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Search Results: 1 - 10 of 8751 matches for " ángela Gutiérrez "
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Esclerosis múltiple: evidencias y controversias
Gutiérrez-álvarez,ángela María;
Revista Ciencias de la Salud , 2006,
Abstract: introduction: multiple sclerosis is a chronic recurrent inflammatory disorder of the central nervous system. the pharmacological treatment of multiple sclerosis has been evaluated with multiple controlled clinical trials that allow the clinician to count with evidence based information to decide the more indicated treatment for each patient. methodology: a review of the scientific literature was conducted to clarify controversial issues in a clinical relevant topic. development: the diagnostic criteria and different treatments available are reviewed, in order to consider the clinical utility of the disease modifying agents such as the immunomodulatory treatments. the three used types of interferon are well tolerated and reduce in approximately a third the number of bouts in the remitent recurrent form; there is no significant difference between the three of them.
Multiple sclerosis: evidence and controversies
ángela María Gutiérrez-álvarez
Revista Ciencias de la Salud , 2006,
Abstract: Introduction: Multiple sclerosis is a chronicrecurrent inflammatory disorder of the centralnervous system. The pharmacological treatmentof multiple sclerosis has been evaluated withmultiple controlled clinical trials that allow theclinician to count with evidence based informationto decide the more indicated treatmentfor each patient.Methodology: A review of the scientific literaturewas conducted to clarify controversialissues in a clinical relevant topic.Development: The diagnostic criteria anddifferent treatments available are reviewed, inorder to consider the clinical utility of the disease modifying agents such as the immunomodulatorytreatments. The three used types ofinterferon are well tolerated and reduce in approximatelya third the number of bouts in theremitent recurrent form; there is no significantdifference between the three of them.
Neuromielitis óptica. Reporte de caso
Quintero Cusguen,Patricia; Gutiérrez álvarez,ángela María;
Revista Ciencias de la Salud , 2009,
Abstract: neuromyelitis optical, also known as devic’s syndrome, is a disease which combines optic neuritis and transverse myelitis. some years ago it was considered as a form of multiple sclerosis. actually, it is consider as a different disease, on the basis of the clinical, imaging, serology and immunopatholoy profile. a case of 29 years old female patient is reported, based on her clinical findings which began in the fifth postpartum month, with progressive lower limb paresis, associated with bilateral vision loss. this paper attempts giving a synoptic overview of this uncommon immune mediated demyelinating condition; it summarises the most important epidemiological parameters and presents the diagnostic and therapeutic possibilities available today.
Antidepresivos de nueva generación en neuropatía diabética dolorosa
ángela M. Gutiérrez-álvarez,Carlos B. Moreno
Revista Ciencias de la Salud , 2011,
Abstract: The incidence of diabetic neuropathy increases with the duration of diabetes and the degree of hyperglycaemia. Pain is one of the mostcommon and incapacitating symptoms of diabetic neuropathy and itspharmacological control is complex. The effectiveness of antidepressive agents has been described in different types ofneuropathic pain, but their effectiveness, when used as analgesics in painful diabetic neuropathy, still remains controversial. Objective: To review the possible role of new-generation antidepressive agents in the treatment of pain in diabetic peripheral neuropathy.This work has thus consisted of a meta-analysis for determining which antidepressive agent had the best analgesic potential in managing pain in patients suffering from painful diabetic neuropathy. Methods:This search covered the Cochrane, MEDLINE, EMBASE and LILACS databases, between January 2000 and August 2007. The followinginformation was obtained from each article: criteria for diagnosing diabetic neuropathy, patients’ age average, antidepressant drugreceived and dose, sample size, duration of the disease and treatmentfollow-up, outcome measurement, evaluation of pain and rescuemedication. Results: A combined RR: 1.67 (95% CI 1.38 – 2.02) wasobtained; this result indicated that the antidepressive agentduloxetine, was effective for controlling pain in diabeticneuropathy. The corresponding NNT for Duloxetine was established,according to our interests; NNT = 6 (95% CI 5- 8) for achievinggreater than 50% analgesia in patients suffering from painfuldiabetic neuropathy. Discussion: Antidepressive agents are frequently employed in the specific case of diabetic neuropathy; their analgesic benefit has been demonstrated.
Neuromyelitis Optica. Case Report
Patricia Quintero Cusguen,ángela María Gutiérrez álvarez
Revista Ciencias de la Salud , 2009,
Abstract: Neuromyelitis Optica, also known as Devic’sSyndrome, is a disease which combines opticneuritis and transverse myelitis. Some years ago it was considered as a form of multiple sclerosis.Actually, it is consider as a different disease, onthe basis of the clinical, imaging, serology andimmunopatholoy profile.A case of 29 years old female patient is reported,based on her clinical findings which beganin the fifth postpartum month, with progressivelower limb paresis, associated with bilateralvision loss.This paper attempts giving a synoptic overviewof this uncommon immune mediateddemyelinating condition; it summarises themost important epidemiological parameters andpresents the diagnostic and therapeutic possibilitiesavailable today.
Grown-out of seeds of the taquilla clam Mulinia edulis (King & Broderip, 1832) in the subtidal zone in northern Chile and in the intertidal zone in southern Chile Engorda de semillas de la almeja taquilla Mulinia edulis (King & Broderip, 1832) en la zona submareal en el norte y en la zona intermareal en el sur de Chile
Alejandro Abarca,Doris Oliva,Rodrigo Gutiérrez,ángela Celis
Latin american journal of aquatic research , 2012,
Abstract: Seeds of the clam Mulinia edulis produced in a hatchery were grown in bottom cages in the subtidal zone of Tongoy Bay (northern Chile) and in the intertidal zone of Chullec (Chiloé Island, southern Chile), to compare the growth and survival of small and large seeds of the same production in different environments and latitudes. Seeds were shipped twice to Chullec, once in summer and once in winter. Previous experiments with seed transportation (14.2 ± 2.4 mm) showed that they are able to survive more than 24 h out of water. The growth rate of both large and small seeds was greater in Tongoy than in Chullec, reaching maxima of 1.24 mm month-1 in the small seeds of Tongoy and 1.06 mm month-1 in the same group in Chullec. The growth rates obtained for M. edulis were similar to those described for other cultured clams. Seeds grown in Chullec presented a significantly greater weight by size than the seeds grown in Tongoy. Survival after 12 months was 38% and 88% in Tongoy and 19.4% and 37.3% in Chullec for small and large seeds, respectively. Seeds produced in hatcheries are able to withstand long travel (1,360 km) and grow in the intertidal zone of southern Chile, where the operation of the culture is simple and cheap. The growth curve presents an inflection point around 20 mm length, probably related to the age at sexual maturity. Growing out seeds in the intertidal zone in southern Chile is seen as a new activity for artisanal fishermen. Semillas de la almeja Mulinia edulis producidas en el Hatchery de Pesquera San José (Tongoy) fueron engordadas en sistemas de fondo en la zona submareal de bahía Tongoy e intermareal en Chullec (Chiloé), para comparar el crecimiento y la supervivencia de semillas pequenas y grandes de una misma producción en diferentes ambientes y latitudes. Se realizaron dos envíos de semillas a Chullec, uno en verano y otro en invierno. Experimentos de simulación del transporte de semillas (14,2 ± 2,4 mm) muestran que éstas sobreviven al transporte por más de 24 h. La tasa crecimiento de las semillas grandes y pequenas fue mayor en Tongoy que en Chullec, alcanzando un máximo de 1,24 mm mes-1 en las semillas chicas de Tongoy y de 1,06 mm mes-1 para el mismo grupo en Chullec. Las semillas engordadas en Chullec presentaron un peso significativamente mayor e igual talla que las de Tongoy. La supervivencia, después de 12 meses, de las semillas pequenas cultivadas en Tongoy fue de 38% y de 19,4% en Chullec y de las semillas grandes de 88% y 37,3% respectivamente. Las semillas producidas en hatchery son capaces de sobrevivir a largos traslados
LA APERTURA DE LOS CENTROS EDUCATIVOS A SU ENTORNO: LOS CENTROS DE EDUCACIóN SECUNDARIA
ángela Martín Gutiérrez,Juan Antonio Morales Lozano
Perspectiva Educacional Formación de Profesores , 2013,
Abstract: La sociedad actual plantea nuevos retos a las organizaciones educativas, sus demandas reflejan la necesidad de capacitar al alumnado para el mundo laboral, lo que plantea la importancia de participar, trabajar en equipo y colaborar juntamente. Así los Centros Educativos, sobre todo los que ofertan ense anzas secundarias, se plantean la necesidad de establecer relaciones de colaboración con el entorno. Debido a esta realidad, nuestro estudio persigue como objetivo dar a conocer las relaciones de colaboración que los centros de educación secundaria de Andalucía mantienen con el entorno. Para ello, se ha utilizado una metodología cuantitativa, que mediante el uso del cuestionario nos ayudó a contextualizar el problema de investigación. Los resultados reflejan que las relaciones más destacadas son las establecidas con otros centros educativos de la ciudad y con las instituciones locales, y dentro de las menos destacadas, se encuentran las relaciones establecidas con los sindicatos y agentes sociales.
Why and how to assess the quality of research in medicine?
ángela R. Gutiérrez Rojas,Rosa E. Jiménez Paneque
Revista Cubana de Cardiología y Cirugía Cardiovascular , 2011,
Abstract: Scientific research is recognized as the main mean resource of science to enrich its capital of knowledge about the surrounding natural and social reality.However, if this activity is not carried out with the required quality, dubious results will be obtained and with them the risk of introducing actions in socialpractice whose validity has not been utterly demonstrated. This is the main justification for the employment of methodological procedures guiding to carryout research with the quality that allows the introduction of results in practice with the essential security. The article approaches the reasons to promote thequality in research work and offers elements on how to appraise it through what is published in scientific journals
Factor reumatoide: asociación con la erosión radiológica y actividad de la artritis reumatoide Rheumatoid factor: association with the radiological erosion and with the rheumatoid arthritis activity
Elena Kokuina,Araceli Chico,Liuber Carballar,ángela Gutiérrez
Revista Cubana de Medicina , 2008,
Abstract: OBJETIVO: Definir la relación del factor reumatoide (FR) con la erosión articular radiológica, la actividad de la enfermedad y la discapacidad funcional de la artritis reumatoide (AR). MéTODOS: Se realizó un estudio transversal con 209 pacientes con AR establecida, de estos, 74 con AR de corta evolución (= 2 a os). Se evaluaron los indicadores siguientes: FR por aglutinación del látex (FR-A), FR por inmunoturbidimetría automatizada (FR-T), velocidad de eritrosedimentación (VSG), proteína C reactiva (PCR), índice de actividad de la enfermedad (Disease Activity Score 28, DAS28), índice de discapacidad funcional (Health Assessment Questionnaire score, HAQ) y la presencia de erosiones radiológicas. RESULTADOS: El 77 % de los pacientes positivos de FR-A y el 73 % de los positivos para el FR-T presentaron erosiones radiológicas, opuestamente al 38 % de los negativos para el FR-A (p<0,001) y al 14 % de los negativos para el FR-T (p<0,001). Las cifras medias del FR-A de los pacientes según los 4 grados de afectación articular (máximo: > 6 articulaciones erosionadas; mínimo: 0 erosión, < 6 articulaciones inflamadas) fueron de: 484; 162; 57 y 17 UI/mL (p<0,001); y las del FR-T de: 277; 185; 22 y 33 UI/mL (p<0,01). El valor predictivo positivo (VPP) para la erosión del FR-A >512 UI/mL fue de 92 % y el del FR-T >97 UI/mL fue de 96 %. Los valores medios del DAS28 en los pacientes positivos de FR-A y FR-T fueron de 5,04 y 4,94, respectivamente, mientras que, en los negativos fueron de 4,26 y 3,97 (p<0,001 para ambos); y los del HAQ de 1,31 y 1,29 en los positivos de FR-A y FR-T, respectivamente, mientras que en los negativos de 0,99 y 0,89 (p<0,01 para ambos). Se encontró correlación entre las cifras del FR por ambos métodos y las de VSG, PCR, DAS28 y HAQ (p<0,05 o p<0,01). CONCLUSIONES: Niveles altos del FR se corresponden con un grado mayor de inflamación y destrucción articular en la AR. OBJECTIVE: to define the relation of the rheumatoid factor with the radiological articular erosion, the activity of the disease and the functional disability of rheumatoid artritis (RA). MéTHODS: A cross-sectional study was conducted among 209 patients with RA. Of them, 74 with RA of short evolution (= 2 years). The following indicators were evaluated: RhF by latex agglutination (RhF-A), RhF by automated immunoturbidimetry (RhF-T), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), Disease Activity Score 28 (DAS 28), functional disability index (Health Assessment Questionnaire score, HAQ), and the presence of radiological erosions. RESULTS: 77 % of the RhF-A positive p
Determinación de la actividad celulolítica del suelo proveniente de cultivos de Stevia rebaudiana Bertoni
Gutiérrez R.,Viviana; Pinzón E.,ángela; Casas,Jaime; Martínez,María Mercedes;
Agronomía Colombiana , 2008,
Abstract: in this study celullolytic activity was determined in soil using a fluorogenic technique, which utilizes 4-methylumbelliferil b-glucose (muf) as substrate, and was compared with the quantitative technique of somogyi nelson (sn). sediment control was handled as a positive method of muf, as this technique was standardized previously in this matrix. soil sampling was done in puerto lópez, meta, in stevia rebaudiana bertoni crops using a simple random sampling. sediments were collected in la conejera wetland located in suba, bogotá. three treatments were done to both matrixes: t1: matrix (control); t2: matrix + crude enzymatic extract (2.34 uc); t3: matrix + streptomyces sp (59x103 spores/ml). to obtain the crude enzymatic extract used in t2 an isolation of the celulloytic microogranisms was done with greater activity in carboximethylcellulose (cmc 1%) from soil samples for its subsequent fermentation and extraction of enzyme extract. incubation of the matrix in three treatments was done at room temperature during 60 days where tests were performed every 15 days in order to analyze enzymatic activity by the established methods (muf and sn). humidity was maintained at 4.6%. no evidence of differential effects in the enzymatic activity with any of the treatments was found. also, there was no statistical correlation between the methods (<16%). thus, we propose the fluorogenic technique as a viable and reliable methodology to determinate cellulolytic activity because of its high specificity, faster assembly as well as its easy manipulation, precision and repeatability. nevertheless the sn technique has not been ruled out for future studies.
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