Publish in OALib Journal
APC: Only $99
To describe a traumatic brain injury patient who experienced profound dyskalemia
upon the initiation and cessation of a pentobarbital infusion and propose management
options for future patients receiving this intervention. Methods: Case report. Results:
Case report. Conclusions: Dyskalemia has become an anticipated side effect of high
dose barbiturate infusions in the setting of elevated intracranial pressure. Hypokalemia
during the administration of a barbiturate infusion has been identified within this
patient population and was an expected adverse event during this intervention. However,
in this case we observed a significant and complicated refractory hyperkalemia
upon cessation of the barbiturate infusion which required aggressive management.
An objective causality assessment suggests that this adverse event was possibly
related to pentobarbital. What this case documents that other cases have not is
that upon re-introduction of the pentobarbital infusion, serum potassium levels
did not normalize. This questions whether severe rebound hyperkalemia is a pharmacodynamic
or infusion-related reaction. More data is needed to identify the mechanism of this
adverse event and recommend an appropriate treatment approach.
The possibilities of upgrading some refractory properties of Alkaleri Clay (Alumino-silicates), found in Alkaleri Village, Bauchi State, Nigeria, by blending with tin tailings for the production of fireclay refractory bricks were investigated. Refractory properties such as: linear shrinkage, apparent porosity, bulk density, cold crushing strength and thermal shock resistance were tested with percentage additions of tin tailings from 5 - 30 wt% in the blend. The test was conducted using the standard test techniques in each case. The results were compared with standard refractory properties for fire clay bricks. Cold crushing strength, bulk density, refractoriness and thermal shock resistance of the bricks made from the blend clay increased, as the percentages of tin tailings increased. The Linear shrinkage and apparent porosity decreased as the percentages of tin tailings addition increased. All the values obtained from the blends are within the recommended values for dense fireclay bricks. Hence, dense fireclay can be produced from this blended.