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Search Results: 1 - 10 of 831 matches for " novel "
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The pathophysiology of AHF
—New insights from recent studies of novel diuretics and vascular modulating therapies

Gad Cotter, Olga Milo, Beth Davison
World Journal of Cardiovascular Diseases (WJCD) , 2013, DOI: 10.4236/wjcd.2013.31A020
Abstract: Treatment of chronic congestive heart failure (HF) has improved substantially during the past decades, with the introduction of modulators of the renin angiotensin aldosterone system (RAAS) such as angiotensin converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs) and aldosterone antagonists and the introduction of the lifesaving beta-blockers as well as device therapy. Despite the dramatic improvement in the treatment of chronic HF, no such progress was achieved in the treatment of acute heart failure (AHF). Diuretics that were never rigorously examined in well controlled large prospective randomized studies remain the cornerstone and almost exclusively the only intravenous therapeutic option for AHF and no further effective therapy as introduced in more than 30 years. As a result, the short term morbidity and most importantly mortality of AHF remains extremely high with up to 20% of patients dying in the first months after admission for AHF and an additional 20% being readmitted to the hospital. In the current manuscript we will address the practical concerns regarding established and novel diuretic and vascular modulating therapies in patients with AHF, examine their recommended use and seek to determine a path to developing better and more effective therapies for AHF.
Assoc. Prof. Dr. Mehmet NARLI
Turkish Studies , 2009,
Abstract: Some views (or propositions) on autobiography andnovel relation are set forth. Each proposition is tried toprove in its context in this article. The aim is to showthat the opinions that there exist opposite views in therelations between autobiography and novel and theseviews are appropriated as they are, are disputatious. Therelation between writer and writing is connection that iscreated by changing every other. So, it is not possible toclassify which one is autobiographical, one not.
An Exploration of Hausa Verbal Art Forms in Shaihu Umar: A Hausa Novel  [PDF]
Chaibou Elhadji Oumarou
Advances in Literary Study (ALS) , 2015, DOI: 10.4236/als.2015.31004
This paper explores the Hausa verbal art forms in Shaihu Umar, a novel first published in the Hausa language and then translated into English. The paper mostly focuses on the author’s use of the structures of a Hausa initiation tale as a vehicle for the narrative in the novel. In other words, the paper attempts to investigate how the author uses the structures of Hausa tales for stylistic effects. As a result, the paper tries to identify and analyze what the novel owes to the indigenous Hausa literary tradition as an illustration of the interface between orality and literacy.
Phylogenetic Analysis and Taste Cell Expression of Calpain 9 in Catfish (Ictalurus punctatus)  [PDF]
Tetsuya Ookura, Eiki Koyama, Anne Hansen, John H. Teeter, Yukio Kawamura, Joseph G. Brand
Natural Science (NS) , 2015, DOI: 10.4236/ns.2015.73016
Abstract: The calpains, calcium-activated neutral proteases, play important roles in calcium-regulated intra-cellular signal transduction cascades. Here we report the isolation and initial characterization of a cDNA encoding a calpain 9, digestive tract specific calpain, from catfish taste epithelium. This calpain 9 (Ip-CAPN9a) shares 61% identity with human calpain 9. Phylogenetic analysis provides evidence that catfish calpain 9 and the related enzymes from Oncorhynchus mykiss, Danio rerio, Xenopus laevis, Mus musculus, Rattus norvegicus and Homo sapiens make up a distinct clade within the tissue-specific calpain family. Northern blot analysis reveals that Ip-CAPN9a is predominantly expressed in barbell and digestive tract, but not expressed in brain. An antibody against the N-terminal segment of Ip-CAPN9a recognizes cells within the taste buds in catfish barbells.
Aspectos del ingenio y la industria en el Buscón de Quevedo
Revista signos , 2005, DOI: 10.4067/S0718-09342005000100008
Abstract: this article puts forward a review of the terms ?industria? and ?ingenio? in the spanish literary golden age, especially applied to the buscón of francisco de quevedo. the essay also offers examples of ?agudezas? and references of the picaresque ?industria? in quevedo?s novel
Assoc. Prof. Dr. Osman GüNDüZ
Turkish Studies , 2009,
Abstract: Novel and story, which we have become familiarwith, came from the western world starting from thesecond half of the nineteenth century as a form. Up tillthat time, Turkish society met its need of fiction with folkstory, mesnevi, fable, legend, etc., which were somewhat traditional types. Yet, the change was not easy. Turkishnovel, which underwent a period of slow development bythe Republican period, was affected considerably bytraditional narrative forms in style, technique ofstorytelling and plot. In this study focusing on thetransition from traditional narrative forms to modernnovel seks to follow the traces of this effect in the worldsof novels in the period with a focus on the developmentprocess of novel.
La anomia en las novelas de crímenes en Colombia
Forero Quintero,Gustavo;
Literatura y lingüística , 2011, DOI: 10.4067/S0716-58112011000200003
Abstract: this paper proposes an analysis of some colombian novels written between 1990 and 2005 based on anomie theory. from this sociological perspective, it defines the crime novel genre. thus, the author provides a brief account of what anomie is. secondly, he explains this concept in literature and, third, he applies it to contemporary colombian novels. finally, he proposes a characterization of the crime novel.
Selcuk Universitesi Sosyal Bilimler Enstitusu Dergisi , 2005,
Abstract: In this study, we tried to point out the reaction of the anti-novel against the traditionalnovel. The anti -novel oppose to the traditional forms of the classic roman which have attainedto its highest point with the Balzac’s novels. As it is known, the classic roman has a traditionbasing on strong basics. It exhibits a interesting and fascinating story around which turn a greatdeal of heroes whose characters, acts and feeling are deeply analysed This is because of theseromanesque elements that the anti novel rises up against the traditional roman. In this point it isquestion of a line which begins with La Princesse de Cleves of Madame de La Fayette and continuesuntil the works of the New Novelists.The anti novelist attempts to destroy the solid edifice of the traditional roman , to exposethe tricks and ruses of the novelist and do work of undermining the traditional roman by itsown proceedings. The anti novel puts in problematic the mimetic representation of the reality,the narration of story the narrative point of view , the position of the reader before the novelfictively created by the novelist and the situation of the character in the framework of the history
Discussion Article: Disciplinary Boundaries for Creativity  [PDF]
Stuart Rowlands
Creative Education (CE) , 2011, DOI: 10.4236/ce.2011.21007
Abstract: Creativity is a very topical issue and indeed a political one. For example, the very notion of ‘little c creativity’ seems to be a reflection of the requirements of what could be described as a ‘Post-Fordist’ economy. However, the call to develop creativity in education is largely based on the idea of creativity as the production of novel ideas. The central argument of this article is that creativity cannot be seen purely in terms of novel ideas but that it is intrinsically bound with the teaching of the academic disciplines. It is within the context of creativity in the sense of transforming the disciplines that two paradoxes are discussed. The first paradox is that the truly creative act is not the preserve of the genius but the potential for the whole of humanity. Secondly, creativity involves both thinking within the constraints of the discipline and challenging those constraints. This implies the need for students to engage in meta-discourse, involving the nature and history of the subject-matter taught.
Part 1: Synthesis and Evaluation of Novel Nano Scale Powdered Polyurethane Acrylate Binders  [PDF]
Mohamed M. El-Molla, Karima Haggag, Fatma N. El-Shall, N. O. Shaker
Advances in Chemical Engineering and Science (ACES) , 2012, DOI: 10.4236/aces.2012.22026
Abstract: Some new an aqueous polyurethane acrylate (waterborne binder) based on polyethylene glycol with different M. wt. mixed with polyol were carried out. Seven different polyurethane acrylate co-polymers were prepared aiming at substituting the two hydroxyl groups of polyethylene glycol (6000, 12,000 and 20,000 g/mol) and two primary hydroxyl groups of polyol through their reaction with corresponding calculated amounts of either isophorone diisoyanate or toluene diisocyanate and caped the remaining isocyanate group with either hydroxy ethyl acrylate or hydroxy propyl methacrylate to get on the polyurethane acrylate polymers [PUA]. From DSC measurement the result of Tg of synthesized PUA are in range from -8.78℃ to 36.4℃. So they can classify as soft binders. The infrared spectra, rheological properties, viscosity measurement, the weight average molecular weight, of the synthesize binders were investigated.
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