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Search Results: 1 - 10 of 969 matches for " dialysis "
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Chest Radiography and Echocardiography Predictors of Early Hemodialysis Catheter Dysfunction  [PDF]
Kirsteen Burton, Jeremy O'Brien, Dheeraj Rajan
Open Journal of Radiology (OJRad) , 2012, DOI: 10.4236/ojrad.2012.23011
Abstract: Purpose: To determine whether radiographic heart morphology and echocardiography findings were associated with early central venous catheter (CVC) failure in hemodialysis patients. Materials & Methods: All hemodialysis catheter insertions between 1996-2007 were captured in a combined nephrology radiology database. Factors were identified that may be associated with early catheter failure. Factors examined included: echocardiography findings, radiographic evidence of flattened heart border, boot-shaped heart and left ventricular hypertrophy as well as patient comorbidities and peri-procedural characteristics. Results: Of the 132 CVC failures in 132 patients, 67 (50.8%) occurred within 30 days of insertion. Early CVC failure was more likely to occur in patients who had insertions from the left side (?2, p = 0.020) and with catheter tip position outside the cavoatrial junction (?2, p = 0.040). CVC failure rates also differed by year of placement (?2, p < 0.01), if the patient had evidence of left ventricular hypertrophy (?2, p = 0.030), left systolic dysfunction (?2, p = 0.030), and hypokinetic right wall mechanics (?2, p < 0.01). Conclusion: Radiographic findings of left ventricular hypertrophy and echocardiography findings of left systolic dysfunction were found to be associated with early failure.
Etiology of renal failure and peritoneal dialysis complications in Isfahan  [PDF]
Soheila Mojdeh, Shirin Karimi, Ali Mehrabi, Soheila Bakhtiari
Health (Health) , 2013, DOI: 10.4236/health.2013.510229

Introduction: Worldwide specific diseases are jeopardizing people’s health in the world as well as in Iran. Chronic renal failure as a developed and irreversible failure is usually progressive. End Stage Renal Disease (ESRD) is a situation when renal function is not sufficient to preserve one’s life leading to acute uremia resulting in dialysis and/or kidney transplantation for the patients. Although dialysis methods bring about complications for the patients, peritoneal dialysis is relatively cost-effective and more convenient to survive. The present study aimed to investigate (the) Etiologic factor of renal failure and imposed complications of peritoneal dialysis in the patients of Isfahan Alzahra hospital. Materials and Methods: It was a cross-sectional descriptive study conducted on 67 patients in Isfahan Peritoneal Dialysis Center. The data from the patients were collected through a two-section questionnaire whose first section was allocated to demographic information and the second part was related to the disease and complications of peritoneal dialysis. The collected data were analyzed by SPSS version 18. Results: The findings showed that there were 39 (58%) males and 28 (42%) females. Mean age of the subjects was 48 (18.8) years old. Regarding marital status, 65% were married and 35% were single. Considering complications, 28 subjects (53.5%) had infectious complications while 24 subjects (46.2%) had non-infectious complications. The highest frequency in etiologic factor of renal failure was diabetes mellitus in 29 subjects (43.9%) and the lowest for polycystic kidney in 2 subjects (3%); in addition, hypertension was observed in 51 subjects (77.3%). Discussion: The most frequent and important complication of peritoneal dialysis catheters is infection, whic

The Efficacy of Ferumoxytol in Peritoneal Dialysis Patients: A Short Scientific Report  [PDF]
Sayed Husain, Hani Judeh, Manaf Alroumoh, Farhana Yousaf, Prince Mohan, Ahla Husain, Chaim Charytan, Bruce Spinowitz
Open Journal of Nephrology (OJNeph) , 2014, DOI: 10.4236/ojneph.2014.42014

One of the major elements contributing to anemia in Chronic Kidney Disease (CKD) patients is iron deficiency. Iron supplementation in oral form is often not tolerated and ineffectively absorbed. Intravenous (IV) infusion is time consuming and is inconvenient in Peritoneal Dialysis (PD) patients self-treating at home. A new preparation of iron, ferumoxytol, is a carbohydrate-coated, paramagnetic iron oxide nanoparticle, which can be administered as a bolus intravenous injection, allowing the PD patient to more easily comply with current IV iron dosing regimens. Few studies have been done to evaluate the efficacy of ferumoxytol in PD population. We retrospectively reviewed the medical records of peritoneal dialysis patients who received at least one dose of ferumoxytol between January 2010 and August 2010 and observed that 17 patients showed an improvement in hemoglobin (Hb) to 1 gm/dl within a month of treatment along with a decrease in epoetin dosage in subsequent weeks.

The Incidence of Late-Onset Pompe Disease in Subjects with Obstructive Sleep Apnea: A Cross-Sectional Study  [PDF]
Jan Stolk, Nina L?n, Jeannette Gast-Strookman, Zoltan Lukacs, Paulina Nieves Cobos, Poul Jennum
Open Journal of Internal Medicine (OJIM) , 2014, DOI: 10.4236/ojim.2014.43010
Abstract: Objectives: Current treatment options for obstructive sleep apnea syndrome often work to the sa-tisfaction of the patient, but in certain cases may not yield the required results for reasons that remain unclear. Late-onset Pompe disease may be a contributing factor in these circumstances. The aim of the present study was to determine the incidence of late-onset Pompe disease in a population diagnosed with obstructive sleep apnea. Material and Methods: The study had a cross-sec- tional, explorative design to assess the prevalence of late-onset Pompe disease in subjects with an established diagnosis of obstructive sleep apnea syndrome. In two different study mid to large size sleep clinics in Europe patients have been asked to donate a blood sample for the detection of ac-id-glucosidase enzyme activity. Results: Of a total of 544 patients with mild to severe obstructive sleep apnea, none had an acid maltase deficiency. Conclusions: Screening for Pompe disease in newly or recently detected OSA patients in mid to large size sleep clinics is not clinically effective. It should be confined to those subjects with OSA when upright forced vital capacity during spirometry is only moderately abnormal, because of the disproportionate diaphragmatic involvement.
Evaluation of Peritoneal Dialysis Complications and Survival of Patients; A Single Center Study, Yazd ,Iran
M Rahimian,M Karimi,MH Lotfi,N Noori majelan
Journal of Shahid Sadoughi University of Medical Sciences , 2008,
Abstract: Introduction: Peritoneal dialysis is an established form of renal replacement therapy used in many patients with end – stage renal disease . Peritoneal dialysis has different complications This study was conducted in order to evaluate its complications and different survival probabilities of factors in Shahid Rahnemoon hospital . Methods: In this retrospective, historical cohort study, reports of 161 patients on peritoneal dialysis (Shaheed Rahnemoon hospital, dialysis department) from 3.Dec.1997 to 20.May.2007 were evaluated. Required data was gathered and analyzed by specific statistical tests. Results: The mean age of patients was 49.37 years (2 to 88 years) and most of them (41.6%) included in 40-59 years age group category. Peritonitis, exit site infection and catheter malposition was seen in 41.6% , 6.8% and 9.3% of patients ,respectively.Rate of peritonitis in females was more than males (p=0.002). Diabetes mellitus had no effect on death rate, but hypertension had a protective role. Conclusion: Peritonitis ,exit site infection and catheter malposition is more prevalent in females, but mortality rate is significantly higher in males.
Carnitine Deficiency and Improvement of Muscle Cramp by Administration of Carnitine in Patients with Liver Cirrhosis  [PDF]
Naoki Hotta
Open Journal of Gastroenterology (OJGas) , 2014, DOI: 10.4236/ojgas.2014.45036

Aim: We measured carnitine levels in patients with carnitine including dialysis patients, and examined whether administration of L-carnitine improved muscle symptoms. Methods: We measured carnitine levels in 27 patients with liver cirrhosis who were receiving treatment in our hospital, and administered L-carnitine (600 mg - 1800 mg) to patients having muscle cramps for approximately one month and examined the presence/absence of the symptom. We measured carnitine concentration before and after dialysis, before dialysis after the administration to eight dialysis patients, before and after the administration to 19 nondialytic patients. Results: The total carnitine levels before the dialysis of dialysis patients were an average of 42.2 μmol/L and fell to 17.7 μmol/L after more dialysis, but it was increased to 155 μmol/L after the administration of L-carnitine. In the nondialytic patients, the total carnitine levels were significantly increased from 71.7 μmol/L to 101.7 μmol/L after the administration of L-carnitine (P = 0.038). For symptomatic patients, significant improvement of muscle clamps was observed in the L-carnitine administrated group when compared with the non-administrated group (P = 0.0002). Conclusions: Total carnitine levels were low even before dialysis in the dialysis patients with liver cirrhosis in particular and they further decreased after the dialysis. Administration of L-carnitine increased the total carnitine levels and improved the symptom. Based on these results, we conclude that L-carnitine is useful for carnitine deficiency in patients with liver cirrhosis.


Impact of Dialysis Modality on Kidney Transplantation Outcomes  [PDF]
Imed Helal, Imen Gorsane, Fethi Ben Hamida, Adel Kheder
Journal of Biomedical Science and Engineering (JBiSE) , 2015, DOI: 10.4236/jbise.2015.82007
Abstract: Survival benefits of renal transplantation over dialysis therapy are well established for patients with end-stage renal disease (ESRD). Transition from one treatment modality to another is common. Understanding the differences in outcomes with the various renal replacement therapies will help nephrologists to provide best advice for dialysis patients. The influence of pretransplant dialysis modality on post-transplant outcomes is not clear. An overview of the various issues related to dialysis modality on kidney transplantation outcomes is discussed in this topic review. These include allograft and recipient survival, the impact of dialysis vintage and choice of dialysis modality on transplant outcomes.
Quality of Life of Patients on Peritoneal Dialysis in Dakar: A Senegalese Single Centre Experience  [PDF]
Kane Yaya, Cisse Mouhamadou Moustapha, Seck Sidy Mohamed, Lemrabott Ahmed Tall, Faye Maria, Hounsounou Christian, Diallo Kalilou, Ka El Hadji Fary, Niang Abdou, Diouf Boucar
Open Journal of Nephrology (OJNeph) , 2016, DOI: 10.4236/ojneph.2016.62005
Abstract: Introduction: Measuring the quality of life (QOL) in recent years has become an indispensable tool in monitoring patients suffering from chronic diseases. We conducted this study to assess QOL of patients undergoing peritoneal dialysis in Dakar, and to identify associated factors. Patients and Methods: This is a cross-sectional study which was carried out from 10 to 30 June, 2011 in the peritoneal dialysis unit at university hospital in Dakar. We included all patients with end-stage renal disease (ESRD) of any age, who were on PD since at least six months and who gave their consent. The QOL was assessed using the Kidney Disease Quality of Life Short-Form 1.2 (KDQoL-SF). Results: Sixteen patients were included with a mean age of 50.25 ± 13.48 years and a sex-ratio of 1.27. Considering SF-36, the overall mean score (SMG) was 60.11 ± 15.96 with a Mean Physical Component Summary Scale of 53.66 ± 16.98 and a Mental Component Summary Scale of 70.85 ± 6.14. Concerning the KDQoL-SF, the global mean score was 61.83 ± 19.35 with a mean physical score of 50.55 ± 16.52 and a mean mental score of 62.52 ± 21.53. The mean dialysis specific dimension score was 62.52 ± 21.53 and the mean mental health score was 85.93 ± 12.06. Age, weight, level of instruction and social support were correlated with a worse QOL. Conclusion: This study showed an alteration of our PD patients’ QOL, particularly in their physical health. However, the number of patients included in the study is not enough to permit a formal conclusion.
Evaluación longitudinal de la capacidad de transporte del peritoneo en diálisis peritoneal pediátrica
Lillo D.,Ana María; Azócar P.,Marta; Delucchi B.,Angela; Mazuela M.,Nelly; Cano Sch,Francisco;
Revista chilena de pediatría , 2000, DOI: 10.4067/S0370-41062000000200005
Abstract: the paedriatric patient treated with peritoneal dialysis must be periodically controlled in order to evaluate the adequacy of dialysis. objective: to evaluate the change in the dialysis parameters in uraemic paedriatric patients under chronic peritoneal dialysis. 24 patients attending the nephrology unit in the luis calvo mackenna hospital, university of chile, who entered the chronic peritoneal dialysis programme between january 1995 and october 1999 were enrolled. peritoneal and residual dialysis dose (ktiv) were measured at 3, 6 and 12 months after starting dialysis as well as the peritoneal equilíbrium test. growth was measured using the z point height/age at the beginning of dialysis and after 12 months. results: average kt/v peritoneal and residual dose was 1.77 (sd 1.05) and 1.04 (sd 0.64) at the beginning and 2.34 (sd 0.89) and 0.35 (sd 0.37) at 12 months respectively. the change in kt/v residual being significant (p < 0.05). the peritoneal equilibrium test for glucose and creatinine at 4 hours was 0.72 (sd 0. 16) and 0.31 (sd 0. 12) at the beginning, and at 12 months 0.73 (sd 0.20) and 0.40 (sd 0. 19) (p = ns). growth expressed as the z point changed from -1.86 (sd 1.06) to -2.05 (sd 0.90) at 12 months. in patients who were dialyzed before the age of 12 months the initial z point in comparison to 1 year later was -2.5 and -1.65 respectively. conclusions: the results show the stability of the peritoneal membrane during the study period, a progressive loss of stature during treatment and a positive growth in the group starting dialysis before the age of 12 months
Diálise peritoneal (DP) como tratamento da insuficiência cardíaca congestiva (ICC) em pacientes com doen?a renal cr?nica estágio IV
Prompt, Carlos Alberto;Almeida, Rafael de;Clausel, Nadine;Biolo, Andréa;Bercht, Fábio;Oliveira, Jer?nimo D. C.;Almeida, Eduardo D.;Pribbernow, Suzane;
Jornal Brasileiro de Nefrologia , 2009, DOI: 10.1590/S0101-28002009000300008
Abstract: congestive heart failure (chf) has a growing incidence, a great impact on public health, and high morbidity and mortality. excessive blood volume is a prevalent complication present in 80% of the patients diagnosed with chf. pharmacological and non-pharmacological strategies in the treatment of chf aim to better manage blood volume and reduce the use of diuretics. extracorporeal ultrafiltration has evidenced better weight control, and a reduction in the length of hospitalization and re-hospitalization of patients with chf. we report the cases of 2 patients diagnosed with chf and treated with peritoneal dialysis at hospital de clínicas de porto alegre.
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