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Search Results: 1 - 10 of 79 matches for " fibromatosis "
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1 Case Clinical Report of Cranium Aggressive Fibromatosis and Literature Review  [PDF]
Qi Yan, Ming Li, Jintao Li
International Journal of Clinical Medicine (IJCM) , 2015, DOI: 10.4236/ijcm.2015.610098
Abstract: Objective: The purpose of this study is to explore the clinical characteristics and therapeutic methods of aggressive fibromatosis (AF) in skull. Methods: The clinical data and operative therapy of one case of aggressive fibromatosis in skull in our department were examined and reviewed. The associated literatures were reviewed and discussed. Results: It was indicated that the main manifestation of AF in skull was headache and skull tumor. There was prominent osteolytic destruction found in X-ray plain film for skull AF. And CT scanning showed that skull sclerotin was disorganized and inhomogeneous, with widen diploe. The skull fibromatosis constituted by fibroblasts and myofibroblas, which were mainly spindle-shaped without heteromorphism. Immunohistochemistry showed positive expression of β-catenin and Vim in these cells. The enlarged incision was adopted for the strategy of operation in this patient of skull AF. After follow-up, there was no recurrence of AF discovered. Conclusions: Skull AF is very rare in neurosurgical clinic. The clinical manifestation and iconography of AF were lack of specificity. Therefore, skull AF is hard to diagnose preoperatively. The effective diagnose is mainly dependant on histopathologic examination. As for treatment, operation is the most optimal method so far, which has a good therapeutic effect.
FIBROMATOSIS MANDIBULAR: PRESENTACION DE UN CASO
Valcárcel LLerandi,Julio; Fernández González,María del Carmen; Betancourt Nú?ez,Marisette;
Revista Habanera de Ciencias M??dicas , 2009,
Abstract: the fibromatosis constitutes some entities not very frequent pseudotumorals whose presentation in the maxillary one is exceptional. they are characterized by a great local aggressiveness with tendency to the recurrence and for none metastasize it can involve bone or the soft tissue. a 2 year-old masculine patient is presented that goes to consultation with increase of volume in region right mandible, of four months of evolution, accompanied by pain to the local pressure. radiography is observed wide area osteolysis at level of the body mandible that expands the cortical one, it loses weight it and in different areas it destroys it totally. he is carried out surgical treatment under it general anesthetizes. diagnosis, fibromatosis of the jaw. after five months you evolution has presented a satisfactory evolution without relapse
Sporadic Desmoid Tumor of the Small Bowel Mesentery in a Male Patient: A Case Report and Literature Review  [PDF]
Lamiae Amaadour, Zineb Benbrahim, Khadija Benhayoune, Layla Chbani, Samia Arifi, Nawfel Mellas
Journal of Cancer Therapy (JCT) , 2014, DOI: 10.4236/jct.2014.511104
Abstract: Aggressive fibromatosis arising from the small bowel mesentery is extremely rare. It may occur in association with previous trauma, abdominal surgery, drugs, Gardner’s syndrome, or familial adenomatous polyposis. This paper presents a 32-year-old man with no significant medical or surgical history, complaining of diffuse abdominal pain and discomfort. His computed tomography scan revealed a well-defined soft tissue mass in the peritoneal cavity. He underwent surgical excision of the mass with resection and anastomosis of the involved loop of the small intestine. Histological examination confirmed mesenteric fibromatosis without infiltration of the bowel. The patient remained well during the 8 months follow-up.
FIBROMATOSIS MANDIBULAR: PRESENTACION DE UN CASO MANDIBLE FIBROMATOSIS: A CASE PRESENTATION
Julio Valcárcel LLerandi,María del Carmen Fernández González,Marisette Betancourt Nú?ez
Revista Habanera de Ciencias M??dicas , 2009,
Abstract: La fibromatosis constituye una entidad pseudotumoral poco frecuente, cuya presentación en el maxilar es excepcional. Se caracteriza por una gran agresividad local con tendencia a la recurrencia y por no metastatizar. Puede involucrar hueso o el tejido blando. Se presenta un paciente masculino de 2 a os de edad, que acude a consulta con aumento de volumen en región mandibular derecha, de 4 meses de evolución, acompa ado de dolor a la presión local. Radiográficamente, se observa amplia zona osteolítica a nivel del cuerpo mandibular que expande la cortical, la adelgaza y en diferentes zonas la destruye totalmente. Se realiza tratamiento quirúrgico bajo anestesia general. El diagnóstico se correspondió con una fibromatosis de la mandíbula. Después de 5 meses se ha presentado una evolución satisfactoria sin recidiva The fibromatosis constitutes some entities not very frequent pseudotumorals whose presentation in the maxillary one is exceptional. They are characterized by a great local aggressiveness with tendency to the recurrence and for none metastasize it can involve bone or the soft tissue. A 2 year-old masculine patient is presented that goes to consultation with increase of volume in region right mandible, of four months of evolution, accompanied by pain to the local pressure. Radiography is observed wide area osteolysis at level of the body mandible that expands the cortical one, it loses weight it and in different areas it destroys it totally. He is carried out surgical treatment under it general anesthetizes. Diagnosis, Fibromatosis of the jaw. After five months you evolution has presented a satisfactory evolution without relapse
Current Perspectives on Desmoid Tumors: The Mayo Clinic Approach
Siddharth B. Joglekar,Peter S. Rose,Franklin Sim,Scott Okuno,Ivy Petersen
Cancers , 2011, DOI: 10.3390/cancers3033143
Abstract: Desmoid tumors are a rare group of locally aggressive, non malignant tumors of fibroblastic origin that can lead to significant morbidity due to local invasion. Despite advances in the understanding of these tumors, their natural history is incompletely understood and the optimal treatment is still a matter of debate. Local control is the main goal of treatment and there has been a change in philosophy regarding the management of these tumors from aggressive surgical resection to function preservation. A multidisciplinary approach is essential to plan local control with acceptable morbidity. The current Mayo Clinic algorithm for the treatment of these tumors is based on institutional experience and the available evidence in the literature: asymptomatic/non progressive lesions away from vital structures are managed with observation and regular imaging; primary or recurrent desmoid tumors which are symptomatic or progressive or near vital structures are managed with wide surgical resection when wide surgical margins are possible with minimal functional and cosmetic loss. When positive or close surgical margins are likely, surgical resection with adjuvant radiotherapy or definitive radiotherapy is preferred. If likely functional or cosmetic deficit is unacceptable, radiotherapy is the treatment of choice. Unresectable lesions are considered for radiotherapy, chemotherapy or newer modalities however an unresectable lesion associated with a painful, functionless, infected extremity is managed with an amputation.
Aggressive intraabdominal fibromatosis
?olovi? Radoje,Grubor Nikica,Radak Vladimir,Micev Marijan
Vojnosanitetski Pregled , 2006, DOI: 10.2298/vsp0609839c
Abstract: Background. Intraabdominal or mesenteric fibromatosis is a rare benign nonmetastatic neoplasm that appears as a sporadic lesion or in patients with familiar polyposis. Its evolution is unpredictable. About 10% of the cases show a very aggressive growth. Case report. We presented a 22-year-old woman in whom an aggressive intraabdominal fibromatosis had appeared during the first pregnancy as a well circumscribed ovoid tumor, involving the terminal ileum, the caecum, the ascending colon, the right kidney, the ureter, and the right common iliac artery. The tumor was excised with right colectomy, nephroureterectomy and resection of the involved artery using arterial reconstruction with graft interposition. Two years after the surgery the patient developed an inoperable tumor recurrence with a fatal outcome. Conclusion. In spite of a successful surgical excision during the original surgery intraabdominal or mesenteric fibromatosis might have an aggressive evolution leading to an inoperable tumor recurrency and a fatal outcome.
Análise quantitativa dos tecidos gengivais de ratos tratados com fenitoína e ciclosporina
SPOLIDORIO, Luís Carlos;GONZAGA, Heron Fernando de Souza;SPOLIDORIO, Denise M. P.;
Pesquisa Odontológica Brasileira , 2000, DOI: 10.1590/S1517-74912000000400004
Abstract: reactions to a number of idiopathic, pathological and pharmacological stimuli may result in overgrowth of gingiva, whose mechanisms have not been established yet. the aim of the present work was to evaluate morphometrically and stereologically the effect of phenytoin (pht) and cyclosporine (cs) on the gingival tissues of rats. ten rats received daily ip injection of pht, 2 mg/kg of body weight/day, which was increased in 2 mg at each two weeks, during 60 days. ten rats received 10 mg/kg of body weight/day of cs, subcutaneously, during the same period of the previous group. all rats treated with cs developed gingival overgrowth, with increased thickness of the epithelium, height and wideness of connective tissues, as well as, increased density of fibroblasts and collagen fibers, when compared with the rats treated with pht and with the control. these results suggest that cs, in the used dose, is more efficient in the development of gingival overgrowth in rats. cs-induced gingival overgrowth is a tissue with an altered composition, characterized by increasing of the density of fibroblasts and by physiologic unbalance of collagen synthesis.
Tumor desmoide abd?mino-pélvico
Valejo, Fernando Antonio Mour?o;Tiezzi, Daniel Guimar?es;Nai, Gisele Alborguetti;
Revista Brasileira de Ginecologia e Obstetrícia , 2009, DOI: 10.1590/S0100-72032009000100007
Abstract: desmoid tumor is a noncapsulated neoplasia, locally aggressive, originated from the fibroblasts of the musculo-aponeurotic tissues. even though with no malignant behavior, such as the ability of generating metastasis or of invasion, the desmoid tumor has a high tendency for local growth, causing deformities in the adjacent organs, pain and sometimes organ dysfunction, depending on the area involved. we report the case of a large intra-abdominal desmoid tumor, invading pelvic organs in a 53 year-old patient. the neoplasia has been totally extirpated and, at the moment, five years after the surgery, the patient presents no clinical or radiologic sign of lesion relapse.
Fibromatosis mesentérica: caso clínico-imagenológico y revisión bibliográfica
Whittle P,Carolina; Sánchez R,Lorena; Albarracin G,Juan; Hepp K,Juan;
Revista médica de Chile , 2006, DOI: 10.4067/S0034-98872006000100012
Abstract: we report a 42 years old female that presented with abdominal pain and no palpable mass. imaging abdominal ultrasound, cat scan and magnetic resonance showed a solid tumor located in the retroperitoneum. the patient was operated on excising the tumor. pathological examination of the surgical piece disclosed a retroperitoneal fibromatosis or desmoid tumor. postoperative evolution of the patient was uneventful and she was discharged 12 days after the surgical procedure
Juvenile hyaline fibromatosis and infantile systemic hyalinosis: Divergent expressions of the same genetic defect?
Dhingra Mandeep,Amladi Sangeeta,Savant Shankar,Nayak Chitra
Indian Journal of Dermatology, Venereology and Leprology , 2008,
Abstract: We describe here a three year-old girl with classic clinical and histological features of juvenile hyaline fibromatosis. We found a history of similar skin findings in her eldest sister, in whom the disorder took a rapidly progressive and fatal course in the second year of life, suggesting either a very severe form of juvenile hyaline fibromatosis, or the possibility of infantile systemic hyalinosis. The similarities and differences between these two described types of hyalinoses have been reviewed in reference to the present report.
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