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Iron is an essential element for cell growth. The iron contents in tumor cells are higher than those in normal cells. The addition of exogenous iron can prevent apoptosis while iron chelators can inhibit the growth of tumor cells. Therefore, the anti-tumor effect of iron chelators obtains more and more extensive concern. This article aims to present a review on recent advancements in studies of iron and cervical cancer, and to explore the mechanism of iron in initiating cervical cancer as well as the effects of iron chelators on treatment of cervical cancer.