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Search Results: 1 - 10 of 52922 matches for " Yung-Kang Wu "
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First-attack pediatric hypertensive crisis presenting to the pediatric emergency department
Wen-Chieh Yang, Lu-Lu Zhao, Chun-Yu Chen, Yung-Kang Wu, Yu-Jun Chang, Han-Ping Wu
BMC Pediatrics , 2012, DOI: 10.1186/1471-2431-12-200
Abstract: This was a retrospective study conducted from 2000 to 2007 in pediatric patients aged 18 years and younger with a diagnosis of hypertensive crisis at the ED. All patients were divided into four age groups (infants, preschool age, elementary school age, and adolescents), and two severity groups (hypertensive urgency and hypertensive emergency). BP levels, etiology, severity, and clinical manifestations were analyzed by age group and compared between the hypertensive emergency and hypertensive urgency groups.The mean systolic/diastolic BP in the hypertensive crisis patients was 161/102 mmHg. The major causes of hypertensive crisis were essential hypertension, renal disorders and endocrine/metabolic disorders. Half of all patients had a single underlying cause, and 8 had a combination of underlying causes. Headache was the most common symptom (54.5%), followed by dizziness (45.5%), nausea/vomiting (36.4%) and chest pain (29.1%). A family history of hypertension was a significant predictive factor for the older patients with hypertensive crisis. Clinical manifestations and severity showed a positive correlation with age. In contrast to diastolic BP, systolic BP showed a significant trend in the older children.Primary clinicians should pay attention to the pediatric patients who present with elevated blood pressure and related clinical hypertensive symptoms, especially headache, nausea/vomiting, and altered consciousness which may indicate that appropriate and immediate antihypertensive medications are necessary to prevent further damage.It has been demonstrated that high blood pressure (BP) contributes to the early development of cardiovascular structural and functional changes in children [1,2]. With increasingly high BP, autoregulation eventually fails, leading to damage of the vascular wall and further organ hypoperfusion. Hypertensive crisis is a critical condition characterized by a rapid, inappropriate and symptomatic elevated BP, and is categorized as hypertensiv
Optimization of thermoelectric performance of SrSi2-based alloys via the modification in band structure and phonon-point-defect scattering
Yung-Kang Kuo,Balakrishnan Ramachandran
Frontiers in Chemistry , 2014, DOI: 10.3389/fchem.2014.00106
Abstract: Thermoelectric properties of alkaline-earth-metal disilicides are strongly dependent on their electronic band structure in the vicinity of the Fermi level. In particular, the strontium disilicide, SrSi2 with a narrow band gap of about few tens of meV is composed of non-toxic, naturally abundant elements, and its thermoelectric properties are very sensitive to the substitution/alloying with third elements. In this article, we summarize the thermoelectric performance of substituted and Sr-deficient/Sr-rich SrSi2 alloys to realize the high thermoelectric figure-of-merit (ZT) for practical applications in the electronic and thermoelectric aspects, and also to explore the alternative routes to further improve its ZT value.
Integrating Real-time Bridge Scouring Monitoring System with Mobile Location-Based Services
Yung-Bin Lin, Kuo-Chun Chang, Chun-Chung Chen, Shih-Cheng Wong, Lu-sheng Lee, Yung-Kang Wang, Meng-Huang Gu
International Journal of Automation and Smart Technology , 2011, DOI: 10.5875/ausmt.v1i2.127
Abstract: Typhoons and torrential rains not only erode river beds and coasts and damage river-crossing structures, but also affect the geomorphology and topography of rivers and coasts. Additionally, typhoons and torrential rains cause debris flows and flooding in metropolitan areas and threaten the safety of people’s lives and properties. Disaster prevention and reduction of damage caused by typhoons and torrential rains have always been a crucial task of government agencies. Bridges in Taiwan are generally old and have insufficient shock resistance; some bridge foundations are also severely eroded and exposed. Because of global climate changes in recent years, rainfall has become comparatively heavy and rapid. Furthermore, the soil in mountain areas has softened because of factors such as earthquakes or human developments. Debris rushes down with rain every time a torrential rain strikes, significantly impacting the safety of bridges downstream. Although government bridge management units have made budget plans to progressively renovate dangerous old bridges, these bridges are still being use for traffic and transportation. These dangerous old bridges pose a serious threat to the safety of people when an earthquake, typhoon, or flood occurs. During typhoons and floods, increased water levels and changes of the scouring depths have dramatic effects on the safety of bridges. The bridge maintenance unit currently uses the water level and water flow conditions as references when determining whether to close a bridge; however, this is not a good permanent solution. A bridge scour monitoring and warning system that is stable, reliable, and operates normally under flood attacks is required for on-site installation and verification. In recent years, the applied technologies of smart phones have expanded beyond entertainment and communication. Mobile communications are used to transmit relevant information to bridge maintenance and management units and road users when a bridge is potentially damaged. The instant conveying of information allows the bridge management units to implement instant disaster rescue response measures and to notify road users to avoid the dangerous road sections, protecting people’s lives and properties.


物理学报 , 1988,
Abstract: Photoluminescence technique are used to diagnose the quality of quantum wells. The influences on the fluorescence spectra of quantum wells due to thickness fluctuations of quantum wells, fluctuation of aluminium content, various defects, and unintentional impurities, are discussed. And inversely, the possible reasons causing degradation of quantum wells are deduced from the photoluminescence spectra. To some extent the diagnosis can provide certain basic information for improving the molecular beam epitaxy technology.
Antiosteoporotic Activity of Dioscorea alata L. cv. Phyto through Driving Mesenchymal Stem Cells Differentiation for Bone Formation
Kang-Yung Peng,Lin-Yea Horng,Hui-Ching Sung,Hui-Chuan Huang,Rong-Tsun Wu
Evidence-Based Complementary and Alternative Medicine , 2011, DOI: 10.1155/2011/712892
Abstract: The aim of this study was to evaluate the effect of an ethanol extract of the rhizomes of Dioscorea alata L. cv. Phyto, Dispo85E, on bone formation and to investigate the mechanisms involved. Our results showed that Dispo85E increased the activity of alkaline phosphatase (ALP) and bone nodule formation in primary bone marrow cultures. In addition, Dispo85E stimulated pluripotent C3H10T1/2 stem cells to differentiate into osteoblasts rather than adipocytes. Our in vivo data indicated that Dispo85E promotes osteoblastogenesis by increasing ALP activity and bone nodule formation in both intact and ovariectomized (OVX) mice. Microcomputed tomography (μCT) analysis also showed that Dispo85E ameliorates the deterioration of trabecular bone mineral density (tBMD), trabecular bone volume/total volume (BV/TV), and trabecular bone number (Tb.N) in OVX mice. Our results suggested that Dispo85E is a botanical drug with a novel mechanism that drives the lineage-specific differentiation of bone marrow stromal cells and is a candidate drug for osteoporosis therapy. 1. Introduction Osteoporosis is a prevalent bone disease that is defined by a low bone mass and an increased risk of fractures [1]. Adequate regulation of bone remodeling in adulthood is essential to maintain a healthy bone mass [2]. However, an imbalance between bone formation and bone resorption in pathological conditions or during the aging process can result in conditions that lead to osteoporosis [3]. In the past, the process of bone remodeling was considered to be regulated by two major cell types: bone-forming osteoblasts and bone-resorbing osteoclasts [4]. Currently available agents used to treat osteoporosis include estrogen, raloxifene, the bisphosphonates (e.g., alendronate and risedronate, etc.), and calcitonin. Their mechanisms are based on the inhibition of osteoclastic bone resorption to prevent further bone loss [5]. However, many osteoporotic patients already had lost a substantial amount of bone mass before diagnosis [6]. Furthermore, many side effects of antiresorptive agents have been reported, causing many patients to discontinue their use [7–9]. Drugs with anabolic effects have received much recent attention for osteoporosis therapy. These pharmacologic agents can ultimately stimulate new bone formation, enhance bone density, reduce bone fracture, and promote bone health. Currently, there is only one available anabolic agent on the market approved for the treatment of osteoporosis, recombinant human parathyroid hormone (hPTH). However, hPTH is limited for use in cases of severe
Angiopoietin-2 Is Associated with Albuminuria and Microinflammation in Chronic Kidney Disease
Fan-Chi Chang, Tai-Shuan Lai, Chih-Kang Chiang, Yung-Ming Chen, Ming-Shiou Wu, Tzong-Shinn Chu, Kwan-Dun Wu, Shuei-Liong Lin
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0054668
Abstract: Although cardiovascular disease (CVD) is the leading cause of mortality in patients with chronic kidney disease (CKD), the pathophysiology is not thoroughly understood. Given that elevated albuminuria or circulating angiopoietin-2 associates with CVD and mortality in CKD patients, we were intrigued by the relationship between albuminuria and angiopoietin-2. A total of 416 patients with CKD stages 3 to 5 were stratified by urine albumin-creatinine ratio as normoalbuminuria (<30 mg/g), microalbuminuria (30–300 mg/g), or macroalbuminuria (>300 mg/g). The levels of plasma angiopoietin-2 and vascular endothelial growth factor (VEGF) increased, and soluble Tie-2 decreased in the subgroups of albuminuria; whereas angiopoietin-1 did not change. Linear regression showed a positive correlation between urine albumin-creatinine ratio (ACR) and plasma angiopoietin-2 (correlation coefficient r = 0.301, 95% confidence interval 0.211–0.386, P<0.0001), but not between ACR and VEGF or soluble Tie-2. Multivariate linear regression analysis showed that plasma angiopoietin-2 was independently associated with ACR (P = 0.025). Furthermore, plasma angiopoietin-2 was positively correlated with high sensitive C-reactive protein (r = 0.114, 95% confidence interval 0.018–0.208, P = 0.020). In conclusion, plasma angiopoietin-2 was associated with albuminuria and markers of systemic microinflammation in CKD patients. Although previous evidence has shown that angiopoietin-2 destabilizes vasculature and induces inflammation in different scenarios, further study will be required to delineate the role of angiopoietin-2 in albuminuria and microinflammation in CKD patients.
Theoretically Catalytic Synthesis of 5-Nitro-1,2,4-Triazol-3-One in Inert Gas Clustered System (X6, X = He, Ne)  [PDF]
Min-Hsien Liu, Ming-Yung Wu
Open Journal of Physical Chemistry (OJPC) , 2012, DOI: 10.4236/ojpc.2012.22015
Abstract: Inert gas-clustered systems (Xn, X = He, Ne, Ar and n = 2 - 20) were established in this study and their stability as a result of interparticulate interaction was examined. Ferric chloride and ferrous oxides were used as catalysts to promote reaction, and 5-nitro-1,2,4-triazol-3-one (NTO) was theoretically synthesized under an inert gas (X6)-clustered environment in this study. The raw material, urea, initially underwent chlorination using chlorine as the reagent, followed by amination, formylation and nitration. Reaction routes closely related to the experimental processes were successfully constructed, and the corresponding energy barriers were estimated for each elementary reaction. The findings revealed that the average errors in the B3LYP/6-31G(d, p)-calculated geometry and vibrational frequency of NTO in an Ne6 system relative to the observed values were 0.83% and 1.84%, respectively. The neon gas-clustered system achieved greater stabilization, which results from the difference in self-consistent field energy (ESCF), than the corresponding stabilization acquired in a helium- or argon-based system. Ferric chloride serves as a good catalyst to reduce the energy barrier of the chlorination reaction, and ferrous oxide is suitable for catalyzing the amination, formylation and nitration reactions, although nitric acid is the better agent for nitration. The catalytic Ne6-clustered reaction system is suggested to be a more feasible pathway for the synthesis of NTO.
Factors Influencing the Use of Mobile Financial Services: Evidence from Taiwan  [PDF]
Feng-Shang Wu, Yung-Shen Yen
Modern Economy (ME) , 2014, DOI: 10.4236/me.2014.513113
Abstract: Mobile service innovation has become a critical issue in the financial sectors. Currently, many banks in Taiwan have developed various mobile services for their customers. However, mobile services in financial sectors are different from Internet services because of the mobility. First, mobile services enable mobile extensions of existing electronic services and new services that are valuable to users on the move. Second, most people have their own, personal mobile devices in the hands, but they may not have the computers with them anytime. Although consumers’ technology acceptance has been examined in the context of e-commerce, mobile financial services are gained scant attention. Thus, this study aims to explore the factors influencing the use of mobile financial services (MFS). We conducted a qualitative research in depth, and investigated a renowned bank in Taiwan which developed various MFS for customers. The findings reveal that perceived mobility and personal habit are two important antecedents influencing the use of MFS. Mobility positively affects perceived ease-of-use and perceived usefulness, which in turn influence the use of MFS. Furthermore, personal habit positively affects the use of MFS.
Development of Unilateral Piriformis Syndrome in a Female with Congenital Leg Length Discrepancy  [PDF]
Chia-Hung Sun, Shao-Chi Lu, Yung-Tsan Wu, Shin-Tsu Chang
Open Journal of Orthopedics (OJO) , 2012, DOI: 10.4236/ojo.2012.24025

Background: This is a rare case of piriformis syndrome. We discuss the patient’s symptoms, imaging study results, laboratory examination findings, and prescribed treatment in an attempt to determine the possible mechanisms or reasons for this patient’s development of piriformis syndrome. Methods: The patient is a 22-year-old female soldier who was admitted for lower back pain with soreness radiating to her right buttock and right lower extremity. We found that she had leg length discrepancy under X-ray finding. She was diagnosed piriformis syndrome by physical examination and Magenetic Resonance Image. Results: We performed scanography for lower extremities revealed a left femur length of 42.7 cm, a right femur length of 43.3 cm, a left tibia length of 33.2 cm, and a right tibia length of 33.6 cm; her left lower extremity was 1 cm shorter than her right. The MRI of sacrum also reveals hypertrophy of right piriformis muscle. Conclusions: Piriformis syndrome might be caused by short-term compensation in congenital leg length discrepancy. The patient with leg length discrepancy changed posture when standing, walking, and running. These compensation postures could lead to abnormality position of bones where there is insertion of the muscle.

Concomitant Retroperitoneal Intramuscular Hemangioma and Intravascular Papillary Endothelial Hyperplasia: An Unusual Case Report  [PDF]
Ching-Yueh Lin, Yu-Chun Lin, Liang-Cheng Chen, Yung-Tsan Wu
Case Reports in Clinical Medicine (CRCM) , 2014, DOI: 10.4236/crcm.2014.35060

Primary retroperitoneal tumors are rare, and benign retroperitoneal tumors are exceptionally rare. Herein, we present a very rare case of benign concomitant retroperitoneal intramuscular hemangioma and intravascular papillary endothelial hyperplasia, with the unusual presentation of lumbosacral plexopathy. After surgical treatment and rehabilitation, the patient recovered uneventfully. This case report should serve to remind physicians of the rare condition of a retroperitoneal tumor leading to a neurological deficit.

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