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Search Results: 1 - 10 of 24626 matches for " cardiovascular disease "
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Effectiveness of a Short Duration Training Programme in the Physical Fitness of Patients with High-Moderate Risk of Cardiovascular Disease  [PDF]
Felícitas García-Ortún, Angeles Jaén, Laura Sucarrats, Lidia González-Gil, Sandra Sabarich, Judit Novo, Alejandro de la Sierra, Amparo Alvarez-Au?ón, Roser Garreta
Open Journal of Preventive Medicine (OJPM) , 2015, DOI: 10.4236/ojpm.2015.55025
Abstract: Introduction: It is not known what the minimum duration of training programme is effective in primary prevention of cardiovascular disease. The objective of this study is to determine the effectiveness in physical fitness and exercise of the training programme of 8 weeks of duration with two modalities (2 or 3 sessions per week) in subjects with moderate-high risk of cardiovascular disease in a primary care setting. Main Findings: A significant increase in the six-minute walk test was observed (from 488 ± 87.4 m to 532 ± 68.0 m, p < 0.0001). A significant increase of exercise duration (from 11.4 ± 3.0 min to 12.3 ± 3.0 min, p < 0.0001) and a delay in the anaerobic threshold (from 8.8 ± 2.9 min to 10.1 ± 2.5 min, p < 0.0001) during the ergometric tests were also observed. The proportion of patients exercising regularly increased significantly (from 36.1% to 83.3%, p < 0.0001). Both modalities of training programme improved fitness and physical activity, without significant differences between them. Conclusion: Our study shows that a structured training programme of two months of duration with 2 or 3 sessions per week significantly improves the fitness and physical activity of patients with moderate-high risk of cardiovascular disease.
The relationship between cardiovascular disease risk factors and gender  [PDF]
Chung-Min Cho, Young-Mi Lee
Health (Health) , 2012, DOI: 10.4236/health.2012.46051
Abstract: The purpose of this study was to investigate the relationship between three socioeconomic sta- tuses and five behavior-related cardiovascular risk factors by gender, based on data from the Third Korea National Health and Nutrition Examination III. Data from 4556 people were analyzed. The propensity toward obesity, hypercholesterolemia, and physical inactivity was significantly higher in women than in men. Hypertension and smoking were significantly more prevalent in men than in women. The differences in the prevalence of cardiovascular disease risk factors by gender is important and should be considered when developing programs to reduce the incidence of cardiovascular diseases.
The Relationship between Thyroid Hormone Levels and Corrected QT Interval and QT Dispersion in Non-Diabetic Hemodialysis Patients  [PDF]
Heo-Yeong Kim, Ji Soo Kim, Seung Eun Suh, Yu Kyung Hyun, Kyeong Mi Park, Hyung-Jong Kim
Open Journal of Nephrology (OJNeph) , 2014, DOI: 10.4236/ojneph.2014.41003

Background: Cardiovascular disease and sudden cardiac death are common in hemodialysis patients. These cardiac complications are often associated with prolonged QTc interval (QTc) and QTc dispersion (QTcd). Subclinical hypothyroidism (SH) can alter autonomic modulation of heart rate and cause increased inhomogeneity of ventricular recovery time. We aimed to evaluate the relationship between thyroid hormone levels and QTc and QTcd in non-diabetic hemodialysis patients. Methods: We enrolled 29 non-diabetic hemodialysis patients without thyroid disease. After each hemodialysis session, a 12-lead ECG was recorded. Before each hemodialysis session, routine laboratory tests and measurement of thyroid hormone levels were performed. Patients were divided into 2 groups according to QTc (group 1 QTc < 430 ms, group 2 QTc ≥ 430 ms). We examined the relationship between QTc or QTcd and thyroid hormone in the respective groups and then compared the results from the 2 groups. Results: The mean age was 54.06 ± 14.72 years and the means of QTc and QTcd were 433.82 ± 22.03 ms, 59.10 ± 28.29 ms, respectively. Homocysteine levels were significant higher in group 2 than group 1 (p < 0.05) and QTcd was comparable between groups. In group 1, QTc and QTcd were not significant correlated with TSH, T3, fT4 and biochemical parameters. In group 2, QTc was significant positively correlated with TSH (p < 0.05) and QTcd was

Nanomedicine: Tiny Particles and Machines, from Diagnosis to Treatment of Cardiovascular Disease, Provides Huge Achievements  [PDF]
Md. Ismail, Md. Faruk Hossain, Md. Fazlul Karim, Hossain Uddin Shekhar
Advances in Bioscience and Biotechnology (ABB) , 2015, DOI: 10.4236/abb.2015.69064
Abstract: Cardiovascular disease is one of many reverberating ailments that affect and kill hundreds of thousands of people around the world. To date treatments that offer improvement in the health condition of diseased people include the most promising nanomedicine although it is in its infancy, yet attaining attention from researchers of top notch day by day. In this current review importance is given on the application of nanomedicine in the diagnosis as well as treatment of cardiovascular disease.
Prediction of Cardiovascular Disease in suburban population of 3 municipalities in Nepal
R Koju,R Gurung,P Pant,S Humagain,CM Yogol,A Koju,K Manandhar,B Karmacharya,TRS Bedi
Nepalese Heart Journal , 2011, DOI: 10.3126/njh.v8i1.8328
Abstract: Background Cardiovascular disease (CVD) is a major cause of morbidity and mortality throughout the world including Nepal. The assessment of risk factors responsible for CVD can predict 10 year risk of CVD. World Health Organization (WHO) risk assessment chart, specially designed for South East Asia Sub-region D can predict the risk of CVD in Nepal. Method and Materials A total 532 study population from Panauti, Banepa and Dhulikhel were calculated their 10 year risk of CVD using WHO/ISH risk prediction chart on the basis of risk factors: age, gender, smoking status, diabetes, systolic blood pressure and total cholesterol. Result Ten year risk of developing cardiovascular disease is less than 10% among the population less than 50 years, irrespective of gender. 5% of male population had more than 10% chance of developing cardiovascular events in next ten years. One third of 60 – 69 years people had more than 10% chance of developing cardiovascular disease whereas it increased to 50% among 70 years and older group. Conclusion The assessment of risk factors is quite easy and cheap tool to predict the cardiovascular event, which support to practice the good clinical management to prevent the cardiovascular morbidity and mortality. ? DOI: http://dx.doi.org/10.3126/njh.v8i1.8328 Nepalese Heart Journal Vol.8(1) 2011 pp.3-7
Risk factors distribution and cardiovascular disease prevalence in the Italian population: The CHECK study  [PDF]
Elena Tragni, Alessandro Filippi, Manuela Casula, Giampiero Favato, Ovidio Brignoli, Claudio Cricelli, Andrea Poli, Alberico L. Catapano
Open Journal of Epidemiology (OJEpi) , 2012, DOI: 10.4236/ojepi.2012.24014
Abstract: Objective: To evaluate the distribution of cardiovascular risk factors and the prevalence of cardiovascular disease in a sample of the Italian population. Methods: CHECK (Cholesterol and Health: Education, Control and Knowledge) is a cross-sectional observational study in a randomised sample of the Italian adult population aged 40 - 79 years, in the setting of general practice. Results: 5846 subjects (50.3% male) were included in the analysis. The mean age [±SD] of the observed cohort was 57.8 (±10.3) years. One out of five subjects smoked cigarettes and almost 80% didn’t engage in regular leisure-time physical activity. The mean blood pressure was 132.0 [±14.7]/81.2 [±7.9] mmHg. The total and LDL-cholesterol levels were respectively 205.3 [±35.9] mg/dL and 124.9 [±29.9] mg/dL. The mean glucose concentration was 98.3 [±28.2] mg/dL. The prevalence rate of hypertension, hypercholesterolemia, and type 2 diabetes were respectively 51.8%, 55.6%, and 13.0%. 8.9% of the observed subjects had a history of cardiovascular events, while in the primary prevention group the 10-year-risk of coronary heart disease (Framingham algorithm) was 10.1% [±8.3%] and of cardiovascular disease (CUORE algorithm) was 5.2% [±5.9%]. Conclusion: The CHECK study provides a detailed description of a randomised sample of the Italian population, contributing to evaluate the prevalence of cardiovascular risk factors and the main cardiovascular disease in Italy and to provide a baseline to set priorities and objectives for future intervention of health policy.
Major study finds no link between gum disease and CV risk
Lyford Joanna,Howell TH,Ridker PM,Ajani UA
Current Controlled Trials in Cardiovascular Medicine , 2001, DOI: 10.1186/cvm-2001-72050
The antithrombotic effects of onion filtrates in rats and mice  [PDF]
Kanae Hyodo, Izumi Horii, Masaru Nishino, John C Giddings, Junichiro Yamamoto
Health (Health) , 2011, DOI: 10.4236/health.2011.36055
Abstract: The prevention of arterial thrombotic disease has a high priority in developed countries. An inappropriate diet is known to enhance the risk for acute thrombotic events, and a regular diet with proven antithrombotic effects might be a beneficial way to prevent disease. The present study was undertaken as part of a series of in-vestigations to examine various vegetables and fruits for antithrombotic activity, and to add to the previously reported data on different onion varieties produced in the northern part of Japan (Hokkaido). For this purpose, a sophisticated method to assess shear-induced platelet reac-tivity/thrombolysis in vitro (The Global Throm-bosis Test, GTT) was used to screen 5 different varieties of onion produced in the middle part of Japan (Awaji Island). The different onion varie-ties demonstrated a variable effect on thrombo-sis, and one particular variety, designated ONA-03, appeared to exert an antithrombotic effect. Another variety, ONA-01, appeared to have prothrombotic activity by inhibiting spon-taneous thrombolytic activity. The especially effective variety was further investigated using an in vivo, laser-induced thrombosis model in mice. The heat stable antithrombotic activity in vitro and in vivo was demonstrated to be due to antiplatelet activity. The present findings added to the list of antithrombotic fruits and vegeta-bles.
Trends in Dietary Intakes and Serum Cholesterol Levels over 50 Years in Tanushimaru in Japanese Men  [PDF]
Hisashi Adachi, Yuji Hirai, Satoshi Sasaki, Mika Enomoto, Ako Fukami, Eita Kumagai, Eishi Esaki, Tsutomu Imaizumi
Food and Nutrition Sciences (FNS) , 2011, DOI: 10.4236/fns.2011.25068
Abstract: We investigated the relationship between time trends in dietary intakes and serum cholesterol levels in a Japanese cohort of the Seven Countries Study, in Tanushimaru, a typical farming town on Kyushu Island. Total subjects were 628 in 1958, 539 in 1977, 602 in 1982, 752 in 1989, 402 in 1999, and 329 in 2009, and all of the subjects were men aged 40 - 64 years. Eating patterns were evaluated by 24-hour dietary recall from 1958 through 1989, and by a food frequency questionnaire in 1999 and 2009. We also measured serum cholesterol levels in each health examination. The total energy intake decreased from 2,837 kcal in 1958 to 2,289 kcal in 2009. The carbohydrate intake in percentage of total energy intake decreased markedly, from 84% in 1958 to 58% in 2009, in contrast to large increases during this period in protein intake (from 11% to 16%) and fat intake (from 5% to 22%). In proportion to the dramatic change in protein and fat intake, serum cholesterol levels showed large increases (from 152.5 mg/dl to 207.7 mg/dl). Despite of such big dietary changes toward a westernized diet, incidence of coronary heart disease has not increased in our cohort for a couple of decades. However, careful surveillance is needed in the future because of the remarkably increasing intake of fats.
The effect of sustained, long-term changes in alcohol intake on cardiovascular risk  [PDF]
Ulla Toft, Charlotta Pisinger, Mette Aadahl, Allan Linneberg, Cathrine Lau, Torben J?rgensen
Open Journal of Preventive Medicine (OJPM) , 2012, DOI: 10.4236/ojpm.2012.24063
Abstract: Objective: To investigate whether sustained long-term changes in alcohol intake are predictive of cardiovascular risk. Methods: The study population was a subpopulation of the five-year intervention study, Inter99 study, (1999-2006), Copenhagen, Denmark (n = 2117; 30 - 60 years). Alcohol intake was assessed by questionnaires at baseline, one-, three- and five-year follow-up. The associations between sustained long-term changes in alcohol intake and cardiovascular risk factors (HDL and non-HDL cholesterol, systolic and diastolic blood pressure (BP); the absolute risk of ischemic heart disease (CRS)) at five-year follow-up were explored by linear regression models. The alcohol variables were tested for linear association with the response variable. Results: Sustained increased alcohol intake was significantly associated with increased CRS (β = 0.0028; P = 0.006) and a decreased HDL cholesterol (β = -0.0028; P = 0.005). Among participants with a moderate overall alcohol in-take at baseline increased alcohol intake was significantly associated with an increased plasma triglyceride (β = 0.0069; P = 0.04). No association with triglyceride was found for participants with a high alcohol intake. Change in wine intake was significantly negatively associated with changes in diastolic BP (β = 0.0015; P = 0.02). Conclusions: Sustained increase in the long-term intake of alcohol was a significant risk factor for an increased CRS, increased triglyceride level and decreased HDL cholesterol. Increased wine intake was associated with decreased diastolic BP.
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