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Search Results: 1 - 10 of 248 matches for " cytologic grading "
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Significance of nuclear morphometry in cytological aspirates of breast masses
Kalhan Shivani,Dubey Suparna,Sharma Sonia,Dudani Sharmila
Journal of Cytology , 2010,
Abstract: Background : Breast carcinoma is the most common malignancy globally. Cytological evaluation in breast lesions is largely subjective. Gradual progression of cells from normal to invasive involves nuclear changes that need to be viewed objectively. Aims : This study aims to apply nuclear morphometry on cytological breast aspirates. It evaluates its utility in differentiating benign vs. malignant lesions and correlates it with cytologic grading in malignant cases. Setting and Design : Nuclear morphometric parameters of malignant and benign cases were compared. Parameters of malignant cases were correlated with cytologic grading. Materials and Methods : Cytology was used to categorize aspirates from breast lumps into malignant (53 cases) and benign (29 cases). One hundred cells per case in both groups were mapped on DEBEL Cytoscan and six geometrical and three textural parameters obtained were compared. In malignant cases, morphometry was correlated with Robinson′s cytologic grading, which was further correlated in tissue sections (45 cases) with modified Scarff-Bloom-Richardson histologic grading. Statistical Analysis : Students "t"-test was applied for comparison between benign and malignant cases. One-way ANOVA followed by Bonferroni′s post hoc comparison was applied to compare the three cytologic grades. Results were considered significant when P<0.05. Results : Nuclear morphometry successfully differentiated between benign and malignant aspirates and correlated significantly with cytologic grades. Morphometry was especially useful in the diagnosis of atypical ductal hyperplasia and ductal carcinoma in situ. Useful parameters were mean nuclear area, long axis, short axis and total run length. Cytohistologic correlation was 83.3%, 88.9% and 88.9% for cytological grades 1, 2 and 3 respectively. Conclusions : Nuclear morphometry was thus a useful objective tool in the evaluation of breast masses.
Pass/Fail and Discretionary Grading: A Snapshot of Their Influences on Learning  [PDF]
Sherri Melrose
Open Journal of Nursing (OJN) , 2017, DOI: 10.4236/ojn.2017.72016
Abstract: This article provides a snapshot of pass/fail and discretionary grading approaches, highlighting the advantages and disadvantages of each. Norm-referenced and criterion-referenced grading practices and their associations with learning are identified. A brief historical backdrop illustrates how grading practices have evolved. The inherent subjectivity of grading is emphasized. Pass/fail grading supports intrinsic motivation and self-direction, but limits opportunities for recognizing excelling students. Discretionary grading, which includes letter (F- to A+) and numeric (0% to 100%) representations, supports extrinsic motivation and self-improvement, but promotes unhealthy competition. Both approaches have merit and can effectively measure student achievement in nursing education programs.
E.A. Piterskaya,G.P. Gladilin
Saratov Journal of Medical Scientific Research , 2008,
Abstract: The informative value ofcytologic signs of various epithelial ovaries tumours, which has the diagnostic importance in the process ofcytologic diagnostics, is determined. Groups of basic, the most are established and the least informative signs for differential diagnostics of boundary cystadenoma and cystadenocarcinoma were determined.
Aspecto citológico de tumores intracranianos e do canal vertebral
Campos, Ivelise de Souza;Chimelli, Leila;
Arquivos de Neuro-Psiquiatria , 1993, DOI: 10.1590/S0004-282X1993000200008
Abstract: we present the cytologic aspects of 137 tumors operated by neurosurgeons, including 12 astrocytomas, 4 anaplastic astrocytomas, 26 glioblastomas, 7 oligodendrogliomas, 5 meduloblastomas, 8 schwannomas, 17 meningiomas, 13 pituitary adenomas, 20 metastatic tumors and 18 assorted tumors and nonneoplastic lesions. we have also analysed cytologically samples of normal nervous tissue obtained from autopsies, aiming at its recognition and distinction from the neoplastic tissue in biopsies. the tumors were analysed in smears which were subsequently compared with the histological sections. although it is important to observe cytological details in the tumor, occasionally cells are arranged in such a way, that an overview of the smear pratically allows the diagnosis of the tumor.
Estrategia de intervención en mujeres con citologías alteradas negadas al seguimiento
Gutiérrez Machado,Mario; Suárez González,Juan Antonio; Cabreras Suárez,Damaris;
Revista Cubana de Obstetricia y Ginecolog?-a , 2011,
Abstract: a pre-test and post-test intervention study was conducted to determine the effect of educational intervention in patients with altered cytology who refused follow-up in cervix pathology consultation from the "octavio de la concepción y de la pedraja" teaching polyclinic of camajuaní municipality from january 1 to december 31, 2009 contributing to its insertion in the early care program of cervicouterine cancer and to characterize the sample according to the interesting epidemiological variables for study, to assess the causes influencing in the negative of this patients to carry out the follow-up and to verify the usefulness of the educational intervention in the patient's reinsertion in the program. from a universe of 33 women and the previous informed consent, a sample of 21 patient residents in the urban area was taken. among the main results obtained it was found that those qualified like absents those patients with a secondary school level and the age group more affected was that of 35-39 years. the major causes of absence were the unconcern and the fair. we conclude indicating that educational intervention was effective since the patient's knowledge level rose with a significant reincorporation of patients to the program.
Development and Evaluation of a Groundnut In-Shell Grader  [PDF]
Adepoju B. Fashina, Aminu Saleh, Fatai B. Akande
Agricultural Sciences (AS) , 2015, DOI: 10.4236/as.2015.62021
Abstract: Groundnuts marketed from farms are generally referred to as groundnuts in-shell. When freshly harvested, they may contain some dirt, vines and other foreign materials. Grades of these stocks are established based on intended use. Groundnut producers and commercial buyers use the grade as guidelines for trading. Grading aims at raising the quality and value of the product. Grading is generally limited to measurement of physical properties, such as, size distributions of the pods and percentage by weight of shelled kernels in the undecorticated groundnuts and percentage by weight of foreign materials. A groundnut grader was designed and developed. It was designed to sort three selected groundnut varieties commonly cultivated in Nigeria into three grades based on the geometric dimensions of the selected varieties. These varieties are SAMNUT 10, 14 and 18.Analyses of grading trials indicate that while SAMNUT 10 exhibits the three grades, the other varieties (SAMNUT 14 and 18) can only be graded into two grades. The grader has a rated capacity of grading 224 th-1 of undercorticated pods. The maximum ranges within each grade when all the varieties were considered were: grade I—15.81 mm to 18.05 mm, grade II—12.44 mm to 15.78 mm and grade III—10.60 mm to 13.30 mm.
Preparaciones de base líquida vs. citología convencional: Adecuación de las muestras y coincidencia de diagnóstico en lesiones orales
Hayama,Fábia H; Motta,Ana CF; Silva,Antonio de Padua G; Migliari,Dante A;
Medicina Oral, Patología Oral y Cirugía Bucal (Ed. impresa) , 2005,
Abstract: objective: to compare specimen adequacy and diagnostic agreement between liquid-based preparations and conventional smears in oral lesions, and to test the viability of immunocytochemical assay in liquid-based preparations from oral carcinoma lesions. material and methods: samples were collected from 44 patients. conventional smears were prepared first, using a cytobrush device. then the brush, containing the residual material, was immersed in a preservative fluid. the sample in the preservative fluid was processed according to the manufacturer directions (autocyte, inc. elon college, north carolina, usa). slides of both techniques were stained by papanicolaou method. for immunocytochemical assay, a cytokeratin pool ae1/ae3 (dako, ca, usa) was applied in liquid-based preparations from oral carcinoma lesions following the streptavidin-biotin-peroxidase method. fisher?s exact test was used; significance was set for p ≤0.05. results: both techniques agreed on cytologic diagnosis in every case they yielded an adequate specimen; in 3 cases conventional smear resulted in hypocellularity and therefore inadequate for analysis. on specimen analysis, the liquid-based cytology demonstrated a statistically significant, 41% overall improvement in smear thickness and 66% in cell distribution (p ≤0.05), and a reduction in cell overlapping and presence of blood (p ≤0.05). the cell morphology was better visualized in the liquid-based preparations. the immunocytochemical assay reactions were positive in all malignant cases, the visualization of the immunostained cells being especially clear. conclusion: both, the liquid-based preparation and conventional smear, are diagnostically reliable; the liquid-based method showed an overall improvement on sample preservation, specimen adequacy, visualization of cell morphology and reproducibility.
Valor do esfrega?o no diagnóstico per-operatório dos tumores provenientes de neurocirurgias
Chimelli, Leila;Campos, Ivelise de Souza;
Arquivos de Neuro-Psiquiatria , 1993, DOI: 10.1590/S0004-282X1993000200007
Abstract: the smear technique has been used for rapid diagnosis of tumors removed in neurosurgeries in many neuropathological centers. in order to> assess the diagnostic accuracy of this technique, we examined 137 smears and made a cytohistological correlation. our cases include 12 astrocytomas, 4 anaplastic astrocytomas, 26 glioblastomas, 7 oligodendrogliomas, 5 medulloblastomas, 8 schwannomas, 17 meningiomas, 13 pituitary adenomas, 20 metastatic tumors and 18 assorted tumors and non neoplastic lesions. the correct diagnosis was made in 91.2% of the cases which coincides to the literature. the knowledge of the localization and the characteristic morphologic features of some tumors were important for the diagnosis. the ability to recognize normal nervous tissue in smears was important even to help the surgeon to reach the tumor. we believe that the use of smears should be encouraged in our country in view of the simplicity of its preparation and accuracy of results.
Application of the cytochemical and cytologic methods in diagnosing and preventive treatment of generalized periodontitis in patients suffering from bronchial asthma and receiving glucocorticosteroid therapy
Babenko V.M.
Морфолог?я , 2009,
Abstract: The aim of the investigation was to estimate indices of cytochemical and cytologic methods for diagnosing of generalized periodontitis and dynamic following of preventive treatment results in patients suffering from bronchial asthma and receiving glucocorticosteroid therapy.The results of studying 117 patients with generalized periodontitis (95 patients suffering from generalized periodontitis and bronchial asthma; 22 patients in the group for comparison) showed that the level of cuccinatedehyrogenase and -glycerophosphatdehyrogenase alters according to the clinical course of generalized periodontitis, wich allows to objectively evaluate treatment efficaly and completeness of arresting the inflammatory process in the parodontium. It was proved that cytochemical changes and cytologic picture correlate with severity of generalized periodontitis in patients suffering from bronchial asthma and receiving glucocorticosteroid therapy. Such changes may be used for giagnosing and dynamic follow-ing of the patients.
Características de los bovinos faenados en la Xa Región (Chile) según las pautas indicadas en las normas oficiales de clasificación y tipificación
Archivos de medicina veterinaria , 1999, DOI: 10.4067/S0301-732X1999000100008
Abstract: the present study describes the characteristics of 114.666 cattle slaughtered during 1994 in the 22 slaughterhouses functioning within the xth region and the corresponding carcasses produced according to the terms of the official chilean standards for cattle classification and carcass grading. the following distribution of classes was found, based on age by dental chronometry (only milk teeth present=dl, levelled central milk teeth=dl*, number of permanent incisors present=2-8d, presence of levelled permanent second medials=8d*) and sex: 40.3% of young steers (dl* or 2d); 16.1% of heifers (dl* or 2d), 1.5% of young bulls (dl*); 10.6% of steers (4-6d); 7.6% of young cows (4-6d); 9.0% of adult cows (8d); 6.1% of old cows (8d*), 0.0% of bulls castrated as adults (2-8d*), 2.4% of bulls (2-8d*), 4.2% of oxen (8d or 8d*) and 2.2% of calves (dl). the distribution of the carcasses within the official grading categories (v-a-c-u-n-o) was as follows: v = 55.9%; a = 12.7%; c = 4.6%; u = 15.2%; n = 10.4% and o = 1.2%. the proportion of carcasses falling into grades 0 (none), 1(light), 2 (abundant) and 3 (excess ) of subcutaneous fat cover was 10.1%; 78.3%; 10.2% and 1.4%, respectively. some 7.7% of carcasses presented a degree of bruising; of the latter, 4.8% were classified as degree 1 (affecting only subcutaneous tissues), 2.1% as degree 2 (affecting subcutaneous and muscular tissue) and 0.8% as degree 3 (affecting also bone). it was concluded that within the xth region, predominantly young cattle are slaughtered, especially young steers and heifers, producing carcasses with a light fat cover and graded as v. only a small proportion of carcasses presented bruising serious enough (degree 2 or 3) to degrade the carcasses
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