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Search Results: 1 - 10 of 4650 matches for " ángela; Cardona Maya "
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Posible relación entre el uso de isotretinoína y la presencia de globozoospermia
Pe?a,Ruth Beatriz; Cadavid,ángela; Cardona Maya,Walter;
Revista Cubana de Obstetricia y Ginecolog?-a , 2011,
Abstract: isotretinoin was tested for treatment of acne from 1982 and nowadays is used for treatment of a wide number of skin alterations. among the recommendations of the american academy of dermatology consensus conference is included the non-use of this treatment in pregnant women, however, it is not mentioned the potential risks in sexual and reproductive men health, group in which is commonly used for treatment of acne.
Posible relación entre el uso de isotretinoína y la presencia de globozoospermia Possible relationship between Isotretinoin use and globozoospermia
Ruth Beatriz Pe?a,ángela Cadavid,Walter Cardona Maya
Revista Cubana de Obstetricia y Ginecolog?-a , 2011,
Abstract: La isotretinoína fue aprobada para el tratamiento del acné desde 1982 y en la actualidad es usada para el tratamiento de un amplio número de alteraciones dermatológicas. Entre las recomendaciones de la American Academy of Dermatology Consensus Conference está no usar este tratamiento en mujeres embarazadas, sin embargo no se hace mención a los posibles riesgos en la salud sexual y reproductiva masculina, población en la cual también es comúnmente usado este medicamento para el tratamiento del acné. Isotretinoin was tested for treatment of acne from 1982 and nowadays is used for treatment of a wide number of skin alterations. Among the recommendations of the American Academy of Dermatology Consensus Conference is included the non-use of this treatment in pregnant women, however, it is not mentioned the potential risks in sexual and reproductive men health, group in which is commonly used for treatment of acne.
Evaluación de la reacción acrosomal inducida por el ionóforo de calcio: una aproximación mas real de la capacidad fecundante del espermatozoide
Cardona Maya,Wálter Darío; Olivera ángel,Martha; Cadavid,ángela Patricia;
Archivos Espa?oles de Urología (Ed. impresa) , 2006, DOI: 10.4321/S0004-06142006000500007
Abstract: objectives: the aim of this investigation was to evaluate the acrosome reaction by fluorescence microscopy and the .ow citometry in a group of men with unknown fertility. methods: each individual gave a semen sample for the analysis of the calcium ionophore-induced acrosome reaction after the capacitation process, using lectin pisum sativum aglutinina (fluorescence microscopy) and antibody anti-cd46 (flow citometry). results: five of out six individuals increased the number of the sperm with calcium ionophore-induced acrosome reaction versus the percentage of spontaneous acrosome reaction, using fluorescence microscopy (7.4 +/- 2.4 vs 22.5 +/- 10.1) and .ow citometry (8.5 +/- 2.8 vs 25.4 +/- 6.0); on the other hand, the other individual the values of the acrosomal reaction with calcium ionophore a23187 were similar to those of the spontaneous reaction. conclusions: both techniques are useful to evaluate the in vitro capacity of the spermatozoa to undergo acrosomal reaction, after the capacitation, without fusion between the sperm and the egg, but the .ow citometry is more objective and allow the detection of a higher cell numbers of cells. on the other hand, although the individual that did not respond to the stimulus with calcium ionophore has unknown fertility, the obtained results allow to propose that the evaluation of the acrosomal reaction could be a useful tool in the study of the men who consult for infertility.
Muerte embrionaria temprana: ?Tiene influencia el factor masculino?
Gil Villa,Aura María; Cardona-Maya,Wálter Darío; Cadavid Jaramillo,ángela Patricia;
Archivos Espa?oles de Urología (Ed. impresa) , 2007, DOI: 10.4321/S0004-06142007000900002
Abstract: objective: to discuss the possible role of the male factor in early embryo death. method: a detailed bibliographic review has been put together to establish which alterations in spermatozoa can be associated with early embryo death. results: before the fusion between plasma membranes of the sperm and the oocyte occurs, both germ cells must undergo a maturation process that allows successful fertilization and embryo development. the study of couples with early embryo loss is usually approached from the side of the woman due to the obvious relationship that exists between the female and the developing embryo. however, it is not illogical to suppose that a genetic or epigenetic alteration of the sperm could have important consequences on these losses due to the necessary contribution of the male gamete not only to embryonic but also to placental development. on the other hand, spermatozoa have certain characteristics such as a highly compact dna, they undergo apoptosis and the seminal plasma contains antioxidants that protect the structural and functional integrity of the germ cell. these factors assure fertilization and embryo development. nevertheless, epigenetic alterations of the sperm such as altered chromatin packing, mistakes in imprinting, absence or alteration of the centrosome, telomeric shortening and absence of sperm rna, could affect functions leading to early embryo loss. conclusions: knowledge concerning sperm intervention previous to embryo development will provide the basis for better understanding and for possible diagnosis and treatment of diverse reproductive alterations in men that could impede embryo development.
?Qué saben los hombres del valle de Aburrá acerca de la salud reproductiva?
Ospina Medina,Luisa Fernanda; álvarez,ángela María; Cadavid,ángela Patricia; Cardona Maya,Wálter Darío;
Iatreia , 2012,
Abstract: objective: to evaluate the information and perceptions about reproductive health of a group of men in the aburra valley, antioquia, colombia. methods: 478 men aged between 10 and 58 years were surveyed by means of a form including 34 general questions on reproductive health. results: 58.6% of the surveyed men had initiated intercourse between the ages of 13 and 18 years; 97.9% had some knowledge on sexually transmitted diseases; 76% had not turned to a professional advisor before choosing a contraceptive method; 16.1% did not know which the function of an urologist is; 5% believed that varicocele only occurs in older men, and 22% did not know what a sperm analysis is. conclusion: results of this survey allow us to have a more accurate understanding of the behavior and knowledge of a group of men in antioquia, colombia about reproductive health. additionally, they highlight the need to take action involving men in basic aspects such as family planning, the desired number of children and protection against sexually transmitted infections.
Efecto de cinco extractos de plantas colombianas sobre espermatozoides humanos
Gallego,Ginet; Henao,Dubier; Ospina,Luisa; álvarez Gómez,ángela; Arango,Víctor; Cardona Maya,Walter; Cadavid,ángela;
Revista Cubana de Plantas Medicinales , 2012,
Abstract: introduction: the sperm capacitation test and the spermicidal activity or immobilization using plant extracts, allows for an increase in the current knowledge on the reproductive area. objectives: to evaluate the effect of five extracts from colombian plants bocconia frutescens, bomarea setaceas, muehlenbeckia platyclada, zanthoxylum lenticulare and piper subpedale on human spermatozoa. methods: human spermatozoa were incubated with each extract and their motility and viability were evaluated. additionally, sperm capacitation was evaluated using bovine serum albumin. results: after an initial assessment of the effect of plant extracts on human spermatozoa, the extracts from b. frutescens and b. setaceas were selected for capacitating tests since they did not change the sperm motility and viability. additionally, m. platyclada, z. lenticulare and p. subpedale extracts were selected for immobilization or spermicidal activities tests because they had had an effect on sperm progressive motility. conclusions: this study suggested three plants with promising spermicidal effect; in addition to the standardization of a biological system, allowing the assessment of the capacitation effect of some extracts over human spermatozoa.
Functional evaluation of sperm in colombian fertile men
Cardona Maya,Wálter Darío; Berdugo Gutiérrez,Jesús Alfredo; Ríos,Jesús de los; Cadavid Jaramillo,ángela Patricia;
Archivos Espa?oles de Urología (Ed. impresa) , 2007, DOI: 10.4321/S0004-06142007000700019
Abstract: objective: the aim of the present study was to evaluate in 111 ejaculates from fertile men membrane integrity of spermatozoa before selection and sperm motility, and sperm concentration and chromatin integrity before and after selection of motile spermatozoa. methods: we evaluated the membrane integrity (using hypoosmotic swelling test and eosin-y) before separation and chromatin integrity (using acridine orange), concentration and motility before and after separation by migration sedimentation technique. all individuals had pregnant wives or had procreated a baby during the last year. results: the data of sperm membrane integrity by the eosin-y and hypoosmotic swelling tests did not show signi ficant statistical differences and the correlation between them was low. the percentage of motile sperm (grades a + b) increased from 57% to 87% (p <0.001), the concentration decreased from 89 to 31 x 106 sperm/ml (p <0.001) and chromatin integrity increased significantly (p <0.0001) after separation of semen. conclusions: the great variation in the values obtained in the functional test in fertile males requires a re-evaluation of the use of these tests in clinical practice of infertility.
Evaluación de parámetros seminales no convencionales en individuos cuyas parejas presentan muerte embrionaria temprana recurrente: en busca de un valor de referencia
Rodríguez,Edisson; Gil-Villa,Aura María; Aguirre-Acevedo,Daniel Camilo; Cardona-Maya,Walter; Cadavid,ángela P;
Biomédica , 2011,
Abstract: introduction. previous studies related alterations in non-conventional seminal parameters with recurrent early embryonic death for one couple. a reference standard of clinical assessment is required for the management of these kinds of patients. objective. normal semen parameters were established based on functional tests including lipid peroxidation of sperm membranes, antioxidant capacity of seminal plasma and integrity of sperm chromatin to compare with men whose partners have recurrent early embryonic death. these parameters set reference values to identify subfertile individuals whose condition can be attributed to altered semen parameters. materials and methods. the conventional and non-conventional semen parameters of 47 samples of semen were evaluated. thirty-six samples were from subfertile individuals whose partners had a history of early recurrent embryo death, and 11 samples were from individuals with recent evidence of normal fertility. results. by discriminant analysis, the two groups were classified as follows: a value below 0.50 for 86.1% of individuals in the group of recurrent early embryonic death, and a value above 0.50 to classify 81.8% of individuals in the group of recent fertility. conclusions. this reference value of 0.5 based on the results of sperm tests can identify infertile male patients whose partners have a history of early embryonic death. this will aid the physician to suggest treatments more focused on the possible cause of subfertility.
Pregnancy outcome in women with antiphospholipid syndrome and alloimmunity: a case report
Casta?eda Ospina, Serguei Abel;Cardona Maya, Wálter Darío;Bueno Sánchez, Julio César;Cadavid Jaramillo, ángela Patricia;
Sao Paulo Medical Journal , 2003, DOI: 10.1590/S1516-31802003000600006
Abstract: context: patients with antiphospholipid syndrome and alloimmunity have poor pregnancy outcomes. several diagnostic and therapeutic options exist for these disorders, although there is no consensus as to the best treatment. case report: we present here the clinical course and treatment of a woman with a history of two miscarriages who joined our program 10 years ago and has been followed up ever since. after antiphospholipid syndrome and alloimmune failure were diagnosed, she was given preconceptional treatment using unfractionated heparin, aspirin, prednisone and lymphocyte immunizations. she delivered two premature babies in the following two pregnancies. at present both children are healthy and are attending school. the fifth pregnancy was unsuccessful, in spite of having undergone a similar but postconceptional therapeutic scheme. we discuss this case focusing on the pathogenic mechanisms and the therapeutic aspects of these disorders.
Lack of Association between Recurrent Pregnancy Loss and Inherited Thrombophilia in a Group of Colombian Patients
Henry Cardona,Serguei A. Casta eda,Wálter Cardona Maya,Leonor Alvarez,Joaquín Gómez,Jorge Gómez,José Torres,Luis Tobón,Gabriel Bedoya,ángela P. Cadavid
Thrombosis , 2012, DOI: 10.1155/2012/367823
Abstract: Studies have shown an association between recurrent pregnancy loss and inherited thrombophilia in Caucasian populations, but there is insufficient knowledge concerning triethnic populations such as the Colombian. The aim of this study was to evaluate whether inherited thrombophilia is associated with recurrent pregnancy loss. Methods. We conducted a case-control study of 93 patients with recurrent pregnancy loss (cases) and 206 healthy multiparous women (controls) in a Colombian subpopulation. Three single nucleotide polymorphisms (SNPs) markers of the inherited thrombophilias factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T were genotyped by PCR-RFLP. Activated protein C resistance and plasma levels of antithrombin, protein C, and protein S were also measured. Results. The frequency of thrombophilia-associated SNPs, activated protein C resistance, and anticoagulant protein deficiencies, was low overall, except for the methylenetetrahydrofolate reductase C677T SNP. The differences between patients and controls had no statistical significance. Conclusion. Our study confirms the low prevalence of inherited thrombophilias in non-Caucasian populations and it is unlikely that the tested thrombophilias play a role in the pathogenesis of recurrent pregnancy loss in this Colombian population.
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