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Search Results: 1 - 10 of 33170 matches for " Zhiwei Huang "
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Exploration the Method of Low Dose Coronary Artery Imaging with Dual-Source CT  [PDF]
Zhiwei Huang, Bo Xiao, Lisha Zhong
Journal of Biosciences and Medicines (JBM) , 2013, DOI: 10.4236/jbm.2013.11002
Abstract: Objective: On the premise that the image quality meets the requirements of clinical diagnosis, we explored the methods to reduce the radiation dose of coronary artery imaging with Dual-Source CT (DSCT). Methods: We randomly selected 200 patients with coronary heat disease (BIM<25kg/m2), applied the scanning technology of regulating the dose of heart electric pulse (AUTO) on the 100 patients in group A. In this group for different heart rate we chose different full dose exposure time window. For the 100 patients in group B, we used conventional full dose (OFF) scan mode. The DSCT automatically selected the best time and phase to reconstruct the image. We used the 5 point system to evaluate the image quality, measured and compared the image noise and radiation dose. When P<0.05, the differences between the two groups have statistical significance. Results: The image quality scores between the two groups showed no significant difference (P > 0.05). The average image noise in group A is (41.76 ± 7.98) HU, in group B the average image noise is (43.97 ± 3.88) HU, the dif- ference between the two groups was not statistically significant (P>0.05). The average CTDIvol of group A and B were (20.63 ± 2.24) mGy, (38.11 ± 10.69) mGy, respectively, then P <0.01. The average DLP of group A and B are (235.75 ± 28.64) mGycm and (492.59 ± 125.49) mGycm respectively, then P <0.01, the dif- ference of radiation dose had statistical significance (P<0.05). Conclusions: For coronary artery imaging with DSCT the heart electric pulse (AUTO) regulation technology can meet the diagnostic requirements and effectively reduce the radiation dose.
Heart Murmur Recognition Based on Hidden Markov Model  [PDF]
Lisha Zhong, Jiangzhong Wan, Zhiwei Huang, Gaofei Cao, Bo Xiao
Journal of Signal and Information Processing (JSIP) , 2013, DOI: 10.4236/jsip.2013.42020

Heart murmur recognition and classification play an important role in the auscultative diagnosis. The method based on hidden markov model (HMM) was presented to recognize the heart murmur. The murmur was isolated on basis of the principle of wavelet analysis considering the time-frequency characteristics of the heart murmur. This method uses Mel frequency cepstral coefficient (MFCC) to extract representative features and develops hidden Markov model (HMM) for signal classification. The result shows that this method is able to recognize the murmur efficiently and superior to BP neural network (94.2% vs 82.8%). And the findings suggest that the method may have the potential to be used to assist doctors for a more objective diagnosis.

Study of Scanning Dose Optimization on Chest and Abdomen Enhanced CT Imaging  [PDF]
Zhiwei Huang, Lisha Zhong, Bo Xiao, Gaofei Cao
Journal of Signal and Information Processing (JSIP) , 2013, DOI: 10.4236/jsip.2013.42021

Objective: To investigate the correlation between radiation dose and radiation risk when patients are scanned by 64-slice spiral CT. Materials and Methods: SPSS 17.0 is used statistically for analyzing the patient’s scanning parameters, radiation dose of monitoring and examining the patients who are scanning of their abdomen, chest and pelvic in our affiliated hospital. Results: SPSS statistical analysis shows that the factor related to radiation dose is scanning layer; the basic characteristics such as height and heart rate don’t affect the patient’s scan dose directly. Conclusion: Increasing the delay time after injection can reduce the scan numbers and monitoring layers of the machine, thus reduce the patient’s radiation dose and tube’s exposure time.

Numerical Research of Aerodynamic Characteristic Effects of Base Jet on Supersonic Rocket
Juanmian Lei,Zhiwei Zheng,Can Huang
Advances in Mechanical Engineering , 2013, DOI: 10.1155/2013/757084
Abstract: Based on finite volume method, the interaction between base jet and supersonic flow around the rocket is simulated by Navier-Stokes equations with SST k-ω turbulence model and implicit algorithm. The pressure contours, the streamline patterns, and the variation of the aerodynamic characteristics of the rocket with the flying altitude, Mach number, and the angle of attack are shown and analyzed. Numerical results demonstrate that in supersonic flow, the base jet has a noticeable effect on the surface pressure of the body and the tails, leading to the decreases of the coefficients of the normal force, the pitching moment, and the pressure center. Furthermore, the higher the flying altitude, the more grave decreases of the coefficients of the normal force, the pitching moment and the pressure center. However, with the increase of Mach number, the more grave the decreases of the normal force coefficient and the pitch moment coefficient are found, while the less grave decrease is found with the pressure center coefficient. With the increase of the angle of attack, the more grave decreases are found with the coefficients of the normal force and the pitching moment, while the decrease of the pressure center coefficient remains almost the same. 1. Introduction In recent years, rockets of all kinds and patterns have turned out to be more and more important in modern local wars, as is seen in Iraq and Afghanistan, for their abrupt, violent, intensive fire and good maneuverability. Therefore, a lot of countries have committed to the development of rocket weapon systems, demanding not only more accurate operation, but also higher, faster, and farther launching conditions. Practically speaking, with the increase of the flying speed and the altitude, the aerodynamic characteristics of the rocket change greatly especially when the base jet is on in the active segment. Therefore, under the conditions of supersonic flow and high altitudes, the effects of the base jet on the aerodynamic characteristics and flying stability of rockets have become the hot topics for the researchers nowadays. As early as in the 1950s, the rocket engineers and scientists began to turn their attention to the free-flight investigation [1] over a Mach number range from 0.6 to 2.0 with the purpose of investigating the effects of the base jet on the drag force of 1/5-scale model of Hermes A-3A at . Their research demonstrated that the effects of the base jet on the drag characteristics are various due to different and . Since then, numerous experimental studies [2–11] have been done to determine
Construction and Analysis of SSH-cDNA Library from Leaves of Susceptible Rubber Clone Resistant to Powdery Mildew Induced by BTH  [PDF]
Chanjuan Luo, Zhiwei Fan, Yide Shen, Xiaoxia Li, Hanting Chang, Qiaoqiao Huang, Lizhen Liu
American Journal of Plant Sciences (AJPS) , 2013, DOI: 10.4236/ajps.2013.43068

To understand the mechanism of benzothiadiazole (BTH)-induced susceptible rubber clone resistance to powdery mildew on gene level, a differentially expressed cDNA library was constructed by suppression subtractive hybridization (SSH) with rubber Reyan 7-33-97 clone. The constructed cDNA library was high integrity through detection of the critical processes of SSH, such as efficiency of adaptor connection, subtraction and conversion, as well as the type of recombinant genes. The positive rate was 99% after identification with random 400 white spots. The size of the cDNA clone inserted fragments was various but most in 400 bp - 1000 bp. There were 23 cDNA sequences matching the function of energy and basic metabolism, signal transduction, membrane and transport, secondary metabolism and so on after detection of the 42 positive clone sequences selected randomly from the cDNA library and comparison on nucleic acid sequences in Genbank. 7 ESTs were logged in Genbank and accession numbers were GW873071 and GW874604- GW874610. The results implicated that BTH could effectively induced rubber tree resistance to powdery mildew through increasing expresses of defense-related genes in leaves of rubber tree susceptible clone. It should provide a new approach for rubber disease management.

Native Expanding Merremia boisiana Is Not More Allelopathic than Its Non-Expanding Congener M. vitifolia in the Expanded Range in Hainan  [PDF]
Qiaoqiao Huang, Yide Shen, Zhiwei Fan, Mingguang Li, Hanting Cheng, Xiaoxia Li
American Journal of Plant Sciences (AJPS) , 2013, DOI: 10.4236/ajps.2013.44096
Abstract: Exotic invaders may possess novel biochemical weapons that native plants do not have, and these novel biochemical weapons may be more allelopathic than those from native plants to other native competitors. During range expansion, native species also encounter many new plant competitors. Thus, allelochemicals from native expanding species may also be more novel and allelopathic than those from non-expanding species to other plant competitors in the expanded range. We test this hypothesis using the native expanding Merremia boisiana and its non-expanding congener M. vitifolia in year 2012 inthe expanded range inHainan. In petridish bioassays, we found that aqueous extracts of M. boisiana leaves were often less inhibitory or more stimulatory to seed germination and seedling growth of five vegetable species than those of M. vitifolia leaves. In pot culture, we also found that aqueous leaf extracts of the two congeners could both inhibit the growth of a naturally co-occurring plant Paederia scanden, but their effects did not differ from each other. These results indicate that while allelopathy may contribute to the competitive ability of M. boisiana, it may not act as a novel weapon explaining its success in the expanded range in Hainan.
Geostatistical Analysis of Soil Nutrients Based on GIS and Geostatistics in the Typical Plain and Hilly-Ground Area of Zhongxiang, Hubei Province  [PDF]
Yangbo Xu, Donglin Dong, Guobin Duan, Xuetao Yu, Zhiwei Yu, Wei Huang
Open Journal of Soil Science (OJSS) , 2013, DOI: 10.4236/ojss.2013.35026

Techniques of geostatistics are used to perform traditional statistical analysis and spatial structural analysis with ArcGIS, geostatistical software GS+ and statistical software SPSS in order to obtain the knowledge of characteristics of distribution and spatial variability of soil nutrients in different parts of Zhongxiang, Hubei Province. Some skewed values appeared during the analyses. To decrease the influence of those skewed values, domain processing and Box-Cox transformation were used. The results indicated spatial variability of Total N, Avail. P, rapidly-available potassium (R-Avail. K) and effective zinc (Effect. Zn) was strong, that of organic carbon (Org. C), effective molybdenum (Effect. Mo) and effective copper (Effect. Cu) was medium while that of others was weak. Fitted model of Total N, R-Avail. K and Effect. Mo was spherical model, that of Org. C and Effect. Zn was exponential model, while fitted model of Avail. P and Effect. Cu was Gaussian model. Ratio of variability caused by random factors to overall variability was large. What’s more, the ranges of spatial autocorrelation of soil nutrients had much difference. The smallest value was 3600 m in Effect. Zn while the largest was 77970 m in Org. C. Other characteristics were also included. The study is helpful to soil sampling design, to make people realize the influence of Han River to spatial variability of soil nutrients in this area, and to spatial interpolation and mapping.

Preliminary Observation and Significance of Changes on Rash of Skin Prick Test during SLIT  [PDF]
Weinian Lin, Jinchao Lin, Jun Liao, Runfeng Chen, Zhiwei Huang, Xiaodong Zhang, Wen Lin
International Journal of Otolaryngology and Head & Neck Surgery (IJOHNS) , 2018, DOI: 10.4236/ijohns.2018.74022
Abstract: Objective: To observe the changes on skin wheal and erythema of skin prick test for the patients with allergic rhinitis during SLIT. Methods: Since March 2010 the 103 cases of SLIT attacked by allergic rhinitis patients, divided into four age groups, respectively measured the diameter of skin wheal and erythema before treatment, six months, one year and 2 years after SLIT. The data were analyzed by analysis of variance method; P < 0.01 showed the difference was statistically significant. Results: The results showed that the most changes of skin erythema diameter were statistically significant in N1, N2, N3 age group during test observation compare with the data before SLIT (p < 0.01); and the most changes of allergen wheal diameter were not statistically significant, but the N4 group had no significant change of wheal and erythema diameter. Conclusion: Although most of the skin test wheal did not change significantly during the treatment of SLIT, the erythema reaction decreased to a certain extent, indicating that the intensity of histamine release may be reduced during the treatment.
Regeneration Capacity of Small Clonal Fragments of the Invasive Mikania micrantha H.B.K.: Effects of Burial Depth and Stolon Internode Length
Xiaoxia Li, Yide Shen, Qiaoqiao Huang, Zhiwei Fan, Dongdong Huang
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0084657
Abstract: The perennial stoloniferous herbaceous vine Mikania micrantha H.B.K. is among the most noxious exotic invaders in China and the world. Disturbance can fragment stolons of M. micrantha and disperse these fragments over long distances or bury them in soils at different depths. To test their regeneration capacity, single-node stolon fragments with stolon internode lengths of 0, 3, 6 and 12 cm were buried in soil at 0, 2, 5 and 8 cm depths, respectively. The fragments were growing for nine weeks, and their emergence status, growth and morphological traits were measured. The results indicated that increasing burial depth significantly decreased survival rate and increased the emergence time of the M. micrantha plants. At an 8-cm burial depth, very few fragments (2.19%) emerged and survived. Burial did not affect the total biomass and root to shoot ratio of the surviving M. micrantha plants that emerged from the 0- and 2-cm burial depths. Increasing internode length significantly increased survival rate and growth measures, but there was no interaction effect with burial depth for any traits measured. These results suggest that M. micrantha can regenerate from buried stolon fragments, and thus, disturbance may contribute to the spread of this exotic invader. Any human activities producing stolon fragments or facilitating dispersal should be avoided.
Overcome the Impairment of NK Cells for Icon and Antibody Immunotherapy of Cancer  [PDF]
Zhiwei Hu
Journal of Immune Based Therapies, Vaccines and Antimicrobials (JIBTVA) , 2013, DOI: 10.4236/jibtva.2013.21001
Abstract: Natural killer (NK) cells play an important role in innate immunity and in mediating antibody and Icon (an antibody-like factor VII/IgG1 Fc immunoconjugate, which, to our best knowledge, was the first therapeutic agent for dual targeting of both the tumor cells and tumor angiogenic endothelial cells) for cancer immunotherapy. However, a common yet often neglected observation and challenge in antibody immunotherapy is that NK cells are often impaired in cancer patients. Here we hypothesize that the impairment of NK cells significantly contributes to host resistance to antibody immunotherapy for cancer. In order for antibody and Icon to achieve their optimal therapeutic efficacy, we briefly reviewed the current strategies to enhance NK activity, including infusion of cytokines, vaccines or NK cells, and the use of dietary supplements. Moreover, from our point of view we identified some remaining challenges and propose to combine these NK-enhancing strategies with Icon or antibody to overcome NK impairment and ultimately to optimize the efficacy of Icon and antibody immunotherapy for cancer.
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