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Search Results: 1 - 10 of 17142 matches for " biological research "
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Telómeros y Telomerasa: Breve recuento de una historia iniciada por Hermann Müller y Bárbara McClintock
Colombia Médica , 2006,
Abstract: what is the nature of the biological clock that determines the cells aging? what is the way to explain the genesis of diseases associated in aging? the above are only some of the questions whose answer could be found within the modus operandi frame of the telomere-telomerase pair, which had become in objective of study for a number of science men and women since the pioneers hermann müller and barbara mcclintock, until the most recent jack szostak, elizabeth blackburn and carol greider, among others.
Telomere and Telomerase: brief review of a history initiated by Hermann Müller and Barbara McClintock
Lilian Chuaire
Colombia Médica , 2006,
Abstract: What is the nature of the biological clock that determines the cells aging? What is the way to explain the genesis of diseases associated in aging? The above are only some of the questions whose answer could be found within the modus operandi frame of the telomere-telomerase pair, which had become in objective of study for a number of science men and women since the pioneers Hermann Müller and Barbara McClintock, until the most recent Jack Szostak, Elizabeth Blackburn and Carol Greider, among others.
Beliefs and attitudes towards participating in genetic research – a population based cross-sectional study
Samantha M Kerath, Gila Klein, Marlena Kern, Iuliana Shapira, Jennifer Witthuhn, Nicole Norohna, Myriam Kline, Farisha Baksh, Peter Gregersen, Emanuela Taioli
BMC Public Health , 2013, DOI: 10.1186/1471-2458-13-114
Abstract: Participants were recruited at six hospital centers in the NSLIJ system during the summers of 2009 and again in 2011 (n?=?1,041). Those who opted to participate were given a questionnaire containing 22 questions assessing demographics, lifestyle and attitudes towards genetic research. These questions addressed individual participant’s beliefs about the importance of genetic research, willingness to participate in genetic research themselves, and their views on informed consent issues.Respondents took a generally positive view of genetic research in general, as well as their own participation in such research. Those with reservations were most likely to cite concerns over the privacy of their medical and genetic information. Those who were married tended to view genetic research as important, while those in the younger age group viewed it as less important. Prior blood donation of respondents was found to be a predictor of their approval for genetic research. Demographic factors were not found to be predictive of personal willingness to participate in genetic research, or of approval for the opt-out approach to consent.While respondents were generally inclined to approve of genetic research, and those who disapproved did not do so based on an underlying moral objection to such research, there is a disconnect between the belief in the importance of genetic research and the willingness of individuals to participate themselves. This indicates a continued concern for the ways in which genetic materials are safeguarded once they are collected. Also indicated was a general lack of understanding about the various consent processes that go along with genetic research, which should be addressed further to ensure the successful continuation of biobanks.Biobanks are the repository of a large number of individuals’ biological samples, annotated with clinical and/or genetic information. The utilization of data and samples stored in existing biobanks has become the cornerstone of
Decommissioning of the ASTRA research reactor: Dismantling of the biological shield
Meyer Franz,Steger Ferdinand
Nuclear Technology and Radiation Protection , 2006, DOI: 10.2298/ntrp0602079m
Abstract: The paper describes the dismantling of the inactive and activated areas of the biological shield of the ASTRA research reactor at the Austrian Research Center in Seibersdorf. The calculation of the parameters determining the activated areas at the shield (reference nuclide, nuclide vector in the barite concrete and horizontal and vertical reduction behaviors of activity concentration) and the activation profiles within the biological shield for unrestricted release, release restricted to permanent deposit and radioactive waste are presented. Considerations of located activation anomalies in the shield, e.g. in the vicinities of the beam-tubes, were made according to the reactor's operational history. Finally, an overview of the materials removed from the biological shield is given.
Isolation and biological characterization of chicken amnion epithelial cells
Y. Gao,Y. Pu,D. Wang,L. Hou
European Journal of Histochemistry , 2012, DOI: 10.4081/ejh.2012.e33
Abstract: Amniotic epithelial cells (AECs) express Oct4, Nanog and Sox-2, which are necessary for maintaining the undifferentiated state of pluripotent stem cells. AECs additionally express CK19, which is a specific marker of epithelial cells, both in vivo and in vitro. In this research, we investigated the biological characteristics and potential for cell therapy of AECs from 6-day-old chicken embryos. We induced the AECs to differentiate into pancreatic islet-like cells (endoderm), adipocytes and osteoblasts (mesoderm) and neural-like cells (ectoderm), and used immunofluorescence and RT-PCR to detect the expression of AECs specific markers. To assess the differentiation capacity of AECs, passage 3 cells were induced to differentiate into adipocytes, osteoblasts, pancreatic islet-like cells and neural-like cells. The AEC markers, Oct4, Nanog, Sox-2 and CK19, were all positively expressed. Cloning efficiency decreased with increasing passage number. Passage 3 AECs were successfully induced to differentiate into pancreatic islet-like cells, osteoblasts, adipocytes, and neural-like cells. These results suggested that AECs isolated from chicken embryos exhibited the characteristics of the multipotent stem cells. AECs may therefore be ideal candidates for cellular transplantation therapy and tissue engineering.
Research Progress of the Biological Aerated Filter in Wastewater Treatment

窦娜莎, 王琳
Advances in Environmental Protection (AEP) , 2013, DOI: 10.12677/AEP.2013.32011
Biological aerated filters (BAF) is a new wastewater treatment process developed at the end of the 1980s, and after 20 years of research and development, BAF system has been attached extensive importance to Europe, the US, Japan and other developed countries. At present, there are hundreds of engineering examples in the world. Through re-searching domestic and international literatures on BAF, this work endeavored to give an overview of the hot research topics and advances of BAF. Furthermore, the problems and difficulties presented were indicated. Finally, the key points needed to be deliberatively studied were discovered.
Acta Biológica Colombiana , 2009,
Abstract: access to genetic resources (agr) with scientific or commercial purposes is regulated in colombia by decision 391/96 of the andean community of nations and its prescribed norms. during the first years of the implementation of these norms, their effectiveness was almost null as a result of institutional deficiencies and the lack of information and interest of researchers and research institutions. with the purpose to extract lessons from the processes of access applications and to promote an appropriate answer from the environmental authorities, two case studies are examined. the data was taken from public files n.o 2571 and rge0018, at the ministry of environment, house and land development (mavdt). the application of the biotechnology institute of the national university of colombia, has last for 7 years for the authorization of an arg without success; unexpectedly the mavdt has initiated a sanction process on grounds of illegal access. the application presented by the 'temporary union colombian center for bioinformatic and genomics on extreme environments -gebix' the arg was granted and signed after 406 days of proceeding. in the end, the application and negotiation of a contract for arg, requires researcher’s knowledge regarding the arg procedure and appropriate implementation of the access legislation by the mavdt. although the application process is less troublesome for the researcher at the moment, institutional and regulatory adjustments are still required in order to establish an arg procedure that facilitates, instead of preventing, the scientific research.
Bioethics and animal research: A personal perspective and a note on the contribution of Fritz Jahr
Biological Research , 2008, DOI: 10.4067/S0716-97602008000100013
Abstract: reviewing fundamental aspects of bioethics and outlining the work of the bioethics program of the pan american health organization, this paper draws attention to the work of a forgotten pioneer- fritz jahr- who coined the term bioethics in 1927 and anticipated many of the arguments and discussions now current in biological research involving animals
A Scientometric view of some Biological disciplines in Chile
Biological Research , 2002, DOI: 10.4067/S0716-97602002000100012
Abstract: during the last decade the articles published by chilean research centers grew 1,73 which compares to the 2.34 fold increase of mainstream research articles registered as a whole in latin america. however, the relative impact of the chilean publications surpassed that of latin america. in biological sciences, traditionally the strongest research area within chile, latin america also shows a steeper slope of growth. qualitatively, biological disciplines in chile are comparable to those published in latin america although in chile there are specialties as physiology that surpass the average world's impact. the scientometric data is consistent with the fall in individual grants that the chilean research fund (fondecyt) has been allocating during the last decade.
A ciência do desenvolvimento humano: ajustando o foco de análise
Dessen, Maria Auxiliadora;Guedea, Miriam Teresa Domingues;
Paidéia (Ribeir?o Preto) , 2005, DOI: 10.1590/S0103-863X2005000100004
Abstract: the interdisciplinary field of developmental science showed a significant progress in the last decades. this progress has changed the view on the ways of thinking about the study of human development, having a strong impact in the research designs. this article aims to discuss basic concepts and principles that recently guide the definition of the human development concept such as structure, temporality, changes and continuities. it is also emphasized the necessity of adopting a systemic approach to study the developmental process. it means that it is important to analyze the complex and integrated systems considering the genetic, neural, behavioral, and environmental (physical, social, and cultural) levels interacting across time and forming probabilistic trajectories of development.
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