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Spinal anesthesia involves the
introduction of local anesthetics into the subarachnoid space leading to the
loss of sensation
of pain. Common complications following spinal anesthesia include hypotension
leading to nausea and vomiting, failure of the spinal and post dural puncture.
Other uncommon complications include high and total spinal and spinal
haematoma. In this report the patient experienced uncontrollable jerking of the
lower limbs, hypertension, arrhythmias and cardiac arrest refractory to
Amiodarone is used worldwide to treat cardiac
arrhythmias, as well as highly symptomatic cases of atrial fibrillation. With
this expanded use, especially following its 1985 United States Food and Drug
Administration approval, and its use as a long-term therapy in common practice,
reports of cancers temporarily related to amiodarone have begun to increase.
Animal studies, several clinical trials, numerous case reports, and a
population-based cohort study have suggested that cancers may be
associated with amiodarone use. This review focuses on the ever increasing
evidence in the literature that suggests amiodarone therapy, especially with
long-term use, may increase the potential risk of cancer development. It also
expresses the need for more definitive studies to be conducted to provide
clinicians with a clear answer to this important question.