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Search Results: 1 - 10 of 14331 matches for " bone diseases "
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Evaluation of periodontal parameters in postmenopausal women
"Sarlati F.,Talaeipour AR.,Rashedi L. ? Comparison of the accuracy of digital "
Journal of Dental Medicine , 2005,
Abstract: Background and Aim: It has been suggested that osteoporosis may be a predisposing factor for periodontitis and tissue destruction, thus periodontitis and mandibular bone density might be related. The purpose of the present study was to evaluate the clinical signs of periodontal tissue destruction in postmenopausal women. Materials and Methods: In this cross-sectional study, 60 postmenopausal women (51 to 78 years of age) underwent radiographic examination of the right mandibular premolar. Mandibular bone density (MBD) was measured using optical densitometry. Periodontal status variables examined included: probing pocket depth (PPD), clinical attachment level (CAL), bleeding on probing (BOP) and plaque index (PLI). Data were analyzed by statistical tests using P<0.05 as the limit of significance. Results: This study found no statistically significant association between the four indicators of periodontal disease and mandibular bone density, but there was statistically significant association between mandibular bone density and the number of remaining teeth. There was also statistically significant association between PPD and the number of remaining teeth. Conclusion: These findings suggest that individuals with high MBD seem to retain teeth with deep periodontal pockets more easily than those with lower MBD.
Nifedipina promove diminui??o da qualidade óssea em ratas com osteopenia
Bertoncello, Dernival;Silva, Andrezza Ferreira da;Borges, Juliana Almeida de Souza;
Fisioterapia e Pesquisa , 2008, DOI: 10.1590/S1809-29502008000400007
Abstract: the aim of this study was to assess, by biomechanical and physical parameters, the bone quality of femurs from ovariectomized female rats treated with nifedipine. twenty eight wistar female rats, 4 months old, were divided into four groups: intact (int); intact treated with nifedipine (int+nfd); ovariectomized treated with saline (ovx+sal); ovariectomized treated with nifedipine (ovx+nfd). treatment was carried out for eight weeks, six days per week, with administration of 10 mg of nifedipine or 0.1/100g bw of saline, by gavage. after removing the right femur of each animal, maximum load support, mineral density, and bone quality were assessed. results were statistically analysed and significance level set at p<0.05. a significant reduction of maximal load support was found in femur of rats treated with nifedipine (ovx+nfd and int+nfd groups). in the latter group, a significant increase in mineral density was noticed. results show that treatment with nifedipine resulted in lower bone quality.
Desenvolvimento de um modelo experimental de falha óssea infectada na ulna de coelhos
Azi, Matheus Lemos;Kfuri Junior, Mauricio;Martinez, Roberto;Salata, Luis Antonio;Paccola, Cleber Antonio Jansen;
Acta Ortopédica Brasileira , 2012, DOI: 10.1590/S1413-78522012000300002
Abstract: objective: develop a model that allowed the study of bone regeneration in infection conditions. method: a 15 mm defect was surgically created in the rabbit ulna and inoculated with 5x108 colony-forming units (cfu) of s. aureus. surgical debridement was performed two weeks after and systemic gentamicin was administered for four weeks. animals were followed up to 12 weeks to evaluate infection control and bone regeneration. result: bone regeneration was inferior to 25% of the defect in radiological and histological analysis. conclusion: infected bone defect of 15 mm in the rabbit ulna was unable to achieve full regeneration without further treatment. level of evidence v, experimental study.
Reabsor??o no metabolismo ósseo de pacientes HIV-positivos
Silva-Santos, Antonio Carlos;Matos, Marcos Almeida;Galv?o-Castro, Bernardo;
Acta Ortopédica Brasileira , 2009, DOI: 10.1590/S1413-78522009000200010
Abstract: introduction: hiv-infected patients show osteoporosis or densitometric osteopenia at a rate of 28-50%. the objective of this study is to check the changes on reabsorption/ development rates on these patients. materials and methods: a systematic review was carried out with meta-analysis of controlled studies assessing the correlation between osteopenia and/ or bone metabolism changes with hiv infection. all studies including osteocalcin or ntx with corresponding markers of bone development and reabsorption were included. five studies were classified as class-iii evidence, and involved 456 hiv-positive individuals and 590 controls. ntx had a significant increase (p < 0.00014) on the hiv-positive group, while osteocalcin has shown to be unchanged. conclusion: this study allows us to conclude that, during hiv infection, the ntx marker is significantly high, reflecting a high reabsorptive activity on the bone tissue. this suggests an important role on osteoclastic activity in bone loss for hiv-positive patients.
Influence of different durations of estrogen deficiency on alveolar bone loss in rats
Amadei, Susana Ungaro;Souza, Daniela Martins de;Brand?o, Adriana Aigotti Haberbeck;Rocha, Rosilene Fernandes da;
Brazilian Oral Research , 2011, DOI: 10.1590/S1806-83242011000600011
Abstract: the purpose of this study was to morphometrically evaluate the influence of different durations of ovariectomy-induced estrogen deficiency on alveolar bone loss associated with ligature-induced bone loss in rats. sixty female wistar rats were randomly assigned to ovariectomy (ovx test group) or sham operation (sham control group). the ovx and sham groups were each distributed into three subgroups of ten rats each according to the duration of estrogen deficiency (30, 60 and 90 postoperative days). in all groups, for the last 30 days of the experimental period, cotton ligatures were placed around the cervix of the right upper second molar; the contralateral tooth was left unligated to serve as a control. the maxillary bones were removed, and the alveolar bone loss was analyzed by measuring the distance between the cementoenamel junction and the alveolar bone crest at the buccal site of the right upper second molar. a comparison between the ligated and unligated groups verified the presence of ligature-induced alveolar bone loss (p < 0.05). no significant differences were observed among the unligated groups (p > 0.05). a significant increase in bone loss was observed when ligation occurred 90 days after ovariectomy compared with the sham group (p < 0.05). these results demonstrate that long-term estrogen deficiency affects ligature-induced alveolar bone loss.
Pectus carinatum
Coelho, Marlos de Souza;Guimar?es, Paulo de Souza Fonseca;
Jornal Brasileiro de Pneumologia , 2007, DOI: 10.1590/S1806-37132007000400017
Abstract: among the deformities of the thoracic wall,pectus carinatum has not received the same attention as has pectus excavatum. few pulmonologists, pediatricians, and thoracic surgeons are aware of the approaches to treating this condition. as a consequence, patients with pectus carinatum are not referred for treatment. this deformity, with an incidence of 1:1000 teenagers, is oligosymptomatic. however, for aesthetic and emotional reasons, it accounts for a large number of medical appointments. such patients are introverted and do not engage in physical activities, since they are unwilling to expose their chest, which also discourages them from going to the beach or to swimming pools. the diagnosis is clinical and visual, and details are obtained through chest x-rays and computed tomography. the treatment is based on a well-known organogram that summarizes orthopedic and surgical procedures. dynamic compression, combined with physical exercises, is indicated for teenagers with flexible thorax in inferior and lateral pectus carinatum, with limited indication for those with superior pectus carinatum. for individuals of any age with rigid thorax, surgery is indicated for aesthetic reasons. among the techniques described, the modified sternum chondroplasty stands out due to the excellent aesthetic results achieved.
Densitometría ósea y tama?o uterino: una relación de utilidad práctica en mujeres climatéricas
Porcile J,Arnaldo; Gallardo L,Enrique; Duarte R,Patricia;
Revista médica de Chile , 2000, DOI: 10.4067/S0034-98872000001000008
Abstract: background: double beam bone densitometry allows to select climacteric women who will benefit from hormone replacement. however, it is not always affordable in clinical practice. aim: to study possible alternative markers of bone mineral density. patients and methods: a retrospective survey of climacteric women in whom bone mineral density was measured when hormone replacement therapy was started. eighty one women were studied and in 27, uterine size index was obtained from pelvic ultrasound examinations. women with and without uterine size index measurements were analyzed separately. relationships of bone mineral density with age, lapse from menopause, body mass index and uterine size index were sought. results: there was a significant regression between the lapse in years from menopause and lumbar bone mineral density in the group without uterine size index measurements (r2=0.228, anova p=0.014). there was also a significant regression of lumbar bone mineral density with the uterine size index (r2=0.236, anova p=0.01) in those women in whom this measurement was available. no other variables were associated with bone mineral density. conclusion: in this group of patients, the lapse after menopause and uterine size index are predictors of lumbar bone mineral density (rev méd chile 2000; 128: 1127-31).
Densitometría ósea y tama o uterino: una relación de utilidad práctica en mujeres climatéricas Bone mineral density and uterine size: A practical relationship for climacteric women
Arnaldo Porcile J,Enrique Gallardo L,Patricia Duarte R
Revista médica de Chile , 2000,
Abstract: Background: Double beam bone densitometry allows to select climacteric women who will benefit from hormone replacement. However, it is not always affordable in clinical practice. Aim: To study possible alternative markers of bone mineral density. Patients and methods: A retrospective survey of climacteric women in whom bone mineral density was measured when hormone replacement therapy was started. Eighty one women were studied and in 27, uterine size index was obtained from pelvic ultrasound examinations. Women with and without uterine size index measurements were analyzed separately. Relationships of bone mineral density with age, lapse from menopause, body mass index and uterine size index were sought. Results: There was a significant regression between the lapse in years from menopause and lumbar bone mineral density in the group without uterine size index measurements (r2=0.228, ANOVA p=0.014). There was also a significant regression of lumbar bone mineral density with the uterine size index (r2=0.236, ANOVA p=0.01) in those women in whom this measurement was available. No other variables were associated with bone mineral density. Conclusion: In this group of patients, the lapse after menopause and uterine size index are predictors of lumbar bone mineral density (Rev Méd Chile 2000; 128: 1127-31).
Tumores ósseos benignos e les?es ósseas Pseudotumorais: tratamento atual e novas tendências
Drumond, José Marcos Nogueira;
Revista Brasileira de Ortopedia , 2009, DOI: 10.1590/S0102-36162009000500003
Abstract: the treatment of benign bone tumors (bbt) and tumor-like bone lesions (tbl) has observed the introduction of new drugs, such as intravenous bisphosphonates, which have ossified bone lesions caused by fibrous dysplasia. aneurismal bone cyst has been treated with sclerosing agents by percutaneous injection, yielding good results. adjuvants allow joint salvage, maintenance of movements and function, with low rates of recurrence. among them, the most used ones are bone cement (pmma), phenol, nitrogen-based cryotherapy, hydrogen peroxide, ethanol and radiotherapy. new methods of treatment include thermal ablation with radiofrequency and laser, mainly utilized for treating osteoid osteoma. arthroscopy allows resection of benign intra-joint lesions and assists the surgery of subchondral tumors. a great advance is the utilization of synthetic bone substitutes, which are a mixture of osteoinductive growth factors and osteoconductive ceramics, and have presented comparable results to autogenous bone grafts. there is a recent trend for closed treatments, with percutaneous injection of demineralized bone matrix (dbm) and calcium sulfate. autogenous cancellous bone graft remains as the gold standard. vascularized fibula graft, on the other hand, incorporates faster in the treatment of large destructive lesions. also, allogenic cortical support allows structural augmentation for aggressive tumors. freeze-dried allografts are used to fill contained defects and as expanders of autografts. joint endoprosthesis may be used in large destructive lesions of the distal femur, hip and shoulder.
Eficácia do sistema de estadiamento de enneking no tratamento dos tumores ósseos benignos e les?es ósseas pseudotumorais
Drumond, José Marcos Nogueira;
Revista Brasileira de Ortopedia , 2010, DOI: 10.1590/S0102-36162010000100009
Abstract: objective: to evaluate the efficacy of the enneking staging system in determining the prognosis, planning surgical treatment and indicating adjuvant therapy for the treatment of benign bone tumors (bbt) and tumor-like bone lesions (tbl). methods: a retrospective multicentric, descriptive, nonrandomized study was carried out comprising a large series of 165 patients with a total of 168 benign bone tumors and pseudotumoral bone lesions. the patient sampling was typical, and matched the literature in all aspects. all the patients were classified according to the enneking staging system, and were reevaluated after either conservative or surgical treatment, to establish the efficacy of the system. treatment options and clinical complications were analyzed. results: the results of the treatment provided 95.2% agreement with the enneking staging system, with a 95% confidence interval of between 90.8 and 97.9%. of the 168 tumors treated, only eight (4.8%) could not be controlled by the initial treatment indicated by the enneking staging system. tumors classified as active were the most prevalent, comprising 73.2% of the lesions. tumor recurrence was significantly higher (p<0.001) for the aggressive stage. the study also suggested that wide surgical margins could be more efficient in reducing the recurrence of aggressive lesions (p>0.001). all the patients staged as latent were healed. bone cement (pmma) was an effective adjuvant when associated with marginal surgery. for latent and active lesions, the study demonstrated the efficacy of treatments with observation only, or with excision, with or without autogenous bone graft. conclusion: the results confirm that the enneking staging system was very efficient in determining prognosis, assisting surgical planning and indicating adjuvant therapy in the treatment of bbt and tbl.
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