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Search Results: 1 - 10 of 5960 matches for " bone adhesive "
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Research on Calcium Phosphate Cement Bone Adhesive
YANG Sheng-Bing, WANG Jing, LIU Chang-Sheng
无机材料学报 , 2013, DOI: 10.3724/sp.j.1077.2013.12318
Abstract: Using citric acid and chitosan as hardening liquid, and calcium phosphate cement (CPC) as powder, gum-like adhesive bone cement is obtained after mixing the powder and liquid components together, which can be used as calcium phosphate cement bone adhesive (CPCBA). The effect of citric acid concentration on compressive strength, setting time and hydration products were investigated. In vitro cytocompatibility of the cements was also researched through cell culture on the cement surface. The results show that setting time is shorten and anti-washout is improved by introducing citric acid. Cohesion strength increases owing to chitosan chelated with calcium ion of CPC. The cements are transformed to hydroxyapatite after incubation 3 d in SBF and osteoblasts (MC3T3-E1) can attach and proliferate on the surface. Results indicate that the calcium phosphate cement bone adhesive is a suitable adhesive material for comminuted fracture.
A method to screen and evaluate tissue adhesives for joint repair applications
Dehne Tilo,Zehbe Rolf,Krüger Jan,Petrova Aneliya
BMC Musculoskeletal Disorders , 2012, DOI: 10.1186/1471-2474-13-175
Abstract: Background Tissue adhesives are useful means for various medical procedures. Since varying requirements cause that a single adhesive cannot meet all needs, bond strength testing remains one of the key applications used to screen for new products and study the influence of experimental variables. This study was conducted to develop an easy to use method to screen and evaluate tissue adhesives for tissue engineering applications. Method Tissue grips were designed to facilitate the reproducible production of substrate tissue and adhesive strength measurements in universal testing machines. Porcine femoral condyles were used to generate osteochondral test tissue cylinders (substrates) of different shapes. Viability of substrates was tested using PI/FDA staining. Self-bonding properties were determined to examine reusability of substrates (n = 3). Serial measurements (n = 5) in different operation modes (OM) were performed to analyze the bonding strength of tissue adhesives in bone (OM-1) and cartilage tissue either in isolation (OM-2) or under specific requirements in joint repair such as filling cartilage defects with clinical applied fibrin/PLGA-cell-transplants (OM-3) or tissues (OM-4). The efficiency of the method was determined on the basis of adhesive properties of fibrin glue for different assembly times (30 s, 60 s). Seven randomly generated collagen formulations were analyzed to examine the potential of method to identify new tissue adhesives. Results Viability analysis of test tissue cylinders revealed vital cells (>80%) in cartilage components even 48 h post preparation. Reuse (n = 10) of test substrate did not significantly change adhesive characteristics. Adhesive strength of fibrin varied in different test settings (OM-1: 7.1 kPa, OM-2: 2.6 kPa, OM-3: 32.7 kPa, OM-4: 30.1 kPa) and was increasing with assembly time on average (2.4-fold). The screening of the different collagen formulations revealed a substance with significant higher adhesive strength on cartilage (14.8 kPa) and bone tissue (11.8 kPa) compared to fibrin and also considerable adhesive properties when filling defects with cartilage tissue (23.2 kPa). Conclusion The method confirmed adhesive properties of fibrin and demonstrated the dependence of adhesive properties and applied settings. Furthermore the method was suitable to screen for potential adhesives and to identify a promising candidate for cartilage and bone applications. The method can offer simple, replicable and efficient evaluation of adhesive properties in ex vivo specimens and may be a useful supplement to e
Evaluation of an Orthodontic Adhesive with Combined Primer and Composite  [PDF]
Yoav Shapinko, Iro Eleftheriadi, Tamar Brosh, Lihi Adler-Abramovich, Moshe Davidovitch, Tatiana Sella-Tunis, Rachel Sarig, Nir Shpack
Open Journal of Stomatology (OJST) , 2018, DOI: 10.4236/ojst.2018.86020
Abstract: Objectives: To investigate the efficacy of a new orthodontic bonding system that incorporates the primer solution in the adhesive. Materials and Methods: 90 anterior bovine teeth were divided in three groups: in Group I, brackets were bonded with Transbond XT system, in Group II with GC Ortho Connect which incorporates the primer in the adhesive, and in Group III, a single layer of primer was applied on the teeth before bonding the brackets with GC Ortho Connect. After a 24-hour latency period, Shear Bond Strength (SBS) and Adhesive Remnant Index (ARI) were measured. In cases with remnants left mainly on the bracket base, energy dispersive X-ray (EDX) spectrometry was performed in order to determine the presence of calcium particles. Selected cases were examined with Scanning Electron Microscopy (SEM) analysis and in nanometer scale with a confocal visible light microscope (μsurf revolver, NanoFocus AG, Germany). Results: The mean SBS values were 7.25 ± 0.58 MPa for Group I, 6.57 ± 0.50 MPa for Group II and 7.33 ± 0.56 MPa for Group III. These differences were not statistically significant (p = 0.562). ARI evaluation showed that the debonding failure happened more frequently within the adhesive interface in Group II, whereas this occurred more often at the tooth-adhesive interface in Group III. However, statistical analysis of the ARI scores showed no significant difference in adhesive remnants among the three groups (p = 0.078). Conclusion: The GC Ortho Connect bonding system can be efficiently used for orthodontic bonding. Adding a layer of primer appears to slightly increase the SBS while causing less adhesive to remain on enamel from which brackets were debonded.
CT Appearance Following Partial Nephrectomy for Renal Cell Carcinoma Using Tissue Adhesive Bioglue  [PDF]
Simona Croituro, Yair Braz, Boaz Moskovitz, Ofer Nativ, Sarel Halachmi
Open Journal of Urology (OJU) , 2013, DOI: 10.4236/oju.2013.32015

Background: The use of biological sealants has greatly increased during nephron sparing surgery. In many cases the bulk of the material was erroneously mistaken for tumor recurrence. Objective: To describe the characteristic appearance of biological adhesive material used for tumor bed closure on computerized tomography (CT) following nephrone sparing surgery (NSS) for renal cell carcinoma, in order to differentiate between typical features of the adhesive material and local tumor recurrence. Design, Setting and Participants: We retrospectively reviewed follow-up CT scans of 120 patients who underwent NSS for T1N0M0 RCC. In all cases tumor bed was closed during surgery with biological tissue adhesive (BioGlue). Results and Limitations: During 1994-2009, 120 patients with a single T1 renal cell carcinoma lesion, underwent NSS with closure of tumor bed with bio adhesive material. There were 66 males and 47 females with mean age of 58.7 years (median: 58 years, range: 28 - 85 years). Mean follow-up time was 45 ± 34 months (median 42, range 12 - 168). During follow-up, 3 patients had local recurrence at the site of previous enucleated lesion. In the first post-operative CT scan the BG appeared as a heterogeneous mass with sharp edges measuring 20 - 70 HU with no attenuation following the injection of contrast material. In subsequent follow-up scans the BG in most patients remained stable in size; in few patients slight reduction in size was observed probably due to the resolution of post-operative hematoma. Tumor

Polyurethane structural adhesives applied in automotive composite joints
Quini, Josue Garcia;Marinucci, Gerson;
Materials Research , 2012, DOI: 10.1590/S1516-14392012005000042
Abstract: in recent years structural adhesives technology has demonstrated great potential for application due to its capacity to transform complex structures into solid unitary and monolithic assemblies using different materials. thus, seams or joints integrate these structures providing, besides a reduction in weight, a considerable increase in the mechanical resistance and stiffness. the increase in the industrial use of structural adhesives is mainly due to their ability to efficiently bond different materials in an irreversible manner, even replacing systems involving mechanical joints. in the automobile industry structural adhesives have been widely used for the bonding of metal substrates, thermoplastics and composites, frequently employing these in combination, particularly glass fiber and polyester resin composites molded using rtm and smc processes. however, the use of urethane structural adhesives in applications involving composites and thermoplastics has been the subject of few investigations. in this study the effects of temperature and time on the shear strength of rtm, smc and abs joints, applying temperatures of -40, 25, 80, 120 and 177 °c and times of 20 minutes and 500 hours, were determined. the objective was to evaluate the performance under extreme conditions of use in order to assess whether these joints could be used in passenger or off-road vehicles. the results showed that the urethane structural adhesive promoted the efficient bonding of these materials, considering that due to the high adhesive strength the failures occurred in the substrates without adversely affecting the bonded area. for each test condition the joint failure modes were also determined.
Using Microgripper in Development of Automatic Adhesive Glue Transferring and Binding Microassembly System  [PDF]
Engineering (ENG) , 2010, DOI: 10.4236/eng.2010.21001
Abstract: A system using microgripper for gluing and adhesive bonding in automatic microassembly was designed, implemented, and tested. The development of system is guided by axiomatic design principle. With a compliant PU microgripper, regional-edge-statistics (RES) algorithm, and PD controller, a visual-servoing system was implemented for gripping micro object, gluing adhesive, and operating adhesive bonding. The RES algorithm estimated and tracked a gripper’s centroid to implement a visual-servoing control in the microassembly operation. The main specifications of the system are: gripping range of 60~80μm, working space of 7mm×5.74mm×15mm, system bandwidth of 15Hz. In the performance test, a copper rod with diameter 60μm was automatically gripped and transported for transferring glue and bonding. The 60μm copper rod was dipped into a glue container and moved, pressed and bonding to a copper rod of 380μm. The amount of binding glue was estimated about 5.7nl.
Dermabond Protape (Prineo) for Wound Closure in Plastic Surgery  [PDF]
Martijn P. J. Loonen, Marc A. M. Depoorter
Modern Plastic Surgery (MPS) , 2012, DOI: 10.4236/mps.2012.22005
Abstract: Dermabond Protape (2-octyl-cyanoacrylate and pressure sensitive adhesive mesh; Prineo, Closure Medical Corporation) is a topical mesh and skin adhesive that forms a strong polymeric bond across opposed wound edges allowing the normal healing process to occur. No published studies have already compared the use of a topical mesh en skin adhesive in wound closure. This study evaluated the possible applications of a combined mesh-adhesive system in 100 plastic surgery operations (14 different surgical procedures) with a mean follow-up of 85.5 days. The rate of allergic reaction, infection, wound dehiscence and hypertrophic scar formation were recorded in relation to patient co-morbidities, medication and tobacco consumption. No technical restrictions were found during the Dermabond Protape application. The average time for the topical mesh and skin adhesive application was 2 minutes. The Dermabond protape was removed 7 through 10 days after the operation. Three patients (3/100 or 3%) reported an allergic reaction without increased scar formation. Hyper-inflammation in one or more wound areas with a micro-abscess were noted in 11 different patients probably due to polyglactin 910 (vicryl) sutures at their scheduled follow-up visit 1 week after their operation. Increased tissue inflammation and scar formation were found in these patients with hypertrophic scars in 1 patient (1/11 or 9.1%). One upper leg wound dehiscence was seen in a diabetes mellitus patient using corticosteroids. Two patients (2/100 or 2%) with a history of tobacco abuse showed a partial wound dehiscence after an abdominoplasty and a partial areola dehiscence after mamma reduction respectively (Table 2).
Osteoclastoma of Proximal Ulna―Atypical Location in a 13-Year-Old Child  [PDF]
Siddaram Patil, Ranjit Kumar Yalamanchili
Open Journal of Orthopedics (OJO) , 2014, DOI: 10.4236/ojo.2014.43009
Abstract: Giant cell tumour (GCT) or osteoclastoma is a very rare locally invasive bone tumour that occurs close to the joint. The ulnar metaphysis is an unusual site for an Osteoclastoma with occurrence rate of 0.45% to 3.2% as reported in literature [1]. Most of the patients seek traditional methods of treatment before orthopaedic consultation and present lately with extensive involvement of the tumour into soft tissues and articular surface, making the joint preservation difficult or impossible. For reconstruction, several options have been described, which include fibular autografts, allografts and cement augmentation. Inherent to all these procedures is the risk of delayed union of the graft and preserving functional mobility of the joint. We report a rare case of a proximal ulna GCT diagnosed in a 13-year-old girl. It was treated with intralesional curettage, and autologous maternal iliac crest bone grafting augmented with bone cement reconstruction.
Refining bioreactor design using autoclavable glass bonding  [PDF]
Cornelia B?hr, Elisabeth Stammen, Sarah Zahlten, Stefan B?hm, Klaus Dilger, Jochen Büchs
Advances in Bioscience and Biotechnology (ABB) , 2011, DOI: 10.4236/abb.2011.24034
Abstract: Selecting the right design of bioreactors is crucial for guaranteeing the reproducibility of bioprocesses. Up to now, conventionally designed bioreactors consist typically of melted or clamped joints. Since melting of borosilicate glass leads to large deformed areas along the joint, the desired geometric reproducibility is not ensured. Moreover, clamping complicates and greatly restricts the bioreactor design. Bonding, however, is advantageous in that it does not alter the material joined and it is easy to use. Furthermore, it has been recently shown that specially developed glass bonding techniques withstand multiple autoclaving cycles. The current research investigated practice-relevant parameters influencing the lifespan of epoxy-or (urethane) acrylate-bonded glass bioreactors. Hereby, the influence of cleaning and sensitivity to fermentation compounds (ethanol and acetic acid) was quantified using glass-glass and glass-stainless steel specimens. Whereas cleaning did not adversely affect the durability of glass bonds, high concentrations of the fermentation compounds ethanol and acetic acid resulted in accelerated corrosion and subsequent bond failure. Moreover, no effect of eight different epoxy and (urethane) acrylate adhesives was observed on selected model organisms Escherichia coli K12 and Hansenula polymorpha wild type. Another objective of this study was to refine the design of two small-scale bioreactors (ca. 250 mL) by replacing clamps and melted joints by adhesive joints. It was found that the bonded bioreactors yielded a higher geometric reproducibility than that of conventional melted or clamped ones. In conclusion, bonded glass joints greatly enhance the geometric reproducibility of bioreactors and, in turn, the reproducibility of bioprocesses. As glass bonding is easy to handle, it opens up new opportunities to design bioreactors that had been previously too expensive and complicated.
Recent Advances in Nanostructured Biomimetic Dry Adhesives
Jeffrey Krahn,Carlo Menon
Frontiers in Bioengineering and Biotechnology , 2013, DOI: 10.3389/fbioe.2013.00022
Abstract: The relatively large size of the gecko and its ability to climb a multitude of structures with ease has often been cited as the inspiration upon which the field of dry adhesives is based. Since 2010, there have been many advances in the field of dry adhesives with much of the new research focusing on developing nanoscale and hierarchical features in a concentrated effort to develop synthetic gecko-like dry adhesives which are strong, durable, and self-cleaning. A brief overview of the geckos and the hairs which it uses to adhere to many different surfaces is provided before delving into the current methods and materials used to fabricate synthetic gecko hairs. A summary of the recently published literature on bio-inspired, nanostructured dry adhesives is presented with an emphasis being placed on fabrication techniques.
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