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Search Results: 1 - 10 of 7935 matches for " diabetes mellitus "
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External validation of Indian diabetes risk score in a rural community of central India  [PDF]
Bharati Taksande, Minal Ambade, Rajnish Joshi
Journal of Diabetes Mellitus (JDM) , 2012, DOI: 10.4236/jdm.2012.21017
Abstract: Aim: To find whether the individuals of 45 years and more of rural area who are in higher tertile of Indian Diabetes Risk Score i.e. of IDRS of >60 as compared to those who are in lower tertile i.e. of <30, have high frequency of hyperglycemia, impaired glucose tolerance, and manifest diabetes mellitus. Methods: A cross-sectional community based study. The study was conducted in three pre-identified villages. For all consenting and the eligible subjects, the medical student visited their house and the fasting capillary blood glucose was done by One touch blood glucose monitoring system. Four simple questions and one anthropometric measurement for waist circumference helped in deriving the information for Indian Diabetes Risk Score from the same subject. Results: The Indian Diabetes Risk Score (IDRS) (consisting of the factors like age, abdominal obesity, physical inactivity and the family history) which predicted diabetes mellitus in the subject, its sensitivity was 97.50% and specificity of 87.89% when the score of >/+ 60 was externally validated on our rural population. Conclusion: Our study demonstrated that the Indian Diabetes Risk Score (IDRS) can be reliably applied as effective tool for the mass screening of diabetes in the community.
Implantaciones de Protamina-Zinc-Insulina en diabéticos infantiles y juveniles
Revista chilena de pediatría , 1951,
Características clínicas de la diabetes mellitus en un área de salud
Rebeca S González Fernández,Nelson Crespo Valdés,Nelson Crespo Mojena
Revista Cubana de Medicina General Integral , 2000,
Abstract: Se estudiaron 97 pacientes diabéticos pertenecientes al área de salud del "Policlínico Federico Capdevila" en el período de diciembre de 1996 a diciembre de 1997. La edad de debut más frecuente fue entre 45 y 59 a os (43,3 %) y la duración clínica mayor de 15 a os (38,2 %). Predominó la diabetes tipo 2 con obesidad (5,7 %) y en el sexo femenino (68,8 %). El tratamiento más utilizado fue la glibenclamida (42,3 %). Entre las enfermedades asociadas más frecuentes se encontró la hipertensión arterial (54,6 %), las enfermedades cardiovasculares (22,7 %) y los accidentes vasculares encefálicos (4,1 %). El 26,8 % presentó retinopatía y el 2,1 % insuficiencia renal crónica. Sólo 2 pacientes presentaron ceguera relacionada con su mal control metabólico, y no se encontró ningún amputado. La educación diabetológica fue deficiente expresada en que el 64 % no acudió a ningún curso de diabetes y el 50,5 % no se realizaban Benedicts. A study was undertook on 97 diabetes patients (December 1996 - December 1997) from the health area of the Capdevila policlinics. The more frequent debut age was from 45 to 59 years old (43.3 %) and clinical duration was longer than 15 years (38.2 %). There was a prevalence of type 2 diabetes with obesity (5.7 %) and of female sex (68.8 %). The most widely used treatment was with glibenclamide (42.3 %). Among the most frequent associated diseases we found arterial hypertension (54.6 %), cardiovascular diseases (22.7 %) and vascular encephalic accidents (4.1 %). The 26.8 % of the cases presented retinopathy and the 2.1 % chronic renal failure. Only 2 patients presented deficient metabolism control-associated blindness and there was no amputated patient. Diabetes education was deficient: 64 % of the patients received no diabetes courses and 50.5 did not make Benedicts.
Incidencia de la diabetes mellitus en un municipio de Ciudad de La Habana
Alberto Quirantes Hernández,Leonel López Granja,Jorge E Rodríguez Govea
Revista Cubana de Medicina General Integral , 1996,
Abstract: Se investiga la incidencia anual de la diabetes mellitus en el municipio Cerro de Ciudad de La Habana. La investigación comprende desde 1982 hasta 1991 y se tomó como fuente de información los datos de las Oficinas del Registro de Consumidores (OFICODAS). En los primeros 5 a os investigados se encuentra una tasa por 100 000 habitantes que va aumentando de forma progresiva. En el segundo lustro, varía esta tendencia, y se presenta una disminución en el primero y último a os de esta etapa, de ahí se derivan las posibles razones de esta variación. La tasa del primer a o analizado fue de 126,9 y la del último, de 201 diabéticos. La tasa máxima fue encontrada en 1986, con una cifra de 234,5. The annual incidence of diabetes mellitus in Cerro municipality, Havana City, is investigated. The investigation comprehends the period 1982-1991 and data from the Consumers Registration Offices are taken as an information source. During the first five years it is found a rate per 100 000 inhabitants that increases progressively.This trend changes during the second lustrum and there is a decrease in the first and last years of this stage, which is the posible cause of this variation. The rate of the first year analyzed was of 126,9 and that of the last one was of 201 diabetics. The highest rate was found in 1986 with 234,5.
The undisclosed role of anoxia/hypoxia and disturbed sleep on glucose metabolism  [PDF]
Patrizio Tatti, Desiderio Passali, Luisa Passali
Journal of Diabetes Mellitus (JDM) , 2012, DOI: 10.4236/jdm.2012.22029
Abstract: Up to recently the respiratory disturbances were considered a risk factor for hypertension, but there was no trace of a role in metabolic disorders. Only recently the existence of a connection among the respiratory disturbance caused by the obstruction of the upper airways and a wide array of metabolic disturbances has been demonstrated. The respective roles of anoxia/ hypoxia and the attendant disturbed sleep remain, however, to be clarified.
Comorbidity of Depression and Diabetes: In a Nutshell  [PDF]
Anisha Heeramun-Aubeeluck, Zheng Lu, Yanli Luo
Psychology (PSYCH) , 2012, DOI: 10.4236/psych.2012.329119
Abstract: Depression and diabetes mellitus (DM) have existed since ages. Yet, the etiologies of both diseases are unclear till date. However, the effects resulting from these diseases are well documented. Comorbidity of both disorders leads to increase disability and mortality rates. Besides presenting the epidemiological status of depression in DM, this review aims to highlight the different hypotheses governing the association of depression in DM and summarize the current trend in detection and management of depression. A high index of suspicion is required to detect depression in diabetic patients. There seems to be higher prevalence of depression in type 2 diabetes than in type 1 diabetes. Treatment should be tailored as per the individual needs and presence of comorbidity. Though there is no gold standard treatment for depressive diabetics, combinations of both pharmacological and non-pharmacological interventions are likely to improve outcomes. Selective serotonin reuptake inhibitors (SSRIs) and selective norepinephrine reuptake inhibitors (SNRIs) are preferred to conventional antidepressants. Collaborative care, psychoeducation and behavioral interventions are helpful in motivating patients to maintain treatment and improve psychological well-being and quality of life. Untreated depression in diabetics is costly to the health care and economic system as there is an increase in functional impairment and mortality rate. More efforts need to be made to effectively screen, diagnose and treat patients with comorbidity of diabetes and depression.
Effect of Peripheral Arterial Disease on Serum Ischemia-Modified Albumin Levels in Type 2 Diabetic Patients  [PDF]
Tugra Gencpinar, Umut Ayo?lu, Koray Aykut, Gokhan Albayrak, Hamid Ya?ar Ellidag, Muzaffer Y?lmaz, Kadir Sa?d??, Mustafa Emmiler
World Journal of Cardiovascular Surgery (WJCS) , 2014, DOI: 10.4236/wjcs.2014.45013
Abstract: Background: The aim of this study is to evaluate the role of IMA and the effect of Type-2 diabetes in peripheral arterial ischemic patient. Methods: In our study, randomized patient groups to be undergone peripheral surgery, consisting of 16 diabetic and 12 non-diabetic patients diagnosed with peripheral arterial disease, have been examined. After standard anesthesia, the surgery was performed by the same surgical team, blood samples were taken before and after cross-clamp, and the levels of ischemia modified albumin (IMA), which is a new ischemic marker, were studied spectrophotometrically. Demographic data were compared with the type-2 diabetes association. Results: In this study, we found that there were no correlation with the ankle brachial index (ABI) and risk factors of diabetes between postoperative IMA levels (P: 0.47). Preoperative IMA serum blood levels were significantly higher in patients with peripheral arterial disease (P: 0.70), and positively associated with ABI (diabetic group P: 0.04, non-diabetic group P: 00). Also, no correlation was found with X clamp times, ABI, and IMA blood levels (P: 0.30). In diabetic group, ischemia marker increase was high and there was a positive correlation between HbA1c levels (P: 0.002). Conclusion: Our study suggested that, preoperative serum IMA levels were positively associated with ABI. In diabetic group, the increase in IMA levels was high and there was positive correlation between HbA1c levels. IMA was a benefit marker for monitoring and early diagnosis of the peripheral arterial disease.
The Impact of a Community Pharmacy-Based Coaching Program on Patient Confidence and Lifestyle  [PDF]
Feng Chang, Nishi S. Gupta, Laura Smith, Dan Stringer
Open Journal of Preventive Medicine (OJPM) , 2014, DOI: 10.4236/ojpm.2014.46058

Objective: Like their urban counterparts, rural populations are experiencing increased health risks due to chronic disease. However, disease management is more problematic due to isolation, increased difficulty in getting to medical appointments, and reduced numbers of medical personnel. We undertook a pilot study to investigate the feasibility and utility of health coaching for rural residents with type 2 diabetes mellitus (DM2) from a local pharmacy. Methods: Using the pharmacy database to identify qualified individuals, a nursing student recruited four individuals aged 40 - 79, with a history of DM2 of 3 - 15 years, to participate in the pilot project. Individual in-person interviews were conducted to identify specific goals to effectively self-manage their condition and to rate their confidence in their ability to fulfill these goals. Three monthly sessions were held to review and update goals, and to record blood pressure, waist circumference and weight measurements. Results: At the end of the study, all four achieved success in reaching and maintaining their personal dietary and physical activity goals. Significantly, all participants expressed increased confidence in their ability to self-manage their diabetes after health coaching. Conclusion: The provision of health coaching services from local pharmacies has potential to support rural clients in chronic disease management in medically under-serviced rural areas.

Primary Tuberculosis of Tonsil in a Diabetic Patient—A Case Report  [PDF]
Nagula Parusharam, Kamreddy Ashok Reddy, Lokesh Rao Magar, Jadi Lingaiah
International Journal of Otolaryngology and Head & Neck Surgery (IJOHNS) , 2015, DOI: 10.4236/ijohns.2015.43032
Abstract: Though Tuberculosis is one of the most common causes of ill health and death worldwide, people with diabetes have 2 - 3 times higher risk of tuberculosis when compared with people without diabetes. Though tuberculosis can affect any part of the body, oral and oropharyngeal tuberculosis is rare, but reported. And it’s association with diabetes mellitus because of the decreased host mechanism, is still rare, but reported. A 50-year-old female diabetic who was on insulin therapy came to OPD of MGM hospital, Kakatiya Medical College, Warangal with complaints of severe pain in throat for the last 6 months. On examination, right tonsil was enlarged with granular surface. Left tonsil and rest of the oropharynx were normal. Examination of chest was normal and there was no evidence of pulmonary tuberculosis. Punch biopsy revealed tuberculosis of tonsil. Isolated cases of primary tuberculosis of tonsil without evidence of pulmonary tuberculosis are rare. Presence of diabetes mellitus makes patients 2 - 3 times more vulnerable for tubercular infection.
The Effectiveness of Glyburide Compared to Insulin in the Management of Gestational Diabetes Mellitus: A Systematic Review  [PDF]
Jephthah O. Odiba, Mzwandile A. Mabhala
Journal of Diabetes Mellitus (JDM) , 2015, DOI: 10.4236/jdm.2015.52007
Abstract: Background: Insulin therapy has been the mainstay in managing women with gestational diabetes mellitus (GDM), but some disadvantages of insulin have led to the use of glyburide, which is inexpensive in some countries, to manage GDM. However, there has been debate over its effectiveness, efficacy and safety when compared to insulin for maternal glycaemic control, and some adverse neonatal outcomes in GDM. Method: A systematic review of eight randomised controlled trial (RCT) studies was undertaken to compare glyburide and insulin. Studies involving 849 participants were included in the quantitative analysis. Results: There was no significant difference between glyburide and insulin in maternal fasting (P = 0.09; SMD: 0.13; 95% CI: 0.02 to 0.28) and postprandial (P = 0.45; SMD: 0.05; 95% CI: 0.09 to 0.19) glycaemic control and glycosylated hae-moglobin (P = 0.35; SMD: 0.08; 95% CI: 0.08 to 0.24). When compared with insulin, glyburide had an increase risk ratio (RR) for neonatal hypoglycaemia (P = 0.0002; RR: 2.27; 95% CI: 1.47 to 3.51) and large for gestational age babies (P = 0.03; RR: 1.60; 95% CI: 1.06 to 2.41). Estimation of standard mean difference shows that neonatal birth weight was significantly higher in subjects receiving glyburide than in the insulin group (P = 0.002; SMD: 0.21; 95% CI: 0.08 to 0.35). Conclusions: Glyburide was seen to be clinically effective and a safer alternative to insulin for maternal glycaemic control in GDM women. It is affordable, convenient and requires no comprehensive educative training at the time of initiation of therapy. However, its adverse outcomes—neonatal hypogly-caemia, high neonatal birth weight and large for gestational age babies—call for careful monitoring of GDM patients for any need for supplemental insulin.
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