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More than 80% of the patients with ovarian cancer chemotherapy relapse due to drug resistance, which makes the highest ovarian cancer mortality rates among the gynecologic malignancies. Compared with the highly heterogeneous tumor cell differentiation, tumor stroma cells have genetic stability, and it is unlikely to produce acquired mutations and lead to drug resistance. In view of the treatment strategies for tumor interstitium, ovarian cancer is reviewed in this paper. At the same time, we pointed out the direction for reducing toxicity, preventing the cancer recurrence and metastasis, improving the survival rate in the treatment of gynecologic malignancies.
杜仲树是应用潜力比三叶橡胶树还大的优质天然橡胶资源。但是杜仲胶的提取难度制约了杜仲胶的应用和发展。利用酶处理工艺替代传统的化学、微生物、机械处理工艺，则能实现提胶生产污染防治由“末端治理”向“源头预防\"的转变。且酶处理方法的多种天然产物的同时提取，显著降低了生产成本，提高产品经济效益。更主要的是酶法可获得原生态的天然杜仲胶，提高了杜仲胶的应用领域和工业价值。本文以可以再生的杜仲叶为原料，对杜仲叶的组织结构和酶解机理进行了研究，以及在生产的应用的研究进行了讨论。Eucommia ulmoides is a kind of natural rubber resources whose potential application is greater than Hevea. But the difficulty of extracting gutta percha restricts the application and development of gutta percha. Instead of traditional treatment process using chemical, microbial, mechanical processing techniques, utilization of enzyme can control the pollution during the extraction from the “governance at the end” to “prevention from source”. At the same time, various natural products can be obtained when treated by enzyme method, which can reduce the production cost and improve economic benefits. More importantly, the enzyme method can obtain the original ecological natural gutta percha. Furthermore, the application fields of gutta percha and industrial value are increased. In this paper, the solution mechanism of enzyme and the organizational structure of Eucommia ulmoides leaves were studied with the recycled Eucommia ulmoides leaves used as raw material, and the production and application were discussed.