oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2019 ( 4 )

2018 ( 9 )

2017 ( 15 )

2016 ( 19 )

Custom range...

Search Results: 1 - 10 of 5019 matches for " Yura Choi "
All listed articles are free for downloading (OA Articles)
Page 1 /5019
Display every page Item
Mutual space-frequency distribution of Gaussian signal
Yura Kozlovskii
Physics , 2008,
Abstract: Mutual space-frequency distribution is proposed and it is shown that Wigner and Weyl distribution functions are only particular cases of these distribution. Mutual distribution for Gaussian signal is analytically obtained. The simple connection between Wigner and Weyl distributions is established. It is shown that Wigner distribution forms as the rotational displacement of Weyl distribution on informational diagram of conjugate coordinates $(x;p)$ on an angle proportional to the mutual parameter $t$. The results of direct calculations of mutual distribution for Gaussian signal in the mutual domain are presented.
Solitons with nested structure over finite fields
Fumitaka Yura
Physics , 2014, DOI: 10.1088/1751-8113/47/32/325201
Abstract: We propose a solitonic dynamical system over finite fields that may be regarded as an analogue of the box-ball systems. The one-soliton solutions of the system, which have nested structures similar to fractals, are also proved. The solitonic system in this paper is described by polynomials, which seems to be novel. Furthermore, in spite of such complex internal structures, numerical simulations exhibit stable propagations before and after collisions among multiple solitons with preserving their patterns.
Entanglement Cost of Three-Level Antisymmetric States
Fumitaka Yura
Mathematics , 2003, DOI: 10.1088/0305-4470/36/15/104
Abstract: We show that the entanglement cost of the three-dimensional antisymmetric states is one ebit.
Hankel Determinant Solution for Elliptic Sequence
Fumitaka Yura
Computer Science , 2014,
Abstract: We show that the Hankel determinants of a generalized Catalan sequence satisfy the equations of the elliptic sequence. As a consequence, the coordinates of the multiples of an arbitrary point on the elliptic curve are expressed by the Hankel determinants.
DNF complexity of complete boolean functions
Yura Maximov
Computer Science , 2015,
Abstract: In this paper we analyse the complexity of boolean functions takes value 0 on a sufficiently small number of points. For many functions this leads to the analysis of a single function attains 0 only on unsigned representation of numbers from 1 to d for various d. Here we obtain a tight bounds on the DNF complexity of complete functions in terms of the number of literals and conjunctions. The method is based on a certain efficient approximation of the hypercube covering problem related to DNF complexity of a given boolean function.
Lower bounds on the DNF exception problem for short exception lists and related problems
Yura Maximov
Computer Science , 2015,
Abstract: In this paper we prowide lower bounds on the complexity of the DNF exception problem for short exception lists and hypercube covering problem. The method proposed is based on the relaxation of the initial problem to a certain linear programming problem. Some explicit bounds are provided for the case when exception list size is bounded above by a logarithm of dimension. The bound provided in this case is significantly stronger than the bounds known before.
Identification of a Novel Function of CX-4945 as a Splicing Regulator
Hyeongki Kim, Kwangman Choi, Hyunju Kang, So-Young Lee, Seung-Wook Chi, Min-Sung Lee, Jaehyoung Song, Donghwa Im, Yura Choi, Sungchan Cho
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0094978
Abstract: Alternative splicing is a nearly ubiquitous versatile process that controls gene expression and creates numerous protein isoforms with different functions from a single gene. The significance of alternative splicing has been confirmed by the increasing number of human diseases that are caused by misregulation of splicing events. Very few compounds, however, have been reported to act as inhibitors of alternative splicing, and their potential clinical use needs to be evaluated. Here, we report that CX-4945, a previously well-characterized inhibitor of casein kinase 2 (CK2) and a molecule currently in clinical trials (Phase II) for cancer treatment, regulates splicing in mammalian cells in a CK2-independent manner. Transcriptome-wide analysis using exon array also showed a widespread alteration in alternative splicing of numerous genes. We found that CX-4945 potently inhibits the Cdc2-like kinases (Clks) in vitro and in turn, leads to suppression of the phosphorylation of serine/arginine-rich (SR) proteins in mammalian cells. Surprisingly, the overall efficacy of CX-4945 on Clks (IC50 = 3–90 nM) was stronger than that of TG-003, the strongest inhibitor reported to date. Of the Clks, Clk2 was most strongly inhibited by CX-4945 in an ATP-competitive manner. Our research revealed an unexpected activity of the drug candidate CX-4945 as a potent splicing modulator and also suggested a potential application for therapy of diseases caused by abnormal splicing.
Correlation between amino acid residues converted by RNA editing and functional residues in protein three-dimensional structures in plant organelles
Kei Yura, Mitiko Go
BMC Plant Biology , 2008, DOI: 10.1186/1471-2229-8-79
Abstract: Here we study the relationship between amino acid residues encoded by edited codons and the structural characteristics of these residues within proteins, e.g., in protein-protein interfaces, elements of secondary structure, or protein structural cores. We find that the residues encoded by edited codons are significantly biased toward involvement in helices and protein structural cores. RNA editing can convert codons for hydrophilic to hydrophobic amino acids. Hence, only the edited form of an mRNA can be translated into a polypeptide with helix-preferring and core-forming residues at the appropriate positions, which is often required for a protein to form a functional three-dimensional (3D) structure.We have performed a novel analysis of the location of residues affected by RNA editing in proteins in plant organelles. This study documents that RNA editing sites are often found in positions important for 3D structure formation. Without RNA editing, protein folding will not occur properly, thus affecting gene expression. We suggest that RNA editing may have conferring evolutionary advantage by acting as a mechanism to reduce susceptibility to DNA damage by allowing the increase in GC content in DNA while maintaining RNA codons essential to encode residues required for protein folding and activity.RNA editing is a process that inserts, deletes and converts nucleotides in RNA after transcription, distinct from RNA splicing and 3' processing [1,2]. The insertion/deletion type of RNA editing was first discovered in protozoan kinetoplastid mRNAs [3], and the conversion type of RNA editing was first discovered in the mammalian mRNA encoding apolipoprotein B (apoB) [4,5], followed by its discovery in the plant mitochondrial mRNA for coxII [6] and chloroplast mRNA for rpl2 [7]. Since then, conversion editing has been mostly found in mRNAs transcribed from the mitochondrial and chloroplast genomes of land plants [8-12]. In the mitochondrion of Arabidopsis thaliana, at least 44
Incidence of oral indigenous bacteria in causative strains isolated from blood cultures in 759 laboratory-confirmed cases of bacteremia
Shinya Yura,Sadaya Matano
QScience Connect , 2012, DOI: 10.5339/connect.2012.5
Abstract: Background: The incidence of oral indigenous bacteria in cases of bacteremia has been reported in only a few studies. We investigated the annual incidence of oral indigenous bacteria isolated in blood cultures from patients with bacteremia and call into consideration the impact of oral health measures implemented at our facility. Methods: In the period from 2001 to 2006, 759 laboratory-confirmed cases of bacteremia were reported and subsequently analyzed in this study. The incidences of the causative strain and oral indigenous bacteria in blood cultures were studied by year Results: In 759 cases of bacteremia, oral streptococci were noted in 14 (1.8%), and anaerobic bacteria were noted in 9 (1.2%). The population of microorganisms did not change significantly during the study period. Conclusions: In a previous report, oral streptococci accounted for 3.8% of those under investigation. In this study, the incidence of oral streptococci was significantly low, 1.8% specifically. A focus on oral health care at our hospital may account for a reduced incidence of oral streptococci bacteremia.
On a Periodic Soliton Cellular Automaton
Fumitaka Yura,Tetsuji Tokihiro
Physics , 2001, DOI: 10.1088/0305-4470/35/16/317
Abstract: We propose a box and ball system with a periodic boundary condition (pBBS). The time evolution rule of the pBBS is represented as a Boolean recurrence formula, an inverse ultradiscretization of which is shown to be equivalent with the algorithm of the calculus for the 2Nth root. The relations to the pBBS of the combinatorial R matrix of ${U'}_q(A_N^{(1)})$ are also discussed.
Page 1 /5019
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.