis of polymorphism level, phylogenetic trees and frequency spectrum, we proposed that the evolution of intron 4 and exon 5 was under balancing selection. Selection on these segments indicated that they may be functionally important in evolution of HLA-Cw gene. The full-length sequences obtained and related SNPs information can be used as resources of markers for high-resolution typing, complex diseases association studies and human evolution.
基于ERC-PCR的环境内分泌干扰物检测体系研究
谭文婷,罗霄,晏泽,但芸婕,,国宏
第三军医大学学报 , 2010,
Abstract: 目的利用雌激素与雌激素受体α(estrogenreceptorα,ERα)间基于配体受体激活效应的生物学原理和探针的定量PCR扩增-实时荧光检测技术,建立痕量环境内分泌干扰物(endocrinedisruptingcompounds,EDCs)的快速检测体系。方法以2条含雌激素反应元件(estrogenresponseelements,ERE)并与ERα有高亲和力的DNA序列COX7RP-ERE和VitA2-ERE,作为结合探针,进行ERα体外受体?配体特异结合,形成配体-ERα-DNA探针复合体(ERα-DNAprobecomplex,ERC),荧光定量检测ERE含量,并考察17β?雌二醇(E2)、雌酮(E1)、己烯雌酚(DES)及邻苯二甲酸二甲酯(DMP)的结合情况。结果与VitA2-ERE相比,人源性COX7RP-ERE在ERα体外受体-配体结合过程中具有更好的结合效应;E1、E2、DES、DMP4种雌激素类化合物对COX7RP-ERE的结合存在明显的剂量-效应关系,其对COX7RP-ERE结合效应的半数有效浓度(EC50)分别为0.89nmol/L、19.9pmol/L、0.79nmol/L、6.31pmol/L。结论检测体系中结合探针的结合量存在明显的雌激素剂量依赖性,这种基于ERα激活效应的ERC?PCR定量检测体系可以用于监测化合物和EDCs的类雌激素活性。
老年重症肺炎并呼吸机相关性肺炎的病原学观察
郭振,青南,孙杰,苏磊,唐柚,麦悦强
第三军医大学学报 , 2007,
Abstract: 目的探讨老年重症肺炎并机械通气(mechanicalventilation,MV)后再感染呼吸机相关性肺炎(ventilatorassociatedpneumonia,VAP)病原学及其变化。方法对34例老年重症社区肺炎入院时和及其VAP发生后,获取下呼吸道分泌物行定量培养、药物敏感性与ESBLs检测。结果①病原:入院时以G-杆菌为主;VAP发生时,G-杆菌由75%增加到87%,其中,非发酵类细菌病原检出率也由24%上升至37%。ESBLs检出率由32%上升至47%;混合感染和“二重感染”分别由12%、9%上升至59%和35%。②对常用抗生素的药物敏感性试验:入院时G-杆菌菌株,除对亚胺培南无耐药外,含酶抑制剂抗生素、头孢他啶,阿米卡星、拉氧头孢耐药率在20%~30%;对其余三代头孢和哌拉西林、环丙沙星耐药率为40%~50%;而VAP时G-杆菌菌株,则出现了对亚胺培南耐药菌株,耐药率的高低与入院菌株趋势大致相似,但增加12%~20%;产ESBLs菌株除亚胺培南、含酶抑制剂抗生素、拉氧头孢外,比非产ESBLs菌株耐药率高30%~50%。③病死率53%。结论老年重症CAP及其VAP病原均以G-杆菌为主和较高的ESBLs检出率,VAP时非发酵类细菌病原、白色念珠菌比例和ESBLs检出率均大幅增加,老年重症CAP及其VAP在抗感染治疗及抗生素选用时应充分考虑病原学的以上特点。
磺基水杨酸盐的晶体结构和倍频效应
李悦,立志,周晓海,张绍,杨清传
物理化学学报 , 1998,
Abstract: 用x射线单晶衍射法测定了三水合二(5-磺基水杨酸)钙(c(14)h1(10)o(12)s2ca?3h2o,1)和二水合(5-磺基水杨酸)二钾(c7h4o6sk2?2h2o,2)的晶体结构.化合物1属单斜晶系,空间群为pn,晶胞参数a=5.604(1)?,b=18.560(4)?,c=10.006(2)?,β=102.19(3)°,z=2,最终r=0.0244.化合物2属正交晶系,空间群pbca,晶胞参数a=25.841(5)?,b=12.186(2)?,c=7.739(2)?,z=8,最终r=0.0308.化合物1粉末倍频效应为2.86倍kh2po4,其厘米级单晶体的紫外端吸收边经在375nm附近.
湛江特呈岛红海兰混交群落种内种间竞争的研究
Intraspecific and Interspecific Competition of Rhizophora stylosa in Techeng Isle of Zhanjiang

黄月琼,江加,刘素,,黄巧绵
- , 2015, DOI: doi:10.3969/j.issn.1001-7461.2015.03.12
Abstract: 利用Hegyi提出的单木竞争指数模型分析湛江市特呈岛红海兰混交群落种内和种间竞争指数。结果表明,红海兰种内种间竞争指数随着林木径级增大而减少;径级在3.0~3.9 cm时受到的竞争强度最大;种内竞争远大于种间竞争;种间竞争强度的顺序为海榄雌>木榄>秋茄树;红海兰种内、种间和林分竞争强度服从幂函数关系。
Using intraspecific and interspecific competition of Rhizophora stylosa occurring in Techeng Isle of Zhanjiang were analyzed by using Hegyi’s competition index model for individual tree. The results showed that intraspecific and interspecific competition index of R. stylosa reduced with the increase in diameter scale of the trees. The competitive intensity reached the maximum when the diameter class was between 3.0 cm and 3.9 cm. The intraspecific competition was much larger than interspecific competition.The order of interspecific competition was listed as:Avicennia marina>Bruguiera gymnorrhiza>Kandelia candel. The intraspecific and interspecific, as well as forest stand competitive intensities of R. stylosa matched the power function CI=ADB
杉木连栽对土壤物理性质的影响
俞元春,西海,盛炜彤,范少,林庆祥,雷凌
南京林业大学学报(自然科学版) , 2000, DOI: 10.3969/j.jssn.1000-2006.2000.06.008
Abstract: <正>在福建省南平市花岗岩母质的林地上,应用生态系列法对不同栽植代数、不同立地条件和不同林分年龄的系列杉林样地土壤的物理性质进行了研究。结果表明,杉木连栽对土壤容重和孔隙状况的影响主要在林分的中龄林时期。随着栽植代数的增加,土壤容重趋于增加;对于幼林和成林,由于受整地、抚育和林下植被的恢复及枯枝落叶的分解,不同栽植代数对土壤孔隙状况的影响不甚明显;不同栽植代数对土壤水分性能的影响主要表现在中龄林和成熟林时期。表层土壤的持水能力一般随栽植代数增加而下降,土壤的渗透性能趋于降低,地位指数愈高,这种下降趋势愈明显
甲状腺疾病所致气管狭窄的发生和处置
唐柚,郭振,周娟,叶曜芩,邹霞英,清南
南方医科大学学报 , 2005,
Abstract: 目的探讨甲状腺疾病所致气管狭窄发病的特殊性及其诊疗对策。方法回顾10例不同原因甲状腺疾病所致气管狭窄的误诊情况、诊断方法包括纤支镜检查和/或颈部ct检查,甲状腺扫描和病理检查;处理方法包括甲状腺切除手术和人工气道重建。结果10例甲状腺疾病所致气管狭窄患者中,误诊为“支气管哮喘”3例,误诊为急性左心衰2例;经纤支镜检查和/或颈部检查均可见气管外压性ⅱ~ⅲ度狭窄;甲状腺疾病经病理检查确认。人工气道重建后均可缓解气管狭窄,以气管内支架置入术效果最佳,气管切开套管置入次之。结论甲状腺疾病所致气管狭窄易于误诊,提高警惕性则诊断不难;甲状腺切除手术和人工气道重建可有效缓解气管狭窄,但预后取决于甲状腺疾病性质、狭窄程度和处理方法。
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