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Search Results: 1 - 10 of 3437 matches for " Yuri Kaulin "
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Biochemical enrichment and biophysical characterization of a taste receptor for L-arginine from the catfish, Ictalurus puntatus
William Grosvenor, Yuri Kaulin, Andrew I Spielman, Douglas L Bayley, D Lynn Kalinoski, John H Teeter, Joseph G Brand
BMC Neuroscience , 2004, DOI: 10.1186/1471-2202-5-25
Abstract: Both PHA-E and RCA-I almost exclusively labeled an 82–84 kDa protein band of an SDS-PAGE of solubilized barbel taste epithelial membranes. Further, both rhodamine-conjugated RCA-I and polyclonal antibodies raised to the 82–84 kDa electroeluted peptides labeled the apical region of catfish taste buds. Because of the specificity shown by RCA-I, lectin affinity was chosen as the first of a three-step procedure designed to enrich the presumed LGICR for L-Arg. Purified and CHAPS-solubilized taste epithelial membrane proteins were subjected successively to (1), lectin (RCA-I) affinity; (2), gel filtration (Sephacryl S-300HR); and (3), ion exchange chromatography. All fractions from each chromatography step were evaluated for L-Arg-induced ion channel activity by reconstituting each fraction into a lipid bilayer. Active fractions demonstrated L-Arg-induced channel activity that was inhibited by D-arginine (D-Arg) with kinetics nearly identical to those reported earlier for L-Arg-stimulated ion channels of native barbel membranes reconstituted into lipid bilayers. After the final enrichment step, SDS-PAGE of the active ion channel protein fraction revealed a single band at 82–84 kDa which may be interpreted as a component of a multimeric receptor/channel complex.The data are consistent with the supposition that the L-Arg receptor is a LGICR. This taste receptor remains active during biochemical enrichment procedures. This is the first report of enrichment of an active LGICR from the taste system of vertebrata.The initial event in taste transduction involves recognition of taste stimuli by plasma membrane-associated receptor proteins. These proteins are concentrated at the apical end of specialized neuro-epithelial cells (taste cells) found within multicellular end-organs known as taste buds [1,2]. The recognition binding sites for most taste stimuli face the exterior environment. The interaction of a taste stimulus with this recognition site triggers a chain of metabolic an
Prospects of Carbyne Applications in Microelectronics  [PDF]
Yuri Prazdnikov
Journal of Modern Physics (JMP) , 2011, DOI: 10.4236/jmp.2011.28100
Abstract: We design carbyne transistor which is integrable into the existing silicon technology and can be scaled up in a rather broad range -- starting from that prepared by us (by 0.5-mkm technology) up to the monomolecular one because the key mechanism here is the inter-chain charge transfer.
Superinjection from Oriented Carbyne as the Result of Landau Quantization in Giant Pseudo-Magnetic Field  [PDF]
Yuri Prazdnikov
Journal of Modern Physics (JMP) , 2013, DOI: 10.4236/jmp.2013.47134
Abstract:

The qualitative explanation of the earlier published experimental data was obtained within new energetic model of oriented carbyne. The conductivity spectrum and the superinjection effect feature Landau quantization in a giant pseudomagnetic field. The relativistic dispersion of carriers and non-dissipative character of their motion cause the effect of superinjection where carriers go upwards on an energetic ladder. Raman-spectra and other data point out to the fact that the plane of carriers’ motion is close to the carbyne-insulator interface. Quantum effects and on-surface conductivity allow considering oriented carbyne as an analogue of topological insulator.

Identification of Rotor Unbalance as Inverse Problem of Measurement  [PDF]
Yuri Menshikov
Advances in Pure Mathematics (APM) , 2013, DOI: 10.4236/apm.2013.39A1004
Abstract:

In this paper, the problem of identification of the characteristics of the rotor unbalance on two supports is investigated as the inverse problem of measurement. The vibration of rotor supports in two mutually perpendicular directions used as the initial information. The inverse problem is considered, taking into account the error of the mathematical description of rotor-bearings system. To obtain estimates of real unbalance characteristics, the hypothesis as to the exact solutions is applied. The method of Tikhonov regularization is used to obtain stable results. Test calculations are given to illustrate the proposed approach.

A Simplified Approach to the Problems of Room-Temperature Superconductivity  [PDF]
Yuri Prazdnikov
Journal of Modern Physics (JMP) , 2015, DOI: 10.4236/jmp.2015.64043
Abstract: An attempt to simplify the approach to the problems of room-temperature superconductors was done. The key factor has been highlighted—a giant spin-orbit interaction as a result of specific geometry of crystal. Considering oriented carbyne as an example, it was shown that maximal value of SOC was attained in low-dimensional systems. A qualitative model of superconductivity in the localized phase with “pseudo-magnetic field” and “Rashba effective field” as parameters was presented. Their correlation was shown via geometry of electric microfields of crystal. Oriented carbyne was presented as localized phase of room-temperature superconductor and the recipe of its transformation to macroscopic superconductivity was given.
Inverse Problem of Astrodynamics  [PDF]
Yuri Menshikov
World Journal of Mechanics (WJM) , 2015, DOI: 10.4236/wjm.2015.512023
Abstract: We consider the problem of determining the center of mass of an unknown gravitational body, using the disturbances in the motion of observed celestial bodies. In this paper an universal approach to obtain the approximate and stable estimate of problem solution is suggested. This approach can be used in other fields of Science. For example, it can be applied for investigation of interactions between fields of forces and elementary particles using known trajectories of elementary particles motions.
Electric Field and Hot Spots Formation on Divertor Plates  [PDF]
Yuri Igitkhanov, Boris Bazylev
Journal of Modern Physics (JMP) , 2011, DOI: 10.4236/jmp.2011.23020
Abstract: In this paper, we consider the intensive erosion of tungsten brush-type armour structures that face the plasma in divertor fusion reactors. Surface erosion caused by multiple transient events (ELMs, disruption, etc.) could lead to the formation of a corrugated wedge-type shape. Our analysis shows that the augmentation of surface roughness increases the electric field at the vicinity of the wedge-type tips, thus enabling the formation of electric arcs. Specifically, under reactor conditions, the breakdown of the sheath potential may trigger unipolar arcs that will strongly contaminate the plasma with the resulting tungsten ions. We show that the erosion caused by arcs is almost two orders of magnitude larger than that caused by DT ion sputtering and comparable with that caused by self-sputtering.
Scleractinian Corals and Reefs of Vietnam as a Part of the Pacific Reef Ecosystem  [PDF]
Yuri Ya Latypov
Open Journal of Marine Science (OJMS) , 2011, DOI: 10.4236/ojms.2011.12006
Abstract: The paper analyzes both published and unpublished results of the investigations of Vietnamese reef building corals and reefs performed in the last decades of the twentieth century and first decades twenty-first. The state of the art in the study of reef-building scleractinian corals and reefs is presented. The scleractinian fauna of Vietnam is shown to match in species diversity (350 species of 80 genera) the tropical coral fauna of the Indonesian–Malacca fertile center, from which Indo-Pacific reef-building corals originated. The whole Vietnam coast from the Gulf of Tonkin to the Gulf of Siam is a biogeographically single whole and is a part of the Indo-Polynesian Province of the Indo-Pacific Area.
Time-of-Flight Mass Spectrometry of Highly Ordered Carbyne  [PDF]
Yuri Evgenevich Prazdnikov
Journal of Modern Physics (JMP) , 2012, DOI: 10.4236/jmp.2012.39117
Abstract: Matrix-assisted laser desorption/ionization (MALDI) time-of-flight mass spectrometry was applied to a non-conven-tional object–highly ordered carbyne films. Mass spectra of both positive and negative ions were recorded in all tests. The spectra had a rather high number of hydrogen atom peaks and specific features indicative of hydrogen acting as a requisite stabilizer in the crystalline carbyne structure. A new model based on interchain dihydrogen bonds was proposed.
The Simulating of Power Electronics Systems with the Use of Explicit Numerical Schemes  [PDF]
Yuri Tanovitski, Gennady Kobzev
Applied Mathematics (AM) , 2013, DOI: 10.4236/am.2013.41A034
Abstract:

Automated simulating of power electronics systems is currently performed by means of nodal analysis method combined with implicit numerical integration schemes. Such method allows to find transient solutions, even when the integrated system is stiff, however, it leads to some difficulties when simulating big systems and sometimes to the deterioration of computations quality, that is reflected in decrease in accuracy, oscillations of solutions, which are not present in the initial model. This paper analyzes the shortcomings of this approach, and proposes to apply explicit numerical schemes with stability control on the integration step and with reduction of some of state variables. A brief description of the method of finding transient solutions and an example of the analysis are also given in the present paper.

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