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Search Results: 1 - 10 of 1173 matches for " eosinophilic meningitis [meningoencephalitis] "
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Molecular diagnosis of eosinophilic meningitis due to Angiostrongylus cantonensis (Nematoda: Metastrongyloidea) by polymerase chain reaction-DNA sequencing of cerebrospinal fluids of patients
Eamsobhana, Praphathip;Wanachiwanawin, Darawan;Dechkum, Naowarat;Parsartvit, Anchana;Yong, Hoi Sen;
Memórias do Instituto Oswaldo Cruz , 2013, DOI: 10.1590/S0074-02762013000100020
Abstract: cerebrospinal fluid (csf) samples from clinically diagnosed patients with detectable angiostrongylus canto-nensis-specific antibodies (n = 10), patients with clinically suspected cases that tested negative for a. cantonensis-an-tibodies (n = 5) and patients with cerebral gnathostomiasis (n = 2) and neurocysticercosis (n = 2) were examined by a single-step polymerase chain reaction (pcr) method using the ac primers for the 66-kda native protein gene. the pcr method detected a. cantonensis dna in csf samples from four of 10 serologically confirmed angiostrongyliasis cases. the pcr results were negative for the remaining csf samples. the nucleotide sequences of three positive csf-pcr samples shared 98.8-99.2% similarity with the reference sequence of a. cantonensis. these results indicate the potential application of this pcr assay with clinical csf samples for additional support in the confirmation of eosinophilic meningitis due to a. cantonensis.
Meningoencefalite na fase aguda do sarampo: relato de seis casos
EL-FAR, FABIANE;SZTAJNBOK, JAQUES;MAROTTO, PAULO C. F.;SEGURO, ANTONIO C.;
Arquivos de Neuro-Psiquiatria , 2000, DOI: 10.1590/S0004-282X2000000100020
Abstract: we present the clinical and laboratory manifestations of encephalitis following measles in six patients which were diagnosed during the epidemics that occurred in the city of s?o paulo, brazil, in 1997. we performed retrospective case analysis of the six patients diagnosed as having encephalitis due to measles. encephalitis was diagnosed based on clinical grounds and on the cerebrospinal fluid (csf) alterations. all the cases were serologically confirmed.of 467 patients with measles who presented themselves for medical care at the instituto de infectologia emílio ribas six were diagnosed with encephalitis. patient's age was 2 months to 28 years old. the most frequent symptoms were drowsiness and nuchal rigidity. csf showed an increased of white cell count in all cases. four patients were admitted to the intensive care unit. two of them required mechanical ventilation. in only two patients did the computerized tomography show abnormalities. all showed good recovery without sequelae.
Meningoencefalitis eosinofílica: Presentación y ense?anzas del primer caso de un brote
Sabina Molina,Domingo; Jam Morales,Blas; Nieto Cabrera,Raúl;
Revista Cubana de Medicina , 2007,
Abstract: the case of a 35-year-old male from "5 de septiembre" rural community, rodas, admitted in "dr. gustavo aldereguía lima" hospital due to persistent pulsatile headache, with ocular projection of 5 weeks of evolution, cutaneous hyperesthesia in occipital region, right lateral region of the neck, left dorsal region and right thigh, was presented. the physical examination only showed mild pain on flexing the neck. 11 % of eosinophilia was confirmed. csf of 950 leukocytes x mm3, with predominance of lymphocytes and 10 % of eosinophiles was found. the diagnosis of eosinophilic meningitis caused by angiostrongylus cantonensis was established. it was known that several work mates of the patient had similar symptoms and that there was alarm in the community. the case was studied with the presentation of an entity that is not considered in the daily practice, which made possible to clarify some cases whose origin was not very clear at the beginning.
Brote epidémico de meningoencefalitis eosinofílica en una comunidad rural
Sabina Molina,Domingo; Espinosa Brito,Alfredo; Nieto Cabrera,Raúl; Chávez Troya,Osmel; Romero Cabrera,ángel J.; Díaz Torralbas,Alina;
Revista Cubana de Medicina Tropical , 2009,
Abstract: introduction: the infection by nematode angiostrongylus cantonensis is the most frequent cause of eosinophilic meningoencephalitis. most of cases occur in isolation although numerous outbreaks have been described. objectives: to describe the clinical manifestations and the characteristics of the cerebrospinal fluid and other supplementary exams from 11 patients diagnosed as eosinophilic meningoencephalitis carriers. methods: a case study of eleven patients diagnosed with eosinophilic meningoencephalitis and admitted to "dr. gustavo aldereguía lima" general university hospital. these patients worked at the same workplace located in a rural area and their clinical symptoms appeared in the same period of time (january to february, 2006). results: predominant symptoms were persistent headache (100 % of cases 9, cutaneous paresthesia and hyperesthesia (100 %), myalgias (45 %), impaired vision (45 %), neck rigidity (18 %), peripheral facial paralysis in two cases (18 %). one single patient said that he had got fever. conclusions: meningoencephalitis caused by a. cantonensis should be suspected whenever a person suffers from persistent headache, paresthesias and hyperesthesias, even when neither fever nor neck rigidity is declared. eosinophilia in peripheral blood associated to previous symptoms may indicate such a diagnosis. pleocytosis, in which the percentage of eosinophils is high, is a characteristic of this disease; however, the lack of eosinophils in the cerebrospinal fluid does not reject this diagnosis. it is frequent that at some stage, lymphocytes will be predominant. the description of this case study allows us to present the first report of an outbreak of eosinophilic meningoencephalitis occurred in cuba.
Case series of eosinophilic meningoencephalitis from South India
Parameswaran K
Annals of Indian Academy of Neurology , 2006,
Abstract: Eosinophilic meningoencephalitis (EM) is a rare type of meningoencephalitis. The objective of this report is to describe a series of EM identified in a specific geographic area over a short period of time. Materials and Methods: This series of cases are described from a neurological center in Central Kerala occuring in the period between February 2004 and June 2006. Results: During this period we had identified ten patients (eight males and two females) with EM. Their mean age was 37.1 years (range 15-60 years). Main symptomatologies were fever, severe headache, body pain, abdominal pain and arthralgia. One patient was in akinetic rigid state with coma. All patients had peripheral eosinophilia. The cerebrospinal fluid (CSF) of all patients showed eosinophilic pleocytosis. The mean CSF white cell count was 588 cells. CSF differential count showed 50-70% eosinophils. CSF glucose levels were normal but proteins were markedly raised (mean CSF protein was 180 mg/dl). MRI brain showed T2 hyperintensities diffusely in periventricular white matter in the comatose patient. Contrast enhanced CT scan of the brain was normal in others. All eight male patients gave history of eating "raw flesh of Monitor Lizard" (Iguana) some three to fourteen days prior to the onset of symptoms. There was no such history for the female patients. Considering the history of exposure and eosinophilic meningitis we suspected a meningoencephalitis with Angiostrongylus cantonensis and treated them with albendazole, steroid and other supportive measures. All of them recovered. Conclusion: Eosinophilic meningitis (EM) is a rare condition and in this locality, a CNS infection with Agiostrongylus cantonensis is highly likely. AC is a parasite in monitor lizard. Human infection occurs from consumption of uncooked flesh or blood of infected lizards. Physicians need to maintain a high index of suspicion and enquire for any exposure to uncooked meat or blood of monitor lizard when faced with EM. Specific therapy with albendazole offers excellent response.
Toxocariasis of the central nervous system: with report of two cases
Moreira-Silva, Sandra F.;Rodrigues, Murilo G.;Pimenta, Jo?o L.;Gomes, Camila P.;Freire, Larissa H.;Pereira, Fausto E.L.;
Revista da Sociedade Brasileira de Medicina Tropical , 2004, DOI: 10.1590/S0037-86822004000200011
Abstract: clinical involvement of the nervous system in visceral larva migrans due to toxocara is rare, although in experimental animals the larvae frequently migrate to the brain. a review of the literature from the early 50's to date found 29 cases of brain involvement in toxocariasis. in 20 cases, various clinical and laboratory manifestations of eosinophilic meningitis, encephalitis, myelitis or radiculopathy were reported. we report two children with neurological manifestations, in which there was cerebrospinal fluid pleocytosis with marked eosinophilia and a positive serology for toxocara both in serum and csf. serology for schistosoma mansoni, cysticercus cellulosae, toxoplasma and cytomegalovirus were negative in csf, that was sterile in both cases. improvement of signs and symptoms after specific treatment (albendazole or thiabendazole) was observed in the two cases. a summary of data described in the 25 cases previously reported is presented and we conclude that in cases of encephalitis and myelitis with cerebrospinal fluid pleocytosis and eosinophilia, parasitic infection of the central nervous system should be suspected and serology should be performed to establish the correct diagnosis and treatment.
Toxocariasis of the central nervous system: with report of two cases
Moreira-Silva Sandra F.,Rodrigues Murilo G.,Pimenta Jo?o L.,Gomes Camila P.
Revista da Sociedade Brasileira de Medicina Tropical , 2004,
Abstract: Clinical involvement of the nervous system in visceral larva migrans due to Toxocara is rare, although in experimental animals the larvae frequently migrate to the brain. A review of the literature from the early 50's to date found 29 cases of brain involvement in toxocariasis. In 20 cases, various clinical and laboratory manifestations of eosinophilic meningitis, encephalitis, myelitis or radiculopathy were reported. We report two children with neurological manifestations, in which there was cerebrospinal fluid pleocytosis with marked eosinophilia and a positive serology for Toxocara both in serum and CSF. Serology for Schistosoma mansoni, Cysticercus cellulosae, Toxoplasma and cytomegalovirus were negative in CSF, that was sterile in both cases. Improvement of signs and symptoms after specific treatment (albendazole or thiabendazole) was observed in the two cases. A summary of data described in the 25 cases previously reported is presented and we conclude that in cases of encephalitis and myelitis with cerebrospinal fluid pleocytosis and eosinophilia, parasitic infection of the central nervous system should be suspected and serology should be performed to establish the correct diagnosis and treatment.
Polymerase chain reaction in the diagnosis of tuberculous meningitis: preliminary report
Machado, L.R.;Livramento, J.A.;Bydlowski, S.P.;Bendit, I.;Bravo, L.M.;Spina-fran?a, A.;
Arquivos de Neuro-Psiquiatria , 1994, DOI: 10.1590/S0004-282X1994000300029
Abstract: in this preliminary report the results of pcr for detection of dna sequences (65 kda antigen) of mycobacterium tuberculosis in csf samples from 20 patients are registered. in 10 patients there were clinical and laboratory findings suggesting the diagnosis of tuberculous meningitis (test group). in the other 10 patients, clinical and laboratory findings suggested meningitis or meningo-encephalitis from other etiologies (control group). in 7 patients from the test group antigenic dna sequences of mycobacterium tuberculosis were found in csf by pcr; positive results were not registered in the control group.
Aplicación retrospectiva del score para meningoencefalitis bacteriana en pacientes ingresados con síndrome neurológico infeccioso durante 5 a?os. Hospital Provincial Pediátrico Docente. Matanzas. 2001, 2003-2006
López Torres,Orlando; Montalván González,Guillermo; Martínez López,José A; Varela Terciado,Osvaldo; Berdayes Milián,Jorge D; Reina álvarez,David; Morejón Llanes,Luis O;
Revista M??dica Electr?3nica , 2011,
Abstract: in the clinical practice it is not always easy the differentiation between bacterial and aseptic meningoencephalitis, causing the raise of the treatment price in cases of aseptic meningoencephalitis, the increase of the potential risk of complications, and also a bigger familiar impact. we made a retrospective study of the patients admitted with the diagnosis of meningoencephalitis in the infantile hospital eliseo noel caama?o during a 5-years period (377 patients), applying them the bms (bacterial meningoencephalitis score). our objective was describing the score at patients' admittance, and classifying them as presenting high or low risk for bacterial meningoencephalitis, and also comparing the diagnoses at the admittance and discharge. as a result, 100 % of the patients with bacterial meningoencephalitis bacteriologically tested showed scores of 2 or higher (high risk); there were also identified 9 low risk patients (score 0 for bacterial meningoencephalitis), who were firstly considered as bacterial positive, and discharged as aseptic meningoencephalitis. the bacterial meningoencephalitis score could be a useful tool in the initial evaluation of the patients with the infectious neurological syndrome.
Características clínicas laboratoriais de 104 casos de meningoencefalite criptocócica
Darzé, Calil;Lucena, Rita;Gomes, Irênio;Melo, Ailton;
Revista da Sociedade Brasileira de Medicina Tropical , 2000, DOI: 10.1590/S0037-86822000000100003
Abstract: with the purpose of describing the clinical and laboratory characteristics of cryptococcus meningoencephalitis, we reviewed the records of 104 patients admitted with this diagnosis at couto maia hospital, reference for patients with infectious diseases in salvador-ba northeastern brazil, from 1972 to 1996. the patients' age varied from 8 months to 79 years. sixty-four (61.5%) patients were male. the duration of the disease varied from 2 to 150 days, average 27.7 days. the most common signs and symptoms were headache (92.7%), fever (84.4%) and neck stiffness (83.2%). the cell number in cerebrospinal fluid was greater than 4/mm? in 95.8% of the patients with lymphocyte predominance in 86.3% of the cases. the lethality rate was 42.7%.
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